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Odynophagia

MedGen UID:
526172
•Concept ID:
C0221150
•
Sign or Symptom
Synonyms: Pain on swallowing; Painful swallowing; Swallowing painful
SNOMED CT: Swallowing painful (30233002); Odynophagia (30233002); Painful swallowing (30233002); Pain on swallowing (30233002)
 
HPO: HP:0032043

Definition

Pain experienced with swallowing. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOdynophagia

Professional guidelines

PubMed

Early side effects of radiation treatment for head and neck cancer.
Brook I
Cancer Radiother 2021 Jul;25(5):507-513. Epub 2021 Mar 5 doi: 10.1016/j.canrad.2021.02.001. PMID: 33685809
Recent advances in dysphagia management.
Triggs J, Pandolfino J
F1000Res 2019;8 Epub 2019 Aug 29 doi: 10.12688/f1000research.18900.1. PMID: 31508201Free PMC Article
Nutrition Management for the Head and Neck Cancer Patient.
Ackerman D, Laszlo M, Provisor A, Yu A
Cancer Treat Res 2018;174:187-208. doi: 10.1007/978-3-319-65421-8_11. PMID: 29435843

Recent clinical studies

Etiology

Results of Phase III Randomized Trial for Use of Docetaxel as a Radiosensitizer in Patients With Head and Neck Cancer, Unsuitable for Cisplatin-Based Chemoradiation.
Patil VM, Noronha V, Menon N, Singh A, Ghosh-Laskar S, Budrukkar A, Bhattacharjee A, Swain M, Mathrudev V, Nawale K, Balaji A, Peelay Z, Alone M, Pathak S, Mahajan A, Kumar S, Purandare N, Agarwal A, Puranik A, Pendse S, Reddy Yallala M, Sahu H, Kapu V, Dey S, Choudhary J, Krishna MR, Shetty A, Karuvandan N, Ravind R, Rai R, Jobanputra K, Chaturvedi P, Pai PS, Chaukar D, Nair S, Thiagarajan S, Prabhash K
J Clin Oncol 2023 May 1;41(13):2350-2361. Epub 2023 Jan 27 doi: 10.1200/JCO.22.00980. PMID: 36706347
Monkeypox.
Mitjà O, Ogoina D, Titanji BK, Galvan C, Muyembe JJ, Marks M, Orkin CM
Lancet 2023 Jan 7;401(10370):60-74. Epub 2022 Nov 17 doi: 10.1016/S0140-6736(22)02075-X. PMID: 36403582Free PMC Article
Infectious Esophagitis in Children.
O'Donnell JEM, Krishnan U
J Pediatr Gastroenterol Nutr 2022 Nov 1;75(5):556-563. Epub 2022 Jun 10 doi: 10.1097/MPG.0000000000003523. PMID: 35687591
Acute odynophagia: A new symptom of COVID-19 during the SARS-CoV-2 Omicron variant wave in Sweden.
Piersiala K, Kakabas L, Bruckova A, Starkhammar M, Cardell LO
J Intern Med 2022 Jul;292(1):154-161. Epub 2022 Mar 6 doi: 10.1111/joim.13470. PMID: 35170099Free PMC Article
Acute longus colli tendinitis and otolaryngology.
Siag K, Mazzawi S, Paker M, Biener R, Ghanayim R, Lumelsky D
Braz J Otorhinolaryngol 2022 May-Jun;88(3):351-357. Epub 2020 Dec 5 doi: 10.1016/j.bjorl.2020.10.018. PMID: 33342696Free PMC Article

Diagnosis

Covid-induced thyroiditis.
Ghaffar T, Babar B, Ahmad MS, Rahman A, Zia S, Aamir AH
J Pak Med Assoc 2023 Jan;73(1):177-179. doi: 10.47391/JPMA.4974. PMID: 36842035
Eagle's syndrome.
Egierska D, Perszke M, Kurianowicz I
Pol Merkur Lekarski 2021 Dec 16;49(294):458-460. PMID: 34919094
Recent advances in dysphagia management.
Triggs J, Pandolfino J
F1000Res 2019;8 Epub 2019 Aug 29 doi: 10.12688/f1000research.18900.1. PMID: 31508201Free PMC Article
Acute oesophageal symptoms.
Hossain SM, de Caestecker J
Clin Med (Lond) 2015 Oct;15(5):477-81. doi: 10.7861/clinmedicine.15-5-477. PMID: 26430190Free PMC Article
Radiation esophagitis.
Murro D, Jakate S
Arch Pathol Lab Med 2015 Jun;139(6):827-30. doi: 10.5858/arpa.2014-0111-RS. PMID: 26030254

Therapy

Results of Phase III Randomized Trial for Use of Docetaxel as a Radiosensitizer in Patients With Head and Neck Cancer, Unsuitable for Cisplatin-Based Chemoradiation.
Patil VM, Noronha V, Menon N, Singh A, Ghosh-Laskar S, Budrukkar A, Bhattacharjee A, Swain M, Mathrudev V, Nawale K, Balaji A, Peelay Z, Alone M, Pathak S, Mahajan A, Kumar S, Purandare N, Agarwal A, Puranik A, Pendse S, Reddy Yallala M, Sahu H, Kapu V, Dey S, Choudhary J, Krishna MR, Shetty A, Karuvandan N, Ravind R, Rai R, Jobanputra K, Chaturvedi P, Pai PS, Chaukar D, Nair S, Thiagarajan S, Prabhash K
J Clin Oncol 2023 May 1;41(13):2350-2361. Epub 2023 Jan 27 doi: 10.1200/JCO.22.00980. PMID: 36706347
Early side effects of radiation treatment for head and neck cancer.
Brook I
Cancer Radiother 2021 Jul;25(5):507-513. Epub 2021 Mar 5 doi: 10.1016/j.canrad.2021.02.001. PMID: 33685809
Efficacy of Budesonide Orodispersible Tablets as Induction Therapy for Eosinophilic Esophagitis in a Randomized Placebo-Controlled Trial.
Lucendo AJ, Miehlke S, Schlag C, Vieth M, von Arnim U, Molina-Infante J, Hartmann D, Bredenoord AJ, Ciriza de Los Rios C, Schubert S, Brückner S, Madisch A, Hayat J, Tack J, Attwood S, Mueller R, Greinwald R, Schoepfer A, Straumann A; International EOS-1 Study Group
Gastroenterology 2019 Jul;157(1):74-86.e15. Epub 2019 Mar 26 doi: 10.1053/j.gastro.2019.03.025. PMID: 30922997
Radiation esophagitis.
Murro D, Jakate S
Arch Pathol Lab Med 2015 Jun;139(6):827-30. doi: 10.5858/arpa.2014-0111-RS. PMID: 26030254
Candida esophagitis.
Mathieson R, Dutta SK
Dig Dis Sci 1983 Apr;28(4):365-70. doi: 10.1007/BF01324956. PMID: 6339183

Prognosis

ESNM/ANMS Review. Diagnosis and management of globus sensation: A clinical challenge.
Zerbib F, Rommel N, Pandolfino J, Gyawali CP
Neurogastroenterol Motil 2020 Sep;32(9):e13850. Epub 2020 Apr 23 doi: 10.1111/nmo.13850. PMID: 32329203
Radiation esophagitis.
Murro D, Jakate S
Arch Pathol Lab Med 2015 Jun;139(6):827-30. doi: 10.5858/arpa.2014-0111-RS. PMID: 26030254
Leiomyosarcoma of the tonsil.
Jones BF, Srinivasan V, Gumparthy K, Hughes D
J Laryngol Otol 2011 Aug;125(8):869-72. Epub 2011 Jun 8 doi: 10.1017/S0022215111001290. PMID: 21729441
Cicatricial pemphigoid.
Fleming TE, Korman NJ
J Am Acad Dermatol 2000 Oct;43(4):571-91; quiz 591-4. doi: 10.1067/mjd.2000.107248. PMID: 11004612
Adult supraglottitis.
Barrow HN, Vastola AP, Wang RC
Otolaryngol Head Neck Surg 1993 Sep;109(3 Pt 1):474-7. doi: 10.1177/019459989310900314. PMID: 8414565

Clinical prediction guides

High risk and low prevalence diseases: Adult epiglottitis.
Bridwell RE, Koyfman A, Long B
Am J Emerg Med 2022 Jul;57:14-20. Epub 2022 Apr 20 doi: 10.1016/j.ajem.2022.04.018. PMID: 35489220
Influence of Age and Sex on Clinical and Therapeutic Features of Laryngopharyngeal Reflux.
Lechien JR, Carroll TL, Bobin F, Muls V, Rodriguez A, Horoi M, Dequanter D, Crevier-Buchman L, Hans S, Saussez S
Otolaryngol Head Neck Surg 2022 Mar;166(3):468-476. Epub 2021 Jun 22 doi: 10.1177/01945998211020284. PMID: 34154447
Zika Virus-What the Otolaryngologist Should Know: A Review.
Arnaoutakis D, Padhya T
JAMA Otolaryngol Head Neck Surg 2017 Jan 1;143(1):81-84. doi: 10.1001/jamaoto.2016.3427. PMID: 27892990
Adult supraglottitis.
Barrow HN, Vastola AP, Wang RC
Otolaryngol Head Neck Surg 1993 Sep;109(3 Pt 1):474-7. doi: 10.1177/019459989310900314. PMID: 8414565
Esophageal foreign bodies.
Brady PG
Gastroenterol Clin North Am 1991 Dec;20(4):691-701. PMID: 1787010

Recent systematic reviews

Effectiveness of natural-based products for radiation-induced oral mucositis therapy: A systematic review.
Pranadwista ZF, Nur'aeny N
Cancer Treat Res Commun 2023;36:100720. Epub 2023 May 16 doi: 10.1016/j.ctarc.2023.100720. PMID: 37209466
Acute epiglottitis caused by COVID-19: A systematic review.
Meng X, Han C, Wang Y
Biomol Biomed 2023 Jul 3;23(4):568-574. doi: 10.17305/bb.2022.8861. PMID: 36946336Free PMC Article
Oesophageal Tuberculosis: A Systematic Review Focusing on Clinical Management.
Birda CL, Kumar A, Gupta P, Singh H, Sharma V
Dysphagia 2022 Aug;37(4):973-987. Epub 2021 Sep 4 doi: 10.1007/s00455-021-10360-x. PMID: 34482490
Dexamethasone reduces pain, vomiting and overall complications following tonsillectomy in adults: a systematic review and meta-analysis of randomised controlled trials.
Diakos EA, Gallos ID, El-Shunnar S, Clarke M, Kazi R, Mehanna H
Clin Otolaryngol 2011 Dec;36(6):531-42. doi: 10.1111/j.1749-4486.2011.02373.x. PMID: 21812940
Endoscopic treatments for Barrett's esophagus: a systematic review of safety and effectiveness compared to esophagectomy.
Menon D, Stafinski T, Wu H, Lau D, Wong C
BMC Gastroenterol 2010 Sep 27;10:111. doi: 10.1186/1471-230X-10-111. PMID: 20875123Free PMC Article

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