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Pulmonary vein stenosis

MedGen UID:
473065
•Concept ID:
C0340756
•
Disease or Syndrome
Synonyms: Pulmonary Vein Stenoses; Pulmonary Vein Stenosis; Stenoses, Pulmonary Vein; Stenosis, Pulmonary Vein; Vein Stenoses, Pulmonary; Vein Stenosis, Pulmonary
SNOMED CT: Pulmonary vein stenosis (234062003)

Definition

Obstruction of the pulmonary vein in one or multiple sites. The obstruction is the result of wall thickening and narrowing of the lumen of the vein. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPulmonary vein stenosis

Professional guidelines

PubMed

Pathogenesis, Evaluation, and Management of Pulmonary Vein Stenosis: JACC Review Topic of the Week.
Simard T, Sarma D, Miranda WR, Jain CC, Anderson JH, Collins JD, El Sabbagh A, Jhand A, Peikert T, Reeder GS, Munger TM, Packer DL, Holmes DR
J Am Coll Cardiol 2023 Jun 20;81(24):2361-2373. doi: 10.1016/j.jacc.2023.04.016. PMID: 37316116
Primary pulmonary vein stenosis during infancy: state of the art review.
Frank DB, Levy PT, Stiver CA, Boe BA, Baird CW, Callahan RM, Smith CV, Vanderlaan RD, Backes CH
J Perinatol 2021 Jul;41(7):1528-1539. Epub 2021 Mar 5 doi: 10.1038/s41372-021-01008-7. PMID: 33674714
Pulmonary vein stenosis: Treatment and challenges.
Vanderlaan RD, Rome J, Hirsch R, Ivy D, Caldarone CA
J Thorac Cardiovasc Surg 2021 Jun;161(6):2169-2176. Epub 2020 Jun 27 doi: 10.1016/j.jtcvs.2020.05.117. PMID: 32763037

Recent clinical studies

Etiology

Interventions for Pulmonary Vein Stenosis.
Hsien S, Krishnan U, Petit CJ
Interv Cardiol Clin 2024 Jul;13(3):431-438. Epub 2024 Apr 12 doi: 10.1016/j.iccl.2024.03.003. PMID: 38839175
Pulmonary vein narrowing after pulsed field versus thermal ablation.
Mansour M, Gerstenfeld EP, Patel C, Natale A, Whang W, Cuoco FA, Mountantonakis SE, Gibson DN, Harding JD, Holland SK, Achyutha AB, Schneider CW, Mugglin AS, Albrecht EM, Stein KM, Lehmann JW, Reddy VY
Europace 2024 Feb 1;26(2) doi: 10.1093/europace/euae038. PMID: 38305503Free PMC Article
Systemic Sirolimus Therapy for Infants and Children With Pulmonary Vein Stenosis.
Patel JD, Briones M, Mandhani M, Jones S, Suthar D, Gray R, Pettus J, McCracken C, Thomas A, Petit CJ
J Am Coll Cardiol 2021 Jun 8;77(22):2807-2818. doi: 10.1016/j.jacc.2021.04.013. PMID: 34082911
Treatment of Congenital and Acquired Pulmonary Vein Stenosis.
Suntharos P, Prieto LR
Curr Cardiol Rep 2020 Oct 3;22(11):153. doi: 10.1007/s11886-020-01395-x. PMID: 33009955
Pulmonary Vein Isolation With Very High Power, Short Duration, Temperature-Controlled Lesions: The QDOT-FAST Trial.
Reddy VY, Grimaldi M, De Potter T, Vijgen JM, Bulava A, Duytschaever MF, Martinek M, Natale A, Knecht S, Neuzil P, Pürerfellner H
JACC Clin Electrophysiol 2019 Jul;5(7):778-786. Epub 2019 May 8 doi: 10.1016/j.jacep.2019.04.009. PMID: 31320006

Diagnosis

Pulmonary vein narrowing after pulsed field versus thermal ablation.
Mansour M, Gerstenfeld EP, Patel C, Natale A, Whang W, Cuoco FA, Mountantonakis SE, Gibson DN, Harding JD, Holland SK, Achyutha AB, Schneider CW, Mugglin AS, Albrecht EM, Stein KM, Lehmann JW, Reddy VY
Europace 2024 Feb 1;26(2) doi: 10.1093/europace/euae038. PMID: 38305503Free PMC Article
Pathogenesis, Evaluation, and Management of Pulmonary Vein Stenosis: JACC Review Topic of the Week.
Simard T, Sarma D, Miranda WR, Jain CC, Anderson JH, Collins JD, El Sabbagh A, Jhand A, Peikert T, Reeder GS, Munger TM, Packer DL, Holmes DR
J Am Coll Cardiol 2023 Jun 20;81(24):2361-2373. doi: 10.1016/j.jacc.2023.04.016. PMID: 37316116
Paroxysmal Atrial Fibrillation Ablation Using a Novel Variable-Loop Biphasic Pulsed Field Ablation Catheter Integrated With a 3-Dimensional Mapping System: 1-Year Outcomes of the Multicenter inspIRE Study.
Duytschaever M, De Potter T, Grimaldi M, Anic A, Vijgen J, Neuzil P, Van Herendael H, Verma A, Skanes A, Scherr D, Pürerfellner H, Rackauskas G, Jaïs P, Reddy VY; inspIRE Trial Investigators
Circ Arrhythm Electrophysiol 2023 Mar;16(3):e011780. Epub 2023 Feb 3 doi: 10.1161/CIRCEP.122.011780. PMID: 36735937Free PMC Article
Systemic Sirolimus Therapy for Infants and Children With Pulmonary Vein Stenosis.
Patel JD, Briones M, Mandhani M, Jones S, Suthar D, Gray R, Pettus J, McCracken C, Thomas A, Petit CJ
J Am Coll Cardiol 2021 Jun 8;77(22):2807-2818. doi: 10.1016/j.jacc.2021.04.013. PMID: 34082911
Pulmonary vein stenosis: Treatment and challenges.
Vanderlaan RD, Rome J, Hirsch R, Ivy D, Caldarone CA
J Thorac Cardiovasc Surg 2021 Jun;161(6):2169-2176. Epub 2020 Jun 27 doi: 10.1016/j.jtcvs.2020.05.117. PMID: 32763037

Therapy

Pulmonary vein narrowing after pulsed field versus thermal ablation.
Mansour M, Gerstenfeld EP, Patel C, Natale A, Whang W, Cuoco FA, Mountantonakis SE, Gibson DN, Harding JD, Holland SK, Achyutha AB, Schneider CW, Mugglin AS, Albrecht EM, Stein KM, Lehmann JW, Reddy VY
Europace 2024 Feb 1;26(2) doi: 10.1093/europace/euae038. PMID: 38305503Free PMC Article
Paroxysmal Atrial Fibrillation Ablation Using a Novel Variable-Loop Biphasic Pulsed Field Ablation Catheter Integrated With a 3-Dimensional Mapping System: 1-Year Outcomes of the Multicenter inspIRE Study.
Duytschaever M, De Potter T, Grimaldi M, Anic A, Vijgen J, Neuzil P, Van Herendael H, Verma A, Skanes A, Scherr D, Pürerfellner H, Rackauskas G, Jaïs P, Reddy VY; inspIRE Trial Investigators
Circ Arrhythm Electrophysiol 2023 Mar;16(3):e011780. Epub 2023 Feb 3 doi: 10.1161/CIRCEP.122.011780. PMID: 36735937Free PMC Article
Pulmonary vein stenosis after radiofrequency ablation.
Gomes ACP, Medeiros AK, Marchiori E
J Bras Pneumol 2022 Jul 8;48(3):e20220013. doi: 10.36416/1806-3756/e20220013. PMID: 35830053Free PMC Article
Systemic Sirolimus Therapy for Infants and Children With Pulmonary Vein Stenosis.
Patel JD, Briones M, Mandhani M, Jones S, Suthar D, Gray R, Pettus J, McCracken C, Thomas A, Petit CJ
J Am Coll Cardiol 2021 Jun 8;77(22):2807-2818. doi: 10.1016/j.jacc.2021.04.013. PMID: 34082911
Pulmonary Vein Isolation With Very High Power, Short Duration, Temperature-Controlled Lesions: The QDOT-FAST Trial.
Reddy VY, Grimaldi M, De Potter T, Vijgen JM, Bulava A, Duytschaever MF, Martinek M, Natale A, Knecht S, Neuzil P, Pürerfellner H
JACC Clin Electrophysiol 2019 Jul;5(7):778-786. Epub 2019 May 8 doi: 10.1016/j.jacep.2019.04.009. PMID: 31320006

Prognosis

Comprehensive review of pulmonary vein stenosis post-atrial fibrillation ablation: diagnosis, management, and prognosis.
Tokuda M, Ogawa T, Tokutake K, Yamashita S, Yoshimura M, Yamane T
Cardiovasc Interv Ther 2024 Oct;39(4):412-420. Epub 2024 Aug 6 doi: 10.1007/s12928-024-01033-1. PMID: 39107545
Clinical Outcomes, Predictors, and Surgical Management of Primary Pulmonary Vein Stenosis.
Feng Z, Mao F, Ma K, He F, Yang Y, Yuan J, Zhang S, Zhang B, He Q, Li S
Ann Thorac Surg 2022 Apr;113(4):1239-1247. Epub 2021 Mar 18 doi: 10.1016/j.athoracsur.2021.03.015. PMID: 33745903
Treatment of Congenital and Acquired Pulmonary Vein Stenosis.
Suntharos P, Prieto LR
Curr Cardiol Rep 2020 Oct 3;22(11):153. doi: 10.1007/s11886-020-01395-x. PMID: 33009955
Intraluminal Pulmonary Vein Stenosis in Children: A "New" Lesion.
Nasr VG, Callahan R, Wichner Z, Odegard KC, DiNardo JA
Anesth Analg 2019 Jul;129(1):27-40. doi: 10.1213/ANE.0000000000003924. PMID: 30451723
Pulmonary vein stenosis complicating radiofrequency catheter ablation for atrial fibrillation: A literature review.
Edriss H, Denega T, Test V, Nugent K
Respir Med 2016 Aug;117:215-22. Epub 2016 Jun 15 doi: 10.1016/j.rmed.2016.06.014. PMID: 27492534

Clinical prediction guides

Doppler Echocardiographic Features of Pulmonary Vein Stenosis in Ex-Preterm Children.
Lin Y, Amin EK, Keller RL, Teitel DF, Nawaytou HM
J Am Soc Echocardiogr 2022 Apr;35(4):435-442. Epub 2022 Jan 2 doi: 10.1016/j.echo.2021.12.015. PMID: 34986343
Clinical Outcomes, Predictors, and Surgical Management of Primary Pulmonary Vein Stenosis.
Feng Z, Mao F, Ma K, He F, Yang Y, Yuan J, Zhang S, Zhang B, He Q, Li S
Ann Thorac Surg 2022 Apr;113(4):1239-1247. Epub 2021 Mar 18 doi: 10.1016/j.athoracsur.2021.03.015. PMID: 33745903
Treatment of Congenital and Acquired Pulmonary Vein Stenosis.
Suntharos P, Prieto LR
Curr Cardiol Rep 2020 Oct 3;22(11):153. doi: 10.1007/s11886-020-01395-x. PMID: 33009955
Management outcomes of primary pulmonary vein stenosis.
Rosenblum JM, Altin HF, Gillespie SE, Bauser-Heaton H, Kanter KA, Sinha R, Cory M, Alsoufi B
J Thorac Cardiovasc Surg 2020 Mar;159(3):1029-1036.e1. Epub 2019 Sep 25 doi: 10.1016/j.jtcvs.2019.08.105. PMID: 31648829
Intraluminal Pulmonary Vein Stenosis in Children: A "New" Lesion.
Nasr VG, Callahan R, Wichner Z, Odegard KC, DiNardo JA
Anesth Analg 2019 Jul;129(1):27-40. doi: 10.1213/ANE.0000000000003924. PMID: 30451723

Recent systematic reviews

Pulmonary Vein Stenosis-Balloon Angioplasty Versus Stenting: A Systematic Review and Meta-Analysis.
Almakadma AH, Sarma D, Hassett L, Miranda W, Alkhouli M, Reeder GS, Munger TM, Packer DL, Simard T, Holmes DR Jr
JACC Clin Electrophysiol 2022 Oct;8(10):1323-1333. Epub 2022 Sep 16 doi: 10.1016/j.jacep.2022.08.008. PMID: 36117046
A systematic review and meta-analysis of catheter ablation for atrial fibrillation.
Wang P, He W, Li C, Xiang T, Yang Q, Chen Q
Ann Palliat Med 2021 Oct;10(10):10542-10555. doi: 10.21037/apm-21-2313. PMID: 34763501
Pulmonary cuff dysfunction after lung transplant surgery: A systematic review of the evidence and analysis of its clinical implications.
Kumar N, Essandoh M, Bhatt A, Whitson BA, Sawyer TR, Flores A, Awad H, Dimitrova G, Gorelik L, Bhandary S, Perez WJ, Iyer MH, Stein E, Fiorini K, Turner K, Saklayen S, Hussain N
J Heart Lung Transplant 2019 May;38(5):530-544. Epub 2019 Jan 7 doi: 10.1016/j.healun.2019.01.005. PMID: 30718043
Pulmonary Vein Stenosis in Infants: A Systematic Review, Meta-Analysis, and Meta-Regression.
Backes CH, Nealon E, Armstrong AK, Cua CL, Mitchell C, Krishnan U, Vanderlaan RD, Song MK, Viola N, Smith CV, McConnell PI, Rivera BK, Bridge J
J Pediatr 2018 Jul;198:36-45.e3. Epub 2018 Apr 9 doi: 10.1016/j.jpeds.2018.02.030. PMID: 29650415
Transesophageal echocardiography for the diagnosis of pulmonary vein stenosis after catheter ablation of atrial fibrillation: a systematic review.
Stavrakis S, Madden GW, Stoner JA, Sivaram CA
Echocardiography 2010 Oct;27(9):1141-6. doi: 10.1111/j.1540-8175.2010.01250.x. PMID: 20678129

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