U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Unilateral vertebral artery hypoplasia

MedGen UID:
480720
Concept ID:
C3279090
Finding
Synonym: Vertebral artery hypoplasia, unilateral
 
HPO: HP:0030323

Definition

Underdevelopment of the vertebral artery on one side. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnilateral vertebral artery hypoplasia

Conditions with this feature

Spondylocostal dysostosis 4, autosomal recessive
MedGen UID:
462292
Concept ID:
C3150942
Disease or Syndrome
Spondylocostal dysostosis (SCDO), defined radiographically as multiple segmentation defects of the vertebrae (M-SDV) in combination with abnormalities of the ribs, is characterized clinically by: a short trunk in proportion to height; short neck; non-progressive mild scoliosis in most affected individuals, and occasionally, more significant scoliosis. Respiratory function in neonates may be compromised by reduced size of the thorax. By age two years lung growth may improve sufficiently to support relatively normal growth and development; however, even then life-threatening complications can occur, especially pulmonary hypertension in children with severely restricted lung capacity from birth. Males with SCDO appear to be at increased risk for inguinal hernia.

Recent clinical studies

Etiology

Ozen O, Yuksel Y, Torun E, Ergun T
Surg Radiol Anat 2023 Apr;45(4):401-407. Epub 2023 Feb 22 doi: 10.1007/s00276-023-03108-9. PMID: 36813912
Beyhan M, Gökçe E, Karakuş K
Surg Radiol Anat 2020 Nov;42(11):1345-1354. Epub 2020 May 29 doi: 10.1007/s00276-020-02509-4. PMID: 32472183
Li JL, Li CS, Fu JH, Zhang K, Xu R, Xu WJ
Med Sci Monit 2015 Jun 15;21:1726-31. doi: 10.12659/msm.894388. PMID: 26073092Free PMC Article

Diagnosis

Beyhan M, Gökçe E, Karakuş K
Surg Radiol Anat 2020 Nov;42(11):1345-1354. Epub 2020 May 29 doi: 10.1007/s00276-020-02509-4. PMID: 32472183
Diaz FG, Ausman JI, Shrontz C, Pearce J, Gehring R, Mehta B, Dujovny M
Neurosurgery 1986 Jul;19(1):93-100. doi: 10.1227/00006123-198607000-00014. PMID: 3748345

Therapy

Beyhan M, Gökçe E, Karakuş K
Surg Radiol Anat 2020 Nov;42(11):1345-1354. Epub 2020 May 29 doi: 10.1007/s00276-020-02509-4. PMID: 32472183

Prognosis

Li JL, Li CS, Fu JH, Zhang K, Xu R, Xu WJ
Med Sci Monit 2015 Jun 15;21:1726-31. doi: 10.12659/msm.894388. PMID: 26073092Free PMC Article

Clinical prediction guides

Beyhan M, Gökçe E, Karakuş K
Surg Radiol Anat 2020 Nov;42(11):1345-1354. Epub 2020 May 29 doi: 10.1007/s00276-020-02509-4. PMID: 32472183
Li JL, Li CS, Fu JH, Zhang K, Xu R, Xu WJ
Med Sci Monit 2015 Jun 15;21:1726-31. doi: 10.12659/msm.894388. PMID: 26073092Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...