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Disorder of the genitourinary system

MedGen UID:
508335
•Concept ID:
C0080276
•
Disease or Syndrome
Synonyms: Disease, Genitourinary; Disease, Urogenital; Genitourinary Disease; Genitourinary Diseases; Urogenital Disease; Urogenital Diseases
SNOMED CT: Disorder of the genitourinary system (42030000); Urogenital disorder (42030000); Disorder of genitourinary system (42030000); Syndrome of the genitourinary system (42030000); Urogenital disease (42030000)

Definition

A non-neoplastic or neoplastic disorder that affects the genitourinary system. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDisorder of the genitourinary system

Professional guidelines

PubMed

KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease.
Kidney Disease: Improving Global Outcomes (KDIGO) Diabetes Work Group
Kidney Int 2022 Nov;102(5S):S1-S127. doi: 10.1016/j.kint.2022.06.008. PMID: 36272764
KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases.
Kidney Disease: Improving Global Outcomes (KDIGO) Glomerular Diseases Work Group
Kidney Int 2021 Oct;100(4S):S1-S276. doi: 10.1016/j.kint.2021.05.021. PMID: 34556256
Clinical practice guideline on diagnosis and treatment of hyponatraemia.
Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D, Decaux G, Fenske W, Hoorn EJ, Ichai C, Joannidis M, Soupart A, Zietse R, Haller M, van der Veer S, Van Biesen W, Nagler E; Hyponatraemia Guideline Development Group
Eur J Endocrinol 2014 Mar;170(3):G1-47. Epub 2014 Feb 25 doi: 10.1530/EJE-13-1020. PMID: 24569125

Recent clinical studies

Etiology

Safety of Vaginal Estrogen Therapy for Genitourinary Syndrome of Menopause in Women With a History of Breast Cancer.
Agrawal P, Singh SM, Able C, Dumas K, Kohn J, Kohn TP, Clifton M
Obstet Gynecol 2023 Sep 1;142(3):660-668. Epub 2023 Aug 3 doi: 10.1097/AOG.0000000000005294. PMID: 37535961
Practical Treatment Considerations in the Management of Genitourinary Syndrome of Menopause.
Kagan R, Kellogg-Spadt S, Parish SJ
Drugs Aging 2019 Oct;36(10):897-908. doi: 10.1007/s40266-019-00700-w. PMID: 31452067Free PMC Article
The Burden of Candidate Pathogenic Variants for Kidney and Genitourinary Disorders Emerging From Exome Sequencing.
Rasouly HM, Groopman EE, Heyman-Kantor R, Fasel DA, Mitrotti A, Westland R, Bier L, Weng C, Ren Z, Copeland B, Krithivasan P, Chung WK, Sanna-Cherchi S, Goldstein DB, Gharavi AG
Ann Intern Med 2019 Jan 1;170(1):11-21. Epub 2018 Nov 27 doi: 10.7326/M18-1241. PMID: 30476936
An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction.
Haylen BT, de Ridder D, Freeman RM, Swift SE, Berghmans B, Lee J, Monga A, Petri E, Rizk DE, Sand PK, Schaer GN; International Urogynecological Association; International Continence Society
Neurourol Urodyn 2010;29(1):4-20. doi: 10.1002/nau.20798. PMID: 19941278
Hematuria.
Sokolosky MC
Emerg Med Clin North Am 2001 Aug;19(3):621-32. doi: 10.1016/s0733-8627(05)70206-6. PMID: 11554278

Diagnosis

Genitourinary Syndrome of Menopause.
Cox S, Nasseri R, Rubin RS, Santiago-Lastra Y
Med Clin North Am 2023 Mar;107(2):357-369. doi: 10.1016/j.mcna.2022.10.017. PMID: 36759102
Practical Treatment Considerations in the Management of Genitourinary Syndrome of Menopause.
Kagan R, Kellogg-Spadt S, Parish SJ
Drugs Aging 2019 Oct;36(10):897-908. doi: 10.1007/s40266-019-00700-w. PMID: 31452067Free PMC Article
An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction.
Haylen BT, de Ridder D, Freeman RM, Swift SE, Berghmans B, Lee J, Monga A, Petri E, Rizk DE, Sand PK, Schaer GN; International Urogynecological Association; International Continence Society
Neurourol Urodyn 2010;29(1):4-20. doi: 10.1002/nau.20798. PMID: 19941278
Hematuria.
Sokolosky MC
Emerg Med Clin North Am 2001 Aug;19(3):621-32. doi: 10.1016/s0733-8627(05)70206-6. PMID: 11554278
Low back pain.
Deyo RA, Weinstein JN
N Engl J Med 2001 Feb 1;344(5):363-70. doi: 10.1056/NEJM200102013440508. PMID: 11172169

Therapy

Physical methods for the treatment of genitourinary syndrome of menopause: A systematic review.
Sarmento ACA, Lírio JF, Medeiros KS, Marconi C, Costa APF, Crispim JC, Gonçalves AK
Int J Gynaecol Obstet 2021 May;153(2):200-219. Epub 2021 Feb 22 doi: 10.1002/ijgo.13561. PMID: 33354773
Critical analysis of methods for assessing genitourinary syndrome of menopause used in clinical trials.
Lima SMRR, Honorato JV
Menopause 2019 Dec;26(12):1436-1442. doi: 10.1097/GME.0000000000001406. PMID: 31644509
Practical Treatment Considerations in the Management of Genitourinary Syndrome of Menopause.
Kagan R, Kellogg-Spadt S, Parish SJ
Drugs Aging 2019 Oct;36(10):897-908. doi: 10.1007/s40266-019-00700-w. PMID: 31452067Free PMC Article
Genitourinary pathogens and preterm birth.
Cunnington M, Kortsalioudaki C, Heath P
Curr Opin Infect Dis 2013 Jun;26(3):219-30. doi: 10.1097/QCO.0b013e328360dc31. PMID: 23612500
Recurrent spontaneous abortion.
McIntyre JA, Coulam CB, Faulk WP
Am J Reprod Immunol 1989 Nov-Dec;21(3-4):100-4. doi: 10.1111/j.1600-0897.1989.tb01011.x. PMID: 2534830

Prognosis

Epidemiology and definition of PPH worldwide.
Bláha J, Bartošová T
Best Pract Res Clin Anaesthesiol 2022 Dec;36(3-4):325-339. Epub 2022 Nov 13 doi: 10.1016/j.bpa.2022.11.001. PMID: 36513428
Worldwide trends in cervical cancer incidence and mortality, with predictions for the next 15 years.
Lin S, Gao K, Gu S, You L, Qian S, Tang M, Wang J, Chen K, Jin M
Cancer 2021 Nov 1;127(21):4030-4039. Epub 2021 Aug 9 doi: 10.1002/cncr.33795. PMID: 34368955
Trends in cervical cancer mortality in China from 1989 to 2018: an age-period-cohort study and Joinpoint analysis.
Guo M, Xu J, Du J
BMC Public Health 2021 Jul 6;21(1):1329. doi: 10.1186/s12889-021-11401-8. PMID: 34229639Free PMC Article
Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis.
Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, Bray F
Lancet Glob Health 2020 Feb;8(2):e191-e203. Epub 2019 Dec 4 doi: 10.1016/S2214-109X(19)30482-6. PMID: 31812369Free PMC Article
The frequency and outcome of lupus nephritis: results from an international inception cohort study.
Hanly JG, O'Keeffe AG, Su L, Urowitz MB, Romero-Diaz J, Gordon C, Bae SC, Bernatsky S, Clarke AE, Wallace DJ, Merrill JT, Isenberg DA, Rahman A, Ginzler EM, Fortin P, Gladman DD, Sanchez-Guerrero J, Petri M, Bruce IN, Dooley MA, Ramsey-Goldman R, Aranow C, Alarcón GS, Fessler BJ, Steinsson K, Nived O, Sturfelt GK, Manzi S, Khamashta MA, van Vollenhoven RF, Zoma AA, Ramos-Casals M, Ruiz-Irastorza G, Lim SS, Stoll T, Inanc M, Kalunian KC, Kamen DL, Maddison P, Peschken CA, Jacobsen S, Askanase A, Theriault C, Thompson K, Farewell V
Rheumatology (Oxford) 2016 Feb;55(2):252-62. Epub 2015 Sep 5 doi: 10.1093/rheumatology/kev311. PMID: 26342222Free PMC Article

Clinical prediction guides

Simulating and estimating agreement in the presence of multiple raters and covariates.
McKenzie KA, Mahnken JD
Stat Med 2023 May 20;42(11):1687-1698. Epub 2023 Mar 5 doi: 10.1002/sim.9694. PMID: 36872574Free PMC Article
Critical analysis of methods for assessing genitourinary syndrome of menopause used in clinical trials.
Lima SMRR, Honorato JV
Menopause 2019 Dec;26(12):1436-1442. doi: 10.1097/GME.0000000000001406. PMID: 31644509
Multiparametric Magnetic Resonance Imaging for Bladder Cancer: Development of VI-RADS (Vesical Imaging-Reporting And Data System).
Panebianco V, Narumi Y, Altun E, Bochner BH, Efstathiou JA, Hafeez S, Huddart R, Kennish S, Lerner S, Montironi R, Muglia VF, Salomon G, Thomas S, Vargas HA, Witjes JA, Takeuchi M, Barentsz J, Catto JWF
Eur Urol 2018 Sep;74(3):294-306. Epub 2018 May 10 doi: 10.1016/j.eururo.2018.04.029. PMID: 29755006Free PMC Article
An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction.
Haylen BT, de Ridder D, Freeman RM, Swift SE, Berghmans B, Lee J, Monga A, Petri E, Rizk DE, Sand PK, Schaer GN; International Urogynecological Association; International Continence Society
Neurourol Urodyn 2010;29(1):4-20. doi: 10.1002/nau.20798. PMID: 19941278
Amniotic fluid assessment.
Williams K
Obstet Gynecol Surv 1993 Dec;48(12):795-800. doi: 10.1097/00006254-199312000-00005. PMID: 8309662

Recent systematic reviews

European Association of Urology Guidelines on the Diagnosis and Management of Female Non-neurogenic Lower Urinary Tract Symptoms. Part 1: Diagnostics, Overactive Bladder, Stress Urinary Incontinence, and Mixed Urinary Incontinence.
Nambiar AK, Arlandis S, Bø K, Cobussen-Boekhorst H, Costantini E, de Heide M, Farag F, Groen J, Karavitakis M, Lapitan MC, Manso M, Arteaga SM, Riogh ANA, O'Connor E, Omar MI, Peyronnet B, Phé V, Sakalis VI, Sihra N, Tzelves L, van Poelgeest-Pomfret ML, van den Bos TWL, van der Vaart H, Harding CK
Eur Urol 2022 Jul;82(1):49-59. Epub 2022 Feb 23 doi: 10.1016/j.eururo.2022.01.045. PMID: 35216856
The Effect of Uterine Adenomyosis on IVF Outcomes: a Systematic Review and Meta-analysis.
Cozzolino M, Tartaglia S, Pellegrini L, Troiano G, Rizzo G, Petraglia F
Reprod Sci 2022 Nov;29(11):3177-3193. Epub 2022 Jan 3 doi: 10.1007/s43032-021-00818-6. PMID: 34981458
Pelvic floor muscle training for preventing and treating urinary and faecal incontinence in antenatal and postnatal women.
Woodley SJ, Lawrenson P, Boyle R, Cody JD, Mørkved S, Kernohan A, Hay-Smith EJC
Cochrane Database Syst Rev 2020 May 6;5(5):CD007471. doi: 10.1002/14651858.CD007471.pub4. PMID: 32378735Free PMC Article
INFERTILITY AND SEXUAL DYSFUNCTIONS: A SYSTEMATIC LITERATURE REVIEW.
Starc A, Trampuš M, Pavan Jukić D, Rotim C, Jukić T, Polona Mivšek A
Acta Clin Croat 2019 Sep;58(3):508-515. doi: 10.20471/acc.2019.58.03.15. PMID: 31969764Free PMC Article
Prevalence of antenatal and postnatal anxiety: systematic review and meta-analysis.
Dennis CL, Falah-Hassani K, Shiri R
Br J Psychiatry 2017 May;210(5):315-323. Epub 2017 Mar 16 doi: 10.1192/bjp.bp.116.187179. PMID: 28302701

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