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Extrahepatic bile duct sarcoma

MedGen UID:
473546
•Concept ID:
C2205442
•
Neoplastic Process
Synonyms: Extrahepatic Bile Duct Sarcoma; extrahepatic bile duct sarcoma; Sarcoma of Extrahepatic Bile Duct; sarcoma of extrahepatic bile duct; Sarcoma of the Extrahepatic Bile Duct; sarcoma of the extrahepatic bile duct
 
Monarch Initiative: MONDO:0024658

Definition

A malignant soft tissue neoplasm that arises from the extrahepatic bile ducts. Representative examples include Kaposi sarcoma, leiomyosarcoma, and rhabdomyosarcoma. [from NCI]

Professional guidelines

PubMed

Treatment options for other hepatic malignancies.
O'Grady JG
Liver Transpl 2000 Nov;6(6 Suppl 2):S23-9. doi: 10.1053/jlts.2000.18687. PMID: 11084081
Protocol for the examination of specimens from patients with carcinomas of the extrahepatic bile ducts, exclusive of sarcomas and carcinoid tumors: a basis for checklists. Cancer Committee of the College of American Pathologists.
Henson DE, Albores-Saavedra J, Compton CC
Arch Pathol Lab Med 2000 Jan;124(1):26-9. doi: 10.5858/2000-124-0026-PFTEOS. PMID: 10629127
Management of carcinoma of the extrahepatic bile ducts.
Black K, Hanna SS, Langer B, Jirsch DW, Rider WD
Can J Surg 1978 Nov;21(6):542-5. PMID: 83901

Recent clinical studies

Etiology

Optimizing Patient Pathways in Advanced Biliary Tract Cancers: Recent Advances and a French Perspective.
Neuzillet C, Artru P, Assenat E, Edeline J, Adhoute X, Sabourin JC, Turpin A, Coriat R, Malka D
Target Oncol 2023 Jan;18(1):51-76. Epub 2023 Feb 6 doi: 10.1007/s11523-022-00942-6. PMID: 36745342Free PMC Article
From Krukenberg to today: the ever present problems posed by metastatic tumors in the ovary. Part II.
Young RH
Adv Anat Pathol 2007 May;14(3):149-77. doi: 10.1097/PAP.0b013e3180504abf. PMID: 17452813
Transduodenal excision of tumours of the ampulla of Vater.
Alstrup N, Burcharth F, Hauge C, Horn T
Eur J Surg 1996 Dec;162(12):961-7. PMID: 9001878
Experience with 647 consecutive tumors of the duodenum, ampulla, head of the pancreas, and distal common bile duct.
Michelassi F, Erroi F, Dawson PJ, Pietrabissa A, Noda S, Handcock M, Block GE
Ann Surg 1989 Oct;210(4):544-54; discussion 554-6. doi: 10.1097/00000658-198910000-00015. PMID: 2679459Free PMC Article
Pancreaticogastrostomy following pancreatoduodenectomy.
Icard P, Dubois F
Ann Surg 1988 Mar;207(3):253-6. doi: 10.1097/00000658-198803000-00005. PMID: 3345112Free PMC Article

Diagnosis

Optimizing Patient Pathways in Advanced Biliary Tract Cancers: Recent Advances and a French Perspective.
Neuzillet C, Artru P, Assenat E, Edeline J, Adhoute X, Sabourin JC, Turpin A, Coriat R, Malka D
Target Oncol 2023 Jan;18(1):51-76. Epub 2023 Feb 6 doi: 10.1007/s11523-022-00942-6. PMID: 36745342Free PMC Article
Postradiation Synovial Sarcoma of the Common Bile Duct: A Previously Unreported Anatomic Site.
Herrera-Goepfert R
Int J Surg Pathol 2018 Aug;26(5):469-474. Epub 2018 Jan 16 doi: 10.1177/1066896917752863. PMID: 29336183
Histiocytic sarcoma of the bile duct.
Miyabe K, Masaki A, Nakazawa T, Ando T, Hayashi K, Naitoh I, Okumura F, Shimizu S, Kondo H, Yoshida M, Yamashita H, Umemura S, Hori Y, Ge Y, Ohara H, Joh T, Inagaki H
Intern Med 2014;53(7):707-12. Epub 2012 Mar 1 doi: 10.2169/internalmedicine.53.1384. PMID: 24694481
Undifferentiated carcinoma of the common bile duct: case report and review of the literature.
Nagai E, Shinohara M, Yonemasu H, Kishikawa H, Tsuneyoshi M
J Hepatobiliary Pancreat Surg 2002;9(5):627-31. doi: 10.1007/s005340200085. PMID: 12541051
Experience with 647 consecutive tumors of the duodenum, ampulla, head of the pancreas, and distal common bile duct.
Michelassi F, Erroi F, Dawson PJ, Pietrabissa A, Noda S, Handcock M, Block GE
Ann Surg 1989 Oct;210(4):544-54; discussion 554-6. doi: 10.1097/00000658-198910000-00015. PMID: 2679459Free PMC Article

Therapy

Optimizing Patient Pathways in Advanced Biliary Tract Cancers: Recent Advances and a French Perspective.
Neuzillet C, Artru P, Assenat E, Edeline J, Adhoute X, Sabourin JC, Turpin A, Coriat R, Malka D
Target Oncol 2023 Jan;18(1):51-76. Epub 2023 Feb 6 doi: 10.1007/s11523-022-00942-6. PMID: 36745342Free PMC Article
Mesenchymal chondrosarcoma metastasising to the pancreas.
Paasch C, De Santo G, Boettge KR, Strik MW
BMJ Case Rep 2018 Dec 31;11(1) doi: 10.1136/bcr-2018-226369. PMID: 30598468Free PMC Article
Prolonged survival of a patient affected by pancreatic adenocarcinoma with massive lymphocyte and dendritic cell infiltration after interleukin-2 immunotherapy. Report of a case.
Nobili C, Degrate L, Caprotti R, Franciosi C, Leone BE, Trezzi R, Romano F, Uggeri F, Uggeri F
Tumori 2008 May-Jun;94(3):426-30. doi: 10.1177/030089160809400323. PMID: 18705415
Analysis of human common bile duct-associated T cells: evidence for oligoclonality, T cell clonal persistence, and epithelial cell recognition.
Probert CS, Christ AD, Saubermann LJ, Turner JR, Chott A, Carr-Locke D, Balk SP, Blumberg RS
J Immunol 1997 Feb 15;158(4):1941-8. PMID: 9029136
Orthotopic liver transplantation in primary liver tumors.
Moreno-González E, Loinaz C, Gómez R, Garciá I, González-Pinto I, Jiménez C, Maffettone V, Colina F, Palomo JC, Vorwald P, Musella M
J Surg Oncol Suppl 1993;3:74-7. doi: 10.1002/jso.2930530521. PMID: 8389177

Prognosis

Obstructive Jaundice with skin involvement - An unusual presentation of Myeloid Sarcoma.
Jeji PS, Patnaik SK, Behera MK, Narayan J, Sahu MK, Mishra D, Singh A, Pati GK
Indian J Pathol Microbiol 2023 Oct-Dec;66(4):862-864. doi: 10.4103/ijpm.ijpm_1108_21. PMID: 38084550
Optimizing Patient Pathways in Advanced Biliary Tract Cancers: Recent Advances and a French Perspective.
Neuzillet C, Artru P, Assenat E, Edeline J, Adhoute X, Sabourin JC, Turpin A, Coriat R, Malka D
Target Oncol 2023 Jan;18(1):51-76. Epub 2023 Feb 6 doi: 10.1007/s11523-022-00942-6. PMID: 36745342Free PMC Article
Carcinosarcoma of the Extrahepatic Bile Duct Presenting with Stone-like Radiological Findings.
Kumei S, Onishi Y, Ogura T, Kusumoto C, Matsuno Y, Nishigami T, Maeda M, Harada M
Intern Med 2015;54(14):1747-51. Epub 2015 Jul 15 doi: 10.2169/internalmedicine.54.3082. PMID: 26179529
Experience with 647 consecutive tumors of the duodenum, ampulla, head of the pancreas, and distal common bile duct.
Michelassi F, Erroi F, Dawson PJ, Pietrabissa A, Noda S, Handcock M, Block GE
Ann Surg 1989 Oct;210(4):544-54; discussion 554-6. doi: 10.1097/00000658-198910000-00015. PMID: 2679459Free PMC Article
Pancreaticogastrostomy following pancreatoduodenectomy.
Icard P, Dubois F
Ann Surg 1988 Mar;207(3):253-6. doi: 10.1097/00000658-198803000-00005. PMID: 3345112Free PMC Article

Clinical prediction guides

First report on establishment and characterization of the extrahepatic cholangiocarcinoma sarcoma cell line CBC2T-2.
Jiang NZ, Bai MZ, Huang CF, Ma ZL, Zhong RY, Fu WK, Gao L, Tian L, Mi NN, Ma HD, Lu YW, Zhang ZA, Zhao JY, Yu HY, Zhang BP, Zhang XZ, Ren YX, Zhang C, Zhang Y, Yue P, Lin YY, Meng WB
World J Gastroenterol 2023 Nov 7;29(41):5683-5698. doi: 10.3748/wjg.v29.i41.5683. PMID: 38077157Free PMC Article
Ampulla of Vater Carcinoma: Sequencing Analysis Identifies TP53 Status as a Novel Independent Prognostic Factor and Potentially Actionable ERBB, PI3K, and WNT Pathways Gene Mutations.
Mafficini A, Amato E, Cataldo I, Rusev BC, Bertoncello L, Corbo V, Simbolo M, Luchini C, Fassan M, Cantù C, Salvia R, Marchegiani G, Tortora G, Lawlor RT, Bassi C, Scarpa A
Ann Surg 2018 Jan;267(1):149-156. doi: 10.1097/SLA.0000000000001999. PMID: 27611608
KRAS and GNAS mutations and p53 overexpression in biliary intraepithelial neoplasia and intrahepatic cholangiocarcinomas.
Hsu M, Sasaki M, Igarashi S, Sato Y, Nakanuma Y
Cancer 2013 May 1;119(9):1669-74. Epub 2013 Jan 18 doi: 10.1002/cncr.27955. PMID: 23335286
Neoplastic diseases induced by chronic alpha-irradiation--epidemiological, biophysical and clinical results of the German Thorotrast Study.
van Kaick G, Wesch H, Lührs H, Liebermann D, Kaul A
J Radiat Res 1991 Dec;32 Suppl 2:20-33. doi: 10.1269/jrr.32.supplement2_20. PMID: 1823356
Ultrastructure of botryoid sarcoma of the common bile duct.
Taura S, Taura M, Tanaka N, Ito T, Tsuchiya R
Gastroenterol Jpn 1977;12(4):305-10. doi: 10.1007/BF02776799. PMID: 590703

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