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Rhegmatogenous retinal detachment

MedGen UID:
489829
Concept ID:
C0271055
Disease or Syndrome; Finding
Synonyms: Retinal detachment due to full thickness retinal tear; Rhegmatogenous Retinal Detachment; rhegmatogenous retinal detachment
SNOMED CT: Rhegmatogenous retinal detachment (19620000); Retinal detachment due to full thickness retinal tear (19620000)
 
HPO: HP:0012230
Monarch Initiative: MONDO:0005464

Definition

A type of retinal detachment associated with a retinal tear, that is, with a break in the retina that allows fluid to pass from the vitreous space into the subretinal space between the sensory retina and the retinal pigment epithelium. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRhegmatogenous retinal detachment

Conditions with this feature

Stickler syndrome, type I, nonsyndromic ocular
MedGen UID:
322820
Concept ID:
C1836080
Disease or Syndrome
Vitreoretinopathy with phalangeal epiphyseal dysplasia
MedGen UID:
343940
Concept ID:
C1852989
Disease or Syndrome
Vitreoretinopathy with phalangeal epiphyseal dysplasia (VPED) is an autosomal dominant disorder characterized by rhegmatogenous retinal detachment, premature arthropathy, and development of phalangeal epiphyseal dysplasia, resulting in brachydactyly. Stature is normal, and high myopia, cleft palate, and midfacial hypoplasia are absent (Richards et al., 2002).

Professional guidelines

PubMed

Shahlaee A, Woeller CF, Philp NJ, Kuriyan AE
Curr Opin Ophthalmol 2022 May 1;33(3):219-227. Epub 2022 Feb 25 doi: 10.1097/ICU.0000000000000840. PMID: 35220328
García-Arumí J, Martínez-Castillo V, Boixadera A, Blasco H, Marticorena J, Zapata MÁ, Macià C, Badal J, Distéfano L, Rafart JM, Berrocal M, Zambrano A, Ruíz-Moreno JM, Figueroa MS
Arch Soc Esp Oftalmol 2013 Jan;88(1):11-35. Epub 2012 Sep 20 doi: 10.1016/j.oftal.2011.10.013. PMID: 23414946
Sodhi A, Leung LS, Do DV, Gower EW, Schein OD, Handa JT
Surv Ophthalmol 2008 Jan-Feb;53(1):50-67. doi: 10.1016/j.survophthal.2007.10.007. PMID: 18191657

Recent clinical studies

Etiology

Mason RH, Minaker SA, Marafon SB, Figueiredo N, Hillier RJ, Muni RH
Surv Ophthalmol 2022 Jul-Aug;67(4):950-964. Epub 2022 Jan 8 doi: 10.1016/j.survophthal.2022.01.002. PMID: 35007619
Pettenkofer M, Chehaibou I, Pole C, Rodriguez M, Rabina G, Kreiger AE, Schwartz SD, Hubschman JP
Graefes Arch Clin Exp Ophthalmol 2022 May;260(5):1509-1516. Epub 2021 Nov 25 doi: 10.1007/s00417-021-05502-8. PMID: 34821991
Chronopoulos A, Hattenbach LO, Schutz JS
Surv Ophthalmol 2021 Jul-Aug;66(4):585-593. Epub 2020 Dec 24 doi: 10.1016/j.survophthal.2020.12.007. PMID: 33359545
Brown KR, Yannuzzi NA, Smiddy WE, Gregori NZ, Berrocal AM, Haddock LJ, Schwartz SG, Lee WH, Sridhar J, Wu DM, Flynn HW Jr, Townsend JH
Ophthalmol Retina 2021 Feb;5(2):178-183. Epub 2020 Jul 14 doi: 10.1016/j.oret.2020.07.007. PMID: 32673672
Colucciello M
Phys Sportsmed 2009 Jun;37(2):59-65. doi: 10.3810/psm.2009.06.1710. PMID: 20048510

Diagnosis

Brown KR, Yannuzzi NA, Smiddy WE, Gregori NZ, Berrocal AM, Haddock LJ, Schwartz SG, Lee WH, Sridhar J, Wu DM, Flynn HW Jr, Townsend JH
Ophthalmol Retina 2021 Feb;5(2):178-183. Epub 2020 Jul 14 doi: 10.1016/j.oret.2020.07.007. PMID: 32673672
Hoogewoud F, Chronopoulos A, Varga Z, Souteyrand G, Thumann G, Schutz JS
Surv Ophthalmol 2016 Mar-Apr;61(2):156-63. Epub 2015 Jul 26 doi: 10.1016/j.survophthal.2015.07.003. PMID: 26216341
El Rayes EN
Dev Ophthalmol 2014;54:135-46. Epub 2014 Aug 26 doi: 10.1159/000360459. PMID: 25196762
Kuhn F, Aylward B
Ophthalmic Res 2014;51(1):15-31. Epub 2013 Oct 22 doi: 10.1159/000355077. PMID: 24158005
Colucciello M
Phys Sportsmed 2009 Jun;37(2):59-65. doi: 10.3810/psm.2009.06.1710. PMID: 20048510

Therapy

Chronopoulos A, Hattenbach LO, Schutz JS
Surv Ophthalmol 2021 Jul-Aug;66(4):585-593. Epub 2020 Dec 24 doi: 10.1016/j.survophthal.2020.12.007. PMID: 33359545
Brown KR, Yannuzzi NA, Smiddy WE, Gregori NZ, Berrocal AM, Haddock LJ, Schwartz SG, Lee WH, Sridhar J, Wu DM, Flynn HW Jr, Townsend JH
Ophthalmol Retina 2021 Feb;5(2):178-183. Epub 2020 Jul 14 doi: 10.1016/j.oret.2020.07.007. PMID: 32673672
Idrees S, Sridhar J, Kuriyan AE
Int Ophthalmol Clin 2019 Winter;59(1):221-240. doi: 10.1097/IIO.0000000000000258. PMID: 30585928Free PMC Article
Hillier RJ, Felfeli T, Berger AR, Wong DT, Altomare F, Dai D, Giavedoni LR, Kertes PJ, Kohly RP, Muni RH
Ophthalmology 2019 Apr;126(4):531-539. Epub 2018 Nov 22 doi: 10.1016/j.ophtha.2018.11.014. PMID: 30468761
Feltgen N, Walter P
Dtsch Arztebl Int 2014 Jan 6;111(1-2):12-21; quiz 22. doi: 10.3238/arztebl.2014.0012. PMID: 24565273Free PMC Article

Prognosis

Xu D, Uhr J, Patel SN, Pandit RR, Jenkins TL, Khan MA, Ho AC
Ophthalmol Retina 2021 Apr;5(4):337-341. Epub 2020 Aug 6 doi: 10.1016/j.oret.2020.08.001. PMID: 32771613
Qureshi MH, Steel DHW
Eye (Lond) 2020 Apr;34(4):616-631. Epub 2019 Oct 1 doi: 10.1038/s41433-019-0575-z. PMID: 31576027Free PMC Article
Assi A, Abdelmassih Y, El-Khoury S
Retina 2018 Feb;38(2):320-324. doi: 10.1097/IAE.0000000000001568. PMID: 28221258
El Rayes EN
Dev Ophthalmol 2014;54:135-46. Epub 2014 Aug 26 doi: 10.1159/000360459. PMID: 25196762
Fraser S, Steel D
BMJ Clin Evid 2010 Nov 24;2010 PMID: 21406128Free PMC Article

Clinical prediction guides

Huang CY, Mikowski M, Wu L
Graefes Arch Clin Exp Ophthalmol 2022 Mar;260(3):711-722. Epub 2021 Oct 12 doi: 10.1007/s00417-021-05448-x. PMID: 34636994
Seider MI, Conell C, Melles RB
Ophthalmology 2022 Jan;129(1):67-72. Epub 2021 Jul 27 doi: 10.1016/j.ophtha.2021.07.020. PMID: 34324945
Hillier RJ, Felfeli T, Berger AR, Wong DT, Altomare F, Dai D, Giavedoni LR, Kertes PJ, Kohly RP, Muni RH
Ophthalmology 2019 Apr;126(4):531-539. Epub 2018 Nov 22 doi: 10.1016/j.ophtha.2018.11.014. PMID: 30468761
Fraser S, Steel D
BMJ Clin Evid 2010 Nov 24;2010 PMID: 21406128Free PMC Article
Steel D, Fraser S
BMJ Clin Evid 2008 Feb 15;2008 PMID: 19450333Free PMC Article

Recent systematic reviews

Mason RH, Minaker SA, Marafon SB, Figueiredo N, Hillier RJ, Muni RH
Surv Ophthalmol 2022 Jul-Aug;67(4):950-964. Epub 2022 Jan 8 doi: 10.1016/j.survophthal.2022.01.002. PMID: 35007619
Steel D
BMJ Clin Evid 2014 Mar 3;2014 PMID: 24807890Free PMC Article
Fraser S, Steel D
BMJ Clin Evid 2010 Nov 24;2010 PMID: 21406128Free PMC Article
Mitry D, Charteris DG, Fleck BW, Campbell H, Singh J
Br J Ophthalmol 2010 Jun;94(6):678-84. Epub 2009 Jun 9 doi: 10.1136/bjo.2009.157727. PMID: 19515646
Steel D, Fraser S
BMJ Clin Evid 2008 Feb 15;2008 PMID: 19450333Free PMC Article

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