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Bile Duct Intraductal Papillary Neoplasm, High Grade

MedGen UID:
474684
Concept ID:
C3273051
Neoplastic Process
Synonyms: Bile Duct Intraductal Papillary Neoplasm with High Grade Intraepithelial Neoplasia; Bile Duct Intraductal Papillary Neoplasm, High-Grade; Bile Duct IPN with High Grade Intraepithelial Neoplasia; Bile Duct Papillary Neoplasm with High Grade Intraepithelial Neoplasia; Intraductal Papillary Neoplasm with High Grade Intraepithelial Neoplasia; Intraductal papillary neoplasm with high grade intraepithelial neoplasia
SNOMED CT: Intraductal papillary neoplasm with high grade intraepithelial neoplasia (734133009)

Definition

An intraductal papillary neoplasm that arises from the epithelium of the intrahepatic or extrahepatic bile ducts. It is characterized by the presence of severe epithelial atypia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBile Duct Intraductal Papillary Neoplasm, High Grade

Recent clinical studies

Etiology

Pitman MB, Centeno BA, Reid MD, Saeig M, Siddiqui MT, Layfield LJ, Perez-Machado M, Weynand B, Stelow EB, Lozano MD, Fukushima N, Cree IA, Mehrotra R, Schmitt FC, Field AS
J Am Soc Cytopathol 2023 Jul-Aug;12(4):243-250. Epub 2023 Mar 7 doi: 10.1016/j.jasc.2023.03.002. PMID: 37003924
Pitman MB, Centeno BA, Reid MD, Siddiqui MT, Layfield LJ, Perez-Machado M, Weynand B, Stelow EB, Lozano MD, Fukushima N, Cree IA, Mehrotra R, Schmitt FC, Field AS
Acta Cytol 2023;67(3):304-320. Epub 2022 Dec 14 doi: 10.1159/000527912. PMID: 36516741
Stendahl K, Gilani SM, Basturk O, Hui P, Sigel C, Cai G
Cancer Cytopathol 2023 Jan;131(1):37-49. Epub 2022 Aug 30 doi: 10.1002/cncy.22637. PMID: 36041224Free PMC Article
Desjonqueres E, Campani C, Marra F, Zucman-Rossi J, Nault JC
Liver Int 2022 Mar;42(3):492-506. Epub 2022 Jan 17 doi: 10.1111/liv.15152. PMID: 34982503
Aslam A, Wasnik AP, Shi J, Sahai V, Mendiratta-Lala M
Clin Imaging 2020 Oct;66:10-17. Epub 2020 May 3 doi: 10.1016/j.clinimag.2020.04.036. PMID: 32438236Free PMC Article

Diagnosis

Mocchegiani F, Vincenzi P, Conte G, Nicolini D, Rossi R, Cacciaguerra AB, Vivarelli M
World J Gastroenterol 2023 Oct 14;29(38):5361-5373. doi: 10.3748/wjg.v29.i38.5361. PMID: 37900587Free PMC Article
Pitman MB, Centeno BA, Reid MD, Saeig M, Siddiqui MT, Layfield LJ, Perez-Machado M, Weynand B, Stelow EB, Lozano MD, Fukushima N, Cree IA, Mehrotra R, Schmitt FC, Field AS
J Am Soc Cytopathol 2023 Jul-Aug;12(4):243-250. Epub 2023 Mar 7 doi: 10.1016/j.jasc.2023.03.002. PMID: 37003924
Wang T, Askan G, Ozcan K, Rana S, Zehir A, Bhanot UK, Yantiss RK, Rao DS, Wahl SJ, Bagci P, Balci S, Balachandran V, Jarnagin WR, Adsay NV, Klimstra DS, Basturk O
Arch Pathol Lab Med 2023 Dec 1;147(12):1390-1401. doi: 10.5858/arpa.2022-0343-OA. PMID: 36821179
Pitman MB, Centeno BA, Reid MD, Siddiqui MT, Layfield LJ, Perez-Machado M, Weynand B, Stelow EB, Lozano MD, Fukushima N, Cree IA, Mehrotra R, Schmitt FC, Field AS
Acta Cytol 2023;67(3):304-320. Epub 2022 Dec 14 doi: 10.1159/000527912. PMID: 36516741
Stendahl K, Gilani SM, Basturk O, Hui P, Sigel C, Cai G
Cancer Cytopathol 2023 Jan;131(1):37-49. Epub 2022 Aug 30 doi: 10.1002/cncy.22637. PMID: 36041224Free PMC Article

Therapy

Höhn P, Braumann C, Munding J, Tannapfel A, Uhl W, Künzli BM
J Gastrointest Cancer 2019 Mar;50(1):160-169. doi: 10.1007/s12029-018-00199-1. PMID: 30628030

Prognosis

Mocchegiani F, Vincenzi P, Conte G, Nicolini D, Rossi R, Cacciaguerra AB, Vivarelli M
World J Gastroenterol 2023 Oct 14;29(38):5361-5373. doi: 10.3748/wjg.v29.i38.5361. PMID: 37900587Free PMC Article
Pitman MB, Centeno BA, Reid MD, Saeig M, Siddiqui MT, Layfield LJ, Perez-Machado M, Weynand B, Stelow EB, Lozano MD, Fukushima N, Cree IA, Mehrotra R, Schmitt FC, Field AS
J Am Soc Cytopathol 2023 Jul-Aug;12(4):243-250. Epub 2023 Mar 7 doi: 10.1016/j.jasc.2023.03.002. PMID: 37003924
Pitman MB, Centeno BA, Reid MD, Siddiqui MT, Layfield LJ, Perez-Machado M, Weynand B, Stelow EB, Lozano MD, Fukushima N, Cree IA, Mehrotra R, Schmitt FC, Field AS
Acta Cytol 2023;67(3):304-320. Epub 2022 Dec 14 doi: 10.1159/000527912. PMID: 36516741
Youn JM, Hwang S, Ahn CS, Moon DB, Ha TY, Song GW, Jung DH, Hong SM
J Gastrointest Surg 2022 Jul;26(7):1394-1405. Epub 2022 Feb 9 doi: 10.1007/s11605-022-05268-2. PMID: 35141839
Sakai Y, Ohtsuka M, Sugiyama H, Mikata R, Yasui S, Ohno I, Iino Y, Kato J, Tsuyuguchi T, Kato N
World J Gastroenterol 2021 Apr 21;27(15):1569-1577. doi: 10.3748/wjg.v27.i15.1569. PMID: 33958844Free PMC Article

Clinical prediction guides

Kubo S, Tanaka S, Kinoshita M, Shinkawa H, Ishizawa T, Sato Y
Virchows Arch 2023 Apr;482(4):745-753. Epub 2023 Jan 30 doi: 10.1007/s00428-023-03499-5. PMID: 36715769
Nakanuma Y, Uesaka K, Okamura Y, Terada T, Fukumura Y, Kakuda Y, Sugino T, Sato Y, Taek JK, Park YN
Hum Pathol 2021 May;111:21-35. Epub 2021 Jan 27 doi: 10.1016/j.humpath.2021.01.002. PMID: 33508254
Aslam A, Wasnik AP, Shi J, Sahai V, Mendiratta-Lala M
Clin Imaging 2020 Oct;66:10-17. Epub 2020 May 3 doi: 10.1016/j.clinimag.2020.04.036. PMID: 32438236Free PMC Article
Akita M, Hong SM, Sung YN, Kim MJ, Ajiki T, Fukumoto T, Itoh T, Zen Y
Histopathology 2020 Jun;76(7):1005-1012. Epub 2020 May 15 doi: 10.1111/his.14103. PMID: 32181510
Naito Y, Kusano H, Nakashima O, Sadashima E, Hattori S, Taira T, Kawahara A, Okabe Y, Shimamatsu K, Taguchi J, Momosaki S, Irie K, Yamaguchi R, Yokomizo H, Nagamine M, Fukuda S, Sugiyama S, Nishida N, Higaki K, Yoshitomi M, Yasunaga M, Okuda K, Kinoshita H, Nakayama M, Yasumoto M, Akiba J, Kage M, Yano H
World J Gastroenterol 2012 Jul 28;18(28):3673-80. doi: 10.3748/wjg.v18.i28.3673. PMID: 22851859Free PMC Article

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