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Cardiac Lead Insulation Failure

MedGen UID:
476698
•Concept ID:
C3275065
•
Finding

Definition

Insulation failure manifests as low lead impedance either absolutely (below manufacturer''s product specifications) or by a significant decrease from previously stable chronic values. (ACC) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCardiac Lead Insulation Failure

Professional guidelines

PubMed

Treatment of HeartMate II Short-to-Shield Patients With an Ungrounded Cable: Indications and Long-Term Outcomes.
Coyle L, Graney N, Gallagher C, Paliga R, Yost G, Pappas P, Macaluso G, Tatooles A
ASAIO J 2020 Apr;66(4):381-387. doi: 10.1097/MAT.0000000000001012. PMID: 31045924
Implantable Cardiac Defibrillator Lead Failure and Management.
Swerdlow CD, Kalahasty G, Ellenbogen KA
J Am Coll Cardiol 2016 Mar 22;67(11):1358-68. doi: 10.1016/j.jacc.2015.12.067. PMID: 26988958
Atrial "J" pacing lead retention wire fracture: radiographic assessment, incidence of fracture, and clinical management.
Lloyd MA, Hayes DL, Holmes DR Jr
Pacing Clin Electrophysiol 1995 May;18(5 Pt 1):958-64. doi: 10.1111/j.1540-8159.1995.tb04735.x. PMID: 7659568

Recent clinical studies

Etiology

A Review of the Recent Advances of Cardiac Pacemaker Technology in Handling Complications.
Lowe M, Nguyen L, Patel DJ
J Long Term Eff Med Implants 2023;33(4):21-29. doi: 10.1615/JLongTermEffMedImplants.2022039586. PMID: 37522582
Lead age as a predictor for failure in pediatrics and congenital heart disease.
Whitehill RD, Chandler SF, DeWitt E, Abrams DJ, Walsh EP, Kelleman M, Mah DY
Pacing Clin Electrophysiol 2021 Apr;44(4):586-594. Epub 2021 Feb 24 doi: 10.1111/pace.14166. PMID: 33432629
Incidence of Premature Lead Failure in 2088 Tendril(TM) Pacing Leads: A Single Centre Experience.
Segan L, Samuel R, Lim M, Ridley D, Sen J, Perrin M
Heart Lung Circ 2021 Jul;30(7):986-995. Epub 2020 Dec 4 doi: 10.1016/j.hlc.2020.11.002. PMID: 33288446
Lead-related complications after DDD pacemaker implantation.
Dębski M, Ulman M, Ząbek A, Boczar K, Haberka K, Kuniewicz M, Lelakowski J, Małecka B
Kardiol Pol 2018;76(8):1224-1231. Epub 2018 Apr 10 doi: 10.5603/KP.a2018.0089. PMID: 29633234
Fluoroscopic investigation of Riata® transvenous defibrillator leads.
Singh G, Lahiri MK, Khan A, Fang KD, Schuger CD
Cardiol J 2015;22(1):57-67. Epub 2014 May 20 doi: 10.5603/CJ.a2014.0039. PMID: 24846515

Diagnosis

Interpreting device diagnostics for lead failure.
Swerdlow CD, Ploux S, Poole JE, Nair SG, Himes A, Ellenbogen KA
Heart Rhythm 2022 Jan;19(1):154-164. Epub 2021 Sep 28 doi: 10.1016/j.hrthm.2021.09.027. PMID: 34597770
Impedance in the Diagnosis of Lead Malfunction.
Swerdlow CD, Koneru JN, Gunderson B, Kroll MW, Ploux S, Ellenbogen KA
Circ Arrhythm Electrophysiol 2020 Feb;13(2):e008092. Epub 2020 Jan 27 doi: 10.1161/CIRCEP.119.008092. PMID: 31985260
Monitoring for and Diagnosis of Lead Dysfunction.
Nair SG, Swerdlow CD
Card Electrophysiol Clin 2018 Dec;10(4):573-599. doi: 10.1016/j.ccep.2018.07.004. PMID: 30396573
Implantable Cardiac Defibrillator Lead Failure and Management.
Swerdlow CD, Kalahasty G, Ellenbogen KA
J Am Coll Cardiol 2016 Mar 22;67(11):1358-68. doi: 10.1016/j.jacc.2015.12.067. PMID: 26988958
Troubleshooting pacemakers and implantable cardioverter-defibrillators.
Scher DL
Curr Opin Cardiol 2004 Jan;19(1):36-46. doi: 10.1097/00001573-200401000-00009. PMID: 14688633

Therapy

Polarity-Dependent, Reduced or No-Output Shocks in Implantable Cardioverter-Defibrillators.
Swerdlow CD, Ringle M
JACC Clin Electrophysiol 2024 Mar;10(3):604-610. Epub 2024 Jan 24 doi: 10.1016/j.jacep.2023.11.023. PMID: 38276928
A Review of the Recent Advances of Cardiac Pacemaker Technology in Handling Complications.
Lowe M, Nguyen L, Patel DJ
J Long Term Eff Med Implants 2023;33(4):21-29. doi: 10.1615/JLongTermEffMedImplants.2022039586. PMID: 37522582
Lead age as a predictor for failure in pediatrics and congenital heart disease.
Whitehill RD, Chandler SF, DeWitt E, Abrams DJ, Walsh EP, Kelleman M, Mah DY
Pacing Clin Electrophysiol 2021 Apr;44(4):586-594. Epub 2021 Feb 24 doi: 10.1111/pace.14166. PMID: 33432629
Implantable Cardiac Defibrillator Lead Failure and Management.
Swerdlow CD, Kalahasty G, Ellenbogen KA
J Am Coll Cardiol 2016 Mar 22;67(11):1358-68. doi: 10.1016/j.jacc.2015.12.067. PMID: 26988958
Radiography of cardiac conduction devices: a comprehensive review.
Aguilera AL, Volokhina YV, Fisher KL
Radiographics 2011 Oct;31(6):1669-82. doi: 10.1148/rg.316115529. PMID: 21997988

Prognosis

A Review of the Recent Advances of Cardiac Pacemaker Technology in Handling Complications.
Lowe M, Nguyen L, Patel DJ
J Long Term Eff Med Implants 2023;33(4):21-29. doi: 10.1615/JLongTermEffMedImplants.2022039586. PMID: 37522582
Lead age as a predictor for failure in pediatrics and congenital heart disease.
Whitehill RD, Chandler SF, DeWitt E, Abrams DJ, Walsh EP, Kelleman M, Mah DY
Pacing Clin Electrophysiol 2021 Apr;44(4):586-594. Epub 2021 Feb 24 doi: 10.1111/pace.14166. PMID: 33432629
Incidence of Premature Lead Failure in 2088 Tendril(TM) Pacing Leads: A Single Centre Experience.
Segan L, Samuel R, Lim M, Ridley D, Sen J, Perrin M
Heart Lung Circ 2021 Jul;30(7):986-995. Epub 2020 Dec 4 doi: 10.1016/j.hlc.2020.11.002. PMID: 33288446
Lead-related complications after DDD pacemaker implantation.
Dębski M, Ulman M, Ząbek A, Boczar K, Haberka K, Kuniewicz M, Lelakowski J, Małecka B
Kardiol Pol 2018;76(8):1224-1231. Epub 2018 Apr 10 doi: 10.5603/KP.a2018.0089. PMID: 29633234
The implantable cardioverter-defibrillator lead: principles, progress, and promises.
Haqqani HM, Mond HG
Pacing Clin Electrophysiol 2009 Oct;32(10):1336-53. doi: 10.1111/j.1540-8159.2009.02492.x. PMID: 19796348

Clinical prediction guides

Polarity-Dependent, Reduced or No-Output Shocks in Implantable Cardioverter-Defibrillators.
Swerdlow CD, Ringle M
JACC Clin Electrophysiol 2024 Mar;10(3):604-610. Epub 2024 Jan 24 doi: 10.1016/j.jacep.2023.11.023. PMID: 38276928
A Review of the Recent Advances of Cardiac Pacemaker Technology in Handling Complications.
Lowe M, Nguyen L, Patel DJ
J Long Term Eff Med Implants 2023;33(4):21-29. doi: 10.1615/JLongTermEffMedImplants.2022039586. PMID: 37522582
Lead age as a predictor for failure in pediatrics and congenital heart disease.
Whitehill RD, Chandler SF, DeWitt E, Abrams DJ, Walsh EP, Kelleman M, Mah DY
Pacing Clin Electrophysiol 2021 Apr;44(4):586-594. Epub 2021 Feb 24 doi: 10.1111/pace.14166. PMID: 33432629
Implantable cardioverter-defibrillator lead revision following left ventricular assist device implantation.
Black-Maier E, Lewis RK, Rehorn M, Loungani R, Friedman DJ, Frazier-Mills C, Jackson KP, Atwater BD, Milano CA, Schroder JN, Pokorney SD, Piccini JP
J Cardiovasc Electrophysiol 2020 Jun;31(6):1509-1518. Epub 2020 Apr 29 doi: 10.1111/jce.14487. PMID: 32275340
Lead-related complications after DDD pacemaker implantation.
Dębski M, Ulman M, Ząbek A, Boczar K, Haberka K, Kuniewicz M, Lelakowski J, Małecka B
Kardiol Pol 2018;76(8):1224-1231. Epub 2018 Apr 10 doi: 10.5603/KP.a2018.0089. PMID: 29633234

Supplemental Content

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