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Retinopathy of prematurity stage 1

MedGen UID:
473427
Concept ID:
C1443381
Disease or Syndrome
Synonyms: Retinopathy of prematurity stage 1 - demarcation line; Retinopathy of Prematurity Stage 1 Demarcation Line; ROP stage 1
SNOMED CT: Retinopathy of prematurity stage 1 - demarcation line (408847006)
 
HPO: HP:0500050

Definition

The retinal vessels stop and then a linear flat white line is present that usually runs the circumference of the vascular retina. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRetinopathy of prematurity stage 1

Professional guidelines

PubMed

Solans Pérez de Larraya AM, Ortega Molina JM, Fernández JU, Escudero Gómez J, Salgado Miranda AD, Chaves Samaniego MJ, García Serrano JL
Eur J Ophthalmol 2018 Jul;28(4):441-445. Epub 2018 Mar 27 doi: 10.1177/1120672118761328. PMID: 29587487

Recent clinical studies

Etiology

Ge G, Zhang Y, Zhang M
Acta Ophthalmol 2021 Dec;99(8):e1263-e1273. Epub 2021 Feb 21 doi: 10.1111/aos.14827. PMID: 33611839
Wang X, Tang K, Chen L, Cheng S, Xu H
BMJ Open 2019 May 24;9(5):e025440. doi: 10.1136/bmjopen-2018-025440. PMID: 31129577Free PMC Article
Edy Siswanto J, Sauer PJ
J Neonatal Perinatal Med 2017;10(1):85-90. doi: 10.3233/NPM-915142. PMID: 28304327
Chawla D, Agarwal R, Deorari A, Paul VK, Chandra P, Azad RV
Indian J Pediatr 2012 Apr;79(4):501-9. Epub 2010 Oct 27 doi: 10.1007/s12098-010-0279-7. PMID: 20978871
Ben Sira I, Nissenkorn I, Kremer I
Surv Ophthalmol 1988 Jul-Aug;33(1):1-16. doi: 10.1016/0039-6257(88)90068-9. PMID: 3051465

Diagnosis

Dumbrăveanu L, Cușnir V, Bobescu D
Rom J Ophthalmol 2021 Oct-Dec;65(4):315-329. doi: 10.22336/rjo.2021.66. PMID: 35087972Free PMC Article
Chiang MF, Quinn GE, Fielder AR, Ostmo SR, Paul Chan RV, Berrocal A, Binenbaum G, Blair M, Peter Campbell J, Capone A Jr, Chen Y, Dai S, Ells A, Fleck BW, Good WV, Elizabeth Hartnett M, Holmstrom G, Kusaka S, Kychenthal A, Lepore D, Lorenz B, Martinez-Castellanos MA, Özdek Ş, Ademola-Popoola D, Reynolds JD, Shah PK, Shapiro M, Stahl A, Toth C, Vinekar A, Visser L, Wallace DK, Wu WC, Zhao P, Zin A
Ophthalmology 2021 Oct;128(10):e51-e68. Epub 2021 Jul 8 doi: 10.1016/j.ophtha.2021.05.031. PMID: 34247850Free PMC Article
Hellström A, Nilsson AK, Wackernagel D, Pivodic A, Vanpee M, Sjöbom U, Hellgren G, Hallberg B, Domellöf M, Klevebro S, Hellström W, Andersson M, Lund AM, Löfqvist C, Elfvin A, Sävman K, Hansen-Pupp I, Hård AL, Smith LEH, Ley D
JAMA Pediatr 2021 Apr 1;175(4):359-367. doi: 10.1001/jamapediatrics.2020.5653. PMID: 33523106Free PMC Article
Keskinbora K, Güven F
Turk J Ophthalmol 2020 Mar 5;50(1):37-43. doi: 10.4274/tjo.galenos.2020.78989. PMID: 32167262Free PMC Article
Wang X, Tang K, Chen L, Cheng S, Xu H
BMJ Open 2019 May 24;9(5):e025440. doi: 10.1136/bmjopen-2018-025440. PMID: 31129577Free PMC Article

Therapy

Stahl A, Sukgen EA, Wu WC, Lepore D, Nakanishi H, Mazela J, Moshfeghi DM, Vitti R, Athanikar A, Chu K, Iveli P, Zhao F, Schmelter T, Leal S, Köfüncü E, Azuma N; FIREFLEYE Study Group
JAMA 2022 Jul 26;328(4):348-359. doi: 10.1001/jama.2022.10564. PMID: 35881122Free PMC Article
Bancalari A, Schade R
Am J Perinatol 2022 Jan;39(1):22-30. Epub 2020 Jun 16 doi: 10.1055/s-0040-1713181. PMID: 32544962
Dumbrăveanu L, Cușnir V, Bobescu D
Rom J Ophthalmol 2021 Oct-Dec;65(4):315-329. doi: 10.22336/rjo.2021.66. PMID: 35087972Free PMC Article
Hellström A, Nilsson AK, Wackernagel D, Pivodic A, Vanpee M, Sjöbom U, Hellgren G, Hallberg B, Domellöf M, Klevebro S, Hellström W, Andersson M, Lund AM, Löfqvist C, Elfvin A, Sävman K, Hansen-Pupp I, Hård AL, Smith LEH, Ley D
JAMA Pediatr 2021 Apr 1;175(4):359-367. doi: 10.1001/jamapediatrics.2020.5653. PMID: 33523106Free PMC Article
Chawla D, Agarwal R, Deorari A, Paul VK, Chandra P, Azad RV
Indian J Pediatr 2012 Apr;79(4):501-9. Epub 2010 Oct 27 doi: 10.1007/s12098-010-0279-7. PMID: 20978871

Prognosis

Dumbrăveanu L, Cușnir V, Bobescu D
Rom J Ophthalmol 2021 Oct-Dec;65(4):315-329. doi: 10.22336/rjo.2021.66. PMID: 35087972Free PMC Article
Cao Y, Jiang S, Sun J, Hei M, Wang L, Zhang H, Ma X, Wu H, Li X, Sun H, Zhou W, Shi Y, Wang Y, Gu X, Yang T, Lu Y, Du L, Chen C, Lee SK, Zhou W; Chinese Neonatal Network
JAMA Netw Open 2021 Aug 2;4(8):e2118904. doi: 10.1001/jamanetworkopen.2021.18904. PMID: 34338792Free PMC Article
Ge G, Zhang Y, Zhang M
Acta Ophthalmol 2021 Dec;99(8):e1263-e1273. Epub 2021 Feb 21 doi: 10.1111/aos.14827. PMID: 33611839
Ancel PY, Goffinet F; EPIPAGE-2 Writing Group, Kuhn P, Langer B, Matis J, Hernandorena X, Chabanier P, Joly-Pedespan L, Lecomte B, Vendittelli F, Dreyfus M, Guillois B, Burguet A, Sagot P, Sizun J, Beuchée A, Rouget F, Favreau A, Saliba E, Bednarek N, Morville P, Thiriez G, Marpeau L, Marret S, Kayem G, Durrmeyer X, Granier M, Baud O, Jarreau PH, Mitanchez D, Boileau P, Boulot P, Cambonie G, Daudé H, Bédu A, Mons F, Fresson J, Vieux R, Alberge C, Arnaud C, Vayssière C, Truffert P, Pierrat V, Subtil D, D'Ercole C, Gire C, Simeoni U, Bongain A, Sentilhes L, Rozé JC, Gondry J, Leke A, Deiber M, Claris O, Picaud JC, Ego A, Debillon T, Poulichet A, Coliné E, Favre A, Fléchelles O, Samperiz S, Ramful D, Branger B, Benhammou V, Foix-L'Hélias L, Marchand-Martin L, Kaminski M
JAMA Pediatr 2015 Mar;169(3):230-8. doi: 10.1001/jamapediatrics.2014.3351. PMID: 25621457
Chawla D, Agarwal R, Deorari A, Paul VK, Chandra P, Azad RV
Indian J Pediatr 2012 Apr;79(4):501-9. Epub 2010 Oct 27 doi: 10.1007/s12098-010-0279-7. PMID: 20978871

Clinical prediction guides

Ling XC, Kang EY, Chen KJ, Wang NK, Liu L, Chen YP, Hwang YS, Lai CC, Yang SF, Wu WC
Invest Ophthalmol Vis Sci 2023 Jun 1;64(7):11. doi: 10.1167/iovs.64.7.11. PMID: 37272765Free PMC Article
Young BK, Cole ED, Shah PK, Ostmo S, Subramaniam P, Venkatapathy N, Tsai ASH, Coyner AS, Gupta A, Singh P, Chiang MF, Kalpathy-Cramer J, Chan RVP, Campbell JP
JAMA Ophthalmol 2023 Jun 1;141(6):582-588. doi: 10.1001/jamaophthalmol.2023.1466. PMID: 37166816Free PMC Article
Gao L, Shao W, Li N, Tian C, Jia H, Peng X, Shi Q
Biomed Res Int 2019;2019:2095730. Epub 2019 Jul 11 doi: 10.1155/2019/2095730. PMID: 31380413Free PMC Article
Wang X, Tang K, Chen L, Cheng S, Xu H
BMJ Open 2019 May 24;9(5):e025440. doi: 10.1136/bmjopen-2018-025440. PMID: 31129577Free PMC Article
Chawla D, Agarwal R, Deorari A, Paul VK, Chandra P, Azad RV
Indian J Pediatr 2012 Apr;79(4):501-9. Epub 2010 Oct 27 doi: 10.1007/s12098-010-0279-7. PMID: 20978871

Recent systematic reviews

Huang J, Tang Y, Zhu T, Li Y, Chun H, Qu Y, Mu D
Medicine (Baltimore) 2019 Oct;98(42):e17512. doi: 10.1097/MD.0000000000017512. PMID: 31626109Free PMC Article
Wang X, Tang K, Chen L, Cheng S, Xu H
BMJ Open 2019 May 24;9(5):e025440. doi: 10.1136/bmjopen-2018-025440. PMID: 31129577Free PMC Article
Azami M, Jaafari Z, Rahmati S, Farahani AD, Badfar G
BMC Ophthalmol 2018 Apr 2;18(1):83. doi: 10.1186/s12886-018-0732-3. PMID: 29606108Free PMC Article
Kaempfen S, Neumann RP, Jost K, Schulzke SM
Cochrane Database Syst Rev 2018 Mar 2;3(3):CD011893. doi: 10.1002/14651858.CD011893.pub2. PMID: 29499081Free PMC Article
Zhu T, Zhang L, Zhao F, Qu Y, Mu D
PLoS One 2017;12(4):e0175374. Epub 2017 Apr 7 doi: 10.1371/journal.pone.0175374. PMID: 28388642Free PMC Article

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