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Small Intestinal B-Cell Non-Hodgkin Lymphoma

MedGen UID:
474153
•Concept ID:
C3272520
•
Neoplastic Process

Definition

A B-cell non-Hodgkin lymphoma that arises from the small intestine. Representative examples include diffuse large B-cell lymphoma, mucosa-associated lymphoid tissue lymphoma, alpha heavy chain disease/immunoproliferative small intestinal disease, Burkitt lymphoma, follicular lymphoma, and mantle cell lymphoma. [from NCI]

Professional guidelines

PubMed

Review of lymphoma in the duodenum: An update of diagnosis and management.
Iwamuro M, Tanaka T, Okada H
World J Gastroenterol 2023 Mar 28;29(12):1852-1862. doi: 10.3748/wjg.v29.i12.1852. PMID: 37032723Free PMC Article
Idelalisib for treatment of B-cell malignancies.
Do B, Mace M, Rexwinkle A
Am J Health Syst Pharm 2016 Apr 15;73(8):547-55. Epub 2016 Mar 1 doi: 10.2146/ajhp150281. PMID: 26933132
Gastrointestinal lymphoma: recent advances in diagnosis and treatment.
Nakamura S, Matsumoto T
Digestion 2013;87(3):182-8. Epub 2013 Apr 27 doi: 10.1159/000350051. PMID: 23635497

Recent clinical studies

Etiology

B Cell Lymphomas of the GI Tract.
Small S, Barnea Slonim L, Williams C, Karmali R
Curr Gastroenterol Rep 2021 May 8;23(7):9. doi: 10.1007/s11894-021-00811-8. PMID: 33963950
New developments in non-Hodgkin lymphoid malignancies.
Ganapathi KA, Brown LE, Prakash S, Bhargava P
Pathology 2021 Apr;53(3):349-366. Epub 2021 Mar 5 doi: 10.1016/j.pathol.2021.01.002. PMID: 33685720
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
Cryoglobulinemia Vasculitis.
Cacoub P, Comarmond C, Domont F, Savey L, Saadoun D
Am J Med 2015 Sep;128(9):950-5. Epub 2015 Mar 30 doi: 10.1016/j.amjmed.2015.02.017. PMID: 25837517
Gastrointestinal lymphoma.
Isaacson PG
Hum Pathol 1994 Oct;25(10):1020-9. doi: 10.1016/0046-8177(94)90060-4. PMID: 7927306

Diagnosis

Review of lymphoma in the duodenum: An update of diagnosis and management.
Iwamuro M, Tanaka T, Okada H
World J Gastroenterol 2023 Mar 28;29(12):1852-1862. doi: 10.3748/wjg.v29.i12.1852. PMID: 37032723Free PMC Article
B Cell Lymphomas of the GI Tract.
Small S, Barnea Slonim L, Williams C, Karmali R
Curr Gastroenterol Rep 2021 May 8;23(7):9. doi: 10.1007/s11894-021-00811-8. PMID: 33963950
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
Cryoglobulinemia Vasculitis.
Cacoub P, Comarmond C, Domont F, Savey L, Saadoun D
Am J Med 2015 Sep;128(9):950-5. Epub 2015 Mar 30 doi: 10.1016/j.amjmed.2015.02.017. PMID: 25837517
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article

Therapy

Extensive small intestinal diffuse large B cell lymphoma.
Liu X, Lv T, Zhang X, Li J
Rev Esp Enferm Dig 2023 May;115(5):267. doi: 10.17235/reed.2022.9100/2022. PMID: 36043558
Idelalisib for treatment of B-cell malignancies.
Do B, Mace M, Rexwinkle A
Am J Health Syst Pharm 2016 Apr 15;73(8):547-55. Epub 2016 Mar 1 doi: 10.2146/ajhp150281. PMID: 26933132
Management of the marginal zone lymphomas.
Vannata B, Stathis A, Zucca E
Cancer Treat Res 2015;165:227-49. doi: 10.1007/978-3-319-13150-4_9. PMID: 25655612
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article
Role of radiotherapy in the treatment of lymphomas of the gastrointestinal tract.
Aleman BM, Haas RL, van der Maazen RW
Best Pract Res Clin Gastroenterol 2010 Feb;24(1):27-34. doi: 10.1016/j.bpg.2009.12.002. PMID: 20206106

Prognosis

Primary small intestinal non-Hodgkin lymphoma diagnosed after emergency surgery.
Avcı T, Yabanoğlu H, Arer İM, Koçer NE, Çalışkan K, Börcek P, Ekici Y
Ulus Travma Acil Cerrahi Derg 2017 Mar;23(2):128-133. doi: 10.5505/tjtes.2016.02359. PMID: 28467579
Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Cryoglobulinemia Vasculitis.
Cacoub P, Comarmond C, Domont F, Savey L, Saadoun D
Am J Med 2015 Sep;128(9):950-5. Epub 2015 Mar 30 doi: 10.1016/j.amjmed.2015.02.017. PMID: 25837517
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article
Gastrointestinal lymphoma.
Isaacson PG
Hum Pathol 1994 Oct;25(10):1020-9. doi: 10.1016/0046-8177(94)90060-4. PMID: 7927306

Clinical prediction guides

Pathogenesis of Gastrointestinal Follicular Lymphomas: Consideration Based on Histopathology and Endoscopic Findings.
Takahashi Y, Taniguchi H, Haruhi F, Hattori D, Sasaki H, Makita S, Iwaki N, Fukuhara S, Munakata W, Saito Y, Izutsu K, Maeshima AM
Am J Surg Pathol 2023 Oct 1;47(10):1134-1143. Epub 2023 Jul 27 doi: 10.1097/PAS.0000000000002095. PMID: 37493666
The role of "watch and wait" in intestinal follicular lymphoma in rituximab era.
Tari A, Asaoku H, Takata K, Fujimori S, Tanaka S, Fujihara M, Koga T, Yoshino T
Scand J Gastroenterol 2016 Mar;51(3):321-8. Epub 2015 Sep 18 doi: 10.3109/00365521.2015.1087589. PMID: 26382560
Multiple Intestinal Lymphoma.
Mastalier B, Deaconescu V, Elaiah W, Drăghici C, Popp C, Zurac S, Balea M, Tevet M, Botezatu C
Rom J Intern Med 2015 Jan-Mar;53(1):73-8. doi: 10.1515/rjim-2015-0010. PMID: 26076564
Primary intestinal lymphangiectasia (Waldmann's disease).
Vignes S, Bellanger J
Orphanet J Rare Dis 2008 Feb 22;3:5. doi: 10.1186/1750-1172-3-5. PMID: 18294365Free PMC Article
Pathology of intestinal lymphomas.
Foss HD, Stein H
Recent Results Cancer Res 2000;156:33-41. doi: 10.1007/978-3-642-57054-4_5. PMID: 10802861

Recent systematic reviews

Emergency laparotomy for abdominal catastrophes secondary to lymphoma: A systematic review.
Butterworth JW, Brooker-Thompson C, Qureshi YA, Mohammadi B, Dawas K
Eur J Surg Oncol 2024 Jan;50(1):107268. Epub 2023 Nov 19 doi: 10.1016/j.ejso.2023.107268. PMID: 38043361
Treating chronic diarrhea: A systematic review on Immunoproliferative Small Intestinal Disease (IPSID).
Evangelista-Leite D, Affonso Madaloso B, Shouta Yamashita B, Enrico Aloise F, Polito Verdasca L, Lopes de Mello M, Murata Hayashi R, Zimberg Chehter E
PLoS One 2021;16(7):e0253695. Epub 2021 Jul 16 doi: 10.1371/journal.pone.0253695. PMID: 34270561Free PMC Article
Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Composite EBV negative peripheral T-cell lymphoma and diffuse large B-cell lymphoma involving the ileum: a case report and a systematic review of the literature.
Abou-Elella AA, Nifong TP
Leuk Lymphoma 2006 Oct;47(10):2208-17. doi: 10.1080/10428190600763348. PMID: 17071497

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