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Benign Gastric Gastrointestinal Stromal Tumor

MedGen UID:
474052
Concept ID:
C3272419
Neoplastic Process

Definition

A gastrointestinal stromal tumor arising from the stomach. It is characterized by a maximum diameter equal or less than 5 cm and no more than 5 mitotic figures per 50 high power fields. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Gastric Gastrointestinal Stromal Tumor

Professional guidelines

PubMed

Jacobson BC, Bhatt A, Greer KB, Lee LS, Park WG, Sauer BG, Shami VM
Am J Gastroenterol 2023 Jan 1;118(1):46-58. Epub 2022 Sep 6 doi: 10.14309/ajg.0000000000002100. PMID: 36602835
Deprez PH, Moons LMG, OʼToole D, Gincul R, Seicean A, Pimentel-Nunes P, Fernández-Esparrach G, Polkowski M, Vieth M, Borbath I, Moreels TG, Nieveen van Dijkum E, Blay JY, van Hooft JE
Endoscopy 2022 Apr;54(4):412-429. Epub 2022 Feb 18 doi: 10.1055/a-1751-5742. PMID: 35180797
Akahoshi K, Oya M, Koga T, Shiratsuchi Y
World J Gastroenterol 2018 Jul 14;24(26):2806-2817. doi: 10.3748/wjg.v24.i26.2806. PMID: 30018476Free PMC Article

Recent clinical studies

Etiology

Jacobson BC, Bhatt A, Greer KB, Lee LS, Park WG, Sauer BG, Shami VM
Am J Gastroenterol 2023 Jan 1;118(1):46-58. Epub 2022 Sep 6 doi: 10.14309/ajg.0000000000002100. PMID: 36602835
Deprez PH, Moons LMG, OʼToole D, Gincul R, Seicean A, Pimentel-Nunes P, Fernández-Esparrach G, Polkowski M, Vieth M, Borbath I, Moreels TG, Nieveen van Dijkum E, Blay JY, van Hooft JE
Endoscopy 2022 Apr;54(4):412-429. Epub 2022 Feb 18 doi: 10.1055/a-1751-5742. PMID: 35180797
Nishida T, Goto O, Raut CP, Yahagi N
Cancer 2016 Oct 15;122(20):3110-3118. Epub 2016 Aug 1 doi: 10.1002/cncr.30239. PMID: 27478963Free PMC Article
Joensuu H, Hohenberger P, Corless CL
Lancet 2013 Sep 14;382(9896):973-83. Epub 2013 Apr 24 doi: 10.1016/S0140-6736(13)60106-3. PMID: 23623056
Miettinen M, Sarlomo-Rikala M, Lasota J
Ann Chir Gynaecol 1998;87(4):278-81. PMID: 9891765

Diagnosis

Jacobson BC, Bhatt A, Greer KB, Lee LS, Park WG, Sauer BG, Shami VM
Am J Gastroenterol 2023 Jan 1;118(1):46-58. Epub 2022 Sep 6 doi: 10.14309/ajg.0000000000002100. PMID: 36602835
Deprez PH, Moons LMG, OʼToole D, Gincul R, Seicean A, Pimentel-Nunes P, Fernández-Esparrach G, Polkowski M, Vieth M, Borbath I, Moreels TG, Nieveen van Dijkum E, Blay JY, van Hooft JE
Endoscopy 2022 Apr;54(4):412-429. Epub 2022 Feb 18 doi: 10.1055/a-1751-5742. PMID: 35180797
Akahoshi K, Oya M, Koga T, Shiratsuchi Y
World J Gastroenterol 2018 Jul 14;24(26):2806-2817. doi: 10.3748/wjg.v24.i26.2806. PMID: 30018476Free PMC Article
Joensuu H, Hohenberger P, Corless CL
Lancet 2013 Sep 14;382(9896):973-83. Epub 2013 Apr 24 doi: 10.1016/S0140-6736(13)60106-3. PMID: 23623056
Shaib YH, Rugge M, Graham DY, Genta RM
Clin Gastroenterol Hepatol 2013 Nov;11(11):1374-84. Epub 2013 Apr 10 doi: 10.1016/j.cgh.2013.03.019. PMID: 23583466Free PMC Article

Therapy

Akahoshi K, Oya M, Koga T, Shiratsuchi Y
World J Gastroenterol 2018 Jul 14;24(26):2806-2817. doi: 10.3748/wjg.v24.i26.2806. PMID: 30018476Free PMC Article
Lin YM, Chiu NC, Li AF, Liu CA, Chou YH, Chiou YY
World J Gastroenterol 2017 Apr 14;23(14):2493-2504. doi: 10.3748/wjg.v23.i14.2493. PMID: 28465633Free PMC Article
Iorio N, Sawaya RA, Friedenberg FK
Aliment Pharmacol Ther 2014 Jun;39(12):1376-86. Epub 2014 Apr 20 doi: 10.1111/apt.12761. PMID: 24749828
Joensuu H, Hohenberger P, Corless CL
Lancet 2013 Sep 14;382(9896):973-83. Epub 2013 Apr 24 doi: 10.1016/S0140-6736(13)60106-3. PMID: 23623056
Miettinen M, El-Rifai W, H L Sobin L, Lasota J
Hum Pathol 2002 May;33(5):478-83. doi: 10.1053/hupa.2002.124123. PMID: 12094372

Prognosis

Akahoshi K, Oya M, Koga T, Shiratsuchi Y
World J Gastroenterol 2018 Jul 14;24(26):2806-2817. doi: 10.3748/wjg.v24.i26.2806. PMID: 30018476Free PMC Article
Lin YM, Chiu NC, Li AF, Liu CA, Chou YH, Chiou YY
World J Gastroenterol 2017 Apr 14;23(14):2493-2504. doi: 10.3748/wjg.v23.i14.2493. PMID: 28465633Free PMC Article
Nishida T, Goto O, Raut CP, Yahagi N
Cancer 2016 Oct 15;122(20):3110-3118. Epub 2016 Aug 1 doi: 10.1002/cncr.30239. PMID: 27478963Free PMC Article
Cichoz-Lach H, Kasztelan-Szczerbińska B, Słomka M
Pol Arch Med Wewn 2008 Apr;118(4):216-21. PMID: 18575421
Miettinen M, El-Rifai W, H L Sobin L, Lasota J
Hum Pathol 2002 May;33(5):478-83. doi: 10.1053/hupa.2002.124123. PMID: 12094372

Clinical prediction guides

Courelli AS, Sharma AK, Madlensky L, Choi YY, Li S, Sarno S, Kelly K, Mehtsun W, Horgan S, Harismendy O, Baumgartner JM, Sicklick JK
Ann Surg Oncol 2022 Nov;29(12):7542-7548. Epub 2022 Jul 18 doi: 10.1245/s10434-022-12211-x. PMID: 35849291Free PMC Article
Buldanlı MZ, Yener O
Prague Med Rep 2022;123(1):20-26. doi: 10.14712/23362936.2022.2. PMID: 35248161
Lin YM, Chiu NC, Li AF, Liu CA, Chou YH, Chiou YY
World J Gastroenterol 2017 Apr 14;23(14):2493-2504. doi: 10.3748/wjg.v23.i14.2493. PMID: 28465633Free PMC Article
Ricci R, Martini M, Cenci T, Carbone A, Lanza P, Biondi A, Rindi G, Cassano A, Larghi A, Persiani R, Larocca LM
Mod Pathol 2015 Jul;28(7):954-64. Epub 2015 May 15 doi: 10.1038/modpathol.2015.56. PMID: 25975287
Cichoz-Lach H, Kasztelan-Szczerbińska B, Słomka M
Pol Arch Med Wewn 2008 Apr;118(4):216-21. PMID: 18575421

Recent systematic reviews

Fukazawa M, Koga H, Hiroshige S, Matsumoto T, Nakazono Y, Yoshikawa Y
Medicine (Baltimore) 2019 Jan;98(3):e14186. doi: 10.1097/MD.0000000000014186. PMID: 30653169Free PMC Article

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