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Low Grade Liver Dysplastic Nodule

MedGen UID:
474651
Concept ID:
C3273018
Neoplastic Process
Synonym: Low Grade Hepatic Dysplastic Nodule

Definition

A hepatic dysplastic nodule characterized by the presence of low grade atypical cellular changes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLow Grade Liver Dysplastic Nodule

Professional guidelines

PubMed

Bakheet AMH, Zhao C, Chen JN, Zhang JY, Huang JT, Du Y, Gong LP, Bi YH, Shao CK
Hepatol Int 2020 Jan;14(1):96-104. Epub 2019 Dec 12 doi: 10.1007/s12072-019-10006-z. PMID: 31832976
Kudo M
Clin Gastroenterol Hepatol 2005 Oct;3(10 Suppl 2):S144-8. doi: 10.1016/s1542-3565(05)00712-3. PMID: 16234064
Hytiroglou P, Theise ND
Semin Diagn Pathol 1998 Nov;15(4):285-99. PMID: 9845429

Recent clinical studies

Etiology

Cheng N, Ren Y, Zhou J, Zhang Y, Wang D, Zhang X, Chen B, Liu F, Lv J, Cao Q, Chen S, Du H, Hui D, Weng Z, Liang Q, Su B, Tang L, Han L, Chen J, Shao C
Gastroenterology 2022 Jun;162(7):1948-1961.e7. Epub 2022 Feb 22 doi: 10.1053/j.gastro.2022.02.025. PMID: 35202643
Desjonqueres E, Campani C, Marra F, Zucman-Rossi J, Nault JC
Liver Int 2022 Mar;42(3):492-506. Epub 2022 Jan 17 doi: 10.1111/liv.15152. PMID: 34982503
Fateen W, Johnson PJ, Wood HM, Zhang H, He S, El-Meteini M, Wyatt JI, Aithal GP, Quirke P
J Pathol 2021 Sep;255(1):30-40. Epub 2021 Jul 7 doi: 10.1002/path.5734. PMID: 34028025
Niu ZS, Niu XJ, Wang WH, Zhao J
World J Gastroenterol 2016 Mar 28;22(12):3305-14. doi: 10.3748/wjg.v22.i12.3305. PMID: 27022212Free PMC Article
Nault JC, Zucman-Rossi J
Clin Res Hepatol Gastroenterol 2016 Feb;40(1):9-14. Epub 2015 Aug 31 doi: 10.1016/j.clinre.2015.07.006. PMID: 26336998

Diagnosis

Cheng N, Ren Y, Zhou J, Zhang Y, Wang D, Zhang X, Chen B, Liu F, Lv J, Cao Q, Chen S, Du H, Hui D, Weng Z, Liang Q, Su B, Tang L, Han L, Chen J, Shao C
Gastroenterology 2022 Jun;162(7):1948-1961.e7. Epub 2022 Feb 22 doi: 10.1053/j.gastro.2022.02.025. PMID: 35202643
Desjonqueres E, Campani C, Marra F, Zucman-Rossi J, Nault JC
Liver Int 2022 Mar;42(3):492-506. Epub 2022 Jan 17 doi: 10.1111/liv.15152. PMID: 34982503
Yang Y, Liu C, Qi L, Zhao T, Feng Y, Ai X, Zhao X, Li J, Zhu Q
Dig Dis Sci 2020 Sep;65(9):2492-2502. Epub 2019 Dec 5 doi: 10.1007/s10620-019-05981-0. PMID: 31808004
Niu ZS, Niu XJ, Wang WH, Zhao J
World J Gastroenterol 2016 Mar 28;22(12):3305-14. doi: 10.3748/wjg.v22.i12.3305. PMID: 27022212Free PMC Article
Merkle EM, Zech CJ, Bartolozzi C, Bashir MR, Ba-Ssalamah A, Huppertz A, Lee JM, Ricke J, Sakamoto M, Sirlin CB, Ye SL, Zeng M
Eur Radiol 2016 Mar;26(3):674-82. Epub 2015 Jun 13 doi: 10.1007/s00330-015-3873-2. PMID: 26070500Free PMC Article

Therapy

Renzulli M, Braccischi L, D'Errico A, Pecorelli A, Brandi N, Golfieri R, Albertini E, Vasuri F
Histol Histopathol 2022 Dec;37(12):1151-1165. Epub 2022 Jun 30 doi: 10.14670/HH-18-487. PMID: 35770721
Yang Y, Liu C, Qi L, Zhao T, Feng Y, Ai X, Zhao X, Li J, Zhu Q
Dig Dis Sci 2020 Sep;65(9):2492-2502. Epub 2019 Dec 5 doi: 10.1007/s10620-019-05981-0. PMID: 31808004
Kim BR, Lee JM, Lee DH, Yoon JH, Hur BY, Suh KS, Yi NJ, Lee KB, Han JK
Radiology 2017 Oct;285(1):134-146. Epub 2017 Jun 13 doi: 10.1148/radiol.2017162080. PMID: 28609205
Kudo M
Oncology 2008;75 Suppl 1:1-12. Epub 2008 Dec 17 doi: 10.1159/000181865. PMID: 19092266
Kudo M
Clin Gastroenterol Hepatol 2005 Oct;3(10 Suppl 2):S144-8. doi: 10.1016/s1542-3565(05)00712-3. PMID: 16234064

Prognosis

Cheng N, Ren Y, Zhou J, Zhang Y, Wang D, Zhang X, Chen B, Liu F, Lv J, Cao Q, Chen S, Du H, Hui D, Weng Z, Liang Q, Su B, Tang L, Han L, Chen J, Shao C
Gastroenterology 2022 Jun;162(7):1948-1961.e7. Epub 2022 Feb 22 doi: 10.1053/j.gastro.2022.02.025. PMID: 35202643
Li YR, Chen JD, Zhu YY, Li JT, Jin GZ, Jin RM
Anticancer Drugs 2022 Jan 1;33(1):e500-e506. doi: 10.1097/CAD.0000000000001150. PMID: 34321420Free PMC Article
Yang Y, Liu C, Qi L, Zhao T, Feng Y, Ai X, Zhao X, Li J, Zhu Q
Dig Dis Sci 2020 Sep;65(9):2492-2502. Epub 2019 Dec 5 doi: 10.1007/s10620-019-05981-0. PMID: 31808004
Niu ZS, Niu XJ, Wang WH, Zhao J
World J Gastroenterol 2016 Mar 28;22(12):3305-14. doi: 10.3748/wjg.v22.i12.3305. PMID: 27022212Free PMC Article
Taouli B, Losada M, Holland A, Krinsky G
Gastroenterology 2004 Nov;127(5 Suppl 1):S144-52. doi: 10.1053/j.gastro.2004.09.028. PMID: 15508078

Clinical prediction guides

Cheng N, Ren Y, Zhou J, Zhang Y, Wang D, Zhang X, Chen B, Liu F, Lv J, Cao Q, Chen S, Du H, Hui D, Weng Z, Liang Q, Su B, Tang L, Han L, Chen J, Shao C
Gastroenterology 2022 Jun;162(7):1948-1961.e7. Epub 2022 Feb 22 doi: 10.1053/j.gastro.2022.02.025. PMID: 35202643
Li YR, Chen JD, Zhu YY, Li JT, Jin GZ, Jin RM
Anticancer Drugs 2022 Jan 1;33(1):e500-e506. doi: 10.1097/CAD.0000000000001150. PMID: 34321420Free PMC Article
Yang Y, Liu C, Qi L, Zhao T, Feng Y, Ai X, Zhao X, Li J, Zhu Q
Dig Dis Sci 2020 Sep;65(9):2492-2502. Epub 2019 Dec 5 doi: 10.1007/s10620-019-05981-0. PMID: 31808004
Jee BA, Choi JH, Rhee H, Yoon S, Kwon SM, Nahm JH, Yoo JE, Jeon Y, Choi GH, Woo HG, Park YN
Cancer Res 2019 Nov 1;79(21):5500-5512. Epub 2019 Sep 10 doi: 10.1158/0008-5472.CAN-19-0991. PMID: 31506333
Nault JC, Zucman-Rossi J
Clin Res Hepatol Gastroenterol 2016 Feb;40(1):9-14. Epub 2015 Aug 31 doi: 10.1016/j.clinre.2015.07.006. PMID: 26336998

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