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Substance Abuse, Intravenous

MedGen UID:
52537
•Concept ID:
C0038579
•
Mental or Behavioral Dysfunction
Synonym: Intravenous Substance Abuse

Definition

Abuse, overuse, or misuse of a substance by its injection into a vein. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubstance Abuse, Intravenous

Professional guidelines

PubMed

Management of Infective Endocarditis in People Who Inject Drugs: A Scientific Statement From the American Heart Association.
Baddour LM, Weimer MB, Wurcel AG, McElhinney DB, Marks LR, Fanucchi LC, Esquer Garrigos Z, Pettersson GB, DeSimone DC; American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee of the Council on Lifelong Congenital Heart Disease and Heart Health in the Young; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; and Council on Peripheral Vascular Disease
Circulation 2022 Oct 4;146(14):e187-e201. Epub 2022 Aug 31 doi: 10.1161/CIR.0000000000001090. PMID: 36043414
Review of management priorities for invasive infections in people who inject drugs: highlighting the need for patient-centred multidisciplinary care.
Attwood LO, McKechnie M, Vujovic O, Higgs P, Lloyd-Jones M, Doyle JS, Stewardson AJ
Med J Aust 2022 Jul 18;217(2):102-109. Epub 2022 Jun 26 doi: 10.5694/mja2.51623. PMID: 35754144Free PMC Article
Challenges Facing a Rural Opioid Epidemic: Treatment and Prevention of HIV and Hepatitis C.
Schranz AJ, Barrett J, Hurt CB, Malvestutto C, Miller WC
Curr HIV/AIDS Rep 2018 Jun;15(3):245-254. doi: 10.1007/s11904-018-0393-0. PMID: 29796965Free PMC Article

Recent clinical studies

Etiology

Review of management priorities for invasive infections in people who inject drugs: highlighting the need for patient-centred multidisciplinary care.
Attwood LO, McKechnie M, Vujovic O, Higgs P, Lloyd-Jones M, Doyle JS, Stewardson AJ
Med J Aust 2022 Jul 18;217(2):102-109. Epub 2022 Jun 26 doi: 10.5694/mja2.51623. PMID: 35754144Free PMC Article
Psychiatric comorbidity in injecting drug users in Asia and Africa.
Iskandar S, Kamal R, De Jong CA
Curr Opin Psychiatry 2012 May;25(3):213-8. doi: 10.1097/YCO.0b013e3283523d66. PMID: 22449767
Overview of substance abuse and hepatitis C virus infection and co-infections in India.
Basu D
J Neuroimmune Pharmacol 2010 Dec;5(4):496-506. Epub 2010 Jun 19 doi: 10.1007/s11481-010-9227-6. PMID: 20559752
Alcohol and polysubstance abuse among women.
el-Guebaly N
Can J Psychiatry 1995 Mar;40(2):73-9. doi: 10.1177/070674379504000204. PMID: 7788621
Opiate treatments.
Johns A
Addiction 1994 Nov;89(11):1551-8. doi: 10.1111/j.1360-0443.1994.tb03757.x. PMID: 7841870

Diagnosis

Hepatitis C Virus Diagnosis and the Holy Grail.
Applegate TL, Fajardo E, Sacks JA
Infect Dis Clin North Am 2018 Jun;32(2):425-445. doi: 10.1016/j.idc.2018.02.010. PMID: 29778264
Supervised injection services: what has been demonstrated? A systematic literature review.
Potier C, Laprévote V, Dubois-Arber F, Cottencin O, Rolland B
Drug Alcohol Depend 2014 Dec 1;145:48-68. Epub 2014 Oct 23 doi: 10.1016/j.drugalcdep.2014.10.012. PMID: 25456324
Infective endocarditis.
Starakis I
Infect Disord Drug Targets 2010 Feb;10(1):21. doi: 10.2174/187152610790410864. PMID: 20218948
"String-of-pearls".
Lo JS, Lo JO, Hunter AJ
J Hosp Med 2008 May;3(3):272-3. doi: 10.1002/jhm.305. PMID: 18571810
Developing a plan of care using the Roper, Logan and Tierney model.
Mooney M, O'Brien F
Br J Nurs 2006 Sep 14-27;15(16):887-92. doi: 10.12968/bjon.2006.15.16.21854. PMID: 17108861

Therapy

Patient-centred models of hepatitis C treatment for people who inject drugs: a multicentre, pragmatic randomised trial.
Litwin AH, Lum PJ, Taylor LE, Mehta SH, Tsui JI, Feinberg J, Kim AY, Norton BL, Heo M, Arnsten J, Meissner P, Karasz A, Mckee MD, Ward JW, Johnson N, Pericot-Valverde I, Agyemang L, Stein ES, Thomas A, Borsuk C, Blalock KL, Wilkinson S, Wagner K, Roche J, Murray-Krezan C, Anderson J, Jacobsohn V, Luetkemeyer AF, Falade-Nwulia O, Page K; HERO Study Group
Lancet Gastroenterol Hepatol 2022 Dec;7(12):1112-1127. doi: 10.1016/S2468-1253(22)00275-8. PMID: 36370741
Propofol abuse in professionals.
Lee J
J Korean Med Sci 2012 Dec;27(12):1451-2. Epub 2012 Dec 7 doi: 10.3346/jkms.2012.27.12.1451. PMID: 23255841Free PMC Article
Antimicrobials for right-sided endocarditis in intravenous drug users: a systematic review.
Yung D, Kottachchi D, Neupane B, Haider S, Loeb M
J Antimicrob Chemother 2007 Nov;60(5):921-8. Epub 2007 Sep 19 doi: 10.1093/jac/dkm324. PMID: 17881630
Pharmacological and clinical evidences on the potential for abuse and dependence of propofol: a review of the literature.
Roussin A, Montastruc JL, Lapeyre-Mestre M
Fundam Clin Pharmacol 2007 Oct;21(5):459-66. doi: 10.1111/j.1472-8206.2007.00497.x. PMID: 17868199
Injecting drugs of abuse and immunity: implications for HIV vaccine testing and efficacy.
Ugen KE, Nyland SB
Springer Semin Immunopathol 2006 Nov;28(3):281-7. Epub 2006 Oct 13 doi: 10.1007/s00281-006-0045-0. PMID: 17109182

Prognosis

Hearing From the Silent Epidemic.
DeMaria A Jr
Ann Intern Med 2017 Jun 6;166(11):846-847. Epub 2017 May 9 doi: 10.7326/M17-0927. PMID: 28492930
Endocarditis.
Farmer JA, Torre G
Curr Opin Cardiol 1997 Mar;12(2):123-30. doi: 10.1097/00001573-199703000-00006. PMID: 9192480
Necrotizing soft-tissue infections.
Bosshardt TL, Henderson VJ, Organ CH Jr
Arch Surg 1996 Aug;131(8):846-52; discussion 852-4. doi: 10.1001/archsurg.1996.01430200056011. PMID: 8712909
Alcohol and drug abuse in Nepal.
Shrestha NM
Br J Addict 1992 Sep;87(9):1241-8. doi: 10.1111/j.1360-0443.1992.tb02733.x. PMID: 1392549
Compulsory treatment for drug abuse.
Leukefeld CG, Tims FM
Int J Addict 1990 Jun;25(6):621-40. doi: 10.3109/10826089009061324. PMID: 2265866

Clinical prediction guides

Baseline parameters and the prediction of treatment failure in patients with intravenous drug use-associated spinal epidural abscesses.
Baum J, Viljoen SV, Gifford CS, Minnema AJ, Shaikhouni A, Grossbach AJ, Nimjee S, Farhadi HF
J Neurosurg Spine 2022 Apr 1;36(4):660-669. Epub 2021 Nov 5 doi: 10.3171/2021.7.SPINE21689. PMID: 34740181
Impact of clinical and sociodemographic factors on fatigue among patients with substance use disorder: a cohort study from Norway for the period 2016-2020.
Vold JH, Gjestad R, Aas CF, Chalabianloo F, Skurtveit S, Løberg EM, Johansson KA, Fadnes LT; INTRO-HCV Study Group
Subst Abuse Treat Prev Policy 2020 Dec 14;15(1):93. doi: 10.1186/s13011-020-00334-x. PMID: 33317568Free PMC Article
Rehabilitation Outcomes in Spinal Abscess Patients With and Without a History of Intravenous Substance Abuse.
Raut N, Nagar VR, Springer JE, Sawaki L, Salles SS
Am J Phys Med Rehabil 2018 Jun;97(6):397-400. doi: 10.1097/PHM.0000000000000865. PMID: 29189305
Childhood Adversities and Substance Misuse Among the Incarcerated: Implications for Treatment and Practice in Correctional Settings.
Marotta PL
Subst Use Misuse 2017 May 12;52(6):717-733. Epub 2017 Feb 7 doi: 10.1080/10826084.2016.1261899. PMID: 28379110Free PMC Article
Meta-analysis of depression and substance use and impairment among intravenous drug users (IDUs).
Conner KR, Pinquart M, Duberstein PR
Addiction 2008 Apr;103(4):524-34. Epub 2008 Feb 4 doi: 10.1111/j.1360-0443.2007.02118.x. PMID: 18261192Free PMC Article

Recent systematic reviews

Supervised Injection Facilities as Harm Reduction: A Systematic Review.
Levengood TW, Yoon GH, Davoust MJ, Ogden SN, Marshall BDL, Cahill SR, Bazzi AR
Am J Prev Med 2021 Nov;61(5):738-749. Epub 2021 Jul 1 doi: 10.1016/j.amepre.2021.04.017. PMID: 34218964Free PMC Article
The global prevalence of hepatitis D virus infection: Systematic review and meta-analysis.
Stockdale AJ, Kreuels B, Henrion MYR, Giorgi E, Kyomuhangi I, de Martel C, Hutin Y, Geretti AM
J Hepatol 2020 Sep;73(3):523-532. Epub 2020 Apr 23 doi: 10.1016/j.jhep.2020.04.008. PMID: 32335166Free PMC Article
Low Back Pain in the Emergency Department: Prevalence of Serious Spinal Pathologies and Diagnostic Accuracy of Red Flags.
Galliker G, Scherer DE, Trippolini MA, Rasmussen-Barr E, LoMartire R, Wertli MM
Am J Med 2020 Jan;133(1):60-72.e14. Epub 2019 Jul 3 doi: 10.1016/j.amjmed.2019.06.005. PMID: 31278933
Global prevalence of injecting drug use and sociodemographic characteristics and prevalence of HIV, HBV, and HCV in people who inject drugs: a multistage systematic review.
Degenhardt L, Peacock A, Colledge S, Leung J, Grebely J, Vickerman P, Stone J, Cunningham EB, Trickey A, Dumchev K, Lynskey M, Griffiths P, Mattick RP, Hickman M, Larney S
Lancet Glob Health 2017 Dec;5(12):e1192-e1207. Epub 2017 Oct 23 doi: 10.1016/S2214-109X(17)30375-3. PMID: 29074409Free PMC Article
Supervised injection services: what has been demonstrated? A systematic literature review.
Potier C, Laprévote V, Dubois-Arber F, Cottencin O, Rolland B
Drug Alcohol Depend 2014 Dec 1;145:48-68. Epub 2014 Oct 23 doi: 10.1016/j.drugalcdep.2014.10.012. PMID: 25456324

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