U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Liver Germ Cell Tumor

MedGen UID:
474710
Concept ID:
C3273077
Neoplastic Process
Synonym: Hepatic Germ Cell Tumor

Definition

A benign or malignant extragonadal germ cell tumor that arises from the liver. Representative examples include teratoma and yolk sac tumor. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLiver Germ Cell Tumor

Professional guidelines

PubMed

Carvajal RD, Sacco JJ, Jager MJ, Eschelman DJ, Olofsson Bagge R, Harbour JW, Chieng ND, Patel SP, Joshua AM, Piperno-Neumann S
Nat Rev Clin Oncol 2023 Feb;20(2):99-115. Epub 2023 Jan 4 doi: 10.1038/s41571-022-00714-1. PMID: 36600005
Gallo C, Rossi RE, Cavalcoli F, Barbaro F, Boškoski I, Invernizzi P, Massironi S
World J Gastroenterol 2022 Mar 21;28(11):1123-1138. doi: 10.3748/wjg.v28.i11.1123. PMID: 35431507Free PMC Article
Spain L, Diem S, Larkin J
Cancer Treat Rev 2016 Mar;44:51-60. Epub 2016 Feb 6 doi: 10.1016/j.ctrv.2016.02.001. PMID: 26874776

Recent clinical studies

Etiology

Gallo C, Rossi RE, Cavalcoli F, Barbaro F, Boškoski I, Invernizzi P, Massironi S
World J Gastroenterol 2022 Mar 21;28(11):1123-1138. doi: 10.3748/wjg.v28.i11.1123. PMID: 35431507Free PMC Article
Mete O, Asa SL, Gill AJ, Kimura N, de Krijger RR, Tischler A
Endocr Pathol 2022 Mar;33(1):90-114. Epub 2022 Mar 13 doi: 10.1007/s12022-022-09704-6. PMID: 35285002
Perri G, Prakash LR, Katz MHG
Curr Opin Gastroenterol 2019 Sep;35(5):468-477. doi: 10.1097/MOG.0000000000000571. PMID: 31306159
Weber JS, Kähler KC, Hauschild A
J Clin Oncol 2012 Jul 20;30(21):2691-7. Epub 2012 May 21 doi: 10.1200/JCO.2012.41.6750. PMID: 22614989
J Clin Oncol 1997 Feb;15(2):594-603. doi: 10.1200/JCO.1997.15.2.594. PMID: 9053482

Diagnosis

Shah A, Nassiri N, Daneshmand S
Curr Opin Urol 2019 Jan;29(1):33-41. doi: 10.1097/MOU.0000000000000563. PMID: 30334834
Medina A, Ramos M, Amenedo M, París L
Arch Esp Urol 2014 Oct;67(8):711-4. PMID: 25306991
Orbach D, Sarnacki S, Brisse HJ, Gauthier-Villars M, Jarreau PH, Tsatsaris V, Baruchel A, Zerah M, Seigneur E, Peuchmaur M, Doz F
Lancet Oncol 2013 Dec;14(13):e609-20. doi: 10.1016/S1470-2045(13)70236-5. PMID: 24275134
Halperin EC
Int J Radiat Oncol Biol Phys 2000 Apr 1;47(1):171-8. doi: 10.1016/s0360-3016(00)00424-7. PMID: 10758320
Raven RW
Ann R Coll Surg Engl 1975 Feb;56(2):89-93. PMID: 1119786Free PMC Article

Therapy

Song Q, Zhang X, Liu W, Wei H, Liang W, Zhou Y, Ding Y, Ji F, Ho-Kwan Cheung A, Wong N, Yu J
J Hepatol 2023 Dec;79(6):1352-1365. Epub 2023 Jul 17 doi: 10.1016/j.jhep.2023.07.005. PMID: 37459922
Wang Y, Chen C, Chen J, Sang T, Peng H, Lin X, Zhao Q, Chen S, Eling T, Wang X
Redox Biol 2022 Jun;52:102322. Epub 2022 Apr 27 doi: 10.1016/j.redox.2022.102322. PMID: 35504134Free PMC Article
Rantala ES, Hernberg MM, Piperno-Neumann S, Grossniklaus HE, Kivelä TT
Prog Retin Eye Res 2022 Sep;90:101041. Epub 2022 Jan 6 doi: 10.1016/j.preteyeres.2022.101041. PMID: 34999237
Cives M, Strosberg JR
CA Cancer J Clin 2018 Nov;68(6):471-487. Epub 2018 Oct 8 doi: 10.3322/caac.21493. PMID: 30295930
J Clin Oncol 1997 Feb;15(2):594-603. doi: 10.1200/JCO.1997.15.2.594. PMID: 9053482

Prognosis

Tripathi PR, Sen Sarma M, Srivastava A
Dig Liver Dis 2022 Feb;54(2):282. Epub 2020 Oct 26 doi: 10.1016/j.dld.2020.10.004. PMID: 33115626
Patrinely JR Jr, Johnson R, Lawless AR, Bhave P, Sawyers A, Dimitrova M, Yeoh HL, Palmeri M, Ye F, Fan R, Davis EJ, Rapisuwon S, Long GV, Haydon A, Osman I, Mehnert JM, Carlino MS, Sullivan RJ, Menzies AM, Johnson DB
JAMA Oncol 2021 May 1;7(5):744-748. doi: 10.1001/jamaoncol.2021.0051. PMID: 33764387Free PMC Article
Asa SL, Mete O
Pathology 2018 Jan;50(1):111-118. Epub 2017 Nov 11 doi: 10.1016/j.pathol.2017.09.003. PMID: 29132721
von Schweinitz D
Semin Neonatol 2003 Oct;8(5):403-10. doi: 10.1016/S1084-2756(03)00092-7. PMID: 15001128
J Clin Oncol 1997 Feb;15(2):594-603. doi: 10.1200/JCO.1997.15.2.594. PMID: 9053482

Clinical prediction guides

Song Q, Zhang X, Liu W, Wei H, Liang W, Zhou Y, Ding Y, Ji F, Ho-Kwan Cheung A, Wong N, Yu J
J Hepatol 2023 Dec;79(6):1352-1365. Epub 2023 Jul 17 doi: 10.1016/j.jhep.2023.07.005. PMID: 37459922
Mete O, Asa SL, Gill AJ, Kimura N, de Krijger RR, Tischler A
Endocr Pathol 2022 Mar;33(1):90-114. Epub 2022 Mar 13 doi: 10.1007/s12022-022-09704-6. PMID: 35285002
Bellizzi AM
Hum Pathol 2020 Feb;96:8-33. Epub 2019 Dec 17 doi: 10.1016/j.humpath.2019.12.002. PMID: 31857137Free PMC Article
Perri G, Prakash LR, Katz MHG
Curr Opin Gastroenterol 2019 Sep;35(5):468-477. doi: 10.1097/MOG.0000000000000571. PMID: 31306159
Weber JS, Kähler KC, Hauschild A
J Clin Oncol 2012 Jul 20;30(21):2691-7. Epub 2012 May 21 doi: 10.1200/JCO.2012.41.6750. PMID: 22614989

Recent systematic reviews

Harrelson A, Wang R, Stewart A, Ingram C, Gillis A, Rose JB, El-Rayes B, Azmi A, Chen H
Am J Surg 2023 Nov;226(5):623-630. Epub 2023 Aug 16 doi: 10.1016/j.amjsurg.2023.08.011. PMID: 37657968
Khazzaka A, Rassy E, Sleiman Z, Boussios S, Pavlidis N
Cancer Treat Rev 2022 Mar;104:102356. Epub 2022 Feb 11 doi: 10.1016/j.ctrv.2022.102356. PMID: 35182890
Duchateau NM, Canovai E, Vianna RM, Vanuytsel T, Verslype C, Mazariegos GV, Monbaliu D, Pirenne J, Ceulemans LJ
Transplant Rev (Orlando) 2022 Jan;36(1):100678. Epub 2022 Jan 21 doi: 10.1016/j.trre.2022.100678. PMID: 35090785
Guo J, Zhang Q, Bi X, Zhou J, Li Z, Huang Z, Zhang Y, Li M, Chen X, Hu X, Yihebali C, Liang J, Liu J, Zhao J, Cai J, Zhao H
Oncotarget 2017 Mar 7;8(10):17396-17405. doi: 10.18632/oncotarget.14156. PMID: 28030811Free PMC Article
Fan ST, Le Treut YP, Mazzaferro V, Burroughs AK, Olausson M, Breitenstein S, Frilling A
HPB (Oxford) 2015 Jan;17(1):23-8. Epub 2014 Jul 3 doi: 10.1111/hpb.12308. PMID: 24992381Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...