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Gallbladder Cribriform Carcinoma

MedGen UID:
474736
•Concept ID:
C3273103
•
Neoplastic Process

Definition

A rare variant of gallbladder adenocarcinoma. It is characterized by the presence of a malignant glandular epithelial infiltrate with a cribriform growth pattern. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGallbladder Cribriform Carcinoma

Professional guidelines

PubMed

Biliary tract cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Vogel A, Bridgewater J, Edeline J, Kelley RK, Klümpen HJ, Malka D, Primrose JN, Rimassa L, Stenzinger A, Valle JW, Ducreux M; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Feb;34(2):127-140. Epub 2022 Nov 10 doi: 10.1016/j.annonc.2022.10.506. PMID: 36372281
Hepatobiliary Cancers, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Benson AB, D'Angelica MI, Abbott DE, Anaya DA, Anders R, Are C, Bachini M, Borad M, Brown D, Burgoyne A, Chahal P, Chang DT, Cloyd J, Covey AM, Glazer ES, Goyal L, Hawkins WG, Iyer R, Jacob R, Kelley RK, Kim R, Levine M, Palta M, Park JO, Raman S, Reddy S, Sahai V, Schefter T, Singh G, Stein S, Vauthey JN, Venook AP, Yopp A, McMillian NR, Hochstetler C, Darlow SD
J Natl Compr Canc Netw 2021 May 1;19(5):541-565. doi: 10.6004/jnccn.2021.0022. PMID: 34030131
Gallbladder adenomyomatosis: Diagnosis and management.
Golse N, Lewin M, Rode A, Sebagh M, Mabrut JY
J Visc Surg 2017 Oct;154(5):345-353. Epub 2017 Aug 24 doi: 10.1016/j.jviscsurg.2017.06.004. PMID: 28844704

Recent clinical studies

Etiology

Differential and prognostic MRI features of gallbladder neuroendocrine tumors and adenocarcinomas.
Bae JS, Kim SH, Yoo J, Kim H, Han JK
Eur Radiol 2020 May;30(5):2890-2901. Epub 2020 Feb 5 doi: 10.1007/s00330-019-06588-9. PMID: 32025835
Dysplasia in Gallbladder: What Should We Do?
Rais R, González I, Chatterjee D
J Gastrointest Surg 2019 Apr;23(4):686-689. Epub 2018 Sep 13 doi: 10.1007/s11605-018-3955-y. PMID: 30215198
Significance of HER2 and Ki-67 in Preneoplastic Lesions and Carcinoma of Gallbladder.
Halder S, Kundu S, Chakraborty J, Chakrabarti S
J Gastrointest Cancer 2019 Dec;50(4):848-854. doi: 10.1007/s12029-018-0162-8. PMID: 30155833
Gallbladder cancer, treatment failure and relapses: the peritoneum in gallbladder cancer.
Maplanka C
J Gastrointest Cancer 2014 Sep;45(3):245-55. doi: 10.1007/s12029-014-9597-8. PMID: 24652122
Diagnostic and management issues in gallbladder carcinoma.
Abi-Rached B, Neugut AI
Oncology (Williston Park) 1995 Jan;9(1):19-24; discussion 24, 27, 30. PMID: 7718438

Diagnosis

Gallbladder microbiota composition is associated with pancreaticobiliary and gallbladder cancer prognosis.
Kirishima M, Yokoyama S, Matsuo K, Hamada T, Shimokawa M, Akahane T, Sugimoto T, Tsurumaru H, Ishibashi M, Mataki Y, Ootsuka T, Nomoto M, Hayashi C, Horiguchi A, Higashi M, Tanimoto A
BMC Microbiol 2022 May 27;22(1):147. doi: 10.1186/s12866-022-02557-3. PMID: 35624429Free PMC Article
Neuroendocrine Carcinoma of the Gallbladder.
Sharma A, Saluja SS, Nag HH, Sharma M, Sakhuja P
Am Surg 2022 Nov;88(11):2768-2770. Epub 2020 Sep 16 doi: 10.1177/0003134820951466. PMID: 32935998
Dysplasia in Gallbladder: What Should We Do?
Rais R, González I, Chatterjee D
J Gastrointest Surg 2019 Apr;23(4):686-689. Epub 2018 Sep 13 doi: 10.1007/s11605-018-3955-y. PMID: 30215198
Liver fibrosis, cirrhosis, and cirrhosis-related nodules: Imaging diagnosis and surveillance.
Aubé C, Bazeries P, Lebigot J, Cartier V, Boursier J
Diagn Interv Imaging 2017 Jun;98(6):455-468. Epub 2017 Apr 29 doi: 10.1016/j.diii.2017.03.003. PMID: 28461073
The gallbladder: uncommon gallbladder conditions and unusual presentations of the common gallbladder pathological processes.
Revzin MV, Scoutt L, Smitaman E, Israel GM
Abdom Imaging 2015 Feb;40(2):385-99. doi: 10.1007/s00261-014-0203-0. PMID: 25063238

Therapy

Current and emerging therapies for advanced biliary tract cancers.
Kam AE, Masood A, Shroff RT
Lancet Gastroenterol Hepatol 2021 Nov;6(11):956-969. doi: 10.1016/S2468-1253(21)00171-0. PMID: 34626563
Hepatobiliary Cancers, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Benson AB, D'Angelica MI, Abbott DE, Anaya DA, Anders R, Are C, Bachini M, Borad M, Brown D, Burgoyne A, Chahal P, Chang DT, Cloyd J, Covey AM, Glazer ES, Goyal L, Hawkins WG, Iyer R, Jacob R, Kelley RK, Kim R, Levine M, Palta M, Park JO, Raman S, Reddy S, Sahai V, Schefter T, Singh G, Stein S, Vauthey JN, Venook AP, Yopp A, McMillian NR, Hochstetler C, Darlow SD
J Natl Compr Canc Netw 2021 May 1;19(5):541-565. doi: 10.6004/jnccn.2021.0022. PMID: 34030131
Molecular targeted therapies: Ready for "prime time" in biliary tract cancer.
Lamarca A, Barriuso J, McNamara MG, Valle JW
J Hepatol 2020 Jul;73(1):170-185. Epub 2020 Mar 12 doi: 10.1016/j.jhep.2020.03.007. PMID: 32171892
Cholangiocarcinoma.
Squadroni M, Tondulli L, Gatta G, Mosconi S, Beretta G, Labianca R
Crit Rev Oncol Hematol 2017 Aug;116:11-31. Epub 2016 Nov 25 doi: 10.1016/j.critrevonc.2016.11.012. PMID: 28693792
SWOG S0809: A Phase II Intergroup Trial of Adjuvant Capecitabine and Gemcitabine Followed by Radiotherapy and Concurrent Capecitabine in Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma.
Ben-Josef E, Guthrie KA, El-Khoueiry AB, Corless CL, Zalupski MM, Lowy AM, Thomas CR Jr, Alberts SR, Dawson LA, Micetich KC, Thomas MB, Siegel AB, Blanke CD
J Clin Oncol 2015 Aug 20;33(24):2617-22. Epub 2015 May 11 doi: 10.1200/JCO.2014.60.2219. PMID: 25964250Free PMC Article

Prognosis

Neuroendocrine neoplasm of the gallbladder: Clinical features, surgical efficacy, and prognosis.
Wu X, Li B, Hong T, Liu W, He X, Zheng C
Cancer Med 2023 May;12(10):11344-11350. Epub 2023 Mar 23 doi: 10.1002/cam4.5846. PMID: 36952352Free PMC Article
Gallbladder microbiota composition is associated with pancreaticobiliary and gallbladder cancer prognosis.
Kirishima M, Yokoyama S, Matsuo K, Hamada T, Shimokawa M, Akahane T, Sugimoto T, Tsurumaru H, Ishibashi M, Mataki Y, Ootsuka T, Nomoto M, Hayashi C, Horiguchi A, Higashi M, Tanimoto A
BMC Microbiol 2022 May 27;22(1):147. doi: 10.1186/s12866-022-02557-3. PMID: 35624429Free PMC Article
Clinicopathological characteristics and prognosis of signet ring cell carcinoma of the gallbladder.
Wang S, Li J, You J, Zhou Y
BMC Gastroenterol 2021 Jun 6;21(1):248. doi: 10.1186/s12876-021-01831-4. PMID: 34090347Free PMC Article
Characteristics and survival prognosis of patients with pure squamous cell carcinoma of the gallbladder.
Zhu C, Sun L, Wei Y, Xu D, Zhou Y
ANZ J Surg 2021 Mar;91(3):E91-E97. Epub 2020 Nov 24 doi: 10.1111/ans.16452. PMID: 33236449
Gallbladder cancer, treatment failure and relapses: the peritoneum in gallbladder cancer.
Maplanka C
J Gastrointest Cancer 2014 Sep;45(3):245-55. doi: 10.1007/s12029-014-9597-8. PMID: 24652122

Clinical prediction guides

High intramuscular adipose tissue content associated with prognosis and postoperative complications of cancers.
Liu R, Qiu Z, Zhang L, Ma W, Zi L, Wang K, Kuang T, Zhao K, Wang W
J Cachexia Sarcopenia Muscle 2023 Dec;14(6):2509-2519. Epub 2023 Nov 22 doi: 10.1002/jcsm.13371. PMID: 37990969Free PMC Article
Current and emerging therapies for advanced biliary tract cancers.
Kam AE, Masood A, Shroff RT
Lancet Gastroenterol Hepatol 2021 Nov;6(11):956-969. doi: 10.1016/S2468-1253(21)00171-0. PMID: 34626563
Assessment of Textbook Outcome in Laparoscopic and Open Liver Surgery.
Görgec B, Benedetti Cacciaguerra A, Lanari J, Russolillo N, Cipriani F, Aghayan D, Zimmitti G, Efanov M, Alseidi A, Mocchegiani F, Giuliante F, Ruzzenente A, Rotellar F, Fuks D, D'Hondt M, Vivarelli M, Edwin B, Aldrighetti LA, Ferrero A, Cillo U, Besselink MG, Abu Hilal M
JAMA Surg 2021 Aug 1;156(8):e212064. Epub 2021 Aug 11 doi: 10.1001/jamasurg.2021.2064. PMID: 34076671Free PMC Article
Update in clinical management for gallbladder neuroendocrine carcinoma.
Chu H, Shi Y, Liu J, Huang D, Zhang J, Dou C
Medicine (Baltimore) 2021 Apr 9;100(14):e25449. doi: 10.1097/MD.0000000000025449. PMID: 33832150Free PMC Article
Significance of HER2 and Ki-67 in Preneoplastic Lesions and Carcinoma of Gallbladder.
Halder S, Kundu S, Chakraborty J, Chakrabarti S
J Gastrointest Cancer 2019 Dec;50(4):848-854. doi: 10.1007/s12029-018-0162-8. PMID: 30155833

Recent systematic reviews

High intramuscular adipose tissue content associated with prognosis and postoperative complications of cancers.
Liu R, Qiu Z, Zhang L, Ma W, Zi L, Wang K, Kuang T, Zhao K, Wang W
J Cachexia Sarcopenia Muscle 2023 Dec;14(6):2509-2519. Epub 2023 Nov 22 doi: 10.1002/jcsm.13371. PMID: 37990969Free PMC Article
The present roles and future perspectives of Interleukin-6 in biliary tract cancer.
Zhou M, Na R, Lai S, Guo Y, Shi J, Nie J, Zhang S, Wang Y, Zheng T
Cytokine 2023 Sep;169:156271. Epub 2023 Jun 16 doi: 10.1016/j.cyto.2023.156271. PMID: 37331095
Systematic review of squamous cell carcinoma of the gallbladder.
Takahashi H, Irri A, Fenig Y, Byale A, Thung S, Gunasekaran G
Am J Surg 2022 Sep;224(3):863-868. Epub 2022 Apr 23 doi: 10.1016/j.amjsurg.2022.04.024. PMID: 35483997
Postoperative adjuvant chemotherapy for resectable cholangiocarcinoma.
Luvira V, Satitkarnmanee E, Pugkhem A, Kietpeerakool C, Lumbiganon P, Pattanittum P
Cochrane Database Syst Rev 2021 Sep 13;9(9):CD012814. doi: 10.1002/14651858.CD012814.pub2. PMID: 34515993Free PMC Article
Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies.
Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M
Lancet 2008 Feb 16;371(9612):569-78. doi: 10.1016/S0140-6736(08)60269-X. PMID: 18280327

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