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Serrated Lesions and Polyps

MedGen UID:
473643
•Concept ID:
C2732618
•
Neoplastic Process
Synonyms: Serrated Adenoma Type I; Serrated Polyp with Abnormal Proliferation; Sessile serrated adenoma; Sessile Serrated Adenoma; Sessile Serrated Adenoma/Polyp; Sessile Serrated Polyp; Sessile serrated polyp; Sessile Serrated Polyp/Adenoma
SNOMED CT: Sessile serrated adenoma (443157008); Sessile serrated polyp (443157008)

Definition

Polyps that arises from the large intestine and the appendix. They are characterized by the presence of serrated glands and the absence of generalized dysplasia. [from NCI]

Professional guidelines

PubMed

Differential diagnosis of appendiceal serrated lesions and polyps and low-grade appendiceal mucinous neoplasm: analysis of 88 cases.
Lu Y, Qi C, Xu H, Jin M
J Cancer Res Clin Oncol 2022 Jul;148(7):1761-1769. Epub 2021 Aug 9 doi: 10.1007/s00432-021-03757-6. PMID: 34368907

Recent clinical studies

Etiology

Influence of location-dependent sex difference on PD-L1, MMR/MSI, and EGFR in colorectal carcinogenesis.
Choi J, Kim N, Nam RH, Kim JW, Song CH, Na HY, Kang GH
PLoS One 2023;18(2):e0282017. Epub 2023 Feb 21 doi: 10.1371/journal.pone.0282017. PMID: 36802389Free PMC Article

Diagnosis

Influence of location-dependent sex difference on PD-L1, MMR/MSI, and EGFR in colorectal carcinogenesis.
Choi J, Kim N, Nam RH, Kim JW, Song CH, Na HY, Kang GH
PLoS One 2023;18(2):e0282017. Epub 2023 Feb 21 doi: 10.1371/journal.pone.0282017. PMID: 36802389Free PMC Article
Differential diagnosis of appendiceal serrated lesions and polyps and low-grade appendiceal mucinous neoplasm: analysis of 88 cases.
Lu Y, Qi C, Xu H, Jin M
J Cancer Res Clin Oncol 2022 Jul;148(7):1761-1769. Epub 2021 Aug 9 doi: 10.1007/s00432-021-03757-6. PMID: 34368907
Sessile Serrated Lesion of the Appendix in a Teenage Girl.
Dargent JL, Hérin M, Rop C, Druez P, Jouret-Mourin A
Pediatr Dev Pathol 2021 Sep-Oct;24(5):489-492. Epub 2021 May 28 doi: 10.1177/10935266211016186. PMID: 34047219

Clinical prediction guides

Influence of location-dependent sex difference on PD-L1, MMR/MSI, and EGFR in colorectal carcinogenesis.
Choi J, Kim N, Nam RH, Kim JW, Song CH, Na HY, Kang GH
PLoS One 2023;18(2):e0282017. Epub 2023 Feb 21 doi: 10.1371/journal.pone.0282017. PMID: 36802389Free PMC Article
Differential diagnosis of appendiceal serrated lesions and polyps and low-grade appendiceal mucinous neoplasm: analysis of 88 cases.
Lu Y, Qi C, Xu H, Jin M
J Cancer Res Clin Oncol 2022 Jul;148(7):1761-1769. Epub 2021 Aug 9 doi: 10.1007/s00432-021-03757-6. PMID: 34368907
Serrated adenomas with a BRAF mutation in a young patient with familial adenomatous polyposis.
Moriichi K, Tanabe H, Ono Y, Kobayashi Y, Murakami Y, Iwama T, Kunogi T, Sasaki T, Takahashi K, Ando K, Ueno N, Kashima S, Takei H, Mizukami Y, Fujiya M, Okumura T
Int J Colorectal Dis 2020 Oct;35(10):1967-1972. Epub 2020 Jun 5 doi: 10.1007/s00384-020-03657-0. PMID: 32504335

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