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Substance Abuse, Intravenous

MedGen UID:
52537
•Concept ID:
C0038579
•
Mental or Behavioral Dysfunction
Synonym: Intravenous Substance Abuse

Definition

Abuse, overuse, or misuse of a substance by its injection into a vein. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubstance Abuse, Intravenous

Professional guidelines

PubMed

Consensus recommendations on the management of hepatitis C in Australia's prisons.
Winter RJ, Sheehan Y, Papaluca T, Macdonald GA, Rowland J, Colman A, Stoove M, Lloyd AR, Thompson AJ
Med J Aust 2023 Mar 20;218(5):231-237. Epub 2023 Mar 5 doi: 10.5694/mja2.51854. PMID: 36871200
Management of Infective Endocarditis in People Who Inject Drugs: A Scientific Statement From the American Heart Association.
Baddour LM, Weimer MB, Wurcel AG, McElhinney DB, Marks LR, Fanucchi LC, Esquer Garrigos Z, Pettersson GB, DeSimone DC; American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee of the Council on Lifelong Congenital Heart Disease and Heart Health in the Young; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; and Council on Peripheral Vascular Disease
Circulation 2022 Oct 4;146(14):e187-e201. Epub 2022 Aug 31 doi: 10.1161/CIR.0000000000001090. PMID: 36043414
Challenges Facing a Rural Opioid Epidemic: Treatment and Prevention of HIV and Hepatitis C.
Schranz AJ, Barrett J, Hurt CB, Malvestutto C, Miller WC
Curr HIV/AIDS Rep 2018 Jun;15(3):245-254. doi: 10.1007/s11904-018-0393-0. PMID: 29796965Free PMC Article

Recent clinical studies

Etiology

Novel Circovirus in Blood from Intravenous Drug Users, Yunnan, China.
Li Y, Zhang P, Ye M, Tian RR, Li N, Cao L, Ma Y, Liu FL, Zheng YT, Zhang C
Emerg Infect Dis 2023 May;29(5):1015-1019. doi: 10.3201/eid2905.221617. PMID: 37081583Free PMC Article
Review of management priorities for invasive infections in people who inject drugs: highlighting the need for patient-centred multidisciplinary care.
Attwood LO, McKechnie M, Vujovic O, Higgs P, Lloyd-Jones M, Doyle JS, Stewardson AJ
Med J Aust 2022 Jul 18;217(2):102-109. Epub 2022 Jun 26 doi: 10.5694/mja2.51623. PMID: 35754144Free PMC Article
Epidemiology of Injection Drug Use: New Trends and Prominent Issues.
Roy É, Arruda N, Bruneau J, Jutras-Aswad D
Can J Psychiatry 2016 Mar;61(3):136-44. Epub 2016 Feb 10 doi: 10.1177/0706743716632503. PMID: 27254088Free PMC Article
Overview of substance abuse and hepatitis C virus infection and co-infections in India.
Basu D
J Neuroimmune Pharmacol 2010 Dec;5(4):496-506. Epub 2010 Jun 19 doi: 10.1007/s11481-010-9227-6. PMID: 20559752
Opiate treatments.
Johns A
Addiction 1994 Nov;89(11):1551-8. doi: 10.1111/j.1360-0443.1994.tb03757.x. PMID: 7841870

Diagnosis

Serratia marcescens Endocarditis.
Oliver T, Vazquez J
J Investig Med High Impact Case Rep 2023 Jan-Dec;11:23247096231222414. doi: 10.1177/23247096231222414. PMID: 38146713Free PMC Article
Community-acquired skin and soft-tissue infections in people who inject drugs.
Allaw F, Zakhour J, Kanj SS
Curr Opin Infect Dis 2023 Apr 1;36(2):67-73. Epub 2023 Jan 25 doi: 10.1097/QCO.0000000000000902. PMID: 36718912
Supervised injection services: what has been demonstrated? A systematic literature review.
Potier C, Laprévote V, Dubois-Arber F, Cottencin O, Rolland B
Drug Alcohol Depend 2014 Dec 1;145:48-68. Epub 2014 Oct 23 doi: 10.1016/j.drugalcdep.2014.10.012. PMID: 25456324
Infective endocarditis.
Starakis I
Infect Disord Drug Targets 2010 Feb;10(1):21. doi: 10.2174/187152610790410864. PMID: 20218948
Developing a plan of care using the Roper, Logan and Tierney model.
Mooney M, O'Brien F
Br J Nurs 2006 Sep 14-27;15(16):887-92. doi: 10.12968/bjon.2006.15.16.21854. PMID: 17108861

Therapy

Patterns of smoking and injecting methamphetamine and their association with health and social outcomes.
McKetin R, Sutherland R, Peacock A, Farrell M, Degenhardt L
Drug Alcohol Rev 2021 Nov;40(7):1256-1265. Epub 2021 Aug 8 doi: 10.1111/dar.13364. PMID: 34365687Free PMC Article
Abuse liability of intravenous buprenorphine/naloxone and buprenorphine alone in buprenorphine-maintained intravenous heroin abusers.
Comer SD, Sullivan MA, Vosburg SK, Manubay J, Amass L, Cooper ZD, Saccone P, Kleber HD
Addiction 2010 Apr;105(4):709-18. doi: 10.1111/j.1360-0443.2009.02843.x. PMID: 20403021Free PMC Article
Antimicrobials for right-sided endocarditis in intravenous drug users: a systematic review.
Yung D, Kottachchi D, Neupane B, Haider S, Loeb M
J Antimicrob Chemother 2007 Nov;60(5):921-8. Epub 2007 Sep 19 doi: 10.1093/jac/dkm324. PMID: 17881630
Pharmacological and clinical evidences on the potential for abuse and dependence of propofol: a review of the literature.
Roussin A, Montastruc JL, Lapeyre-Mestre M
Fundam Clin Pharmacol 2007 Oct;21(5):459-66. doi: 10.1111/j.1472-8206.2007.00497.x. PMID: 17868199
Injecting drugs of abuse and immunity: implications for HIV vaccine testing and efficacy.
Ugen KE, Nyland SB
Springer Semin Immunopathol 2006 Nov;28(3):281-7. Epub 2006 Oct 13 doi: 10.1007/s00281-006-0045-0. PMID: 17109182

Prognosis

Surgery for Endocarditis in Intravenous Drug Users.
Bearpark L, Sartipy U, Franco-Cereceda A, Glaser N
Ann Thorac Surg 2021 Aug;112(2):573-581. Epub 2020 Oct 27 doi: 10.1016/j.athoracsur.2020.09.013. PMID: 33127400
Self-treatment of skin infections by people who inject drugs.
Monteiro J, Phillips KT, Herman DS, Stewart C, Keosaian J, Anderson BJ, Stein MD
Drug Alcohol Depend 2020 Jan 1;206:107695. Epub 2019 Oct 28 doi: 10.1016/j.drugalcdep.2019.107695. PMID: 31786397
HIV incidence and prevalence among aboriginal peoples in Canada.
Duncan KC, Reading C, Borwein AM, Murray MC, Palmer A, Michelow W, Samji H, Lima VD, Montaner JS, Hogg RS
AIDS Behav 2011 Jan;15(1):214-27. doi: 10.1007/s10461-010-9792-y. PMID: 20799061
Epidemiology of HIV in the United States.
Lansky A, Brooks JT, DiNenno E, Heffelfinger J, Hall HI, Mermin J
J Acquir Immune Defic Syndr 2010 Dec;55 Suppl 2:S64-8. doi: 10.1097/QAI.0b013e3181fbbe15. PMID: 21406989
Alcohol and drug abuse in Nepal.
Shrestha NM
Br J Addict 1992 Sep;87(9):1241-8. doi: 10.1111/j.1360-0443.1992.tb02733.x. PMID: 1392549

Clinical prediction guides

Correlates of Intersectional HIV and Substance Use Stigma Affecting People with HIV and Substance Use in St. Petersburg, Russia.
Lodi S, Rossi SL, Bendiks S, Gnatienko N, Lloyd-Travaglini C, Vetrova M, Toussova O, Bushara N, Blokhina E, Krupitsky E, Ekstrand ML, Lioznov D, Samet JH, Lunze K
AIDS Behav 2023 Feb;27(2):462-472. Epub 2022 Aug 2 doi: 10.1007/s10461-022-03781-8. PMID: 35916947Free PMC Article
Baseline parameters and the prediction of treatment failure in patients with intravenous drug use-associated spinal epidural abscesses.
Baum J, Viljoen SV, Gifford CS, Minnema AJ, Shaikhouni A, Grossbach AJ, Nimjee S, Farhadi HF
J Neurosurg Spine 2022 Apr 1;36(4):660-669. Epub 2021 Nov 5 doi: 10.3171/2021.7.SPINE21689. PMID: 34740181
Rehabilitation Outcomes in Spinal Abscess Patients With and Without a History of Intravenous Substance Abuse.
Raut N, Nagar VR, Springer JE, Sawaki L, Salles SS
Am J Phys Med Rehabil 2018 Jun;97(6):397-400. doi: 10.1097/PHM.0000000000000865. PMID: 29189305
Childhood Adversities and Substance Misuse Among the Incarcerated: Implications for Treatment and Practice in Correctional Settings.
Marotta PL
Subst Use Misuse 2017 May 12;52(6):717-733. Epub 2017 Feb 7 doi: 10.1080/10826084.2016.1261899. PMID: 28379110Free PMC Article
Meta-analysis of depression and substance use and impairment among intravenous drug users (IDUs).
Conner KR, Pinquart M, Duberstein PR
Addiction 2008 Apr;103(4):524-34. Epub 2008 Feb 4 doi: 10.1111/j.1360-0443.2007.02118.x. PMID: 18261192Free PMC Article

Recent systematic reviews

Supervised Injection Facilities as Harm Reduction: A Systematic Review.
Levengood TW, Yoon GH, Davoust MJ, Ogden SN, Marshall BDL, Cahill SR, Bazzi AR
Am J Prev Med 2021 Nov;61(5):738-749. Epub 2021 Jul 1 doi: 10.1016/j.amepre.2021.04.017. PMID: 34218964Free PMC Article
The global prevalence of hepatitis D virus infection: Systematic review and meta-analysis.
Stockdale AJ, Kreuels B, Henrion MYR, Giorgi E, Kyomuhangi I, de Martel C, Hutin Y, Geretti AM
J Hepatol 2020 Sep;73(3):523-532. Epub 2020 Apr 23 doi: 10.1016/j.jhep.2020.04.008. PMID: 32335166Free PMC Article
Global prevalence of injecting drug use and sociodemographic characteristics and prevalence of HIV, HBV, and HCV in people who inject drugs: a multistage systematic review.
Degenhardt L, Peacock A, Colledge S, Leung J, Grebely J, Vickerman P, Stone J, Cunningham EB, Trickey A, Dumchev K, Lynskey M, Griffiths P, Mattick RP, Hickman M, Larney S
Lancet Glob Health 2017 Dec;5(12):e1192-e1207. Epub 2017 Oct 23 doi: 10.1016/S2214-109X(17)30375-3. PMID: 29074409Free PMC Article
Supervised injection services: what has been demonstrated? A systematic literature review.
Potier C, Laprévote V, Dubois-Arber F, Cottencin O, Rolland B
Drug Alcohol Depend 2014 Dec 1;145:48-68. Epub 2014 Oct 23 doi: 10.1016/j.drugalcdep.2014.10.012. PMID: 25456324
Desomorphine goes "crocodile".
Gahr M, Freudenmann RW, Hiemke C, Gunst IM, Connemann BJ, Schönfeldt-Lecuona C
J Addict Dis 2012;31(4):407-12. doi: 10.1080/10550887.2012.735570. PMID: 23244560

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