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Colorectal Benign Granular Cell Tumor

MedGen UID:
474471
•Concept ID:
C3272838
•
Neoplastic Process

Definition

A granular cell tumor that arises from the colon or rectum and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColorectal Benign Granular Cell Tumor

Professional guidelines

PubMed

Gastrointestinal (GI) leiomyosarcoma (LMS) case series and review on diagnosis, management, and prognosis.
Hilal L, Barada K, Mukherji D, Temraz S, Shamseddine A
Med Oncol 2016 Feb;33(2):20. Epub 2016 Jan 20 doi: 10.1007/s12032-016-0730-3. PMID: 26786155
The role of body composition evaluation by computerized tomography in determining colorectal cancer treatment outcomes: a systematic review.
Malietzis G, Aziz O, Bagnall NM, Johns N, Fearon KC, Jenkins JT
Eur J Surg Oncol 2015 Feb;41(2):186-96. Epub 2014 Nov 3 doi: 10.1016/j.ejso.2014.10.056. PMID: 25468746
Genetic testing by cancer site: uterus.
Daniels MS
Cancer J 2012 Jul-Aug;18(4):338-42. doi: 10.1097/PPO.0b013e3182610cc2. PMID: 22846735

Recent clinical studies

Etiology

Gynecological lesions in hereditary cancer predisposition syndromes.
Dundr P, Cibula D, Foretová L, Macek M Jr, Kopečková K, Petruželka L, Němejcová K, Bártů M, Hojný J, Hájková N, Jakša R, Janega P, Stružinská I
Cesk Patol 2021 Summer;57(2):96-104. PMID: 34275319
Role of ion channels in gastrointestinal cancer.
Anderson KJ, Cormier RT, Scott PM
World J Gastroenterol 2019 Oct 14;25(38):5732-5772. doi: 10.3748/wjg.v25.i38.5732. PMID: 31636470Free PMC Article
Multitarget stool DNA testing for colorectal-cancer screening.
Imperiale TF, Ransohoff DF, Itzkowitz SH, Levin TR, Lavin P, Lidgard GP, Ahlquist DA, Berger BM
N Engl J Med 2014 Apr 3;370(14):1287-97. Epub 2014 Mar 19 doi: 10.1056/NEJMoa1311194. PMID: 24645800
Screening for uterine tumours.
Van den Bosch T, Coosemans A, Morina M, Timmerman D, Amant F
Best Pract Res Clin Obstet Gynaecol 2012 Apr;26(2):257-66. Epub 2011 Nov 9 doi: 10.1016/j.bpobgyn.2011.08.002. PMID: 22078749
Hepatic artery chemoembolization.
Sullivan KL
Semin Oncol 2002 Apr;29(2):145-51. doi: 10.1053/sonc.2002.31671. PMID: 11951212

Diagnosis

Leiomyosarcoma of the Mesentery.
Arhin MA, DeMatos P
Am Surg 2022 Sep;88(9):2210-2211. Epub 2022 Apr 14 doi: 10.1177/00031348221087921. PMID: 35420902
The Role of Tumor Microenvironment Cells in Colorectal Cancer (CRC) Cachexia.
Kasprzak A
Int J Mol Sci 2021 Feb 4;22(4) doi: 10.3390/ijms22041565. PMID: 33557173Free PMC Article
Giant multilocular prostatic cystadenoma.
Nakamura Y, Shida D, Shibayama T, Yoshida A, Matsui Y, Shinoda Y, Iwata S, Kanemitsu Y
World J Surg Oncol 2019 Feb 26;17(1):42. doi: 10.1186/s12957-019-1579-7. PMID: 30808350Free PMC Article
The Role of PDGFs and PDGFRs in Colorectal Cancer.
Manzat Saplacan RM, Balacescu L, Gherman C, Chira RI, Craiu A, Mircea PA, Lisencu C, Balacescu O
Mediators Inflamm 2017;2017:4708076. Epub 2017 Jan 10 doi: 10.1155/2017/4708076. PMID: 28163397Free PMC Article
Multitarget stool DNA testing for colorectal-cancer screening.
Imperiale TF, Ransohoff DF, Itzkowitz SH, Levin TR, Lavin P, Lidgard GP, Ahlquist DA, Berger BM
N Engl J Med 2014 Apr 3;370(14):1287-97. Epub 2014 Mar 19 doi: 10.1056/NEJMoa1311194. PMID: 24645800

Therapy

Role of ion channels in gastrointestinal cancer.
Anderson KJ, Cormier RT, Scott PM
World J Gastroenterol 2019 Oct 14;25(38):5732-5772. doi: 10.3748/wjg.v25.i38.5732. PMID: 31636470Free PMC Article
A systematic review: perivascular epithelioid cell tumor of gastrointestinal tract.
Chen Z, Han S, Wu J, Xiong M, Huang Y, Chen J, Yuan Y, Peng J, Song W
Medicine (Baltimore) 2016 Jul;95(28):e3890. doi: 10.1097/MD.0000000000003890. PMID: 27428182Free PMC Article
Multitarget stool DNA testing for colorectal-cancer screening.
Imperiale TF, Ransohoff DF, Itzkowitz SH, Levin TR, Lavin P, Lidgard GP, Ahlquist DA, Berger BM
N Engl J Med 2014 Apr 3;370(14):1287-97. Epub 2014 Mar 19 doi: 10.1056/NEJMoa1311194. PMID: 24645800
Screening for uterine tumours.
Van den Bosch T, Coosemans A, Morina M, Timmerman D, Amant F
Best Pract Res Clin Obstet Gynaecol 2012 Apr;26(2):257-66. Epub 2011 Nov 9 doi: 10.1016/j.bpobgyn.2011.08.002. PMID: 22078749
Hepatic artery chemoembolization.
Sullivan KL
Semin Oncol 2002 Apr;29(2):145-51. doi: 10.1053/sonc.2002.31671. PMID: 11951212

Prognosis

The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis.
Kobayashi H, Gieniec KA, Lannagan TRM, Wang T, Asai N, Mizutani Y, Iida T, Ando R, Thomas EM, Sakai A, Suzuki N, Ichinose M, Wright JA, Vrbanac L, Ng JQ, Goyne J, Radford G, Lawrence MJ, Sammour T, Hayakawa Y, Klebe S, Shin AE, Asfaha S, Bettington ML, Rieder F, Arpaia N, Danino T, Butler LM, Burt AD, Leedham SJ, Rustgi AK, Mukherjee S, Takahashi M, Wang TC, Enomoto A, Woods SL, Worthley DL
Gastroenterology 2022 Mar;162(3):890-906. Epub 2021 Dec 6 doi: 10.1053/j.gastro.2021.11.037. PMID: 34883119Free PMC Article
The Role of Tumor Microenvironment Cells in Colorectal Cancer (CRC) Cachexia.
Kasprzak A
Int J Mol Sci 2021 Feb 4;22(4) doi: 10.3390/ijms22041565. PMID: 33557173Free PMC Article
The Role of CTHRC1 in Regulation of Multiple Signaling and Tumor Progression and Metastasis.
Mei D, Zhu Y, Zhang L, Wei W
Mediators Inflamm 2020;2020:9578701. Epub 2020 Aug 12 doi: 10.1155/2020/9578701. PMID: 32848510Free PMC Article
Role of ion channels in gastrointestinal cancer.
Anderson KJ, Cormier RT, Scott PM
World J Gastroenterol 2019 Oct 14;25(38):5732-5772. doi: 10.3748/wjg.v25.i38.5732. PMID: 31636470Free PMC Article
The Role of PDGFs and PDGFRs in Colorectal Cancer.
Manzat Saplacan RM, Balacescu L, Gherman C, Chira RI, Craiu A, Mircea PA, Lisencu C, Balacescu O
Mediators Inflamm 2017;2017:4708076. Epub 2017 Jan 10 doi: 10.1155/2017/4708076. PMID: 28163397Free PMC Article

Clinical prediction guides

The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis.
Kobayashi H, Gieniec KA, Lannagan TRM, Wang T, Asai N, Mizutani Y, Iida T, Ando R, Thomas EM, Sakai A, Suzuki N, Ichinose M, Wright JA, Vrbanac L, Ng JQ, Goyne J, Radford G, Lawrence MJ, Sammour T, Hayakawa Y, Klebe S, Shin AE, Asfaha S, Bettington ML, Rieder F, Arpaia N, Danino T, Butler LM, Burt AD, Leedham SJ, Rustgi AK, Mukherjee S, Takahashi M, Wang TC, Enomoto A, Woods SL, Worthley DL
Gastroenterology 2022 Mar;162(3):890-906. Epub 2021 Dec 6 doi: 10.1053/j.gastro.2021.11.037. PMID: 34883119Free PMC Article
Inflammation-induced cholestasis in cancer cachexia.
Thibaut MM, Sboarina M, Roumain M, Pötgens SA, Neyrinck AM, Destrée F, Gillard J, Leclercq IA, Dachy G, Demoulin JB, Tailleux A, Lestavel S, Rastelli M, Everard A, Cani PD, Porporato PE, Loumaye A, Thissen JP, Muccioli GG, Delzenne NM, Bindels LB
J Cachexia Sarcopenia Muscle 2021 Feb;12(1):70-90. Epub 2020 Dec 22 doi: 10.1002/jcsm.12652. PMID: 33350058Free PMC Article
The Role of CTHRC1 in Regulation of Multiple Signaling and Tumor Progression and Metastasis.
Mei D, Zhu Y, Zhang L, Wei W
Mediators Inflamm 2020;2020:9578701. Epub 2020 Aug 12 doi: 10.1155/2020/9578701. PMID: 32848510Free PMC Article
The Role of PDGFs and PDGFRs in Colorectal Cancer.
Manzat Saplacan RM, Balacescu L, Gherman C, Chira RI, Craiu A, Mircea PA, Lisencu C, Balacescu O
Mediators Inflamm 2017;2017:4708076. Epub 2017 Jan 10 doi: 10.1155/2017/4708076. PMID: 28163397Free PMC Article
Clinical significance of incidental focal colorectal (18)F-fluorodeoxyglucose uptake: our experience and a review of the literature.
Treglia G, Calcagni ML, Rufini V, Leccisotti L, Meduri GM, Spitilli MG, Dambra DP, De Gaetano AM, Giordano A
Colorectal Dis 2012 Feb;14(2):174-80. doi: 10.1111/j.1463-1318.2011.02588.x. PMID: 21689289

Recent systematic reviews

Body Composition and Dose-limiting Toxicity in Colorectal Cancer Chemotherapy Treatment; a Systematic Review of the Literature. Could Muscle Mass be the New Body Surface Area in Chemotherapy Dosing?
Drami I, Pring ET, Gould L, Malietzis G, Naghibi M, Athanasiou T, Glynne-Jones R, Jenkins JT
Clin Oncol (R Coll Radiol) 2021 Dec;33(12):e540-e552. Epub 2021 Jun 17 doi: 10.1016/j.clon.2021.05.011. PMID: 34147322
Liver resection for sarcoma metastases: A systematic review and experience from two European centres.
Tirotta F, Hodson J, Parente A, Pasquali S, Sutcliffe R, Desai A, Muiesan P, Ford SJ, Fiore M, Gronchi A, Almond LM
Eur J Surg Oncol 2020 Oct;46(10 Pt A):1807-1813. Epub 2020 Jun 4 doi: 10.1016/j.ejso.2020.05.024. PMID: 32798014
Myosteatosis and prognosis in cancer: Systematic review and meta-analysis.
Aleixo GFP, Shachar SS, Nyrop KA, Muss HB, Malpica L, Williams GR
Crit Rev Oncol Hematol 2020 Jan;145:102839. Epub 2019 Dec 20 doi: 10.1016/j.critrevonc.2019.102839. PMID: 31877534
A systematic review: perivascular epithelioid cell tumor of gastrointestinal tract.
Chen Z, Han S, Wu J, Xiong M, Huang Y, Chen J, Yuan Y, Peng J, Song W
Medicine (Baltimore) 2016 Jul;95(28):e3890. doi: 10.1097/MD.0000000000003890. PMID: 27428182Free PMC Article
The role of body composition evaluation by computerized tomography in determining colorectal cancer treatment outcomes: a systematic review.
Malietzis G, Aziz O, Bagnall NM, Johns N, Fearon KC, Jenkins JT
Eur J Surg Oncol 2015 Feb;41(2):186-96. Epub 2014 Nov 3 doi: 10.1016/j.ejso.2014.10.056. PMID: 25468746

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