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Nasal regurgitation

MedGen UID:
488797
•Concept ID:
C0232608
•
Sign or Symptom
SNOMED CT: Nasal regurgitation (85023004)
 
HPO: HP:0011469

Definition

Regurgitation of milk through the nose. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNasal regurgitation

Conditions with this feature

Facial palsy, congenital, with ptosis and velopharyngeal dysfunction
MedGen UID:
1623077
•Concept ID:
C4540277
•
Disease or Syndrome
See: Condition Record
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 5
MedGen UID:
1648331
•Concept ID:
C4748184
•
Disease or Syndrome
See: Condition Record
Facial palsy, congenital, with ptosis and velopharyngeal dysfunction
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 5

Professional guidelines

PubMed

Adenoidectomy and persistent velopharyngeal insufficiency: Considerations, risk factors, and treatment.
Lambert EM, You P, Kacmarynski DS, Rosenberg TL
Int J Pediatr Otorhinolaryngol 2021 Oct;149:110846. Epub 2021 Jul 17 doi: 10.1016/j.ijporl.2021.110846. PMID: 34329831
Incidence and Treatment Protocol for Maxillofacial Fungal Osteomyelitis: A 12-Year Study.
Anehosur V, Agrawal SM, Joshi VK, Anand J, Krishnamuthy K, Kumar N
J Oral Maxillofac Surg 2019 Nov;77(11):2285-2291. Epub 2019 Jul 5 doi: 10.1016/j.joms.2019.06.187. PMID: 31445035
A review of the evaluation and management of velopharyngeal insufficiency in children.
Ruda JM, Krakovitz P, Rose AS
Otolaryngol Clin North Am 2012 Jun;45(3):653-69, viii. doi: 10.1016/j.otc.2012.03.005. PMID: 22588042

Recent clinical studies

Etiology

Adenoidectomy and persistent velopharyngeal insufficiency: Considerations, risk factors, and treatment.
Lambert EM, You P, Kacmarynski DS, Rosenberg TL
Int J Pediatr Otorhinolaryngol 2021 Oct;149:110846. Epub 2021 Jul 17 doi: 10.1016/j.ijporl.2021.110846. PMID: 34329831
Surgical management in submucous cleft palate patients.
Smarius BJA, Guillaume CHAL, Slegers J, Mink van der Molen AB, Breugem CC
Clin Oral Investig 2021 Jun;25(6):3893-3903. Epub 2021 Feb 1 doi: 10.1007/s00784-020-03719-1. PMID: 33521885Free PMC Article
Oro-Nasal Communication.
Sahoo NK, Desai AP, Roy ID, Kulkarni V
J Craniofac Surg 2016 Sep;27(6):e529-33. doi: 10.1097/SCS.0000000000002815. PMID: 27607130
Neurogenic [corrected] and oropharyngeal dysphagia.
Rofes L, Clavé P, Ouyang A, Scharitzer M, Pokieser P, Vilardell N, Ortega O
Ann N Y Acad Sci 2013 Oct;1300:1-10. doi: 10.1111/nyas.12234. PMID: 24117630
Review article: the gastrointestinal complications of myositis.
Ebert EC
Aliment Pharmacol Ther 2010 Feb 1;31(3):359-65. Epub 2009 Nov 3 doi: 10.1111/j.1365-2036.2009.04190.x. PMID: 19886949

Diagnosis

Adenoidectomy and persistent velopharyngeal insufficiency: Considerations, risk factors, and treatment.
Lambert EM, You P, Kacmarynski DS, Rosenberg TL
Int J Pediatr Otorhinolaryngol 2021 Oct;149:110846. Epub 2021 Jul 17 doi: 10.1016/j.ijporl.2021.110846. PMID: 34329831
Velopharyngeal incompetence: role in paediatric swallowing deficits.
Swibel Rosenthal LH, Walsh K, Thompson DM
Curr Opin Otolaryngol Head Neck Surg 2018 Dec;26(6):356-366. doi: 10.1097/MOO.0000000000000494. PMID: 30300209
A review of the evaluation and management of velopharyngeal insufficiency in children.
Ruda JM, Krakovitz P, Rose AS
Otolaryngol Clin North Am 2012 Jun;45(3):653-69, viii. doi: 10.1016/j.otc.2012.03.005. PMID: 22588042
Hemipalatal hypoplasia.
Tan YC, Chen PK
J Craniofac Surg 2009 Jul;20(4):1150-3. doi: 10.1097/SCS.0b013e3181abb3ce. PMID: 19506523
Nasopharyngeal carcinoma.
Brennan B
Orphanet J Rare Dis 2006 Jun 26;1:23. doi: 10.1186/1750-1172-1-23. PMID: 16800883Free PMC Article

Therapy

69-Year Old Man With Dysphagia and Nasal Regurgitation.
Tome J, Kamboj AK, Loftus CG
Mayo Clin Proc 2021 Nov;96(11):2917-2922. doi: 10.1016/j.mayocp.2021.03.040. PMID: 34736615
Velopharyngeal dysfunction from intranasal substance abuse: Case series and review of literature.
You P, Chow L, Dworschak-Stokan A, Husein M
Laryngoscope 2018 Dec;128(12):2721-2725. Epub 2018 May 14 doi: 10.1002/lary.27240. PMID: 29756302
Closure of fistula of the hard palate with two layers of mucoperiosteum.
Abdel-Aziz M, Kamel A, Fawaz M, Rezk I, Kamel M
Int J Pediatr Otorhinolaryngol 2018 Jan;104:43-46. Epub 2017 Oct 31 doi: 10.1016/j.ijporl.2017.10.037. PMID: 29287878
Radiofrequency uvulopalatoplasty for primary snoring.
Samimi Ardestani SH, Dadgarnia MH, Baradaranfar MH, Mazidi M, Rabbani M, Behniafard N, Baradaranfar A
Acta Med Iran 2013 Sep 9;51(8):530-6. PMID: 24026989
Nasopharyngeal carcinoma.
Brennan B
Orphanet J Rare Dis 2006 Jun 26;1:23. doi: 10.1186/1750-1172-1-23. PMID: 16800883Free PMC Article

Prognosis

Soft palate reconstruction with free jejunum flap: Impact on the velopharyngeal insufficiency.
Amendola F, Spadoni D, Losco L, Velazquez-Mujica J, Chen SH, Chen HC
J Plast Reconstr Aesthet Surg 2022 Aug;75(8):2684-2690. Epub 2022 Apr 28 doi: 10.1016/j.bjps.2022.04.044. PMID: 35577739
Risk Factors for Fistula Development Following Palatoplasty.
Aldaghir OM, AlQuisi AF, Aljumaily HA
J Craniofac Surg 2019 Nov-Dec;30(8):e694-e696. doi: 10.1097/SCS.0000000000005635. PMID: 31188249
Speech and Speech-Related Quality of Life After Late Palate Repair: A Patient's Perspective.
Schönmeyr B, Wendby L, Sharma M, Jacobson L, Restrepo C, Campbell A
J Craniofac Surg 2015 Jul;26(5):1513-6. doi: 10.1097/SCS.0000000000001811. PMID: 26114520
Review article: the gastrointestinal complications of myositis.
Ebert EC
Aliment Pharmacol Ther 2010 Feb 1;31(3):359-65. Epub 2009 Nov 3 doi: 10.1111/j.1365-2036.2009.04190.x. PMID: 19886949
Nasopharyngeal carcinoma.
Brennan B
Orphanet J Rare Dis 2006 Jun 26;1:23. doi: 10.1186/1750-1172-1-23. PMID: 16800883Free PMC Article

Clinical prediction guides

Patient and parent reported outcome measures in cleft lip and palate patients before and after secondary alveolar bone grafting.
Chang CS, Wallace CG, Hsiao YC, Lu TC, Chen SH, Chan FC, Chen PK, Chen JP, Chang CJ, Noordhoff MS
Medicine (Baltimore) 2017 Dec;96(52):e9541. doi: 10.1097/MD.0000000000009541. PMID: 29384973Free PMC Article
Swallowing characteristics in Amyotrophic Lateral Sclerosis.
Jani MP, Gore GB
NeuroRehabilitation 2016 Jun 27;39(2):273-6. doi: 10.3233/NRE-161357. PMID: 27372362
Oropharyngeal Dysphagia in Dermatomyositis: Associations with Clinical and Laboratory Features Including Autoantibodies.
Mugii N, Hasegawa M, Matsushita T, Hamaguchi Y, Oohata S, Okita H, Yahata T, Someya F, Inoue K, Murono S, Fujimoto M, Takehara K
PLoS One 2016;11(5):e0154746. Epub 2016 May 11 doi: 10.1371/journal.pone.0154746. PMID: 27167831Free PMC Article
Radiofrequency uvulopalatoplasty for primary snoring.
Samimi Ardestani SH, Dadgarnia MH, Baradaranfar MH, Mazidi M, Rabbani M, Behniafard N, Baradaranfar A
Acta Med Iran 2013 Sep 9;51(8):530-6. PMID: 24026989
Noma: a neglected scourge of children in sub-Saharan Africa.
Enwonwu CO
Bull World Health Organ 1995;73(4):541-5. PMID: 7554028Free PMC Article

Recent systematic reviews

Surgery for obstructive sleep apnoea.
Sundaram S, Bridgman SA, Lim J, Lasserson TJ
Cochrane Database Syst Rev 2005 Oct 19;(4):CD001004. doi: 10.1002/14651858.CD001004.pub2. PMID: 16235277

Supplemental Content

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