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Thyrotoxicosis with toxic multinodular goiter

MedGen UID:
488787
Concept ID:
C0154143
Disease or Syndrome
Synonyms: Secondary thyroid hyperplasia; Thyrotoxicosis due to multinodular goiter; Thyrotoxicosis with toxic multinodular goitre; Toxic multinodular goiter; Toxic multinodular thyroid goiter
SNOMED CT: Toxic multinodular thyroid goiter (26389007); Toxic multinodular goiter (26389007); Secondary thyroid hyperplasia (26389007); Thyrotoxicosis due to multinodular goiter (26389007); Thyrotoxicosis with toxic multinodular goiter (26389007)
 
HPO: HP:0011785

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThyrotoxicosis with toxic multinodular goiter

Professional guidelines

PubMed

Wong R, Farrell SG, Grossmann M
Med J Aust 2018 Jul 16;209(2):92-98. doi: 10.5694/mja17.01204. PMID: 29996756
Ross DS, Burch HB, Cooper DS, Greenlee MC, Laurberg P, Maia AL, Rivkees SA, Samuels M, Sosa JA, Stan MN, Walter MA
Thyroid 2016 Oct;26(10):1343-1421. doi: 10.1089/thy.2016.0229. PMID: 27521067
Bahn Chair RS, Burch HB, Cooper DS, Garber JR, Greenlee MC, Klein I, Laurberg P, McDougall IR, Montori VM, Rivkees SA, Ross DS, Sosa JA, Stan MN; American Thyroid Association; American Association of Clinical Endocrinologists
Thyroid 2011 Jun;21(6):593-646. Epub 2011 Apr 21 doi: 10.1089/thy.2010.0417. PMID: 21510801

Curated

UK NICE Guideline NG145, Thyroid disease: assessment and management, 2023

Recent clinical studies

Etiology

McDermott MT
Ann Intern Med 2020 Apr 7;172(7):ITC49-ITC64. doi: 10.7326/AITC202004070. PMID: 32252086
Wong R, Farrell SG, Grossmann M
Med J Aust 2018 Jul 16;209(2):92-98. doi: 10.5694/mja17.01204. PMID: 29996756
Ross DS, Burch HB, Cooper DS, Greenlee MC, Laurberg P, Maia AL, Rivkees SA, Samuels M, Sosa JA, Stan MN, Walter MA
Thyroid 2016 Oct;26(10):1343-1421. doi: 10.1089/thy.2016.0229. PMID: 27521067
Bahn Chair RS, Burch HB, Cooper DS, Garber JR, Greenlee MC, Klein I, Laurberg P, McDougall IR, Montori VM, Rivkees SA, Ross DS, Sosa JA, Stan MN; American Thyroid Association; American Association of Clinical Endocrinologists
Thyroid 2011 Jun;21(6):593-646. Epub 2011 Apr 21 doi: 10.1089/thy.2010.0417. PMID: 21510801
Maji D
J Indian Med Assoc 2006 Oct;104(10):563-4, 566-7. PMID: 17380820

Diagnosis

McDermott MT
Ann Intern Med 2020 Apr 7;172(7):ITC49-ITC64. doi: 10.7326/AITC202004070. PMID: 32252086
Wong R, Farrell SG, Grossmann M
Med J Aust 2018 Jul 16;209(2):92-98. doi: 10.5694/mja17.01204. PMID: 29996756
Ross DS, Burch HB, Cooper DS, Greenlee MC, Laurberg P, Maia AL, Rivkees SA, Samuels M, Sosa JA, Stan MN, Walter MA
Thyroid 2016 Oct;26(10):1343-1421. doi: 10.1089/thy.2016.0229. PMID: 27521067
Cooper DS, Laurberg P
Lancet Diabetes Endocrinol 2013 Nov;1(3):238-49. Epub 2013 Oct 18 doi: 10.1016/S2213-8587(13)70086-X. PMID: 24622372
Bahn Chair RS, Burch HB, Cooper DS, Garber JR, Greenlee MC, Klein I, Laurberg P, McDougall IR, Montori VM, Rivkees SA, Ross DS, Sosa JA, Stan MN; American Thyroid Association; American Association of Clinical Endocrinologists
Thyroid 2011 Jun;21(6):593-646. Epub 2011 Apr 21 doi: 10.1089/thy.2010.0417. PMID: 21510801

Therapy

McDermott MT
Ann Intern Med 2020 Apr 7;172(7):ITC49-ITC64. doi: 10.7326/AITC202004070. PMID: 32252086
Ross DS, Burch HB, Cooper DS, Greenlee MC, Laurberg P, Maia AL, Rivkees SA, Samuels M, Sosa JA, Stan MN, Walter MA
Thyroid 2016 Oct;26(10):1343-1421. doi: 10.1089/thy.2016.0229. PMID: 27521067
Cooper DS, Laurberg P
Lancet Diabetes Endocrinol 2013 Nov;1(3):238-49. Epub 2013 Oct 18 doi: 10.1016/S2213-8587(13)70086-X. PMID: 24622372
Bahn Chair RS, Burch HB, Cooper DS, Garber JR, Greenlee MC, Klein I, Laurberg P, McDougall IR, Montori VM, Rivkees SA, Ross DS, Sosa JA, Stan MN; American Thyroid Association; American Association of Clinical Endocrinologists
Thyroid 2011 Jun;21(6):593-646. Epub 2011 Apr 21 doi: 10.1089/thy.2010.0417. PMID: 21510801
Sharma M, Aronow WS, Patel L, Gandhi K, Desai H
Med Sci Monit 2011 Apr;17(4):RA85-91. doi: 10.12659/msm.881705. PMID: 21455118Free PMC Article

Prognosis

Abera BT, Abera MA, Berhe G, Abreha GF, Gebru HT, Abraha HE, Ebrahim MM
BMC Endocr Disord 2021 Jun 28;21(1):132. doi: 10.1186/s12902-021-00796-5. PMID: 34182968Free PMC Article
Leung AKC, Leung AAC
Recent Pat Endocr Metab Immune Drug Discov 2017;11(1):22-31. doi: 10.2174/1872214812666180327112540. PMID: 29589552
Pazaitou-Panayiotou K, Michalakis K, Paschke R
Horm Metab Res 2012 Apr;44(4):255-62. Epub 2012 Feb 14 doi: 10.1055/s-0031-1299741. PMID: 22334393
Vitti P, Rago T, Tonacchera M, Pinchera A
J Endocrinol Invest 2002;25(10 Suppl):16-8. PMID: 12508907
Hurley DL, Gharib H
Otolaryngol Clin North Am 1996 Aug;29(4):527-40. PMID: 8844728

Clinical prediction guides

Abera BT, Abera MA, Berhe G, Abreha GF, Gebru HT, Abraha HE, Ebrahim MM
BMC Endocr Disord 2021 Jun 28;21(1):132. doi: 10.1186/s12902-021-00796-5. PMID: 34182968Free PMC Article
Leung AKC, Leung AAC
Recent Pat Endocr Metab Immune Drug Discov 2017;11(1):22-31. doi: 10.2174/1872214812666180327112540. PMID: 29589552
Carlé A, Andersen SL, Boelaert K, Laurberg P
Eur J Endocrinol 2017 Jun;176(6):R325-R337. Epub 2017 Mar 8 doi: 10.1530/EJE-16-0276. PMID: 28274949
Vitti P, Rago T, Tonacchera M, Pinchera A
J Endocrinol Invest 2002;25(10 Suppl):16-8. PMID: 12508907
Hurley DL, Gharib H
Otolaryngol Clin North Am 1996 Aug;29(4):527-40. PMID: 8844728

Recent systematic reviews

Varadharajan K, Choudhury N
Clin Otolaryngol 2020 Jul;45(4):538-544. Epub 2020 Apr 20 doi: 10.1111/coa.13527. PMID: 32149464
Porterfield JR Jr, Thompson GB, Farley DR, Grant CS, Richards ML
World J Surg 2008 Jul;32(7):1278-84. doi: 10.1007/s00268-008-9566-0. PMID: 18357484

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2023
      UK NICE Guideline NG145, Thyroid disease: assessment and management, 2023

    Consumer resources

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