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Drug-induced gingival hyperplasia

MedGen UID:
473100
Concept ID:
C0399439
Disease or Syndrome
Synonyms: Drug Induced Gingival Hyperplasia; Hyperplasia of gingiva caused by drug
SNOMED CT: Drug-induced gingival hyperplasia (93434009); Hyperplasia of gingiva caused by drug (93434009)

Definition

Overgrowth of the gingival tissue caused by phenytoin, cyclosporine A, and calcium channel blockers. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDrug-induced gingival hyperplasia

Professional guidelines

PubMed

Shaikh S, Dragan IF, Nevius A, Mehta N, Karimbux N
J Evid Based Dent Pract 2018 Dec;18(4):290-297. Epub 2018 Feb 13 doi: 10.1016/j.jebdp.2018.02.001. PMID: 30514443

Recent clinical studies

Etiology

Goriuc A, Foia LG, Minea B, Luchian AI, Surdu AE, Toma V, Costuleanu M, Mârţu I
Rom J Morphol Embryol 2017;58(4):1371-1376. PMID: 29556630
Cune MS, Strooker H, van der Reijden WA, de Putter C, Laine ML, Verhoeven JW
Int J Oral Maxillofac Implants 2009 May-Jun;24(3):534-40. PMID: 19587878
Sonmez S, Cavdar C, Gunduz C, Nizam N, Biray C, Atila K, Camsari T
Transplant Proc 2008 Jan-Feb;40(1):181-3. doi: 10.1016/j.transproceed.2007.11.064. PMID: 18261580
Meisel P, Schwahn C, John U, Kroemer HK, Kocher T
Br J Clin Pharmacol 2005 Nov;60(5):552-9. doi: 10.1111/j.1365-2125.2005.02485.x. PMID: 16236046Free PMC Article
Iacopino AM, Doxey D, Cutler CW, Nares S, Stoever K, Fojt J, Gonzales A, Dill RE
J Periodontol 1997 Jan;68(1):73-83. doi: 10.1902/jop.1997.68.1.73. PMID: 9029455

Diagnosis

Reddy SC, Midha N, Chhabra V, Kumar D, Bohra GK
Curr Drug Saf 2022;17(3):281-283. doi: 10.2174/1574886316666211122125215. PMID: 34809550
Shaikh S, Dragan IF, Nevius A, Mehta N, Karimbux N
J Evid Based Dent Pract 2018 Dec;18(4):290-297. Epub 2018 Feb 13 doi: 10.1016/j.jebdp.2018.02.001. PMID: 30514443
Botha PJ
J Dent Assoc S Afr 1997 Nov;52(11):659-64. PMID: 9589004

Therapy

Lauritano D, Martinelli M, Baj A, Beltramini G, Candotto V, Ruggiero F, Palmieri A
Int J Immunopathol Pharmacol 2019 Jan-Dec;33:2058738419827746. doi: 10.1177/2058738419827746. PMID: 31663449Free PMC Article
Prescrire Int 2011 Dec;20(122):293-4. PMID: 22216543
Lafzi A, Farahani RM, Shoja MA
Med Oral Patol Oral Cir Bucal 2006 Nov 1;11(6):E480-2. PMID: 17072250
Hood KA
Prog Transplant 2002 Mar;12(1):17-21; quiz 22-3. doi: 10.1177/152692480201200104. PMID: 11993065
Varnfield M, Botha SJ
SADJ 2000 Nov;55(11):632-41. PMID: 12608228

Prognosis

Sonmez S, Cavdar C, Gunduz C, Nizam N, Biray C, Atila K, Camsari T
Transplant Proc 2008 Jan-Feb;40(1):181-3. doi: 10.1016/j.transproceed.2007.11.064. PMID: 18261580
Bolger WE, West CB Jr, Parsons DS, Gates GA
Int J Pediatr Otorhinolaryngol 1990 Mar;19(1):63-72. doi: 10.1016/0165-5876(90)90196-x. PMID: 2341235

Clinical prediction guides

Cune MS, Strooker H, van der Reijden WA, de Putter C, Laine ML, Verhoeven JW
Int J Oral Maxillofac Implants 2009 May-Jun;24(3):534-40. PMID: 19587878
Meisel P, Schwahn C, John U, Kroemer HK, Kocher T
Br J Clin Pharmacol 2005 Nov;60(5):552-9. doi: 10.1111/j.1365-2125.2005.02485.x. PMID: 16236046Free PMC Article
Saito K, Mori S, Tanda N, Sakamoto S
J Periodontol 1999 Jun;70(6):581-6. doi: 10.1902/jop.1999.70.6.581. PMID: 10397512
Saito K, Mori S, Iwakura M, Sakamoto S
J Periodontal Res 1996 Nov;31(8):545-55. doi: 10.1111/j.1600-0765.1996.tb00519.x. PMID: 8971653
Butler RT, Kalkwarf KL, Kaldahl WB
J Am Dent Assoc 1987 Jan;114(1):56-60. doi: 10.14219/jada.archive.1987.0050. PMID: 3468168

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