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Disorder of eye region

MedGen UID:
5092
•Concept ID:
C0015397
•
Disease or Syndrome
Synonyms: Eye Disease; Eye Diseases; Eye Disorder; Eye Disorders
SNOMED CT: Disorder of eye (371405004); Disorder of eye region (371409005); Disease of eyeball (371405004); Disorder of globe (371405004); Disorder of eyeball (371405004); Ophthalmological disorder (371409005); Disorder of orbital region (371409005); Eye disorder (371405004); Disorder of eye proper (371405004)

Definition

A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDisorder of eye region

Professional guidelines

PubMed

Diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease: International MOGAD Panel proposed criteria.
Banwell B, Bennett JL, Marignier R, Kim HJ, Brilot F, Flanagan EP, Ramanathan S, Waters P, Tenembaum S, Graves JS, Chitnis T, Brandt AU, Hemingway C, Neuteboom R, Pandit L, Reindl M, Saiz A, Sato DK, Rostasy K, Paul F, Pittock SJ, Fujihara K, Palace J
Lancet Neurol 2023 Mar;22(3):268-282. Epub 2023 Jan 24 doi: 10.1016/S1474-4422(22)00431-8. PMID: 36706773
Glaucoma in Adults-Screening, Diagnosis, and Management: A Review.
Stein JD, Khawaja AP, Weizer JS
JAMA 2021 Jan 12;325(2):164-174. doi: 10.1001/jama.2020.21899. PMID: 33433580
Treatment of Diabetes in Older Adults: An Endocrine Society* Clinical Practice Guideline.
LeRoith D, Biessels GJ, Braithwaite SS, Casanueva FF, Draznin B, Halter JB, Hirsch IB, McDonnell ME, Molitch ME, Murad MH, Sinclair AJ
J Clin Endocrinol Metab 2019 May 1;104(5):1520-1574. doi: 10.1210/jc.2019-00198. PMID: 30903688Free PMC Article

Recent clinical studies

Etiology

Corticosteroids in ophthalmology: drug delivery innovations, pharmacology, clinical applications, and future perspectives.
Gaballa SA, Kompella UB, Elgarhy O, Alqahtani AM, Pierscionek B, Alany RG, Abdelkader H
Drug Deliv Transl Res 2021 Jun;11(3):866-893. doi: 10.1007/s13346-020-00843-z. PMID: 32901367
Axenfeld-Rieger syndrome.
Seifi M, Walter MA
Clin Genet 2018 Jun;93(6):1123-1130. Epub 2018 Jan 25 doi: 10.1111/cge.13148. PMID: 28972279
Epidemiology of blindness in children.
Solebo AL, Teoh L, Rahi J
Arch Dis Child 2017 Sep;102(9):853-857. Epub 2017 May 2 doi: 10.1136/archdischild-2016-310532. PMID: 28465303
Vitreous floaters: Etiology, diagnostics, and management.
Milston R, Madigan MC, Sebag J
Surv Ophthalmol 2016 Mar-Apr;61(2):211-27. Epub 2015 Dec 8 doi: 10.1016/j.survophthal.2015.11.008. PMID: 26679984
The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole.
Duker JS, Kaiser PK, Binder S, de Smet MD, Gaudric A, Reichel E, Sadda SR, Sebag J, Spaide RF, Stalmans P
Ophthalmology 2013 Dec;120(12):2611-2619. Epub 2013 Sep 17 doi: 10.1016/j.ophtha.2013.07.042. PMID: 24053995

Diagnosis

Congenital alacrima.
Zhao Z, Allen RC
Orbit 2022 Apr;41(2):162-169. Epub 2021 Sep 5 doi: 10.1080/01676830.2021.1974057. PMID: 34486478
Ocular complications of atopic dermatitis.
Hsu JI, Pflugfelder SC, Kim SJ
Cutis 2019 Sep;104(3):189-193. PMID: 31675394
Axenfeld-Rieger syndrome.
Seifi M, Walter MA
Clin Genet 2018 Jun;93(6):1123-1130. Epub 2018 Jan 25 doi: 10.1111/cge.13148. PMID: 28972279
Ocular Emergencies: Red Eye.
Tarff A, Behrens A
Med Clin North Am 2017 May;101(3):615-639. Epub 2017 Mar 8 doi: 10.1016/j.mcna.2016.12.013. PMID: 28372717
Rhegmatogenous retinal detachment--an ophthalmologic emergency.
Feltgen N, Walter P
Dtsch Arztebl Int 2014 Jan 6;111(1-2):12-21; quiz 22. doi: 10.3238/arztebl.2014.0012. PMID: 24565273Free PMC Article

Therapy

Endpoints for extraintestinal manifestations in inflammatory bowel disease trials: the EXTRA consensus from the International Organization for the Study of Inflammatory Bowel Diseases.
Guillo L, Abreu M, Panaccione R, Sandborn WJ, Azevedo VF, Gensler L, Moghaddam B, Ahuja V, Ali SA, Allez M, Ananthakrishnan AN, Bhattacharya A, Dubinsky M, Griffiths A, Hart A, Korelitz B, Kotze PG, Koutroubakis IE, Lakatos PL, Lindsay JO, Magro F, Mantzaris GJ, Ng SC, O'Morain C, Panés J, Parigi T, Ran Z, Rogler G, Rubin DT, Sachar DB, Siegmund B, Steinwurz F, Tysk C, Vavricka S, Verstraete SG, Brezin AP, Haemel AK, Dignass A, Sands BE, Danese S, Peyrin-Biroulet L
Lancet Gastroenterol Hepatol 2022 Mar;7(3):254-261. Epub 2022 Jan 17 doi: 10.1016/S2468-1253(21)00297-1. PMID: 35051383
Efficacy of combined orthokeratology and 0.01% atropine for myopia control: the study protocol for a randomized, controlled, double-blind, and multicenter trial.
Yuan Y, Zhu C, Liu M, Zhou Y, Yang X, Zheng B, Li Z, Mao X, Ke B
Trials 2021 Dec 1;22(1):863. doi: 10.1186/s13063-021-05825-1. PMID: 34852833Free PMC Article
Trehalose for Ocular Surface Health.
Laihia J, Kaarniranta K
Biomolecules 2020 May 25;10(5) doi: 10.3390/biom10050809. PMID: 32466265Free PMC Article
Progress in treating inherited retinal diseases: Early subretinal gene therapy clinical trials and candidates for future initiatives.
Garafalo AV, Cideciyan AV, Héon E, Sheplock R, Pearson A, WeiYang Yu C, Sumaroka A, Aguirre GD, Jacobson SG
Prog Retin Eye Res 2020 Jul;77:100827. Epub 2019 Dec 30 doi: 10.1016/j.preteyeres.2019.100827. PMID: 31899291Free PMC Article
Non-steroidal anti-inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract surgery.
Juthani VV, Clearfield E, Chuck RS
Cochrane Database Syst Rev 2017 Jul 3;7(7):CD010516. doi: 10.1002/14651858.CD010516.pub2. PMID: 28670710Free PMC Article

Prognosis

A Review of Capture-recapture Methods and Its Possibilities in Ophthalmology and Vision Sciences.
Ramos PL, Sousa I, Santana R, Morgan WH, Gordon K, Crewe J, Rocha-Sousa A, Macedo AF
Ophthalmic Epidemiol 2020 Aug;27(4):310-324. Epub 2020 May 3 doi: 10.1080/09286586.2020.1749286. PMID: 32363970
Toxic anterior segment syndrome-an updated review.
Park CY, Lee JK, Chuck RS
BMC Ophthalmol 2018 Oct 25;18(1):276. doi: 10.1186/s12886-018-0939-3. PMID: 30359246Free PMC Article
Incidence of cataract following implantation of a posterior-chamber phakic lens ICL (Implantable Collamer Lens) - long-term results.
Kocová H, Vlková E, Michalcová L, Rybárová N, Motyka O
Cesk Slov Oftalmol 2017 Fall;73(3):87-93. PMID: 29394074
Management of Extraocular Infections.
Muthiah S, Radhakrishnan N
Indian J Pediatr 2017 Dec;84(12):945-952. Epub 2017 Jul 14 doi: 10.1007/s12098-017-2409-y. PMID: 28707045
Ocular leprosy.
Grzybowski A, Nita M, Virmond M
Clin Dermatol 2015 Jan-Feb;33(1):79-89. doi: 10.1016/j.clindermatol.2014.07.003. PMID: 25432813

Clinical prediction guides

Congenital Stationary Night Blindness: Clinical and Genetic Features.
Kim AH, Liu PK, Chang YH, Kang EY, Wang HH, Chen N, Tseng YJ, Seo GH, Lee H, Liu L, Chao AN, Chen KJ, Hwang YS, Wu WC, Lai CC, Tsang SH, Hsiao MC, Wang NK
Int J Mol Sci 2022 Nov 29;23(23) doi: 10.3390/ijms232314965. PMID: 36499293Free PMC Article
Ocular features in Alport syndrome: pathogenesis and clinical significance.
Savige J, Sheth S, Leys A, Nicholson A, Mack HG, Colville D
Clin J Am Soc Nephrol 2015 Apr 7;10(4):703-9. Epub 2015 Feb 3 doi: 10.2215/CJN.10581014. PMID: 25649157Free PMC Article
International photographic classification and grading system for myopic maculopathy.
Ohno-Matsui K, Kawasaki R, Jonas JB, Cheung CM, Saw SM, Verhoeven VJ, Klaver CC, Moriyama M, Shinohara K, Kawasaki Y, Yamazaki M, Meuer S, Ishibashi T, Yasuda M, Yamashita H, Sugano A, Wang JJ, Mitchell P, Wong TY; META-analysis for Pathologic Myopia (META-PM) Study Group
Am J Ophthalmol 2015 May;159(5):877-83.e7. Epub 2015 Jan 26 doi: 10.1016/j.ajo.2015.01.022. PMID: 25634530
Understanding and using sensitivity, specificity and predictive values.
Parikh R, Mathai A, Parikh S, Chandra Sekhar G, Thomas R
Indian J Ophthalmol 2008 Jan-Feb;56(1):45-50. doi: 10.4103/0301-4738.37595. PMID: 18158403Free PMC Article
Criteria for diagnosis of Behçet's disease. International Study Group for Behçet's Disease.
Lancet 1990 May 5;335(8697):1078-80. PMID: 1970380

Recent systematic reviews

Interventions for the Management of Computer Vision Syndrome: A Systematic Review and Meta-analysis.
Singh S, McGuinness MB, Anderson AJ, Downie LE
Ophthalmology 2022 Oct;129(10):1192-1215. Epub 2022 May 18 doi: 10.1016/j.ophtha.2022.05.009. PMID: 35597519
Vitamin D and Ocular Diseases: A Systematic Review.
Chan HN, Zhang XJ, Ling XT, Bui CH, Wang YM, Ip P, Chu WK, Chen LJ, Tham CC, Yam JC, Pang CP
Int J Mol Sci 2022 Apr 11;23(8) doi: 10.3390/ijms23084226. PMID: 35457041Free PMC Article
Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study.
GBD 2019 Blindness and Vision Impairment Collaborators; Vision Loss Expert Group of the Global Burden of Disease Study
Lancet Glob Health 2021 Feb;9(2):e144-e160. Epub 2020 Dec 1 doi: 10.1016/S2214-109X(20)30489-7. PMID: 33275949Free PMC Article
Global causes of blindness and distance vision impairment 1990-2020: a systematic review and meta-analysis.
Flaxman SR, Bourne RRA, Resnikoff S, Ackland P, Braithwaite T, Cicinelli MV, Das A, Jonas JB, Keeffe J, Kempen JH, Leasher J, Limburg H, Naidoo K, Pesudovs K, Silvester A, Stevens GA, Tahhan N, Wong TY, Taylor HR; Vision Loss Expert Group of the Global Burden of Disease Study
Lancet Glob Health 2017 Dec;5(12):e1221-e1234. Epub 2017 Oct 11 doi: 10.1016/S2214-109X(17)30393-5. PMID: 29032195
Conjunctivitis: a systematic review of diagnosis and treatment.
Azari AA, Barney NP
JAMA 2013 Oct 23;310(16):1721-9. doi: 10.1001/jama.2013.280318. PMID: 24150468Free PMC Article

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