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Disorder of orbital region

MedGen UID:
5092
Concept ID:
C0015397
Disease or Syndrome
Synonym: Disease of orbital region
SNOMED CT: Disorder of eye (371405004); Disorder of eye region (371409005); Disease of eyeball (371405004); Disorder of globe (371405004); Disorder of eyeball (371405004); Ophthalmological disorder (371409005); Disorder of orbital region (371409005); Eye disorder (371405004); Disorder of eye proper (371405004)
 
Monarch Initiative: MONDO:0002022

Definition

A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Disorder of orbital region

Professional guidelines

PubMed

Banwell B, Bennett JL, Marignier R, Kim HJ, Brilot F, Flanagan EP, Ramanathan S, Waters P, Tenembaum S, Graves JS, Chitnis T, Brandt AU, Hemingway C, Neuteboom R, Pandit L, Reindl M, Saiz A, Sato DK, Rostasy K, Paul F, Pittock SJ, Fujihara K, Palace J
Lancet Neurol 2023 Mar;22(3):268-282. Epub 2023 Jan 24 doi: 10.1016/S1474-4422(22)00431-8. PMID: 36706773
Stein JD, Khawaja AP, Weizer JS
JAMA 2021 Jan 12;325(2):164-174. doi: 10.1001/jama.2020.21899. PMID: 33433580
van Rijssen TJ, van Dijk EHC, Yzer S, Ohno-Matsui K, Keunen JEE, Schlingemann RO, Sivaprasad S, Querques G, Downes SM, Fauser S, Hoyng CB, Piccolino FC, Chhablani JK, Lai TYY, Lotery AJ, Larsen M, Holz FG, Freund KB, Yannuzzi LA, Boon CJF
Prog Retin Eye Res 2019 Nov;73:100770. Epub 2019 Jul 15 doi: 10.1016/j.preteyeres.2019.07.003. PMID: 31319157

Recent clinical studies

Etiology

Gaballa SA, Kompella UB, Elgarhy O, Alqahtani AM, Pierscionek B, Alany RG, Abdelkader H
Drug Deliv Transl Res 2021 Jun;11(3):866-893. doi: 10.1007/s13346-020-00843-z. PMID: 32901367
Dammacco R
Clin Exp Med 2018 May;18(2):135-149. Epub 2017 Dec 14 doi: 10.1007/s10238-017-0479-9. PMID: 29243035
Solebo AL, Teoh L, Rahi J
Arch Dis Child 2017 Sep;102(9):853-857. Epub 2017 May 2 doi: 10.1136/archdischild-2016-310532. PMID: 28465303
Milston R, Madigan MC, Sebag J
Surv Ophthalmol 2016 Mar-Apr;61(2):211-27. Epub 2015 Dec 8 doi: 10.1016/j.survophthal.2015.11.008. PMID: 26679984
Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P
Ophthalmology 2013 Dec;120(12):2611-2619. Epub 2013 Sep 17 doi: 10.1016/j.ophtha.2013.07.042. PMID: 24053995

Diagnosis

Couser NL, Brooks BP, Drack AV, Shankar SP
Ophthalmic Genet 2021 Apr;42(2):110-113. Epub 2021 Jan 12 doi: 10.1080/13816810.2020.1868011. PMID: 33432855
Shah SM, Khanna CL
Mayo Clin Proc 2020 May;95(5):1050-1058. doi: 10.1016/j.mayocp.2020.03.018. PMID: 32370836
Muthiah S, Radhakrishnan N
Indian J Pediatr 2017 Dec;84(12):945-952. Epub 2017 Jul 14 doi: 10.1007/s12098-017-2409-y. PMID: 28707045
Shao L, Wei W
Chin Med J (Engl) 2014;127(8):1566-71. PMID: 24762607
Carruthers J
Curr Opin Ophthalmol 1996 Oct;7(5):3-7. doi: 10.1097/00055735-199610000-00002. PMID: 10165105

Therapy

Vieira JM, Ricardo OMP, Hannas CM, Kanadani TCM, Prata TDS, Kanadani FN
Rev Assoc Med Bras (1992) 2020 Apr;66(4):534-540. doi: 10.1590/1806-9282.66.4.534. PMID: 32578792
Laihia J, Kaarniranta K
Biomolecules 2020 May 25;10(5) doi: 10.3390/biom10050809. PMID: 32466265Free PMC Article
Clark SJ, Bishop PN
Semin Immunopathol 2018 Jan;40(1):65-74. Epub 2017 Sep 25 doi: 10.1007/s00281-017-0649-6. PMID: 28948331Free PMC Article
Chan L, Mahajan VB, Tsang SH
Yale J Biol Med 2017 Dec;90(4):523-532. Epub 2017 Dec 19 PMID: 29259518Free PMC Article
Tam C, Wong JH, Cheung RCF, Zuo T, Ng TB
Appl Microbiol Biotechnol 2017 Oct;101(19):7091-7111. Epub 2017 Aug 8 doi: 10.1007/s00253-017-8433-z. PMID: 28791440

Prognosis

Feng J, Huang C, Liang L, Li C, Wang X, Ma J, Guan X, Jiang B, Huang S, Qin P
J Am Med Dir Assoc 2023 Sep;24(9):1363-1373.e6. Epub 2023 Jul 29 doi: 10.1016/j.jamda.2023.06.025. PMID: 37527793
Muthiah S, Radhakrishnan N
Indian J Pediatr 2017 Dec;84(12):945-952. Epub 2017 Jul 14 doi: 10.1007/s12098-017-2409-y. PMID: 28707045
Grzybowski A, Nita M, Virmond M
Clin Dermatol 2015 Jan-Feb;33(1):79-89. doi: 10.1016/j.clindermatol.2014.07.003. PMID: 25432813
Hodge C, Lawless M
Aust Fam Physician 2008 Jul;37(7):506-9. PMID: 18592066
Margolis R, Lowder CY
Curr Opin Ophthalmol 2007 Nov;18(6):470-5. doi: 10.1097/ICU.0b013e3282f06c6c. PMID: 18162998

Clinical prediction guides

Guggenheim JA, Ghorbani Mojarrad N, Williams C, Flitcroft DI
Ophthalmic Physiol Opt 2017 Sep;37(5):549-556. doi: 10.1111/opo.12403. PMID: 28836387
Ohno-Matsui K, Kawasaki R, Jonas JB, Cheung CM, Saw SM, Verhoeven VJ, Klaver CC, Moriyama M, Shinohara K, Kawasaki Y, Yamazaki M, Meuer S, Ishibashi T, Yasuda M, Yamashita H, Sugano A, Wang JJ, Mitchell P, Wong TY; META-analysis for Pathologic Myopia (META-PM) Study Group
Am J Ophthalmol 2015 May;159(5):877-83.e7. Epub 2015 Jan 26 doi: 10.1016/j.ajo.2015.01.022. PMID: 25634530
Shao L, Wei W
Chin Med J (Engl) 2014;127(8):1566-71. PMID: 24762607
Parikh R, Mathai A, Parikh S, Chandra Sekhar G, Thomas R
Indian J Ophthalmol 2008 Jan-Feb;56(1):45-50. doi: 10.4103/0301-4738.37595. PMID: 18158403Free PMC Article
Lancet 1990 May 5;335(8697):1078-80. PMID: 1970380

Recent systematic reviews

Zhu Z, Chen Y, Tan Z, Xiong R, McGuinness MB, Müller A
Br J Ophthalmol 2023 Feb;107(2):160-166. Epub 2021 Nov 29 doi: 10.1136/bjophthalmol-2021-319306. PMID: 34844916
Singh S, McGuinness MB, Anderson AJ, Downie LE
Ophthalmology 2022 Oct;129(10):1192-1215. Epub 2022 May 18 doi: 10.1016/j.ophtha.2022.05.009. PMID: 35597519
Chan HN, Zhang XJ, Ling XT, Bui CH, Wang YM, Ip P, Chu WK, Chen LJ, Tham CC, Yam JC, Pang CP
Int J Mol Sci 2022 Apr 11;23(8) doi: 10.3390/ijms23084226. PMID: 35457041Free PMC Article
GBD 2019 Blindness and Vision Impairment Collaborators; Vision Loss Expert Group of the Global Burden of Disease Study
Lancet Glob Health 2021 Feb;9(2):e144-e160. Epub 2020 Dec 1 doi: 10.1016/S2214-109X(20)30489-7. PMID: 33275949Free PMC Article
Azari AA, Barney NP
JAMA 2013 Oct 23;310(16):1721-9. doi: 10.1001/jama.2013.280318. PMID: 24150468Free PMC Article

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