U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Nummular eczema

MedGen UID:
508353
•Concept ID:
C0085656
•
Disease or Syndrome
Synonyms: Discoid eczema; Nummular dermatitis; Nummular eczematous dermatitis
SNOMED CT: Nummular eczema (81418003); Nummular dermatitis (81418003); Nummular eczematous dermatitis (81418003); Discoid eczema (81418003)
 
HPO: HP:0033120

Definition

A type of eczema characterized by pruritic coin-shaped patches on the skin. Nummular eczema most commonly occurs on the extremities, particularly the legs, but may occur anywhere on the trunk, hands, or feet [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNummular eczema

Professional guidelines

PubMed

Effectiveness of dupilumab for the treatment of nummular eczema phenotype of atopic dermatitis in adults.
Patruno C, Stingeni L, Hansel K, Ferrucci SM, Tavecchio S, Fabbrocini G, Nisticò SP, Foti C, De Prezzo S, Napolitano M
Dermatol Ther 2020 May;33(3):e13290. Epub 2020 Mar 11 doi: 10.1111/dth.13290. PMID: 32125741
Annular Lesions: Diagnosis and Treatment.
Trayes KP, Savage K, Studdiford JS
Am Fam Physician 2018 Sep 1;98(5):283-291. PMID: 30216021
Pityriasis Rosea: Diagnosis and Treatment.
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241

Recent clinical studies

Etiology

Association of Adult Atopic Dermatitis Severity With Bacterial, Viral, and Fungal Skin Infections.
Rios-Duarte JA, Silverberg JI
Dermatitis 2023 Mar-Apr;34(2):120-126. Epub 2023 Jan 19 doi: 10.1089/derm.2022.29006.jrd. PMID: 36917529
Prevalence and trend of allergen sensitization in patients with nummular (discoid) eczema referred for patch testing: North American Contact Dermatitis Group data, 2001-2016.
Silverberg JI, Hou A, Warshaw EM, Maibach HI, Belsito DV, DeKoven JG, Zug KA, Taylor JS, Sasseville D, Fransway AF, DeLeo VA, Pratt MD, Reeder MJ, Atwater AR, Fowler JF Jr, Zirwas MJ, Marks JG Jr
Contact Dermatitis 2021 Jul;85(1):46-57. Epub 2021 Mar 16 doi: 10.1111/cod.13824. PMID: 33634511
FACTORS CONTRIBUTING TO CHRONIC URTICARIA/ANGIOEDEMA AND NUMMULAR ECZEMA RESOLUTION - WHICH FINDINGS ARE CRUCIAL?
Lugović-Mihić L, Bukvić I, Bulat V, Japundžić I
Acta Clin Croat 2019 Dec;58(4):595-603. doi: 10.20471/acc.2019.58.04.05. PMID: 32595243Free PMC Article
Methotrexate for severe nummular eczema in children: Efficacy and tolerability in a retrospective study of 28 patients.
Knöpfel N, Noguera-Morel L, Hernández-Martín A, Torrelo A
Pediatr Dermatol 2018 Sep;35(5):611-615. Epub 2018 Jun 26 doi: 10.1111/pde.13568. PMID: 29943852
Nummular eczema and contact allergy: a retrospective study.
Bonamonte D, Foti C, Vestita M, Ranieri LD, Angelini G
Dermatitis 2012 Jul-Aug;23(4):153-7. doi: 10.1097/DER.0b013e318260d5a0. PMID: 22828253

Diagnosis

Clinical phenotypes of adult atopic dermatitis and related therapies.
Patruno C, Potestio L, Napolitano M
Curr Opin Allergy Clin Immunol 2022 Aug 1;22(4):242-249. Epub 2022 Jun 28 doi: 10.1097/ACI.0000000000000837. PMID: 35786802
Nummular Eczema: An Updated Review.
Leung AKC, Lam JM, Leong KF, Leung AAM, Wong AHC, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2020;14(2):146-155. doi: 10.2174/1872213X14666200810152246. PMID: 32778043
Annular Lesions: Diagnosis and Treatment.
Trayes KP, Savage K, Studdiford JS
Am Fam Physician 2018 Sep 1;98(5):283-291. PMID: 30216021
Pityriasis Rosea: Diagnosis and Treatment.
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241
Nummular eczema.
Halberg M
J Emerg Med 2012 Nov;43(5):e327-8. Epub 2011 Jun 29 doi: 10.1016/j.jemermed.2011.05.031. PMID: 21719233

Therapy

Clinical phenotypes of adult atopic dermatitis and related therapies.
Patruno C, Potestio L, Napolitano M
Curr Opin Allergy Clin Immunol 2022 Aug 1;22(4):242-249. Epub 2022 Jun 28 doi: 10.1097/ACI.0000000000000837. PMID: 35786802
Dupilumab: A Review of Present Indications and Off-Label Uses.
Muñoz-Bellido FJ, Moreno E, Dávila I
J Investig Allergol Clin Immunol 2022 Apr 19;32(2):97-115. Epub 2021 Mar 3 doi: 10.18176/jiaci.0682. PMID: 33661102
Nummular Eczema: An Updated Review.
Leung AKC, Lam JM, Leong KF, Leung AAM, Wong AHC, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2020;14(2):146-155. doi: 10.2174/1872213X14666200810152246. PMID: 32778043
Pityriasis Rosea: Diagnosis and Treatment.
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241
Nummular eczema.
Halberg M
J Emerg Med 2012 Nov;43(5):e327-8. Epub 2011 Jun 29 doi: 10.1016/j.jemermed.2011.05.031. PMID: 21719233

Prognosis

Discoid (nummular) eczema in the paediatric setting - An Australian/New Zealand narrative.
McWhirter S, Foster R, Halbert A, Miller R, Morgan VA, Rademaker M, Robertson S, Scardamaglia L, Warren L, Wong LC, Zappala T, Orchard D
Australas J Dermatol 2022 Nov;63(4):e289-e296. Epub 2022 Sep 4 doi: 10.1111/ajd.13915. PMID: 36057946
Nummular Eczema: An Updated Review.
Leung AKC, Lam JM, Leong KF, Leung AAM, Wong AHC, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2020;14(2):146-155. doi: 10.2174/1872213X14666200810152246. PMID: 32778043
Pityriasis Rosea: Diagnosis and Treatment.
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241
Proteomic Approaches to Biomarker Discovery in Cutaneous T-Cell Lymphoma.
Ion A, Popa IM, Papagheorghe LM, Lisievici C, Lupu M, Voiculescu V, Caruntu C, Boda D
Dis Markers 2016;2016:9602472. Epub 2016 Oct 16 doi: 10.1155/2016/9602472. PMID: 27821903Free PMC Article
Clinical features and aggravating factors in nummular eczema in Thais.
Jiamton S, Tangjaturonrusamee C, Kulthanan K
Asian Pac J Allergy Immunol 2013 Mar;31(1):36-42. PMID: 23517392

Clinical prediction guides

Higher Expression of Lympho-epithelial Kazal-type-Related Inhibitor-1 Fragments and Decreased Desquamation in the Lesional Skin of Nummular Eczema.
Montenegro SE, Oh JH, Suh JH, Mun JH, Chung JH
Acta Derm Venereol 2024 Mar 29;104:adv188636. doi: 10.2340/actadv.v104.18636. PMID: 38551375Free PMC Article
Nummular Eczema: An Updated Review.
Leung AKC, Lam JM, Leong KF, Leung AAM, Wong AHC, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2020;14(2):146-155. doi: 10.2174/1872213X14666200810152246. PMID: 32778043
Effectiveness of dupilumab for the treatment of nummular eczema phenotype of atopic dermatitis in adults.
Patruno C, Stingeni L, Hansel K, Ferrucci SM, Tavecchio S, Fabbrocini G, Nisticò SP, Foti C, De Prezzo S, Napolitano M
Dermatol Ther 2020 May;33(3):e13290. Epub 2020 Mar 11 doi: 10.1111/dth.13290. PMID: 32125741
Proteomic Approaches to Biomarker Discovery in Cutaneous T-Cell Lymphoma.
Ion A, Popa IM, Papagheorghe LM, Lisievici C, Lupu M, Voiculescu V, Caruntu C, Boda D
Dis Markers 2016;2016:9602472. Epub 2016 Oct 16 doi: 10.1155/2016/9602472. PMID: 27821903Free PMC Article
Clinical features and aggravating factors in nummular eczema in Thais.
Jiamton S, Tangjaturonrusamee C, Kulthanan K
Asian Pac J Allergy Immunol 2013 Mar;31(1):36-42. PMID: 23517392

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...