U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Renal artery obstruction

MedGen UID:
48406
•Concept ID:
C0035066
•
Disease or Syndrome
Synonyms: Obstruction, Renal Artery; Obstructions, Renal Artery; Renal Artery Obstruction; Renal Artery Obstructions
 
Monarch Initiative: MONDO:0006945

Definition

Narrowing or occlusion of the renal artery or arteries. It is due usually to atherosclerosis; fibromuscular dysplasia; thrombosis; embolism, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (hypertension, renovascular). [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRenal artery obstruction

Professional guidelines

PubMed

Assessment and management of peripheral arterial disease: what every cardiologist should know.
Tran B
Heart 2021 Nov;107(22):1835-1843. Epub 2021 May 13 doi: 10.1136/heartjnl-2019-316164. PMID: 33985986Free PMC Article
Clinical insights into the diagnosis and management of renovascular disease. An evidence-based review.
Bloch MJ, Basile J
Minerva Med 2004 Oct;95(5):357-73. PMID: 15467512
The diagnosis and management of renovascular disease: a primary care perspective. Part I. Making the diagnosis.
Bloch MJ, Basile J
J Clin Hypertens (Greenwich) 2003 May-Jun;5(3):210-8. doi: 10.1111/j.1524-6175.2003.01766.x. PMID: 12826784Free PMC Article

Recent clinical studies

Etiology

Renal artery stenosis.
Safian RD
Prog Cardiovasc Dis 2021 Mar-Apr;65:60-70. Epub 2021 Mar 18 doi: 10.1016/j.pcad.2021.03.003. PMID: 33745915
Renal revascularization in resistant hypertension.
Prince M, Gupta A, Bob-Manuel T, Tafur J
Prog Cardiovasc Dis 2020 Jan-Feb;63(1):58-63. Epub 2019 Dec 7 doi: 10.1016/j.pcad.2019.12.001. PMID: 31821813
Renovascular Hypertension: Novel Insights.
Boutari C, Georgianou E, Sachinidis A, Katsimardou A, Christou K, Piperidou A, Karagiannis A
Curr Hypertens Rev 2020;16(1):24-29. doi: 10.2174/1573402115666190416153321. PMID: 31038069
When and How Should We Revascularize Patients With Atherosclerotic Renal Artery Stenosis?
Prince M, Tafur JD, White CJ
JACC Cardiovasc Interv 2019 Mar 25;12(6):505-517. doi: 10.1016/j.jcin.2018.10.023. PMID: 30898248
Renal artery stenosis.
Tafur-Soto JD, White CJ
Cardiol Clin 2015 Feb;33(1):59-73. doi: 10.1016/j.ccl.2014.09.006. PMID: 25439331

Diagnosis

Transplant Renal Artery Stenosis: Current Concepts.
Gunawardena T, Sharma H
Exp Clin Transplant 2022 Dec;20(12):1049-1057. doi: 10.6002/ect.2022.0334. PMID: 36718003
Renovascular Disease and Mesenteric Vascular Disease.
Sharma S, Henkin S, Young MN
Cardiol Clin 2021 Nov;39(4):527-537. doi: 10.1016/j.ccl.2021.06.005. PMID: 34686265
Renal artery stenosis.
Safian RD
Prog Cardiovasc Dis 2021 Mar-Apr;65:60-70. Epub 2021 Mar 18 doi: 10.1016/j.pcad.2021.03.003. PMID: 33745915
Obstructive Kidney Disease.
Stevens S
Nurs Clin North Am 2018 Dec;53(4):569-578. Epub 2018 Oct 12 doi: 10.1016/j.cnur.2018.07.007. PMID: 30388982
Atherosclerotic renal artery stenosis--diagnosis and treatment.
Lao D, Parasher PS, Cho KC, Yeghiazarians Y
Mayo Clin Proc 2011 Jul;86(7):649-57. doi: 10.4065/mcp.2011.0181. PMID: 21719621Free PMC Article

Therapy

Renal artery stenosis.
Safian RD
Prog Cardiovasc Dis 2021 Mar-Apr;65:60-70. Epub 2021 Mar 18 doi: 10.1016/j.pcad.2021.03.003. PMID: 33745915
Renal revascularization in resistant hypertension.
Prince M, Gupta A, Bob-Manuel T, Tafur J
Prog Cardiovasc Dis 2020 Jan-Feb;63(1):58-63. Epub 2019 Dec 7 doi: 10.1016/j.pcad.2019.12.001. PMID: 31821813
Novel therapeutic strategies for renovascular disease.
Eirin A, Textor SC, Lerman LO
Curr Opin Nephrol Hypertens 2019 Jul;28(4):383-389. doi: 10.1097/MNH.0000000000000513. PMID: 31045658Free PMC Article
When and How Should We Revascularize Patients With Atherosclerotic Renal Artery Stenosis?
Prince M, Tafur JD, White CJ
JACC Cardiovasc Interv 2019 Mar 25;12(6):505-517. doi: 10.1016/j.jcin.2018.10.023. PMID: 30898248
Renal Artery Stenosis: Optimal Therapy and Indications for Revascularization.
Patel SM, Li J, Parikh SA
Curr Cardiol Rep 2015 Sep;17(9):623. doi: 10.1007/s11886-015-0623-7. PMID: 26238738

Prognosis

Management and Outcomes of Childhood Renal Artery Stenosis and Middle Aortic Syndrome.
Rumman RK, Matsuda-Abedini M, Langlois V, Radhakrishnan S, Lorenzo AJ, Amaral J, Mertens L, Parekh RS
Am J Hypertens 2018 May 7;31(6):687-695. doi: 10.1093/ajh/hpy014. PMID: 29373648
Current approaches to atherosclerotic obstructive renal artery stenosis.
Juncos LI, Textor S
Ther Adv Cardiovasc Dis 2015 Aug;9(4):153-7. Epub 2015 Apr 22 doi: 10.1177/1753944715579143. PMID: 25907506
Diagnosis and treatment of renal artery stenosis.
Plouin PF, Bax L
Nat Rev Nephrol 2010 Mar;6(3):151-9. Epub 2010 Jan 26 doi: 10.1038/nrneph.2009.230. PMID: 20101256
Renal artery stenosis and chronic ischemic nephropathy: epidemiology and diagnosis.
Kendrick J, Chonchol M
Adv Chronic Kidney Dis 2008 Oct;15(4):355-62. doi: 10.1053/j.ackd.2008.07.004. PMID: 18805381
Value, limitations, and techniques of renal artery stenting.
Bohannon WT, Silva MB Jr
Semin Vasc Surg 2003 Dec;16(4):300-10. doi: 10.1053/j.semvascsurg.2003.08.008. PMID: 14691772

Clinical prediction guides

Atherosclerotic Renal Artery Stenosis.
Schoepe R, McQuillan S, Valsan D, Teehan G
Adv Exp Med Biol 2017;956:209-213. doi: 10.1007/5584_2016_89. PMID: 27873231
Management of Renovascular Hypertension.
Smith A, Gaba RC, Bui JT, Minocha J
Tech Vasc Interv Radiol 2016 Sep;19(3):211-7. Epub 2016 Jun 3 doi: 10.1053/j.tvir.2016.06.006. PMID: 27641455
Mesenchymal stem cells and chronic renal artery stenosis.
Oliveira-Sales EB, Boim MA
Am J Physiol Renal Physiol 2016 Jan 1;310(1):F6-9. Epub 2015 Nov 4 doi: 10.1152/ajprenal.00341.2015. PMID: 26538439
Renal artery stenosis: Up-date on diagnosis and treatment.
Zeller T, Macharzina R, Rastan A, Beschorner U, Noory E
Vasa 2014 Jan;43(1):27-38. doi: 10.1024/0301-1526/a000325. PMID: 24429328
Atherosclerotic renal artery stenosis and renal artery stenting: an evolving therapeutic option.
Margey R, Hynes BG, Moran D, Kiernan TJ, Jaff MR
Expert Rev Cardiovasc Ther 2011 Oct;9(10):1347-60. doi: 10.1586/erc.11.143. PMID: 21985547

Recent systematic reviews

Endovascular Treatment of Transplant Renal Artery Stenosis: A Systematic Review and Meta-analysis.
Hinojosa-Gonzalez DE, Salgado-Garza G, Torres-Martinez M, Villegas-De Leon SU, Bueno-Gutierrez LC, Herrera-Carrillo FE, Gonzalez-Urquijo M, Segura Ibarra V, Fabiani MA, Flores-Villalba E
J Endovasc Ther 2022 Apr;29(2):294-306. Epub 2021 Aug 16 doi: 10.1177/15266028211038593. PMID: 34399594
Renal artery stent in solitary functioning kidneys: 77% of benefit: A systematic review with meta-analysis.
Ma Z, Liu L, Zhang B, Chen W, Yang J, Li H
Medicine (Baltimore) 2016 Sep;95(36):e4780. doi: 10.1097/MD.0000000000004780. PMID: 27603380Free PMC Article
Comparative Effectiveness of Management Strategies for Renal Artery Stenosis: An Updated Systematic Review.
Raman G, Adam GP, Halladay CW, Langberg VN, Azodo IA, Balk EM
Ann Intern Med 2016 Nov 1;165(9):635-649. Epub 2016 Aug 16 doi: 10.7326/M16-1053. PMID: 27536808
Efficacy of revascularization for renal artery stenosis caused by fibromuscular dysplasia: a systematic review and meta-analysis.
Trinquart L, Mounier-Vehier C, Sapoval M, Gagnon N, Plouin PF
Hypertension 2010 Sep;56(3):525-32. Epub 2010 Jul 12 doi: 10.1161/HYPERTENSIONAHA.110.152918. PMID: 20625080
Effectiveness of management strategies for renal artery stenosis: a systematic review.
Balk E, Raman G, Chung M, Ip S, Tatsioni A, Alonso A, Chew P, Gilbert SJ, Lau J
Ann Intern Med 2006 Dec 19;145(12):901-12. Epub 2006 Oct 24 doi: 10.7326/0003-4819-145-12-200612190-00143. PMID: 17062633

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...