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Extrahepatic Bile Duct Neuroendocrine Tumor

MedGen UID:
474772
Concept ID:
C3273139
Neoplastic Process
Synonyms: Extrahepatic Bile Duct NET; Extrahepatic Bile Duct Well Differentiated Endocrine Tumor; Extrahepatic Bile Duct Well Differentiated Endocrine Tumor/Carcinoma

Definition

A well differentiated, low, intermediate, or high grade neoplasm with neuroendocrine differentiation that arises from the extrahepatic bile ducts. [from NCI]

Professional guidelines

PubMed

Komiyama S, Okusaka T, Maruki Y, Ohba A, Nagashio Y, Kondo S, Hijioka S, Morizane C, Ueno H, Sukeda A, Mizui T, Takamoto T, Nara S, Ban D, Esaki M, Hiraoka N, Shimada K
Intern Med 2024 Apr 1;63(7):891-901. Epub 2023 Aug 23 doi: 10.2169/internalmedicine.2016-23. PMID: 37612088Free PMC Article
Zhu J, Xiao W, Li Y
J Laparoendosc Adv Surg Tech A 2022 Jun;32(6):639-645. Epub 2021 Oct 11 doi: 10.1089/lap.2021.0482. PMID: 34637632
O'Grady JG
Liver Transpl 2000 Nov;6(6 Suppl 2):S23-9. doi: 10.1053/jlts.2000.18687. PMID: 11084081

Recent clinical studies

Etiology

Karam E, Hollenbach M, Abou Ali E, Auriemma F, Anderloni A, Barbier L, Belfiori G, Caillol F, Crippa S, Del Chiaro M, De Ponthaud C, Dahel Y, Falconi M, Giovannini M, Heling D, Inoue Y, Jarnagin WR, Leung G, Lupinacci RM, Mariani A, Masaryk V, Miksch RC, Musquer N, Napoleon B, Oba A, Partelli S, Petrone MC, Prat F, Repici A, Sauvanet A, Salzmann K, Schattner MA, Schulick R, Schwarz L, Soares K, Souche FR, Truant S, Vaillant JC, Wang T, Wedi E, Werner J, Weismüller TJ, Wichmann D, Will U, Zaccari P, Gulla A, Heise C, Regner S, Gaujoux S; Pancreas 2000 Research Group
Neuroendocrinology 2023;113(10):1024-1034. Epub 2023 Jun 27 doi: 10.1159/000531712. PMID: 37369186
Nakaya M, Kurokawa R, Watadani T, Morisaka H, Higuchi M, Toda Y, Kunichika H, Kusakabe M, Okada Y, Ohgiya Y, Okada M, Anai H, Abe O, Minami M
Abdom Radiol (NY) 2022 Jun;47(6):1917-1928. Epub 2022 Apr 30 doi: 10.1007/s00261-022-03524-2. PMID: 35488897
Zhu J, Xiao W, Li Y
J Laparoendosc Adv Surg Tech A 2022 Jun;32(6):639-645. Epub 2021 Oct 11 doi: 10.1089/lap.2021.0482. PMID: 34637632
Luchini C, Pelosi G, Scarpa A, Mattiolo P, Marchiori D, Maragliano R, Sessa F, Uccella S
Pathologica 2021 Feb;113(1):28-38. doi: 10.32074/1591-951X-231. PMID: 33686308Free PMC Article
Hong N, Kim HJ, Byun JH, Kim SY, Kim KW, Kim JH, Hong SM
Abdom Imaging 2015 Jan;40(1):181-91. doi: 10.1007/s00261-014-0191-0. PMID: 25008023

Diagnosis

Luchini C, Pelosi G, Scarpa A, Mattiolo P, Marchiori D, Maragliano R, Sessa F, Uccella S
Pathologica 2021 Feb;113(1):28-38. doi: 10.32074/1591-951X-231. PMID: 33686308Free PMC Article
Umezaki N, Hashimoto D, Yamashita YI, Nakagawa S, Nakao Y, Itoyama R, Yusa T, Yamao T, Okabe H, Imai K, Hayashi H, Chikamoto A, Baba H
Anticancer Res 2019 Feb;39(2):903-907. doi: 10.21873/anticanres.13192. PMID: 30711974
Hong N, Kim HJ, Byun JH, Kim SY, Kim KW, Kim JH, Hong SM
Abdom Imaging 2015 Jan;40(1):181-91. doi: 10.1007/s00261-014-0191-0. PMID: 25008023
Michalopoulos N, Papavramidis TS, Karayannopoulou G, Pliakos I, Papavramidis ST, Kanellos I
Pathol Oncol Res 2014 Oct;20(4):765-75. Epub 2014 Jun 11 doi: 10.1007/s12253-014-9808-4. PMID: 24917351
Sasatomi E, Nalesnik MA, Marsh JW
World J Gastroenterol 2013 Jul 28;19(28):4616-23. doi: 10.3748/wjg.v19.i28.4616. PMID: 23901240Free PMC Article

Therapy

Fukasawa H, Tounou S, Nabetani M, Michida T
Intern Med 2017;56(5):499-503. Epub 2017 Mar 1 doi: 10.2169/internalmedicine.56.7520. PMID: 28250294Free PMC Article
Ravaioli M, Ercolani G, Neri F, Cescon M, Stacchini G, Del Gaudio M, Cucchetti A, Pinna AD
World J Gastroenterol 2014 May 14;20(18):5345-52. doi: 10.3748/wjg.v20.i18.5345. PMID: 24833864Free PMC Article
Snady H
Hematol Oncol Clin North Am 2002 Feb;16(1):53-79. doi: 10.1016/s0889-8588(01)00010-7. PMID: 12063829
Mantke R, Manger T, Schulz HU, Ridwelski K, Pross M, Günther T, Lippert H
Dig Surg 1999;16(2):145-51. doi: 10.1159/000018708. PMID: 10207242
Welch CE
N Engl J Med 1969 Feb 20;280(8):419-25 contd. doi: 10.1056/NEJM196902202800805. PMID: 4883944

Prognosis

Karam E, Hollenbach M, Abou Ali E, Auriemma F, Anderloni A, Barbier L, Belfiori G, Caillol F, Crippa S, Del Chiaro M, De Ponthaud C, Dahel Y, Falconi M, Giovannini M, Heling D, Inoue Y, Jarnagin WR, Leung G, Lupinacci RM, Mariani A, Masaryk V, Miksch RC, Musquer N, Napoleon B, Oba A, Partelli S, Petrone MC, Prat F, Repici A, Sauvanet A, Salzmann K, Schattner MA, Schulick R, Schwarz L, Soares K, Souche FR, Truant S, Vaillant JC, Wang T, Wedi E, Werner J, Weismüller TJ, Wichmann D, Will U, Zaccari P, Gulla A, Heise C, Regner S, Gaujoux S; Pancreas 2000 Research Group
Neuroendocrinology 2023;113(10):1024-1034. Epub 2023 Jun 27 doi: 10.1159/000531712. PMID: 37369186
Luchini C, Scarpa A
Hum Pathol 2023 Feb;132:176-182. Epub 2022 Jun 14 doi: 10.1016/j.humpath.2022.06.009. PMID: 35714836
Zhu J, Xiao W, Li Y
J Laparoendosc Adv Surg Tech A 2022 Jun;32(6):639-645. Epub 2021 Oct 11 doi: 10.1089/lap.2021.0482. PMID: 34637632
Michalopoulos N, Papavramidis TS, Karayannopoulou G, Pliakos I, Papavramidis ST, Kanellos I
Pathol Oncol Res 2014 Oct;20(4):765-75. Epub 2014 Jun 11 doi: 10.1007/s12253-014-9808-4. PMID: 24917351
Hartel M, Wente MN, Sido B, Friess H, Büchler MW
J Gastroenterol Hepatol 2005 May;20(5):676-81. doi: 10.1111/j.1440-1746.2005.03744.x. PMID: 15853978

Clinical prediction guides

Karam E, Hollenbach M, Abou Ali E, Auriemma F, Anderloni A, Barbier L, Belfiori G, Caillol F, Crippa S, Del Chiaro M, De Ponthaud C, Dahel Y, Falconi M, Giovannini M, Heling D, Inoue Y, Jarnagin WR, Leung G, Lupinacci RM, Mariani A, Masaryk V, Miksch RC, Musquer N, Napoleon B, Oba A, Partelli S, Petrone MC, Prat F, Repici A, Sauvanet A, Salzmann K, Schattner MA, Schulick R, Schwarz L, Soares K, Souche FR, Truant S, Vaillant JC, Wang T, Wedi E, Werner J, Weismüller TJ, Wichmann D, Will U, Zaccari P, Gulla A, Heise C, Regner S, Gaujoux S; Pancreas 2000 Research Group
Neuroendocrinology 2023;113(10):1024-1034. Epub 2023 Jun 27 doi: 10.1159/000531712. PMID: 37369186
Luchini C, Scarpa A
Hum Pathol 2023 Feb;132:176-182. Epub 2022 Jun 14 doi: 10.1016/j.humpath.2022.06.009. PMID: 35714836
Zheng BH, Zhang C, Wan WZ, Sun WT, Cheng X, Ni XJ, Ni XL, Suo T, Liu H, Shen S, Liu HB
BMC Surg 2022 Jun 29;22(1):253. doi: 10.1186/s12893-022-01689-7. PMID: 35768809Free PMC Article
Schmocker RK, Wright MJ, Ding D, Javed AA, Cameron JL, Lafaro K, Burns WR, He J, Wolfgang CL, Burkhart RA
J Surg Oncol 2021 Feb;123(2):416-424. Epub 2020 Oct 30 doi: 10.1002/jso.26285. PMID: 33125737
Hong N, Kim HJ, Byun JH, Kim SY, Kim KW, Kim JH, Hong SM
Abdom Imaging 2015 Jan;40(1):181-91. doi: 10.1007/s00261-014-0191-0. PMID: 25008023

Recent systematic reviews

Ziogas IA, Rallis KS, Tasoudis PT, Moris D, Schulick RD, Del Chiaro M
Eur J Surg Oncol 2023 Apr;49(4):682-687. Epub 2023 Jan 9 doi: 10.1016/j.ejso.2023.01.005. PMID: 36646615
Giannakodimos I, Giannakodimos A, Ziogou A, Frountzas M, Kritikos N, Vlachos K, Toutouzas KG, Schizas D
J Gastrointestin Liver Dis 2022 Dec 17;31(4):459-466. doi: 10.15403/jgld-4383. PMID: 36535044
Beger HG, Mayer B, Rau BM
J Gastrointest Surg 2016 Jan;20(1):206-17. Epub 2015 Nov 2 doi: 10.1007/s11605-015-2981-2. PMID: 26525207
Beger HG, Nakao A, Mayer B, Poch B
Pancreatology 2015 Mar-Apr;15(2):167-78. Epub 2015 Feb 7 doi: 10.1016/j.pan.2015.01.009. PMID: 25732271
Michalopoulos N, Papavramidis TS, Karayannopoulou G, Pliakos I, Papavramidis ST, Kanellos I
Pathol Oncol Res 2014 Oct;20(4):765-75. Epub 2014 Jun 11 doi: 10.1007/s12253-014-9808-4. PMID: 24917351

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