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Colorectal Adenomatous Polyp

MedGen UID:
474438
Concept ID:
C3272805
Neoplastic Process
Synonyms: Adenomatous Polyp of Large Bowel; Adenomatous Polyp of the Large Bowel; Large Bowel Adenomatous Polyp

Definition

A polypoid adenoma that arises from and protrudes into the lumen of the colon or rectum. Epithelial dysplasia is always present. According to the architectural pattern it is classified as tubular, tubulovillous, or villous. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColorectal Adenomatous Polyp

Professional guidelines

PubMed

Weiss JM, Gupta S, Burke CA, Axell L, Chen LM, Chung DC, Clayback KM, Dallas S, Felder S, Gbolahan O, Giardiello FM, Grady W, Hall MJ, Hampel H, Hodan R, Idos G, Kanth P, Katona B, Lamps L, Llor X, Lynch PM, Markowitz AJ, Pirzadeh-Miller S, Samadder NJ, Shibata D, Swanson BJ, Szymaniak BM, Wiesner GL, Wolf A, Yurgelun MB, Zakhour M, Darlow SD, Dwyer MA, Campbell M
J Natl Compr Canc Netw 2021 Oct 15;19(10):1122-1132. doi: 10.1164/jnccn.2021.0048. PMID: 34666312
US Preventive Services Task Force, Davidson KW, Barry MJ, Mangione CM, Cabana M, Caughey AB, Davis EM, Donahue KE, Doubeni CA, Krist AH, Kubik M, Li L, Ogedegbe G, Owens DK, Pbert L, Silverstein M, Stevermer J, Tseng CW, Wong JB
JAMA 2021 May 18;325(19):1965-1977. doi: 10.1001/jama.2021.6238. PMID: 34003218
Syngal S, Brand RE, Church JM, Giardiello FM, Hampel HL, Burt RW; American College of Gastroenterology
Am J Gastroenterol 2015 Feb;110(2):223-62; quiz 263. Epub 2015 Feb 3 doi: 10.1038/ajg.2014.435. PMID: 25645574Free PMC Article

Recent clinical studies

Etiology

Davies JR, Mell T, Fuller H, Harland M, Saleh RNM, Race AD, Rees CJ, Brown LC, Loadman PM, Downing A, Minihane AM, Williams EA, Hull MA
Cancer Prev Res (Phila) 2023 Nov 1;16(11):621-629. doi: 10.1158/1940-6207.CAPR-23-0111. PMID: 37756582Free PMC Article
Feng Z, Lin H, Yang X, Cao S, Gu X, Zhang Z, Deng W
Cancer Control 2023 Jan-Dec;30:10732748231180745. doi: 10.1177/10732748231180745. PMID: 37421141Free PMC Article
Kim H, Cho YJ, Kim YA, Gwak SG
Int J Environ Res Public Health 2018 Dec 6;15(12) doi: 10.3390/ijerph15122762. PMID: 30563254Free PMC Article
Erim T, Rivas JM, Velis E, Castro F
World J Gastroenterol 2011 Sep 21;17(35):4001-6. doi: 10.3748/wjg.v17.i35.4001. PMID: 22046088Free PMC Article
Kim HB, Lee HR, Shim JY, Na HY, Park BJ, Jung DH, Lee YJ
J Womens Health (Larchmt) 2011 May;20(5):765-9. Epub 2011 Mar 31 doi: 10.1089/jwh.2010.2538. PMID: 21453035

Diagnosis

Feng Z, Lin H, Yang X, Cao S, Gu X, Zhang Z, Deng W
Cancer Control 2023 Jan-Dec;30:10732748231180745. doi: 10.1177/10732748231180745. PMID: 37421141Free PMC Article
Chun EM, Kim SW, Lim SY
Int J Chron Obstruct Pulmon Dis 2015;10:955-60. Epub 2015 May 18 doi: 10.2147/COPD.S83341. PMID: 26028968Free PMC Article
Siamakpour-Reihani S, Scarbrough PM, Wang F, Spasojevic I, Base K, Sedjo R, D'Agostino RB Jr, Il'yasova D
Ann Epidemiol 2012 Aug;22(8):587-91. Epub 2012 Jun 12 doi: 10.1016/j.annepidem.2012.05.001. PMID: 22695388Free PMC Article
Erim T, Rivas JM, Velis E, Castro F
World J Gastroenterol 2011 Sep 21;17(35):4001-6. doi: 10.3748/wjg.v17.i35.4001. PMID: 22046088Free PMC Article
Hayes SJ
Gastrointest Endosc 2009 Sep;70(3):540-1. Epub 2009 Jun 24 doi: 10.1016/j.gie.2009.04.017. PMID: 19555943

Therapy

Davies JR, Mell T, Fuller H, Harland M, Saleh RNM, Race AD, Rees CJ, Brown LC, Loadman PM, Downing A, Minihane AM, Williams EA, Hull MA
Cancer Prev Res (Phila) 2023 Nov 1;16(11):621-629. doi: 10.1158/1940-6207.CAPR-23-0111. PMID: 37756582Free PMC Article
Zhou Q, Chen YG, Xiao J, Chen TT, Liu JR, Zhou W, Li WZ, Wang Y, Zhang BP, Lin J, Meng FD, Gong B, Zheng GY, Han ST, Cheng HB
Medicine (Baltimore) 2019 Aug;98(31):e16680. doi: 10.1097/MD.0000000000016680. PMID: 31374049Free PMC Article
Chun EM, Kim SW, Lim SY
Int J Chron Obstruct Pulmon Dis 2015;10:955-60. Epub 2015 May 18 doi: 10.2147/COPD.S83341. PMID: 26028968Free PMC Article
Erim T, Rivas JM, Velis E, Castro F
World J Gastroenterol 2011 Sep 21;17(35):4001-6. doi: 10.3748/wjg.v17.i35.4001. PMID: 22046088Free PMC Article
Alberts DS, Einspahr JG, Earnest DL, Krutzsch MF, Lin P, Hess LM, Heddens DK, Roe DJ, Martínez ME, Salen G, Batta AK
Cancer Epidemiol Biomarkers Prev 2003 Mar;12(3):197-200. PMID: 12646507

Prognosis

Davies JR, Mell T, Fuller H, Harland M, Saleh RNM, Race AD, Rees CJ, Brown LC, Loadman PM, Downing A, Minihane AM, Williams EA, Hull MA
Cancer Prev Res (Phila) 2023 Nov 1;16(11):621-629. doi: 10.1158/1940-6207.CAPR-23-0111. PMID: 37756582Free PMC Article
Kim H, Cho YJ, Kim YA, Gwak SG
Int J Environ Res Public Health 2018 Dec 6;15(12) doi: 10.3390/ijerph15122762. PMID: 30563254Free PMC Article
Kasap E, Gerceker E, Boyacıoglu SÖ, Yuceyar H, Yıldırm H, Ayhan S, Korkmaz M
Tumour Biol 2016 Mar;37(3):3071-80. Epub 2015 Sep 30 doi: 10.1007/s13277-015-4131-6. PMID: 26423403
Chun EM, Kim SW, Lim SY
Int J Chron Obstruct Pulmon Dis 2015;10:955-60. Epub 2015 May 18 doi: 10.2147/COPD.S83341. PMID: 26028968Free PMC Article
Wang D, Xu MR, Wang T, Li T, Zhu Jw
J Gastrointest Surg 2011 Jul;15(7):1205-12. Epub 2011 May 12 doi: 10.1007/s11605-011-1546-2. PMID: 21562916

Clinical prediction guides

Davies JR, Mell T, Fuller H, Harland M, Saleh RNM, Race AD, Rees CJ, Brown LC, Loadman PM, Downing A, Minihane AM, Williams EA, Hull MA
Cancer Prev Res (Phila) 2023 Nov 1;16(11):621-629. doi: 10.1158/1940-6207.CAPR-23-0111. PMID: 37756582Free PMC Article
Kim H, Cho YJ, Kim YA, Gwak SG
Int J Environ Res Public Health 2018 Dec 6;15(12) doi: 10.3390/ijerph15122762. PMID: 30563254Free PMC Article
Kasap E, Gerceker E, Boyacıoglu SÖ, Yuceyar H, Yıldırm H, Ayhan S, Korkmaz M
Tumour Biol 2016 Mar;37(3):3071-80. Epub 2015 Sep 30 doi: 10.1007/s13277-015-4131-6. PMID: 26423403
Chun EM, Kim SW, Lim SY
Int J Chron Obstruct Pulmon Dis 2015;10:955-60. Epub 2015 May 18 doi: 10.2147/COPD.S83341. PMID: 26028968Free PMC Article
Lee YJ, Myung SK, Cho B, Park BJ, Park JH, Ju W, Park MS, Choi JH
Cancer Causes Control 2011 Jul;22(7):1021-35. Epub 2011 May 22 doi: 10.1007/s10552-011-9777-9. PMID: 21604177

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