U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Colorectal Peutz-Jeghers Polyp

MedGen UID:
473967
Concept ID:
C3272334
Disease or Syndrome
Synonym: Large Intestinal Peutz-Jeghers Polyp

Definition

A non-neoplastic hamartomatous polyp that arises from the colon and rectum. It is characterized by the presence of smooth muscle branching bands, and cystic mucosal changes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColorectal Peutz-Jeghers Polyp

Professional guidelines

PubMed

Boland CR, Idos GE, Durno C, Giardiello FM, Anderson JC, Burke CA, Dominitz JA, Gross S, Gupta S, Jacobson BC, Patel SG, Shaukat A, Syngal S, Robertson DJ
Gastroenterology 2022 Jun;162(7):2063-2085. Epub 2022 Apr 26 doi: 10.1053/j.gastro.2022.02.021. PMID: 35487791
Boland CR, Idos GE, Durno C, Giardiello FM, Anderson JC, Burke CA, Dominitz JA, Gross S, Gupta S, Jacobson BC, Patel SG, Shaukat A, Syngal S, Robertson DJ
Gastrointest Endosc 2022 Jun;95(6):1025-1047. Epub 2022 Apr 26 doi: 10.1016/j.gie.2022.02.044. PMID: 35487765
Järvinen HJ
Gut 2003 May;52 Suppl 2(Suppl 2):ii19-22. doi: 10.1136/gut.52.suppl_2.ii19. PMID: 12651878Free PMC Article

Recent clinical studies

Etiology

Jelsig AM, van Overeem Hansen T, Gede LB, Qvist N, Christensen LL, Lautrup CK, Frederiksen JH, Sunde L, Ousager LB, Ljungmann K, Bertelsen B, Karstensen JG
Clin Genet 2023 Jul;104(1):81-89. Epub 2023 Apr 5 doi: 10.1111/cge.14337. PMID: 37017260
Dal Buono A, Gaiani F, Poliani L, Laghi L
Best Pract Res Clin Gastroenterol 2022 Jun-Aug;58-59:101799. Epub 2022 Apr 4 doi: 10.1016/j.bpg.2022.101799. PMID: 35988962
Ma H, Brosens LAA, Offerhaus GJA, Giardiello FM, de Leng WWJ, Montgomery EA
Pathology 2018 Jan;50(1):49-59. Epub 2017 Nov 21 doi: 10.1016/j.pathol.2017.09.004. PMID: 29169633
Jasperson K, Burt RW
Surg Oncol Clin N Am 2015 Oct;24(4):683-703. Epub 2015 Jul 15 doi: 10.1016/j.soc.2015.06.006. PMID: 26363537
Half E, Bercovich D, Rozen P
Orphanet J Rare Dis 2009 Oct 12;4:22. doi: 10.1186/1750-1172-4-22. PMID: 19822006Free PMC Article

Diagnosis

Jelsig AM, van Overeem Hansen T, Gede LB, Qvist N, Christensen LL, Lautrup CK, Frederiksen JH, Sunde L, Ousager LB, Ljungmann K, Bertelsen B, Karstensen JG
Clin Genet 2023 Jul;104(1):81-89. Epub 2023 Apr 5 doi: 10.1111/cge.14337. PMID: 37017260
Dal Buono A, Gaiani F, Poliani L, Laghi L
Best Pract Res Clin Gastroenterol 2022 Jun-Aug;58-59:101799. Epub 2022 Apr 4 doi: 10.1016/j.bpg.2022.101799. PMID: 35988962
Stoffel EM
Gastroenterol Clin North Am 2016 Sep;45(3):509-27. doi: 10.1016/j.gtc.2016.04.008. PMID: 27546846
Jasperson K, Burt RW
Surg Oncol Clin N Am 2015 Oct;24(4):683-703. Epub 2015 Jul 15 doi: 10.1016/j.soc.2015.06.006. PMID: 26363537
Half E, Bercovich D, Rozen P
Orphanet J Rare Dis 2009 Oct 12;4:22. doi: 10.1186/1750-1172-4-22. PMID: 19822006Free PMC Article

Therapy

Losurdo G, Di Leo M, Rizzi S, Lacavalla I, Celiberto F, Iannone A, Rendina M, Ierardi E, Iabichino G, De Luca L, Di Leo A
Expert Rev Gastroenterol Hepatol 2023 Jul-Dec;17(8):811-816. Epub 2023 Jul 29 doi: 10.1080/17474124.2023.2242240. PMID: 37515779
Zhang Z, Duan FX, Gu GL, Yu PF
World J Gastroenterol 2020 Apr 28;26(16):1926-1937. doi: 10.3748/wjg.v26.i16.1926. PMID: 32390703Free PMC Article
Thakkar K, Fishman DS, Gilger MA
Curr Opin Pediatr 2012 Oct;24(5):632-7. doi: 10.1097/MOP.0b013e328357419f. PMID: 22890064
Ohmiya N, Nakamura M, Takenaka H, Morishima K, Yamamura T, Ishihara M, Miyahara R, Kawashima H, Itoh A, Hirooka Y, Watanabe O, Ando T, Goto H
Gastrointest Endosc 2010 Dec;72(6):1209-16. doi: 10.1016/j.gie.2010.08.018. PMID: 20970791
Burt RW, Bishop DT, Lynch HT, Rozen P, Winawer SJ
Bull World Health Organ 1990;68(5):655-65. PMID: 2289301Free PMC Article

Prognosis

Stanich PP, Pearlman R, Hinton A, Gutierrez S, LaDuca H, Hampel H, Jasperson K
Clin Gastroenterol Hepatol 2019 Sep;17(10):2008-2015.e3. Epub 2018 Dec 14 doi: 10.1016/j.cgh.2018.12.008. PMID: 30557735
Jelsig AM, Qvist N, Sunde L, Brusgaard K, Hansen T, Wikman FP, Nielsen CB, Nielsen IK, Gerdes AM, Bojesen A, Ousager LB
Int J Colorectal Dis 2016 May;31(5):997-1004. Epub 2016 Mar 15 doi: 10.1007/s00384-016-2560-3. PMID: 26979979
Chen HM, Fang JY
Int J Colorectal Dis 2009 Aug;24(8):865-74. Epub 2009 Apr 21 doi: 10.1007/s00384-009-0714-2. PMID: 19381654
Attard TM, Young RJ
Gastroenterol Nurs 2006 Jan-Feb;29(1):16-22; quiz 23-4. doi: 10.1097/00001610-200601000-00003. PMID: 16552295
Oncel M, Remzi FH, Church JM, Goldblum JR, Zutshi M, Fazio VW
Int J Colorectal Dis 2003 Jan;18(1):33-5. Epub 2002 Jun 14 doi: 10.1007/s00384-002-0411-x. PMID: 12458378

Clinical prediction guides

Jelsig AM, van Overeem Hansen T, Gede LB, Qvist N, Christensen LL, Lautrup CK, Frederiksen JH, Sunde L, Ousager LB, Ljungmann K, Bertelsen B, Karstensen JG
Clin Genet 2023 Jul;104(1):81-89. Epub 2023 Apr 5 doi: 10.1111/cge.14337. PMID: 37017260
Zhang Z, Duan FX, Gu GL, Yu PF
World J Gastroenterol 2020 Apr 28;26(16):1926-1937. doi: 10.3748/wjg.v26.i16.1926. PMID: 32390703Free PMC Article
Wei C, Dayong W, Liqun J, Xiaoman W, Yu W, Xiaohong Q
J Pediatr Surg 2012 Oct;47(10):1853-8. doi: 10.1016/j.jpedsurg.2012.05.024. PMID: 23084197
Choi HS, Park YJ, Youk EG, Yoon KA, Ku JL, Kim NK, Kim SM, Kim YJ, Moon DJ, Min JS, Park CJ, Bae OS, Yang DH, Jun SH, Chung ES, Jung PM, Whang Y, Park JG
Int J Colorectal Dis 2000 Feb;15(1):35-8. doi: 10.1007/s003840050005. PMID: 10766089
Järvinen HJ
World J Surg 1991 Jan-Feb;15(1):50-6. doi: 10.1007/BF01658961. PMID: 1994605

Recent systematic reviews

van Lier MG, Wagner A, Mathus-Vliegen EM, Kuipers EJ, Steyerberg EW, van Leerdam ME
Am J Gastroenterol 2010 Jun;105(6):1258-64; author reply 1265. Epub 2010 Jan 5 doi: 10.1038/ajg.2009.725. PMID: 20051941

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...