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Central retinal vein occlusion

MedGen UID:
509679
•Concept ID:
C0154841
•
Disease or Syndrome
Synonym: Central Retinal Vein Occlusion
SNOMED CT: Central retinal vein occlusion (68478007); CRVT - Central retinal vein thrombosis (68478007); CRVO - Central retinal vein occlusion (68478007); Central retinal vein thrombosis (68478007)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Not genetically inherited (Orphanet)
 
HPO: HP:0020166
Monarch Initiative: MONDO:0002303
Orphanet: ORPHA411527

Definition

Central retinal vein occlusion is an occlusion of the main retinal vein posterior to the lamina cribrosa of the optic nerve and is typically caused by thrombosis. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral retinal vein occlusion

Professional guidelines

PubMed

A review of neovascular glaucoma. Etiopathogenesis and treatment.
Dumbrăveanu L, Cușnir V, Bobescu D
Rom J Ophthalmol 2021 Oct-Dec;65(4):315-329. doi: 10.22336/rjo.2021.66. PMID: 35087972Free PMC Article
Central retinal vein occlusion: modifying current treatment protocols.
Ashraf M, Souka AA, Singh RP
Eye (Lond) 2016 Apr;30(4):505-14. Epub 2016 Feb 12 doi: 10.1038/eye.2016.10. PMID: 26869163Free PMC Article
Retinal vein thrombosis: pathogenesis and management.
Rehak M, Wiedemann P
J Thromb Haemost 2010 Sep;8(9):1886-94. doi: 10.1111/j.1538-7836.2010.03909.x. PMID: 20492457

Recent clinical studies

Etiology

Central Retinal Vein Occlusion after COVID-19 Infection.
Nguyen NI, Eandi C, Guex-Crosier Y
Klin Monbl Augenheilkd 2023 Apr;240(4):509-513. Epub 2023 Apr 25 doi: 10.1055/a-2040-3653. PMID: 37164394
Clinical implications of retinal oximetry in retinal vein occlusion: a review.
Belamkar AV, Jabbehdari S, Harris A, Hajrasouliha AR
Acta Ophthalmol 2022 Sep;100(6):624-631. Epub 2021 Nov 29 doi: 10.1111/aos.15066. PMID: 34845846Free PMC Article
Photocoagulation for retinal vein occlusion.
Hayreh SS
Prog Retin Eye Res 2021 Nov;85:100964. Epub 2021 Mar 11 doi: 10.1016/j.preteyeres.2021.100964. PMID: 33713810
Central retinal vein occlusion: a review.
McAllister IL
Clin Exp Ophthalmol 2012 Jan-Feb;40(1):48-58. Epub 2011 Dec 6 doi: 10.1111/j.1442-9071.2011.02713.x. PMID: 22003973
Branch retinal vein occlusion.
Hamid S, Mirza SA, Shokh I
J Ayub Med Coll Abbottabad 2008 Apr-Jun;20(2):128-32. PMID: 19385476

Diagnosis

Peripapillary fluid: Obvious and not so obvious!
Arora S, Zur D, Iovino C, Chhablani J
Surv Ophthalmol 2024 May-Jun;69(3):311-329. Epub 2023 Nov 26 doi: 10.1016/j.survophthal.2023.11.004. PMID: 38016521
Central Retinal Vein Occlusion after COVID-19 Infection.
Nguyen NI, Eandi C, Guex-Crosier Y
Klin Monbl Augenheilkd 2023 Apr;240(4):509-513. Epub 2023 Apr 25 doi: 10.1055/a-2040-3653. PMID: 37164394
Endovascular surgery in the field of ophthalmology.
Kadonosono K, Hayashi A, de Juan E Jr
Jpn J Ophthalmol 2021 Jan;65(1):1-5. Epub 2020 Nov 8 doi: 10.1007/s10384-020-00776-7. PMID: 33161486
Branch retinal vein occlusion.
Hamid S, Mirza SA, Shokh I
J Ayub Med Coll Abbottabad 2008 Apr-Jun;20(2):128-32. PMID: 19385476
Acute visual change.
Morgan A, Hemphill RR
Emerg Med Clin North Am 1998 Nov;16(4):825-43, vii. doi: 10.1016/s0733-8627(05)70035-3. PMID: 9889742

Therapy

Retinal arterial and vein occlusion: is surgery ever indicated?
Kadonosono K, Inoue M, Yanagi Y
Curr Opin Ophthalmol 2024 May 1;35(3):210-216. Epub 2024 Feb 28 doi: 10.1097/ICU.0000000000001045. PMID: 38421954
Use of erythropoietin in ophthalmology: a review.
Feizi S, Alemzadeh-Ansari M, Karimian F, Esfandiari H
Surv Ophthalmol 2022 Mar-Apr;67(2):427-439. Epub 2021 Jun 23 doi: 10.1016/j.survophthal.2021.06.002. PMID: 34157346
Photocoagulation for retinal vein occlusion.
Hayreh SS
Prog Retin Eye Res 2021 Nov;85:100964. Epub 2021 Mar 11 doi: 10.1016/j.preteyeres.2021.100964. PMID: 33713810
Central retinal vein occlusion: modifying current treatment protocols.
Ashraf M, Souka AA, Singh RP
Eye (Lond) 2016 Apr;30(4):505-14. Epub 2016 Feb 12 doi: 10.1038/eye.2016.10. PMID: 26869163Free PMC Article
Retinal vein thrombosis: pathogenesis and management.
Rehak M, Wiedemann P
J Thromb Haemost 2010 Sep;8(9):1886-94. doi: 10.1111/j.1538-7836.2010.03909.x. PMID: 20492457

Prognosis

Mechanisms of macular edema: Beyond the surface.
Daruich A, Matet A, Moulin A, Kowalczuk L, Nicolas M, Sellam A, Rothschild PR, Omri S, Gélizé E, Jonet L, Delaunay K, De Kozak Y, Berdugo M, Zhao M, Crisanti P, Behar-Cohen F
Prog Retin Eye Res 2018 Mar;63:20-68. Epub 2017 Nov 7 doi: 10.1016/j.preteyeres.2017.10.006. PMID: 29126927
Central retinal vein occlusion: modifying current treatment protocols.
Ashraf M, Souka AA, Singh RP
Eye (Lond) 2016 Apr;30(4):505-14. Epub 2016 Feb 12 doi: 10.1038/eye.2016.10. PMID: 26869163Free PMC Article
Cilioretinal artery occlusion.
Stoffelns BM, Laspas P
Klin Monbl Augenheilkd 2015 Apr;232(4):519-24. Epub 2015 Apr 22 doi: 10.1055/s-0034-1396327. PMID: 25902112
Branch retinal vein occlusion.
Hamid S, Mirza SA, Shokh I
J Ayub Med Coll Abbottabad 2008 Apr-Jun;20(2):128-32. PMID: 19385476
Retinal vein occlusion.
Hayreh SS
Indian J Ophthalmol 1994 Sep;42(3):109-32. PMID: 7829175

Clinical prediction guides

Retinal Manifestations in High Altitude.
Dangi M, Sadhukhan A, Kumar P, Bandopadhyay S, Sharma VK, Patra VK, Chaudhary M, Rana V
High Alt Med Biol 2023 Dec;24(4):296-301. Epub 2023 Aug 1 doi: 10.1089/ham.2023.0051. PMID: 37527184
Central Retinal Vein Occlusion after COVID-19 Infection.
Nguyen NI, Eandi C, Guex-Crosier Y
Klin Monbl Augenheilkd 2023 Apr;240(4):509-513. Epub 2023 Apr 25 doi: 10.1055/a-2040-3653. PMID: 37164394
Association of glaucoma with risk of retinal vein occlusion: A meta-analysis.
Yin X, Li J, Zhang B, Lu P
Acta Ophthalmol 2019 Nov;97(7):652-659. Epub 2019 May 24 doi: 10.1111/aos.14141. PMID: 31125174
Ocular manifestations of pulmonary hypertension.
Lewczuk N, Zdebik A, Bogusławska J, Turno-Kręcicka A, Misiuk-Hojło M
Surv Ophthalmol 2019 Sep-Oct;64(5):694-699. Epub 2019 Mar 6 doi: 10.1016/j.survophthal.2019.02.009. PMID: 30849428
Central retinal vein occlusion: modifying current treatment protocols.
Ashraf M, Souka AA, Singh RP
Eye (Lond) 2016 Apr;30(4):505-14. Epub 2016 Feb 12 doi: 10.1038/eye.2016.10. PMID: 26869163Free PMC Article

Recent systematic reviews

Retinal oximetry in patients with ischaemic retinal diseases.
Rilvén S, Torp TL, Grauslund J
Acta Ophthalmol 2017 Mar;95(2):119-127. Epub 2016 Sep 1 doi: 10.1111/aos.13229. PMID: 27585711
Treatments for macular oedema following central retinal vein occlusion: systematic review.
Ford JA, Clar C, Lois N, Barton S, Thomas S, Court R, Shyangdan D, Waugh N
BMJ Open 2014 Feb 10;4(2):e004120. doi: 10.1136/bmjopen-2013-004120. PMID: 24513867Free PMC Article
Ocular ischemic syndrome - a systematic review.
Terelak-Borys B, Skonieczna K, Grabska-Liberek I
Med Sci Monit 2012 Aug;18(8):RA138-144. doi: 10.12659/msm.883260. PMID: 22847215Free PMC Article
Natural history of central retinal vein occlusion: an evidence-based systematic review.
McIntosh RL, Rogers SL, Lim L, Cheung N, Wang JJ, Mitchell P, Kowalski JW, Nguyen HP, Wong TY
Ophthalmology 2010 Jun;117(6):1113-1123.e15. doi: 10.1016/j.ophtha.2010.01.060. PMID: 20430446
Interventions for central retinal vein occlusion: an evidence-based systematic review.
Mohamed Q, McIntosh RL, Saw SM, Wong TY
Ophthalmology 2007 Mar;114(3):507-19, 524. doi: 10.1016/j.ophtha.2006.11.011. PMID: 17324695

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