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Extrahepatic Bile Duct Adenocarcinoma, Intestinal Type

MedGen UID:
473529
Concept ID:
C2064429
Neoplastic Process

Definition

An adenocarcinoma that arises from the extrahepatic bile ducts. It is characterized by the presence of neoplastic tubular glands lined by columnar cells or neoplastic glands lined by goblet cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVExtrahepatic Bile Duct Adenocarcinoma, Intestinal Type

Professional guidelines

PubMed

Patel M, Uboha NV
Curr Treat Options Oncol 2021 Sep 29;22(11):103. doi: 10.1007/s11864-021-00894-5. PMID: 34586537
Kunovský L, Kala Z, Procházka V, Potrusil M, Dastych M, Novotný I, Andrasina T, Pavlovský Z, Eid M, Moravcik P
Klin Onkol 2017 Winter;31(1):46-52. doi: 10.14735/amko201846. PMID: 29488778
Juliusson G, Jonasson JG, Jonsdottir SB, Garcia HG, Olafsdottir E, Möller PH, Björnsson ES
Scand J Gastroenterol 2016 Dec;51(12):1520-1525. Epub 2016 Aug 24 doi: 10.1080/00365521.2016.1218538. PMID: 27553174

Recent clinical studies

Etiology

Jackson SS, Pfeiffer RM, Gabbi C, Anderson L, Gadalla SM, Koshiol J
Hepatology 2022 Feb;75(2):309-321. doi: 10.1002/hep.32198. PMID: 34766362Free PMC Article
Kunovský L, Kala Z, Procházka V, Potrusil M, Dastych M, Novotný I, Andrasina T, Pavlovský Z, Eid M, Moravcik P
Klin Onkol 2017 Winter;31(1):46-52. doi: 10.14735/amko201846. PMID: 29488778
Neoptolemos JP, Moore MJ, Cox TF, Valle JW, Palmer DH, McDonald AC, Carter R, Tebbutt NC, Dervenis C, Smith D, Glimelius B, Charnley RM, Lacaine F, Scarfe AG, Middleton MR, Anthoney A, Ghaneh P, Halloran CM, Lerch MM, Oláh A, Rawcliffe CL, Verbeke CS, Campbell F, Büchler MW; European Study Group for Pancreatic Cancer
JAMA 2012 Jul 11;308(2):147-56. doi: 10.1001/jama.2012.7352. PMID: 22782416
Westgaard A, Clausen OP, Gladhaug IP
APMIS 2011 Oct;119(10):689-700. Epub 2011 Jun 15 doi: 10.1111/j.1600-0463.2011.02783.x. PMID: 21917006
Heinrich S, Clavien PA
Curr Opin Gastroenterol 2010 May;26(3):280-5. doi: 10.1097/MOG.0b013e3283378eb0. PMID: 20168227

Diagnosis

Jackson SS, Pfeiffer RM, Gabbi C, Anderson L, Gadalla SM, Koshiol J
Hepatology 2022 Feb;75(2):309-321. doi: 10.1002/hep.32198. PMID: 34766362Free PMC Article
Tsai YE, Chien KH, Li YF, Lai SW
Medicina (Kaunas) 2021 Nov 12;57(11) doi: 10.3390/medicina57111238. PMID: 34833456Free PMC Article
Patel M, Uboha NV
Curr Treat Options Oncol 2021 Sep 29;22(11):103. doi: 10.1007/s11864-021-00894-5. PMID: 34586537
Kleinert R, Prenzel K, Stoecklein N, Alakus H, Bollschweiler E, Hölscher A, Warnecke-Eberz U
Anticancer Res 2015 Nov;35(11):6153-8. PMID: 26504042
Williamson JM, Thorn CC, Spalding D, Williamson RC
Ann R Coll Surg Engl 2011 Jul;93(5):356-60. doi: 10.1308/003588411X582681. PMID: 21943457Free PMC Article

Therapy

Patel M, Uboha NV
Curr Treat Options Oncol 2021 Sep 29;22(11):103. doi: 10.1007/s11864-021-00894-5. PMID: 34586537
Elebro J, Ben Dror L, Heby M, Nodin B, Jirström K, Eberhard J
Acta Oncol 2016;55(3):286-96. Epub 2015 Sep 11 doi: 10.3109/0284186X.2015.1075663. PMID: 26362587Free PMC Article
Senatore FJ, Ynson ML, Dasanu CA
J Oncol Pharm Pract 2015 Oct;21(5):364-9. Epub 2014 Jun 5 doi: 10.1177/1078155214538086. PMID: 24906539
Neoptolemos JP, Moore MJ, Cox TF, Valle JW, Palmer DH, McDonald AC, Carter R, Tebbutt NC, Dervenis C, Smith D, Glimelius B, Charnley RM, Lacaine F, Scarfe AG, Middleton MR, Anthoney A, Ghaneh P, Halloran CM, Lerch MM, Oláh A, Rawcliffe CL, Verbeke CS, Campbell F, Büchler MW; European Study Group for Pancreatic Cancer
JAMA 2012 Jul 11;308(2):147-56. doi: 10.1001/jama.2012.7352. PMID: 22782416
Heinrich S, Clavien PA
Curr Opin Gastroenterol 2010 May;26(3):280-5. doi: 10.1097/MOG.0b013e3283378eb0. PMID: 20168227

Prognosis

Jackson SS, Pfeiffer RM, Gabbi C, Anderson L, Gadalla SM, Koshiol J
Hepatology 2022 Feb;75(2):309-321. doi: 10.1002/hep.32198. PMID: 34766362Free PMC Article
Patel M, Uboha NV
Curr Treat Options Oncol 2021 Sep 29;22(11):103. doi: 10.1007/s11864-021-00894-5. PMID: 34586537
Perysinakis I, Margaris I, Kouraklis G
Histopathology 2014 May;64(6):759-68. Epub 2014 Jan 24 doi: 10.1111/his.12324. PMID: 24456259
Neoptolemos JP, Moore MJ, Cox TF, Valle JW, Palmer DH, McDonald AC, Carter R, Tebbutt NC, Dervenis C, Smith D, Glimelius B, Charnley RM, Lacaine F, Scarfe AG, Middleton MR, Anthoney A, Ghaneh P, Halloran CM, Lerch MM, Oláh A, Rawcliffe CL, Verbeke CS, Campbell F, Büchler MW; European Study Group for Pancreatic Cancer
JAMA 2012 Jul 11;308(2):147-56. doi: 10.1001/jama.2012.7352. PMID: 22782416
Yonezawa S, Higashi M, Yamada N, Yokoyama S, Goto M
J Hepatobiliary Pancreat Sci 2010 Mar;17(2):108-24. Epub 2009 Sep 29 doi: 10.1007/s00534-009-0174-7. PMID: 19787286

Clinical prediction guides

Xia M, Overman MJ, Rashid A, Chatterjee D, Wang H, Katz MH, Fleming JB, Lee JE, Varadhachary GR, Wolff RA, Wang H
Hum Pathol 2015 Sep;46(9):1315-22. Epub 2015 May 30 doi: 10.1016/j.humpath.2015.05.012. PMID: 26165226
Valsangkar NP, Ingkakul T, Correa-Gallego C, Mino-Kenudson M, Masia R, Lillemoe KD, Fernández-del Castillo C, Warshaw AL, Liss AS, Thayer SP
Surgery 2015 Feb;157(2):260-8. doi: 10.1016/j.surg.2014.08.092. PMID: 25616942Free PMC Article
Neoptolemos JP, Moore MJ, Cox TF, Valle JW, Palmer DH, McDonald AC, Carter R, Tebbutt NC, Dervenis C, Smith D, Glimelius B, Charnley RM, Lacaine F, Scarfe AG, Middleton MR, Anthoney A, Ghaneh P, Halloran CM, Lerch MM, Oláh A, Rawcliffe CL, Verbeke CS, Campbell F, Büchler MW; European Study Group for Pancreatic Cancer
JAMA 2012 Jul 11;308(2):147-56. doi: 10.1001/jama.2012.7352. PMID: 22782416
Yonezawa S, Higashi M, Yamada N, Yokoyama S, Goto M
J Hepatobiliary Pancreat Sci 2010 Mar;17(2):108-24. Epub 2009 Sep 29 doi: 10.1007/s00534-009-0174-7. PMID: 19787286
Filiz G, Yerci O, Adim SB, Gurel S, Dolar E, Memik F
Hepatogastroenterology 2007 Jun;54(76):1247-9. PMID: 17629080

Recent systematic reviews

Uijterwijk BA, Lemmers DH, Fusai GK, Zerbi A, Salvia R, Sparrelid E, White S, Björnsson B, Mavroeidis VK, Roberts KJ, Mazzola M, Cabús SS, Soonawalla Z, Korkolis D, Serradilla M, Pessaux P, Luyer M, Mowbray N, Ielpo B, Mazzotta A, Kleeff J, Boggi U, Muñoz MAS, Goh BKP, Andreotti E, Wilmink H, Ghidini M, Zaniboni A, Verbeke C, Adsay V, Bianchi D, Besselink MG, Abu Hilal M; International Study Group on Non-Pancreatic Periampullary Cancer (ISGACA)
Ann Surg Oncol 2024 Jul;31(7):4654-4664. Epub 2024 Apr 11 doi: 10.1245/s10434-024-15213-z. PMID: 38602578Free PMC Article

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