U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Placental abruption

MedGen UID:
49
Concept ID:
C0000832
Finding; Pathologic Function
Synonym: Placental abruption (disease)
SNOMED CT: Placental abruption (415105001); Ablatio placentae (415105001); Abruptio placentae (415105001); Premature detachment of normally implanted placenta (415105001); Premature detachment of placenta (415105001); Premature separation of placenta (415105001)
 
HPO: HP:0011419
Monarch Initiative: MONDO:0004846

Definition

Separation of the placenta from the uterus wall before delivery. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPlacental abruption

Conditions with this feature

Fanconi anemia complementation group F
MedGen UID:
854016
Concept ID:
C3469526
Disease or Syndrome
Fanconi anemia (FA) is characterized by physical abnormalities, bone marrow failure, and increased risk for malignancy. Physical abnormalities, present in approximately 75% of affected individuals, include one or more of the following: short stature, abnormal skin pigmentation, skeletal malformations of the upper and/or lower limbs, microcephaly, and ophthalmic and genitourinary tract anomalies. Progressive bone marrow failure with pancytopenia typically presents in the first decade, often initially with thrombocytopenia or leukopenia. The incidence of acute myeloid leukemia is 13% by age 50 years. Solid tumors – particularly of the head and neck, skin, and genitourinary tract – are more common in individuals with FA.

Professional guidelines

PubMed

Brandt JS, Ananth CV
Am J Obstet Gynecol 2023 May;228(5S):S1313-S1329. Epub 2023 Mar 23 doi: 10.1016/j.ajog.2022.06.059. PMID: 37164498Free PMC Article
Stepan H, Galindo A, Hund M, Schlembach D, Sillman J, Surbek D, Vatish M
Ultrasound Obstet Gynecol 2023 Feb;61(2):168-180. doi: 10.1002/uog.26032. PMID: 35816445
Overton E, Tobes D, Lee A
Best Pract Res Clin Anaesthesiol 2022 May;36(1):107-121. Epub 2022 Feb 10 doi: 10.1016/j.bpa.2022.02.003. PMID: 35659948

Recent clinical studies

Therapy

Aguilera J, Konvinse K, Lee A, Maecker H, Prunicki M, Mahalingaiah S, Sampath V, Utz PJ, Yang E, Nadeau KC
Semin Perinatol 2023 Dec;47(8):151838. Epub 2023 Oct 10 doi: 10.1016/j.semperi.2023.151838. PMID: 37858459Free PMC Article
Coutinho LM, Assis WA, Spagnuolo-Souza A, Reis FM
Reprod Sci 2022 Aug;29(8):2145-2151. Epub 2021 Jun 17 doi: 10.1007/s43032-021-00656-6. PMID: 34142343
Ende HB, Lozada MJ, Chestnut DH, Osmundson SS, Walden RL, Shotwell MS, Bauchat JR
Obstet Gynecol 2021 Feb 1;137(2):305-323. doi: 10.1097/AOG.0000000000004228. PMID: 33417319Free PMC Article
Roberge S, Bujold E, Nicolaides KH
Am J Obstet Gynecol 2018 May;218(5):483-489. Epub 2018 Jan 3 doi: 10.1016/j.ajog.2017.12.238. PMID: 29305829
Maraka S, Ospina NM, O'Keeffe DT, Espinosa De Ycaza AE, Gionfriddo MR, Erwin PJ, Coddington CC 3rd, Stan MN, Murad MH, Montori VM
Thyroid 2016 Apr;26(4):580-90. Epub 2016 Mar 3 doi: 10.1089/thy.2015.0418. PMID: 26837268Free PMC Article

Prognosis

Mazza GR, Youssefzadeh AC, Klar M, Kunze M, Matsuzaki S, Mandelbaum RS, Ouzounian JG, Matsuo K
JAMA Netw Open 2022 Nov 1;5(11):e2242842. doi: 10.1001/jamanetworkopen.2022.42842. PMID: 36399343Free PMC Article
Fishel Bartal M, Sibai BM
Am J Obstet Gynecol 2022 Feb;226(2S):S1237-S1253. Epub 2020 Sep 24 doi: 10.1016/j.ajog.2020.09.037. PMID: 32980358
Elkafrawi D, Sisti G, Araji S, Khoury A, Miller J, Rodriguez Echevarria B
Medicina (Kaunas) 2020 Apr 13;56(4) doi: 10.3390/medicina56040174. PMID: 32295061Free PMC Article
Downes KL, Grantz KL, Shenassa ED
Am J Perinatol 2017 Aug;34(10):935-957. Epub 2017 Mar 22 doi: 10.1055/s-0037-1599149. PMID: 28329897Free PMC Article
Oyelese Y, Ananth CV
Obstet Gynecol 2006 Oct;108(4):1005-16. doi: 10.1097/01.AOG.0000239439.04364.9a. PMID: 17012465

Clinical prediction guides

Stepan H, Galindo A, Hund M, Schlembach D, Sillman J, Surbek D, Vatish M
Ultrasound Obstet Gynecol 2023 Feb;61(2):168-180. doi: 10.1002/uog.26032. PMID: 35816445
Elkafrawi D, Sisti G, Araji S, Khoury A, Miller J, Rodriguez Echevarria B
Medicina (Kaunas) 2020 Apr 13;56(4) doi: 10.3390/medicina56040174. PMID: 32295061Free PMC Article
Rammah A, Whitworth KW, Han I, Chan W, Hess JW, Symanski E
Environ Int 2019 Oct;131:105067. Epub 2019 Jul 31 doi: 10.1016/j.envint.2019.105067. PMID: 31376592Free PMC Article
Maraka S, Ospina NM, O'Keeffe DT, Espinosa De Ycaza AE, Gionfriddo MR, Erwin PJ, Coddington CC 3rd, Stan MN, Murad MH, Montori VM
Thyroid 2016 Apr;26(4):580-90. Epub 2016 Mar 3 doi: 10.1089/thy.2015.0418. PMID: 26837268Free PMC Article
Oyelese Y, Ananth CV
Obstet Gynecol 2006 Oct;108(4):1005-16. doi: 10.1097/01.AOG.0000239439.04364.9a. PMID: 17012465

Recent systematic reviews

Rahmati M, Yon DK, Lee SW, Butler L, Koyanagi A, Jacob L, Shin JI, Smith L
Rev Med Virol 2023 May;33(3):e2434. Epub 2023 Mar 10 doi: 10.1002/rmv.2434. PMID: 36896895
Ende HB, Lozada MJ, Chestnut DH, Osmundson SS, Walden RL, Shotwell MS, Bauchat JR
Obstet Gynecol 2021 Feb 1;137(2):305-323. doi: 10.1097/AOG.0000000000004228. PMID: 33417319Free PMC Article
Roberge S, Bujold E, Nicolaides KH
Am J Obstet Gynecol 2018 May;218(5):483-489. Epub 2018 Jan 3 doi: 10.1016/j.ajog.2017.12.238. PMID: 29305829
Downes KL, Grantz KL, Shenassa ED
Am J Perinatol 2017 Aug;34(10):935-957. Epub 2017 Mar 22 doi: 10.1055/s-0037-1599149. PMID: 28329897Free PMC Article
Maraka S, Ospina NM, O'Keeffe DT, Espinosa De Ycaza AE, Gionfriddo MR, Erwin PJ, Coddington CC 3rd, Stan MN, Murad MH, Montori VM
Thyroid 2016 Apr;26(4):580-90. Epub 2016 Mar 3 doi: 10.1089/thy.2015.0418. PMID: 26837268Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...