U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Thoracic myelocele

MedGen UID:
473137
•Concept ID:
C0431335
•
Congenital Abnormality
Synonym: Thoracic Myelocele
SNOMED CT: Thoracic myelocele (203991006)

Definition

Herniation of spinal cord tissue and meninges through a defect in the thoracic region of the vertebral column. The protrusion of the tissue is flush with the level of the skin surface. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThoracic myelocele

Professional guidelines

PubMed

Treatment of lumbar and intrathoracic meningocele: bioethical implications.
Tornali C, Pratico' A, Vecchio F, Polizzi A, Ruggieri M, Vecchio I
Acta Biomed 2021 Jul 1;92(3):e2021211. doi: 10.23750/abm.v92i3.11600. PMID: 34212901Free PMC Article
Myelomeningocele genotype-phenotype correlation findings in cilia, HH, PCP, and WNT signaling pathways.
Ortiz-Cruz G, Aguayo-Gómez A, Luna-Muñoz L, Muñoz-Téllez LA, Mutchinick OM
Birth Defects Res 2021 Mar;113(4):371-381. Epub 2021 Jan 19 doi: 10.1002/bdr2.1872. PMID: 33470056
Prenatal diagnosis and postnatal outcome of fetal spinal defects without Arnold-Chiari II malformation.
Hüsler MR, Danzer E, Johnson MP, Bebbington M, Sutton L, Adzick NS, Wilson RD
Prenat Diagn 2009 Nov;29(11):1050-7. doi: 10.1002/pd.2348. PMID: 19688779

Recent clinical studies

Etiology

Kyphectomy in myelomeningocele revisited: risk factors for failure.
Ghanem I, Saliba I, Ghanem D, Assi A, Dubousset J, Bernstein S, Tolo V, Bassett G, Miladi L
Eur Spine J 2023 Dec;32(12):4128-4144. Epub 2023 Sep 12 doi: 10.1007/s00586-023-07924-w. PMID: 37698696
Reviewing the prognostic factors in myelomeningocele.
Protzenko T, Bellas A, Pousa MS, Protzenko M, Fontes JM, de Lima Silveira AM, Sá CA, Pereira JP, Salomão RM, Salomão JFM, Dos Santos Gomes SC
Neurosurg Focus 2019 Oct 1;47(4):E2. doi: 10.3171/2019.7.FOCUS19462. PMID: 31574474
Iniencephaly.
Holmes LB, Toufaily MH, Westgate MN
Birth Defects Res 2018 Jan;110(2):128-133. doi: 10.1002/bdr2.1082. PMID: 29377645
Fractures in myelomeningocele.
Akbar M, Bresch B, Raiss P, Fürstenberg CH, Bruckner T, Seyler T, Carstens C, Abel R
J Orthop Traumatol 2010 Sep;11(3):175-82. Epub 2010 Aug 19 doi: 10.1007/s10195-010-0102-2. PMID: 20721596Free PMC Article
Myelomeningocele: neglected aspects.
Woodhouse CR
Pediatr Nephrol 2008 Aug;23(8):1223-31. Epub 2008 Jan 17 doi: 10.1007/s00467-007-0663-3. PMID: 18200450Free PMC Article

Diagnosis

Cervical myelomeningocele with CSF leakage: a case-based review.
Armas-Melián K, Iglesias S, Ros B, Martínez-León MI, Arráez MÁ
Childs Nerv Syst 2020 Nov;36(11):2615-2620. Epub 2020 Jul 4 doi: 10.1007/s00381-020-04743-y. PMID: 32621007
Reviewing the prognostic factors in myelomeningocele.
Protzenko T, Bellas A, Pousa MS, Protzenko M, Fontes JM, de Lima Silveira AM, Sá CA, Pereira JP, Salomão RM, Salomão JFM, Dos Santos Gomes SC
Neurosurg Focus 2019 Oct 1;47(4):E2. doi: 10.3171/2019.7.FOCUS19462. PMID: 31574474
Fetal myelomeningocele repair.
Yamashiro KJ, Galganski LA, Hirose S
Semin Pediatr Surg 2019 Aug;28(4):150823. Epub 2019 Jul 18 doi: 10.1053/j.sempedsurg.2019.07.006. PMID: 31451171
Fractures in myelomeningocele.
Akbar M, Bresch B, Raiss P, Fürstenberg CH, Bruckner T, Seyler T, Carstens C, Abel R
J Orthop Traumatol 2010 Sep;11(3):175-82. Epub 2010 Aug 19 doi: 10.1007/s10195-010-0102-2. PMID: 20721596Free PMC Article
Thoracic myelocystoceles--two variants.
Muthukumar N
Acta Neurochir (Wien) 2006 Jul;148(7):751-6; discussion 756. Epub 2006 Feb 9 doi: 10.1007/s00701-006-0734-4. PMID: 16467960

Therapy

Evolution and Variations of the Ovine Model of Spina Bifida.
Lee SY, Du Y, Hassan AS, Brown E, Saadai P, Hirose S, Wang A, Farmer DL
Fetal Diagn Ther 2023;50(6):491-500. Epub 2023 Jul 1 doi: 10.1159/000531750. PMID: 37393899Free PMC Article
Fetal Repair of Neural Tube Defects.
Lee SY, Papanna R, Farmer D, Tsao K
Clin Perinatol 2022 Dec;49(4):835-848. Epub 2022 Oct 9 doi: 10.1016/j.clp.2022.06.004. PMID: 36328602
Orthopaedic outcomes of prenatal versus postnatal repair of myelomeningocele.
Swarup I, Talwar D, Howell LJ, Adzick NS, Horn BD
J Pediatr Orthop B 2022 Jan 1;31(1):87-92. doi: 10.1097/BPB.0000000000000827. PMID: 33165214Free PMC Article
Reviewing the prognostic factors in myelomeningocele.
Protzenko T, Bellas A, Pousa MS, Protzenko M, Fontes JM, de Lima Silveira AM, Sá CA, Pereira JP, Salomão RM, Salomão JFM, Dos Santos Gomes SC
Neurosurg Focus 2019 Oct 1;47(4):E2. doi: 10.3171/2019.7.FOCUS19462. PMID: 31574474
Prenatal surgery for myelomeningocele: review of the literature and future directions.
Heuer GG, Moldenhauer JS, Scott Adzick N
Childs Nerv Syst 2017 Jul;33(7):1149-1155. Epub 2017 May 17 doi: 10.1007/s00381-017-3440-z. PMID: 28516217

Prognosis

Myelomeningocele in Slovenia: results of a 10-year follow-up.
Spazzapan P, Velnar T
J Neurosurg Sci 2021 Jun;65(3):369-376. Epub 2018 Sep 25 doi: 10.23736/S0390-5616.18.04481-8. PMID: 30259717
Reviewing the prognostic factors in myelomeningocele.
Protzenko T, Bellas A, Pousa MS, Protzenko M, Fontes JM, de Lima Silveira AM, Sá CA, Pereira JP, Salomão RM, Salomão JFM, Dos Santos Gomes SC
Neurosurg Focus 2019 Oct 1;47(4):E2. doi: 10.3171/2019.7.FOCUS19462. PMID: 31574474
Fractures in myelomeningocele.
Akbar M, Bresch B, Raiss P, Fürstenberg CH, Bruckner T, Seyler T, Carstens C, Abel R
J Orthop Traumatol 2010 Sep;11(3):175-82. Epub 2010 Aug 19 doi: 10.1007/s10195-010-0102-2. PMID: 20721596Free PMC Article
Surgical technique and outcome in cervical and thoracic myelomeningocoele surgery.
Etus V, Sarisoy HT, Ceylan S
J Clin Neurosci 2006 Jul;13(6):643-7; discussion 648. Epub 2006 Jun 23 doi: 10.1016/j.jocn.2005.06.016. PMID: 16797990
New technical advances in swivel walkers.
Stallard J, Lomas B, Woollam P, Farmer IR, Jones N, Poiner R, Miller K
Prosthet Orthot Int 2003 Aug;27(2):132-8. doi: 10.1080/03093640308726669. PMID: 14571943

Clinical prediction guides

Does Kyphectomy Improve the Quality of Life of Patients With Myelomeningocele?
Petersen PA, Marcon RM, Letaif OB, Mello Santos MA, Oliveira RG, Passos de Barros Filho TE, Cristante AF
Clin Orthop Relat Res 2020 Jan;478(1):104-111. doi: 10.1097/CORR.0000000000000976. PMID: 31567706Free PMC Article
Reviewing the prognostic factors in myelomeningocele.
Protzenko T, Bellas A, Pousa MS, Protzenko M, Fontes JM, de Lima Silveira AM, Sá CA, Pereira JP, Salomão RM, Salomão JFM, Dos Santos Gomes SC
Neurosurg Focus 2019 Oct 1;47(4):E2. doi: 10.3171/2019.7.FOCUS19462. PMID: 31574474
Hip Status and Long-term Functional Outcomes in Spina Bifida.
Thompson RM, Foley J, Dias L, Swaroop VT
J Pediatr Orthop 2019 Mar;39(3):e168-e172. doi: 10.1097/BPO.0000000000001266. PMID: 30300276
Evidence to inform decisions about maternal-fetal surgery: technical brief.
Hartmann KE, McPheeters ML, Chescheir NC, Gillam-Krakauer M, McKoy JN, Jerome R, Sathe NA, Meints L, Walsh WF
Obstet Gynecol 2011 May;117(5):1191-1204. doi: 10.1097/AOG.0b013e318216151d. PMID: 21471854
Fractures in myelomeningocele.
Akbar M, Bresch B, Raiss P, Fürstenberg CH, Bruckner T, Seyler T, Carstens C, Abel R
J Orthop Traumatol 2010 Sep;11(3):175-82. Epub 2010 Aug 19 doi: 10.1007/s10195-010-0102-2. PMID: 20721596Free PMC Article

Recent systematic reviews

Surgical limits, pitfalls, and potential solutions in kyphectomy in myelomeningocele: three cases and systematic review of the literature.
De Marco R, Nasto LA, Strangio A, Piatelli G, Pavanello M
Childs Nerv Syst 2024 May;40(5):1541-1569. Epub 2024 Mar 9 doi: 10.1007/s00381-024-06341-8. PMID: 38459148

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...