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Staphylococcal scalded skin syndrome

MedGen UID:
52484
Concept ID:
C0038165
Disease or Syndrome
Synonyms: Disease, Ritter; Disease, Ritter's; Ritter Disease; Ritter's Disease; Ritters Disease; Scalded Skin Syndrome, Staphylococcal; Scalded-Skin Syndrome, Staphylococcal; Scalded-Skin Syndromes, Staphylococcal; Staphylococcal Scalded Skin Syndrome; Staphylococcal Scalded-Skin Syndrome; Staphylococcal Scalded-Skin Syndromes; Syndrome, Staphylococcal Scalded-Skin; Syndromes, Staphylococcal Scalded-Skin
SNOMED CT: Staphylococcal scalded skin syndrome (200946001); Scalded skin syndrome (200946001); SSSS - Staphylococcal scalded skin syndrome (200946001)
 
Monarch Initiative: MONDO:0018181
Orphanet: ORPHA36236

Definition

A rare staphylococcal toxemia caused by epidermolytic toxins of <i>Staphylococcus aureus</i> and characterized by the appearance of widespread erythematous patches, on which large blisters develop. Upon rupture of these blisters, the skin appears reddish and scalded. The lesions typically begin in the face and rapidly expand to other parts of the body. The disease may be complicated by pneumonia and sepsis. It most commonly affects newborns and infants. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStaphylococcal scalded skin syndrome
Follow this link to review classifications for Staphylococcal scalded skin syndrome in Orphanet.

Professional guidelines

PubMed

Gray L, Olson J, Brintz BJ, Cipriano SD
Pediatr Dermatol 2022 Nov;39(6):908-913. Epub 2022 Aug 16 doi: 10.1111/pde.15102. PMID: 36440996
Leung AKC, Barankin B, Leong KF
World J Pediatr 2018 Apr;14(2):116-120. Epub 2018 Mar 5 doi: 10.1007/s12519-018-0150-x. PMID: 29508362
Handler MZ, Schwartz RA
J Eur Acad Dermatol Venereol 2014 Nov;28(11):1418-23. Epub 2014 May 20 doi: 10.1111/jdv.12541. PMID: 24841497

Recent clinical studies

Therapy

Garg VK, Buttar HS, Bhat SA, Ainur N, Priya T, Kashyap D, Tuli HS
Recent Adv Inflamm Allergy Drug Discov 2023;17(2):110-120. doi: 10.2174/2772270817666230821102441. PMID: 37605396
Leung AKC, Barankin B, Leong KF
World J Pediatr 2018 Apr;14(2):116-120. Epub 2018 Mar 5 doi: 10.1007/s12519-018-0150-x. PMID: 29508362
Franco L, Pereira P
Indian Pediatr 2016 Oct 8;53(10):939. doi: 10.1007/s13312-016-0966-1. PMID: 27771692
Handler MZ, Schwartz RA
J Eur Acad Dermatol Venereol 2014 Nov;28(11):1418-23. Epub 2014 May 20 doi: 10.1111/jdv.12541. PMID: 24841497
Kress DW
Curr Opin Pediatr 2011 Aug;23(4):403-6. doi: 10.1097/MOP.0b013e3283483efd. PMID: 21670682

Prognosis

Garg VK, Buttar HS, Bhat SA, Ainur N, Priya T, Kashyap D, Tuli HS
Recent Adv Inflamm Allergy Drug Discov 2023;17(2):110-120. doi: 10.2174/2772270817666230821102441. PMID: 37605396
Leung AKC, Barankin B, Leong KF
World J Pediatr 2018 Apr;14(2):116-120. Epub 2018 Mar 5 doi: 10.1007/s12519-018-0150-x. PMID: 29508362
Handler MZ, Schwartz RA
J Eur Acad Dermatol Venereol 2014 Nov;28(11):1418-23. Epub 2014 May 20 doi: 10.1111/jdv.12541. PMID: 24841497
Todd JK
Pediatr Rev 2005 Dec;26(12):444-50. PMID: 16327025
Farrell AM
Lancet 1999 Sep 11;354(9182):880-1. doi: 10.1016/s0140-6736(99)90120-4. PMID: 10489941

Clinical prediction guides

Garg VK, Buttar HS, Bhat SA, Ainur N, Priya T, Kashyap D, Tuli HS
Recent Adv Inflamm Allergy Drug Discov 2023;17(2):110-120. doi: 10.2174/2772270817666230821102441. PMID: 37605396
Liy-Wong C, Pope E, Weinstein M, Lara-Corrales I
Pediatr Dermatol 2021 Jan;38(1):149-153. Epub 2020 Dec 1 doi: 10.1111/pde.14470. PMID: 33283348
Hultén KG, Kok M, King KE, Lamberth LB, Kaplan SL
Pediatr Infect Dis J 2020 Jan;39(1):30-34. doi: 10.1097/INF.0000000000002499. PMID: 31725120
Prévost G, Couppié P, Monteil H
Curr Opin Infect Dis 2003 Apr;16(2):71-6. doi: 10.1097/00001432-200304000-00002. PMID: 12734438
Thestrup-Pedersen K
Br J Dermatol 1998 Dec;139 Suppl 53:1-3. doi: 10.1046/j.1365-2133.1998.1390s3001.x. PMID: 9990405

Supplemental Content

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