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Scabies

MedGen UID:
48566
•Concept ID:
C0036262
•
Disease or Syndrome
Synonyms: infestation by Sarcoptes scabiei; Infestation by Sarcoptes scabiei var hominis; infestation by Sarcoptes scabiei var hominis; Infestation caused by Sarcoptes scabiei var hominis; Sarcoptes scabiei caused disease or disorder; Sarcoptes scabiei disease or disorder; Sarcoptes scabiei infectious disease; Sarcoptic itch; sarcoptic itch; scabies
SNOMED CT: Scabies (128869009); Sarcoptic itch (128869009); Infestation by Sarcoptes scabiei var hominis (128869009); Infestation caused by Sarcoptes scabiei var hominis (128869009)
 
Monarch Initiative: MONDO:0004525

Definition

A contagious skin infection that is caused by the burrowing parasitic mite, Sarcoptes scabiei, and is characterized by intense itching and small, raised red spots in the area of the mite burrows. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVScabies

Professional guidelines

PubMed

Scabies: Epidemiology, Diagnosis, and Treatment.
Sunderkötter C, Wohlrab J, Hamm H
Dtsch Arztebl Int 2021 Oct 15;118(41):695-704. doi: 10.3238/arztebl.m2021.0296. PMID: 34615594Free PMC Article
Management of scabies.
Vasanwala FF, Ong CY, Aw CWD, How CH
Singapore Med J 2019 Jun;60(6):281-285. doi: 10.11622/smedj.2019058. PMID: 31243462Free PMC Article
European guideline for the management of scabies.
Salavastru CM, Chosidow O, Boffa MJ, Janier M, Tiplica GS
J Eur Acad Dermatol Venereol 2017 Aug;31(8):1248-1253. Epub 2017 Jun 22 doi: 10.1111/jdv.14351. PMID: 28639722

Recent clinical studies

Etiology

Scabies: Epidemiology, Diagnosis, and Treatment.
Sunderkötter C, Wohlrab J, Hamm H
Dtsch Arztebl Int 2021 Oct 15;118(41):695-704. doi: 10.3238/arztebl.m2021.0296. PMID: 34615594Free PMC Article
The Management of Scabies in the 21st Century: Past, Advances and Potentials.
Bernigaud C, Fischer K, Chosidow O
Acta Derm Venereol 2020 Apr 20;100(9):adv00112. doi: 10.2340/00015555-3468. PMID: 32207535Free PMC Article
The 2020 International Alliance for the Control of Scabies Consensus Criteria for the Diagnosis of Scabies.
Engelman D, Yoshizumi J, Hay RJ, Osti M, Micali G, Norton S, Walton S, Boralevi F, Bernigaud C, Bowen AC, Chang AY, Chosidow O, Estrada-Chavez G, Feldmeier H, Ishii N, Lacarrubba F, Mahé A, Maurer T, Mahdi MMA, Murdoch ME, Pariser D, Nair PA, Rehmus W, Romani L, Tilakaratne D, Tuicakau M, Walker SL, Wanat KA, Whitfeld MJ, Yotsu RR, Steer AC, Fuller LC
Br J Dermatol 2020 Nov;183(5):808-820. Epub 2020 Mar 29 doi: 10.1111/bjd.18943. PMID: 32034956Free PMC Article
Scabies: A Neglected Global Disease.
Leung AKC, Lam JM, Leong KF
Curr Pediatr Rev 2020;16(1):33-42. doi: 10.2174/1573396315666190717114131. PMID: 31544694
Ivermectin and permethrin for treating scabies.
Rosumeck S, Nast A, Dressler C
Cochrane Database Syst Rev 2018 Apr 2;4(4):CD012994. doi: 10.1002/14651858.CD012994. PMID: 29608022Free PMC Article

Diagnosis

Scabies: Epidemiology, Diagnosis, and Treatment.
Sunderkötter C, Wohlrab J, Hamm H
Dtsch Arztebl Int 2021 Oct 15;118(41):695-704. doi: 10.3238/arztebl.m2021.0296. PMID: 34615594Free PMC Article
Scabies: Diagnostic and Therapeutic Update.
Richards RN
J Cutan Med Surg 2021 Jan-Feb;25(1):95-101. Epub 2020 Sep 30 doi: 10.1177/1203475420960446. PMID: 32998532
Scabies: A Neglected Global Disease.
Leung AKC, Lam JM, Leong KF
Curr Pediatr Rev 2020;16(1):33-42. doi: 10.2174/1573396315666190717114131. PMID: 31544694
Ectoparasites: Scabies.
Thomas C, Coates SJ, Engelman D, Chosidow O, Chang AY
J Am Acad Dermatol 2020 Mar;82(3):533-548. Epub 2019 Jul 13 doi: 10.1016/j.jaad.2019.05.109. PMID: 31310840
Management of scabies.
Vasanwala FF, Ong CY, Aw CWD, How CH
Singapore Med J 2019 Jun;60(6):281-285. doi: 10.11622/smedj.2019058. PMID: 31243462Free PMC Article

Therapy

Scabies: Epidemiology, Diagnosis, and Treatment.
Sunderkötter C, Wohlrab J, Hamm H
Dtsch Arztebl Int 2021 Oct 15;118(41):695-704. doi: 10.3238/arztebl.m2021.0296. PMID: 34615594Free PMC Article
Scabies: Diagnostic and Therapeutic Update.
Richards RN
J Cutan Med Surg 2021 Jan-Feb;25(1):95-101. Epub 2020 Sep 30 doi: 10.1177/1203475420960446. PMID: 32998532
Scabies: A Neglected Global Disease.
Leung AKC, Lam JM, Leong KF
Curr Pediatr Rev 2020;16(1):33-42. doi: 10.2174/1573396315666190717114131. PMID: 31544694
Ectoparasites: Scabies.
Thomas C, Coates SJ, Engelman D, Chosidow O, Chang AY
J Am Acad Dermatol 2020 Mar;82(3):533-548. Epub 2019 Jul 13 doi: 10.1016/j.jaad.2019.05.109. PMID: 31310840
Management of scabies.
Vasanwala FF, Ong CY, Aw CWD, How CH
Singapore Med J 2019 Jun;60(6):281-285. doi: 10.11622/smedj.2019058. PMID: 31243462Free PMC Article

Prognosis

Scabies: A Neglected Global Disease.
Leung AKC, Lam JM, Leong KF
Curr Pediatr Rev 2020;16(1):33-42. doi: 10.2174/1573396315666190717114131. PMID: 31544694
Delusional infestation in psychodermatology.
Rosales Santillan M, Taylor DL, Reichenberg JS
G Ital Dermatol Venereol 2018 Aug;153(4):497-505. Epub 2018 Apr 18 doi: 10.23736/S0392-0488.18.05984-9. PMID: 29667798
Scabies.
Rosamilia LL
Semin Cutan Med Surg 2014 Sep;33(3):106-9. doi: 10.12788/j.sder.0103. PMID: 25577847
The global burden of skin disease in 2010: an analysis of the prevalence and impact of skin conditions.
Hay RJ, Johns NE, Williams HC, Bolliger IW, Dellavalle RP, Margolis DJ, Marks R, Naldi L, Weinstock MA, Wulf SK, Michaud C, J L Murray C, Naghavi M
J Invest Dermatol 2014 Jun;134(6):1527-1534. Epub 2013 Oct 28 doi: 10.1038/jid.2013.446. PMID: 24166134
Scabies.
Heukelbach J, Feldmeier H
Lancet 2006 May 27;367(9524):1767-74. doi: 10.1016/S0140-6736(06)68772-2. PMID: 16731272

Clinical prediction guides

Scabies: A Neglected Global Disease.
Leung AKC, Lam JM, Leong KF
Curr Pediatr Rev 2020;16(1):33-42. doi: 10.2174/1573396315666190717114131. PMID: 31544694
Increase of scabies in Germany and development of resistant mites? Evidence and consequences.
Sunderkötter C, Aebischer A, Neufeld M, Löser C, Kreuter A, Bialek R, Hamm H, Feldmeier H
J Dtsch Dermatol Ges 2019 Jan;17(1):15-23. Epub 2018 Nov 27 doi: 10.1111/ddg.13706. PMID: 30480868
Delusional infestation in psychodermatology.
Rosales Santillan M, Taylor DL, Reichenberg JS
G Ital Dermatol Venereol 2018 Aug;153(4):497-505. Epub 2018 Apr 18 doi: 10.23736/S0392-0488.18.05984-9. PMID: 29667798
European guideline for the management of scabies.
Salavastru CM, Chosidow O, Boffa MJ, Janier M, Tiplica GS
J Eur Acad Dermatol Venereol 2017 Aug;31(8):1248-1253. Epub 2017 Jun 22 doi: 10.1111/jdv.14351. PMID: 28639722
Scabies.
Johnstone PP, Strong M
BMJ Clin Evid 2008 Aug 22;2008 PMID: 19445807Free PMC Article

Recent systematic reviews

Ivermectin, a potential anticancer drug derived from an antiparasitic drug.
Tang M, Hu X, Wang Y, Yao X, Zhang W, Yu C, Cheng F, Li J, Fang Q
Pharmacol Res 2021 Jan;163:105207. Epub 2020 Sep 21 doi: 10.1016/j.phrs.2020.105207. PMID: 32971268Free PMC Article
Treatment, prevention and public health management of impetigo, scabies, crusted scabies and fungal skin infections in endemic populations: a systematic review.
May PJ, Tong SYC, Steer AC, Currie BJ, Andrews RM, Carapetis JR, Bowen AC
Trop Med Int Health 2019 Mar;24(3):280-293. Epub 2019 Jan 28 doi: 10.1111/tmi.13198. PMID: 30582783Free PMC Article
Ivermectin and permethrin for treating scabies.
Rosumeck S, Nast A, Dressler C
Cochrane Database Syst Rev 2018 Apr 2;4(4):CD012994. doi: 10.1002/14651858.CD012994. PMID: 29608022Free PMC Article
Prevalence of scabies and impetigo worldwide: a systematic review.
Romani L, Steer AC, Whitfeld MJ, Kaldor JM
Lancet Infect Dis 2015 Aug;15(8):960-7. Epub 2015 Jun 15 doi: 10.1016/S1473-3099(15)00132-2. PMID: 26088526
Scabies.
Johnstone PP, Strong M
BMJ Clin Evid 2008 Aug 22;2008 PMID: 19445807Free PMC Article

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