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Vulval varicose vein

MedGen UID:
510083
•Concept ID:
C0155796
•
Disease or Syndrome
Synonyms: mammalian vulva varicose disease; varicose disease of mammalian vulva; Varicose veins of vulva; Vulval varices; vulval varices
SNOMED CT: Varicose veins of vulva (48868008); Vulval varices (48868008)
 
HPO: HP:0100677
Monarch Initiative: MONDO:0021642

Definition

Varicosity of veins in the vulval region. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVulval varicose vein

Professional guidelines

PubMed

Research Priorities in Pelvic Venous Disorders in Women: Recommendations from a Multidisciplinary Research Consensus Panel.
Khilnani NM, Meissner MH, Learman LA, Gibson KD, Daniels JP, Winokur RS, Marvel RP, Machan L, Venbrux AC, Tu FF, Pabon-Ramos WM, Nedza SM, White SB, Rosenblatt M
J Vasc Interv Radiol 2019 Jun;30(6):781-789. Epub 2019 Mar 8 doi: 10.1016/j.jvir.2018.10.008. PMID: 30857986
Pelvic congestion syndrome: the role of interventional radiology in the treatment of chronic pelvic pain.
Freedman J, Ganeshan A, Crowe PM
Postgrad Med J 2010 Dec;86(1022):704-10. doi: 10.1136/pgmj.2010.099473. PMID: 21106807
Klippel-Trenaunay syndrome: clinical features, complications and management in children.
Samuel M, Spitz L
Br J Surg 1995 Jun;82(6):757-61. doi: 10.1002/bjs.1800820615. PMID: 7542989

Recent clinical studies

Etiology

Clinical Presentation and Evaluation of Pelvic Venous Disorders in Women.
Khilnani NM, Winokur RS, Scherer KL, Meissner MH
Tech Vasc Interv Radiol 2021 Mar;24(1):100730. Epub 2021 Apr 16 doi: 10.1016/j.tvir.2021.100730. PMID: 34147196
Does pelvic congestion syndrome influence symptoms of chronic venous disease of the lower extremities?
Gavrilov SG, Moskalenko YP
Eur J Obstet Gynecol Reprod Biol 2019 Dec;243:83-86. Epub 2019 Oct 22 doi: 10.1016/j.ejogrb.2019.10.025. PMID: 31675634
Vulvar Varicosities: A Review.
Kim AS, Greyling LA, Davis LS
Dermatol Surg 2017 Mar;43(3):351-356. doi: 10.1097/DSS.0000000000001008. PMID: 28005626
Pattern and types of non-saphenous vein reflux.
Malgor RD, Labropoulos N
Phlebology 2013 Mar;28 Suppl 1:51-4. doi: 10.1177/0268355513476637. PMID: 23482535
Embolization to treat pelvic congestion syndrome and vulval varicose veins.
van der Vleuten CJ, van Kempen JA, Schultze-Kool LJ
Int J Gynaecol Obstet 2012 Sep;118(3):227-30. Epub 2012 Jun 22 doi: 10.1016/j.ijgo.2012.04.021. PMID: 22727416

Diagnosis

Clinical Presentation and Evaluation of Pelvic Venous Disorders in Women.
Khilnani NM, Winokur RS, Scherer KL, Meissner MH
Tech Vasc Interv Radiol 2021 Mar;24(1):100730. Epub 2021 Apr 16 doi: 10.1016/j.tvir.2021.100730. PMID: 34147196
Pattern and types of non-saphenous vein reflux.
Malgor RD, Labropoulos N
Phlebology 2013 Mar;28 Suppl 1:51-4. doi: 10.1177/0268355513476637. PMID: 23482535
Varicose veins arising from the pelvis due to ovarian vein incompetence.
Hobbs JT
Int J Clin Pract 2005 Oct;59(10):1195-203. doi: 10.1111/j.1368-5031.2005.00631.x. PMID: 16178988
Bockenheimer's syndrome.
van Geest AJ, Veraart JC, de Haan M, Neumann HA
J Eur Acad Dermatol Venereol 1999 Mar;12(2):165-8. PMID: 10343948
Venous dynamics--varicosities.
Sumner DS
Clin Obstet Gynecol 1981 Sep;24(3):743-60. doi: 10.1097/00003081-198109000-00004. PMID: 7026103

Therapy

CT venography combined with ultrasound-guided minimally invasive treatment for recurrent varicose veins: a pilot paired-design clinical trial.
Huang Y, Li X, Niu L, Zhang H, Zhang C, Feng Y, Wang Z, Zhang F, Luo X
Clin Radiol 2024 May;79(5):363-370. Epub 2024 Jan 19 doi: 10.1016/j.crad.2023.12.023. PMID: 38290939
The predictive value of common symptoms in early pregnancy for complications later in pregnancy and at birth.
Ertmann RK, Nicolaisdottir DR, Kragstrup J, Overbeck G, Kriegbaum M, Siersma V
Acta Obstet Gynecol Scand 2023 Jan;102(1):33-42. Epub 2022 Oct 27 doi: 10.1111/aogs.14474. PMID: 36300886Free PMC Article
Safety and effectiveness of percutaneous sclerotherapy for venous disorders of the labia majora in patients with vascular malformations.
Brill R, Deistung A, Gussew A, Goldann C, Stangl F, Uller W, Rosendahl J, Wildgruber M, Wohlgemuth WA
J Vasc Surg Venous Lymphat Disord 2020 Nov;8(6):1083-1089. Epub 2020 Mar 19 doi: 10.1016/j.jvsv.2020.01.008. PMID: 32199800
Clinical results after coil embolization of the ovarian vein in patients with primary and recurrent lower-limb varices with respect to vulval varices.
Castenmiller PH, de Leur K, de Jong TE, van der Laan L
Phlebology 2013 Aug;28(5):234-8. Epub 2013 May 6 doi: 10.1258/phleb.2012.011117. PMID: 22442360
Estrogen replacement in the menopause.
Utian WH
Obstet Gynecol Annu 1979;8:369-91. PMID: 390456

Prognosis

Clinical Presentation and Evaluation of Pelvic Venous Disorders in Women.
Khilnani NM, Winokur RS, Scherer KL, Meissner MH
Tech Vasc Interv Radiol 2021 Mar;24(1):100730. Epub 2021 Apr 16 doi: 10.1016/j.tvir.2021.100730. PMID: 34147196
Research Priorities in Pelvic Venous Disorders in Women: Recommendations from a Multidisciplinary Research Consensus Panel.
Khilnani NM, Meissner MH, Learman LA, Gibson KD, Daniels JP, Winokur RS, Marvel RP, Machan L, Venbrux AC, Tu FF, Pabon-Ramos WM, Nedza SM, White SB, Rosenblatt M
J Vasc Interv Radiol 2019 Jun;30(6):781-789. Epub 2019 Mar 8 doi: 10.1016/j.jvir.2018.10.008. PMID: 30857986
Vulvar Varicosities: A Review.
Kim AS, Greyling LA, Davis LS
Dermatol Surg 2017 Mar;43(3):351-356. doi: 10.1097/DSS.0000000000001008. PMID: 28005626
The effect of a subsequent pregnancy after transjugular coil embolisation for pelvic vein reflux.
Dos Santos SJ, Holdstock JM, Harrison CC, Whiteley MS
Phlebology 2017 Feb;32(1):27-33. Epub 2016 Jul 9 doi: 10.1177/0268355515623898. PMID: 26769721
Pattern and types of non-saphenous vein reflux.
Malgor RD, Labropoulos N
Phlebology 2013 Mar;28 Suppl 1:51-4. doi: 10.1177/0268355513476637. PMID: 23482535

Clinical prediction guides

The predictive value of common symptoms in early pregnancy for complications later in pregnancy and at birth.
Ertmann RK, Nicolaisdottir DR, Kragstrup J, Overbeck G, Kriegbaum M, Siersma V
Acta Obstet Gynecol Scand 2023 Jan;102(1):33-42. Epub 2022 Oct 27 doi: 10.1111/aogs.14474. PMID: 36300886Free PMC Article
Research Priorities in Pelvic Venous Disorders in Women: Recommendations from a Multidisciplinary Research Consensus Panel.
Khilnani NM, Meissner MH, Learman LA, Gibson KD, Daniels JP, Winokur RS, Marvel RP, Machan L, Venbrux AC, Tu FF, Pabon-Ramos WM, Nedza SM, White SB, Rosenblatt M
J Vasc Interv Radiol 2019 Jun;30(6):781-789. Epub 2019 Mar 8 doi: 10.1016/j.jvir.2018.10.008. PMID: 30857986
Sensitivity and specificity of clinical findings for the diagnosis of pelvic congestion syndrome in women with chronic pelvic pain.
Herrera-Betancourt AL, Villegas-Echeverri JD, López-Jaramillo JD, López-Isanoa JD, Estrada-Alvarez JM
Phlebology 2018 Jun;33(5):303-308. Epub 2017 Apr 5 doi: 10.1177/0268355517702057. PMID: 28379058
Pattern and types of non-saphenous vein reflux.
Malgor RD, Labropoulos N
Phlebology 2013 Mar;28 Suppl 1:51-4. doi: 10.1177/0268355513476637. PMID: 23482535
Klippel-Trenaunay syndrome: clinical features, complications and management in children.
Samuel M, Spitz L
Br J Surg 1995 Jun;82(6):757-61. doi: 10.1002/bjs.1800820615. PMID: 7542989

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