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Significant Arterial Dissection

MedGen UID:
476507
•Concept ID:
C3274874
•
Disease or Syndrome

Definition

A dissection that impairs flow. This includes Type C (a persisting contrast medium extravasation) in the presence of ischemia, Type D (a spiral filling defect with delayed but complete distal flow), Type E (persistent filling defect with delayed antegrade flow) and Type F (filling defect with impaired flow and total occlusion). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSignificant Arterial Dissection

Professional guidelines

PubMed

Radial Artery Access Complications: Prevention, Diagnosis and Management.
Roy S, Kabach M, Patel DB, Guzman LA, Jovin IS
Cardiovasc Revasc Med 2022 Jul;40:163-171. Epub 2021 Dec 16 doi: 10.1016/j.carrev.2021.12.007. PMID: 34952824
Optimal Treatment of Uncomplicated Type B Aortic Dissection: JACC Review Topic of the Week.
Tadros RO, Tang GHL, Barnes HJ, Mousavi I, Kovacic JC, Faries P, Olin JW, Marin ML, Adams DH
J Am Coll Cardiol 2019 Sep 17;74(11):1494-1504. doi: 10.1016/j.jacc.2019.07.063. PMID: 31514953
Type B Aortic Dissections: Current Guidelines for Treatment.
Alfson DB, Ham SW
Cardiol Clin 2017 Aug;35(3):387-410. Epub 2017 May 26 doi: 10.1016/j.ccl.2017.03.007. PMID: 28683909

Recent clinical studies

Etiology

Aortic Dissection: A Review of the Pathophysiology, Management and Prospective Advances.
Sayed A, Munir M, Bahbah EI
Curr Cardiol Rev 2021;17(4):e230421186875. doi: 10.2174/1573403X16666201014142930. PMID: 33059568Free PMC Article
Acute type A aortic dissection - a review.
Gudbjartsson T, Ahlsson A, Geirsson A, Gunn J, Hjortdal V, Jeppsson A, Mennander A, Zindovic I, Olsson C
Scand Cardiovasc J 2020 Feb;54(1):1-13. Epub 2019 Sep 23 doi: 10.1080/14017431.2019.1660401. PMID: 31542960
Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results.
Markus HS, Levi C, King A, Madigan J, Norris J; Cervical Artery Dissection in Stroke Study (CADISS) Investigators
JAMA Neurol 2019 Jun 1;76(6):657-664. doi: 10.1001/jamaneurol.2019.0072. PMID: 30801621Free PMC Article
Insights From the International Registry of Acute Aortic Dissection: A 20-Year Experience of Collaborative Clinical Research.
Evangelista A, Isselbacher EM, Bossone E, Gleason TG, Eusanio MD, Sechtem U, Ehrlich MP, Trimarchi S, Braverman AC, Myrmel T, Harris KM, Hutchinson S, O'Gara P, Suzuki T, Nienaber CA, Eagle KA; IRAD Investigators
Circulation 2018 Apr 24;137(17):1846-1860. doi: 10.1161/CIRCULATIONAHA.117.031264. PMID: 29685932
Type B Aortic Dissections: Current Guidelines for Treatment.
Alfson DB, Ham SW
Cardiol Clin 2017 Aug;35(3):387-410. Epub 2017 May 26 doi: 10.1016/j.ccl.2017.03.007. PMID: 28683909

Diagnosis

Loeys-Dietz Syndrome.
Velchev JD, Van Laer L, Luyckx I, Dietz H, Loeys B
Adv Exp Med Biol 2021;1348:251-264. doi: 10.1007/978-3-030-80614-9_11. PMID: 34807423
Aortic dissection during pregnancy and postpartum.
Meng X, Han J, Wang L, Wu Q
J Card Surg 2021 Jul;36(7):2510-2517. Epub 2021 Apr 29 doi: 10.1111/jocs.15575. PMID: 33928681
Aortic Dissection: A Review of the Pathophysiology, Management and Prospective Advances.
Sayed A, Munir M, Bahbah EI
Curr Cardiol Rev 2021;17(4):e230421186875. doi: 10.2174/1573403X16666201014142930. PMID: 33059568Free PMC Article
Acute type A aortic dissection - a review.
Gudbjartsson T, Ahlsson A, Geirsson A, Gunn J, Hjortdal V, Jeppsson A, Mennander A, Zindovic I, Olsson C
Scand Cardiovasc J 2020 Feb;54(1):1-13. Epub 2019 Sep 23 doi: 10.1080/14017431.2019.1660401. PMID: 31542960
Insights From the International Registry of Acute Aortic Dissection: A 20-Year Experience of Collaborative Clinical Research.
Evangelista A, Isselbacher EM, Bossone E, Gleason TG, Eusanio MD, Sechtem U, Ehrlich MP, Trimarchi S, Braverman AC, Myrmel T, Harris KM, Hutchinson S, O'Gara P, Suzuki T, Nienaber CA, Eagle KA; IRAD Investigators
Circulation 2018 Apr 24;137(17):1846-1860. doi: 10.1161/CIRCULATIONAHA.117.031264. PMID: 29685932

Therapy

Blood Pressure, Hypertension, and the Risk of Aortic Dissection Incidence and Mortality: Results From the J-SCH Study, the UK Biobank Study, and a Meta-Analysis of Cohort Studies.
Hibino M, Otaki Y, Kobeissi E, Pan H, Hibino H, Taddese H, Majeed A, Verma S, Konta T, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Iseki K, Moriyama T, Kondo M, Asahi K, Watanabe T, Watanabe T, Watanabe M, Aune D
Circulation 2022 Mar;145(9):633-644. Epub 2021 Nov 8 doi: 10.1161/CIRCULATIONAHA.121.056546. PMID: 34743557
Acute type A aortic dissection - a review.
Gudbjartsson T, Ahlsson A, Geirsson A, Gunn J, Hjortdal V, Jeppsson A, Mennander A, Zindovic I, Olsson C
Scand Cardiovasc J 2020 Feb;54(1):1-13. Epub 2019 Sep 23 doi: 10.1080/14017431.2019.1660401. PMID: 31542960
Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results.
Markus HS, Levi C, King A, Madigan J, Norris J; Cervical Artery Dissection in Stroke Study (CADISS) Investigators
JAMA Neurol 2019 Jun 1;76(6):657-664. doi: 10.1001/jamaneurol.2019.0072. PMID: 30801621Free PMC Article
Managing patients with acute type A aortic dissection and mesenteric malperfusion syndrome: A 20-year experience.
Yang B, Norton EL, Rosati CM, Wu X, Kim KM, Khaja MS, Deeb GM, Williams DM, Patel HJ
J Thorac Cardiovasc Surg 2019 Sep;158(3):675-687.e4. Epub 2018 Dec 14 doi: 10.1016/j.jtcvs.2018.11.127. PMID: 30711274Free PMC Article
Acute Aortic Dissection and Intramural Hematoma: A Systematic Review.
Mussa FF, Horton JD, Moridzadeh R, Nicholson J, Trimarchi S, Eagle KA
JAMA 2016 Aug 16;316(7):754-63. doi: 10.1001/jama.2016.10026. PMID: 27533160

Prognosis

Acute type A aortic dissection - a review.
Gudbjartsson T, Ahlsson A, Geirsson A, Gunn J, Hjortdal V, Jeppsson A, Mennander A, Zindovic I, Olsson C
Scand Cardiovasc J 2020 Feb;54(1):1-13. Epub 2019 Sep 23 doi: 10.1080/14017431.2019.1660401. PMID: 31542960
Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results.
Markus HS, Levi C, King A, Madigan J, Norris J; Cervical Artery Dissection in Stroke Study (CADISS) Investigators
JAMA Neurol 2019 Jun 1;76(6):657-664. doi: 10.1001/jamaneurol.2019.0072. PMID: 30801621Free PMC Article
Managing patients with acute type A aortic dissection and mesenteric malperfusion syndrome: A 20-year experience.
Yang B, Norton EL, Rosati CM, Wu X, Kim KM, Khaja MS, Deeb GM, Williams DM, Patel HJ
J Thorac Cardiovasc Surg 2019 Sep;158(3):675-687.e4. Epub 2018 Dec 14 doi: 10.1016/j.jtcvs.2018.11.127. PMID: 30711274Free PMC Article
Insights From the International Registry of Acute Aortic Dissection: A 20-Year Experience of Collaborative Clinical Research.
Evangelista A, Isselbacher EM, Bossone E, Gleason TG, Eusanio MD, Sechtem U, Ehrlich MP, Trimarchi S, Braverman AC, Myrmel T, Harris KM, Hutchinson S, O'Gara P, Suzuki T, Nienaber CA, Eagle KA; IRAD Investigators
Circulation 2018 Apr 24;137(17):1846-1860. doi: 10.1161/CIRCULATIONAHA.117.031264. PMID: 29685932
Presentation, Diagnosis, and Outcomes of Acute Aortic Dissection: 17-Year Trends From the International Registry of Acute Aortic Dissection.
Pape LA, Awais M, Woznicki EM, Suzuki T, Trimarchi S, Evangelista A, Myrmel T, Larsen M, Harris KM, Greason K, Di Eusanio M, Bossone E, Montgomery DG, Eagle KA, Nienaber CA, Isselbacher EM, O'Gara P
J Am Coll Cardiol 2015 Jul 28;66(4):350-8. doi: 10.1016/j.jacc.2015.05.029. PMID: 26205591

Clinical prediction guides

Low ambient temperature and temperature drop between neighbouring days and acute aortic dissection: a case-crossover study.
Chen J, Gao Y, Jiang Y, Li H, Lv M, Duan W, Lai H, Chen R, Wang C
Eur Heart J 2022 Jan 25;43(3):228-235. doi: 10.1093/eurheartj/ehab803. PMID: 34849712
OPG/TRAIL ratio as a predictive biomarker of mortality in patients with type A acute aortic dissection.
Lu J, Li P, Ma K, Li Y, Yuan H, Zhu J, Duan W, Ou J, Huang Y, Wu L, Pan X, Zhang H, Du J, Li Y
Nat Commun 2021 Jun 7;12(1):3401. doi: 10.1038/s41467-021-23787-5. PMID: 34099729Free PMC Article
Aortic dissection during pregnancy and postpartum.
Meng X, Han J, Wang L, Wu Q
J Card Surg 2021 Jul;36(7):2510-2517. Epub 2021 Apr 29 doi: 10.1111/jocs.15575. PMID: 33928681
Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results.
Markus HS, Levi C, King A, Madigan J, Norris J; Cervical Artery Dissection in Stroke Study (CADISS) Investigators
JAMA Neurol 2019 Jun 1;76(6):657-664. doi: 10.1001/jamaneurol.2019.0072. PMID: 30801621Free PMC Article
Insights From the International Registry of Acute Aortic Dissection: A 20-Year Experience of Collaborative Clinical Research.
Evangelista A, Isselbacher EM, Bossone E, Gleason TG, Eusanio MD, Sechtem U, Ehrlich MP, Trimarchi S, Braverman AC, Myrmel T, Harris KM, Hutchinson S, O'Gara P, Suzuki T, Nienaber CA, Eagle KA; IRAD Investigators
Circulation 2018 Apr 24;137(17):1846-1860. doi: 10.1161/CIRCULATIONAHA.117.031264. PMID: 29685932

Recent systematic reviews

Aortic dissection and Covid-19; a comprehensive systematic review.
Ramandi A, Akbarzadeh MA, Khaheshi I, Khalilian MR
Curr Probl Cardiol 2023 Jun;48(6):101129. Epub 2022 Feb 6 doi: 10.1016/j.cpcardiol.2022.101129. PMID: 35139402Free PMC Article
A Systematic Review and Meta-Analysis of Seasonal and Monthly Variability in the Incidence of Acute Aortic Dissection.
Wu H, Wang Z, Li M, Liu Q, Liu W, Qiao Z, Bai T, Liu Y, Zhang C, Sun P, Wei S, Bai H
Ann Vasc Surg 2022 Sep;85:383-394. Epub 2022 Apr 22 doi: 10.1016/j.avsg.2022.04.008. PMID: 35461996
Blood Pressure, Hypertension, and the Risk of Aortic Dissection Incidence and Mortality: Results From the J-SCH Study, the UK Biobank Study, and a Meta-Analysis of Cohort Studies.
Hibino M, Otaki Y, Kobeissi E, Pan H, Hibino H, Taddese H, Majeed A, Verma S, Konta T, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Iseki K, Moriyama T, Kondo M, Asahi K, Watanabe T, Watanabe T, Watanabe M, Aune D
Circulation 2022 Mar;145(9):633-644. Epub 2021 Nov 8 doi: 10.1161/CIRCULATIONAHA.121.056546. PMID: 34743557
Aortic dissection during pregnancy and postpartum.
Meng X, Han J, Wang L, Wu Q
J Card Surg 2021 Jul;36(7):2510-2517. Epub 2021 Apr 29 doi: 10.1111/jocs.15575. PMID: 33928681
Acute Aortic Dissection and Intramural Hematoma: A Systematic Review.
Mussa FF, Horton JD, Moridzadeh R, Nicholson J, Trimarchi S, Eagle KA
JAMA 2016 Aug 16;316(7):754-63. doi: 10.1001/jama.2016.10026. PMID: 27533160

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