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Chronic bullous dermatosis of childhood

MedGen UID:
473184
•Concept ID:
C0494827
•
Disease or Syndrome
Synonym: Chronic Bullous Disease of Childhood
SNOMED CT: Childhood linear IgA disease (109250009); Benign chronic bullous dermatosis of childhood (109250009); Chronic bullous dermatosis of childhood (109250009); Linear IgA bullous disease in children (109250009)

Definition

A blistering disorder characterized by linear deposition of IgA at the dermoepidermal junction. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic bullous dermatosis of childhood

Professional guidelines

PubMed

The treatment of benign chronic bullous dermatosis of childhood, and dermatitis herpetiformis and bullous pemphigoid beginning in childhood.
Marsden RA
Clin Exp Dermatol 1982 Nov;7(6):653-63. doi: 10.1111/j.1365-2230.1982.tb02491.x. PMID: 6758997

Recent clinical studies

Etiology

Clinical features of chronic bullous dermatosis of childhood.
Wilson A, Murrell DF
Clin Exp Dermatol 2022 May;47(5):873-881. Epub 2022 Jan 2 doi: 10.1111/ced.15059. PMID: 34919291
Linear IgA Bullous Dermatosis: A Series of 17 Cases.
Díaz MS, Morita L, Ferrari B, Sartori S, Greco MF, Sobrevias Bonells L, González-Enseñat MA, Vicente Villa MA, Larralde M
Actas Dermosifiliogr (Engl Ed) 2019 Oct;110(8):673-680. Epub 2019 Apr 20 doi: 10.1016/j.ad.2018.06.017. PMID: 31014539
Chronic Bullous Dermatosis of Childhood and the String of Pearls Sign.
Tate C, Christian W, Newell L
J Pediatr 2018 Nov;202:325-325.e1. Epub 2018 Aug 29 doi: 10.1016/j.jpeds.2018.07.070. PMID: 30172440
Colchicine as a novel therapeutic agent in chronic bullous dermatosis of childhood.
Banodkar DD, al-Suwaid AR
Int J Dermatol 1997 Mar;36(3):213-6. doi: 10.1046/j.1365-4362.1997.00033.x. PMID: 9159009
Chronic bullous dermatosis of childhood--clinical and immunological features seen in African patients.
Aboobaker J, Wojnarowska FT, Bhogal B, Black MM
Clin Exp Dermatol 1991 May;16(3):160-4. doi: 10.1111/j.1365-2230.1991.tb00336.x. PMID: 1934564

Diagnosis

Clinical features of chronic bullous dermatosis of childhood.
Wilson A, Murrell DF
Clin Exp Dermatol 2022 May;47(5):873-881. Epub 2022 Jan 2 doi: 10.1111/ced.15059. PMID: 34919291
Linear IgA Bullous Dermatosis: A Series of 17 Cases.
Díaz MS, Morita L, Ferrari B, Sartori S, Greco MF, Sobrevias Bonells L, González-Enseñat MA, Vicente Villa MA, Larralde M
Actas Dermosifiliogr (Engl Ed) 2019 Oct;110(8):673-680. Epub 2019 Apr 20 doi: 10.1016/j.ad.2018.06.017. PMID: 31014539
Linear IgA bullous dermatosis of childhood (chronic bullous dermatosis of childhood).
Jabłońska S, Chorzelski TP, Rosinska D, Maciejowska E
Clin Dermatol 1991 Jul-Sep;9(3):393-401. doi: 10.1016/0738-081x(91)90031-f. PMID: 1806227
Chronic bullous dermatosis of childhood.
Tomecki KJ
South Med J 1983 May;76(5):651-3. doi: 10.1097/00007611-198305000-00030. PMID: 6342155
Chronic bullous dermatosis of childhood.
Esterly NB, Furey NL, Kirschner BS, Kretschmer RR, Septon RM
Arch Dermatol 1977 Jan;113(1):42-6. PMID: 318816

Therapy

Linear IgA Bullous Dermatosis: A Series of 17 Cases.
Díaz MS, Morita L, Ferrari B, Sartori S, Greco MF, Sobrevias Bonells L, González-Enseñat MA, Vicente Villa MA, Larralde M
Actas Dermosifiliogr (Engl Ed) 2019 Oct;110(8):673-680. Epub 2019 Apr 20 doi: 10.1016/j.ad.2018.06.017. PMID: 31014539
Chronic Bullous Dermatosis of Childhood and the String of Pearls Sign.
Tate C, Christian W, Newell L
J Pediatr 2018 Nov;202:325-325.e1. Epub 2018 Aug 29 doi: 10.1016/j.jpeds.2018.07.070. PMID: 30172440
Linear IgA bullous dermatosis of childhood (chronic bullous dermatosis of childhood).
Jabłońska S, Chorzelski TP, Rosinska D, Maciejowska E
Clin Dermatol 1991 Jul-Sep;9(3):393-401. doi: 10.1016/0738-081x(91)90031-f. PMID: 1806227
Chronic bullous dermatosis of childhood.
Tomecki KJ
South Med J 1983 May;76(5):651-3. doi: 10.1097/00007611-198305000-00030. PMID: 6342155
Chronic bullous dermatosis of childhood.
Esterly NB, Furey NL, Kirschner BS, Kretschmer RR, Septon RM
Arch Dermatol 1977 Jan;113(1):42-6. PMID: 318816

Prognosis

Chronic bullous dermatosis of childhood: relapse after puberty.
Hamann ID, Hepburn NC, Hunter JA
J R Soc Med 1995 May;88(5):296P-297P. PMID: 7636830Free PMC Article
Chronic bullous dermatosis of childhood--clinical and immunological features seen in African patients.
Aboobaker J, Wojnarowska FT, Bhogal B, Black MM
Clin Exp Dermatol 1991 May;16(3):160-4. doi: 10.1111/j.1365-2230.1991.tb00336.x. PMID: 1934564
Chronic bullous dermatosis of childhood persisting into adulthood.
Burge S, Wojnarowska F, Marsden A
Pediatr Dermatol 1988 Nov;5(4):246-9. doi: 10.1111/j.1525-1470.1988.tb00896.x. PMID: 3068653
Chronic bullous dermatosis of childhood.
Kárpáti S, Török E, Vajda Z, Répay I, Kósnai I
Acta Paediatr Acad Sci Hung 1981;22(4):331-9. PMID: 7044025

Clinical prediction guides

Linear IgA Bullous Dermatosis: A Series of 17 Cases.
Díaz MS, Morita L, Ferrari B, Sartori S, Greco MF, Sobrevias Bonells L, González-Enseñat MA, Vicente Villa MA, Larralde M
Actas Dermosifiliogr (Engl Ed) 2019 Oct;110(8):673-680. Epub 2019 Apr 20 doi: 10.1016/j.ad.2018.06.017. PMID: 31014539
Colchicine as a novel therapeutic agent in chronic bullous dermatosis of childhood.
Banodkar DD, al-Suwaid AR
Int J Dermatol 1997 Mar;36(3):213-6. doi: 10.1046/j.1365-4362.1997.00033.x. PMID: 9159009
Distribution of the antigen in adult linear IgA disease and chronic bullous dermatosis of childhood suggests that it is a single and unique antigen.
Pothupitiya GM, Wojnarowska F, Bhogal BS, Black MM
Br J Dermatol 1988 Feb;118(2):175-82. doi: 10.1111/j.1365-2133.1988.tb01771.x. PMID: 2831930
Juvenile dermatitis herpetiformis.
Diaz LA, Lamkin BC, Dubin HV
Arch Dermatol 1979 May;115(5):584-6. PMID: 375840

Recent systematic reviews

Clinical features of chronic bullous dermatosis of childhood.
Wilson A, Murrell DF
Clin Exp Dermatol 2022 May;47(5):873-881. Epub 2022 Jan 2 doi: 10.1111/ced.15059. PMID: 34919291

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