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Gastric enterochromaffin cell serotonin-producing neuroendocrine tumor

MedGen UID:
475770
•Concept ID:
C3274137
•
Neoplastic Process
Synonyms: Gastric EC Cell Serotonin-Producing NET; gastric EC cell serotonin-producing NET; Gastric EC-Cell Serotonin-Producing Neuroendocrine Tumor; gastric EC-cell serotonin-producing neuroendocrine tumor; gastric EC-cell serotonin-producing neuroendocrine tumour; Gastric Enterochromaffin Cell Serotonin-Producing Neuroendocrine Tumor; gastric enterochromaffin cell serotonin-producing neuroendocrine tumor
 
Monarch Initiative: MONDO:0024639

Definition

A well differentiated neuroendocrine tumor that arises from the stomach. It produces serotonin and it may occasionally be found in association with a carcinoid syndrome. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGastric enterochromaffin cell serotonin-producing neuroendocrine tumor

Recent clinical studies

Etiology

Vascular endothelial growth factors, angiogenesis, and survival in human ileal enterochromaffin cell carcinoids.
Besig S, Voland P, Baur DM, Perren A, Prinz C
Neuroendocrinology 2009;90(4):402-15. Epub 2009 Oct 8 doi: 10.1159/000245900. PMID: 19816005
From the archives of the AFIP: Gastrointestinal carcinoids: imaging features with clinicopathologic comparison.
Levy AD, Sobin LH
Radiographics 2007 Jan-Feb;27(1):237-57. doi: 10.1148/rg.271065169. PMID: 17235010

Diagnosis

Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas.
Leja J, Essaghir A, Essand M, Wester K, Oberg K, Tötterman TH, Lloyd R, Vasmatzis G, Demoulin JB, Giandomenico V
Mod Pathol 2009 Feb;22(2):261-72. Epub 2008 Oct 24 doi: 10.1038/modpathol.2008.174. PMID: 18953328
From the archives of the AFIP: Gastrointestinal carcinoids: imaging features with clinicopathologic comparison.
Levy AD, Sobin LH
Radiographics 2007 Jan-Feb;27(1):237-57. doi: 10.1148/rg.271065169. PMID: 17235010

Prognosis

Pathology of gastrointestinal disorders.
Rindi G, Inzani F, Solcia E
Endocrinol Metab Clin North Am 2010 Dec;39(4):713-27. doi: 10.1016/j.ecl.2010.08.009. PMID: 21095540
From the archives of the AFIP: Gastrointestinal carcinoids: imaging features with clinicopathologic comparison.
Levy AD, Sobin LH
Radiographics 2007 Jan-Feb;27(1):237-57. doi: 10.1148/rg.271065169. PMID: 17235010

Clinical prediction guides

Pathology of gastrointestinal disorders.
Rindi G, Inzani F, Solcia E
Endocrinol Metab Clin North Am 2010 Dec;39(4):713-27. doi: 10.1016/j.ecl.2010.08.009. PMID: 21095540

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