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Cardiac teratoma

MedGen UID:
488953
Concept ID:
C1112387
Neoplastic Process
Synonyms: Cardiac Teratoma; Heart Teratoma
 
HPO: HP:0011674

Definition

A teratoma within the heart. Most commonly, these tumors are detected in the pericardial cavity attached to the pulmonary artery and aorta. The tumor size within the heart varies from 2 to 9 cm in diameter, and intrapericardial tumors as large as 15 cm have been reported. Intracardiac tumors arise from the atrial or ventricular wall as nodular masses protruding into the cardiac chambers. Cardiac and pericardial teratomas are easily detected in the fetus and neonate by two-dimensional echocardiography as heterogeneous and encapsulated cystic masses. Histologically, cardiac teratomas contain multiple immature elements including epithelium, neuroglial tissue, thyroid, pancreas, smooth and skeletal muscle, cartilage and bone. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCardiac teratoma

Professional guidelines

PubMed

Nassr AA, Shazly SA, Morris SA, Ayres N, Espinoza J, Erfani H, Olutoye OA, Sexson SK, Olutoye OO, Fraser CD Jr, Belfort MA, Shamshirsaz AA
Prenat Diagn 2017 Sep;37(9):849-863. Epub 2017 Aug 7 doi: 10.1002/pd.5113. PMID: 28695637
Kornacki J, Skrzypczak J
Ginekol Pol 2017;88(5):266-269. doi: 10.5603/GP.a2017.0050. PMID: 28580573
Cass DL
Semin Fetal Neonatal Med 2011 Jun;16(3):130-8. Epub 2011 May 6 doi: 10.1016/j.siny.2011.03.007. PMID: 21530431

Recent clinical studies

Etiology

Cohen R, Mirrer B, Loarte P, Navarro V
Clin Cardiol 2013 Jan;36(1):6-9. Epub 2012 Sep 24 doi: 10.1002/clc.22051. PMID: 23007804Free PMC Article
Martinez-Climent J, Cavalle T, Ferris Tortajada J
Eur J Pediatr Surg 1995 Jun;5(3):156-9. doi: 10.1055/s-2008-1066193. PMID: 7547802

Diagnosis

Mendes GS, Abecasis J, Gouveia R, Castro M, Carvalho S, Ramos S, Abecasis M
Cardiovasc Pathol 2019 Mar-Apr;39:1-4. Epub 2018 Oct 29 doi: 10.1016/j.carpath.2018.10.007. PMID: 30503973
Cohen R, Mirrer B, Loarte P, Navarro V
Clin Cardiol 2013 Jan;36(1):6-9. Epub 2012 Sep 24 doi: 10.1002/clc.22051. PMID: 23007804Free PMC Article
Nemec SF, Horcher E, Kasprian G, Brugger PC, Bettelheim D, Amann G, Nemec U, Rotmensch S, Rimoin DL, Graham JM Jr, Prayer D
Eur J Radiol 2012 Feb;81(2):e115-22. Epub 2011 Feb 12 doi: 10.1016/j.ejrad.2010.12.095. PMID: 21316891
Patel A, Rigsby C, Young L
Pediatr Cardiol 2008 Nov;29(6):1126-8. Epub 2008 Aug 15 doi: 10.1007/s00246-008-9281-5. PMID: 18704552
Martinez-Climent J, Cavalle T, Ferris Tortajada J
Eur J Pediatr Surg 1995 Jun;5(3):156-9. doi: 10.1055/s-2008-1066193. PMID: 7547802

Prognosis

Cohen R, Mirrer B, Loarte P, Navarro V
Clin Cardiol 2013 Jan;36(1):6-9. Epub 2012 Sep 24 doi: 10.1002/clc.22051. PMID: 23007804Free PMC Article
Martinez-Climent J, Cavalle T, Ferris Tortajada J
Eur J Pediatr Surg 1995 Jun;5(3):156-9. doi: 10.1055/s-2008-1066193. PMID: 7547802

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