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Obstipation

MedGen UID:
526173
Concept ID:
C0221152
Disease or Syndrome
Synonyms: Intractable constipation; Lack of flatulence; No gas passage; Tympanic distended abdomen
SNOMED CT: Obstipation (111360009); Intractable constipation (111360009)
 
HPO: HP:0034782

Definition

Obstipation is the inability to pass either stool or flatus (gas). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVObstipation

Professional guidelines

PubMed

Colombel JF, Shin A, Gibson PR
Clin Gastroenterol Hepatol 2019 Feb;17(3):380-390.e1. Epub 2018 Aug 9 doi: 10.1016/j.cgh.2018.08.001. PMID: 30099108Free PMC Article
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Irani S, Kozarek RA
Curr Opin Gastroenterol 2015 Sep;31(5):339-50. doi: 10.1097/MOG.0000000000000200. PMID: 26247823

Recent clinical studies

Etiology

Gullaksen S, Vernstrøm L, Sørensen SS, Ringgaard S, Laustsen C, Funck KL, Poulsen PL, Laugesen E
Diabetologia 2023 May;66(5):813-825. Epub 2023 Feb 6 doi: 10.1007/s00125-023-05876-w. PMID: 36746803
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Khalayleh H, Koplewitz BZ, Kapuller V, Armon Y, Abu-Leil S, Arbell D
J Pediatr Surg 2016 Nov;51(11):1782-1785. Epub 2016 Jul 5 doi: 10.1016/j.jpedsurg.2016.06.017. PMID: 27444245
de Vrese M, Schrezenmeir J
Adv Biochem Eng Biotechnol 2008;111:1-66. doi: 10.1007/10_2008_097. PMID: 18461293
Kloeppel R, Rothe K, Hoermann D, Schmidt F, Bennek J, Kahn T
J Comput Assist Tomogr 2002 Mar-Apr;26(2):262-5. doi: 10.1097/00004728-200203000-00017. PMID: 11884784

Diagnosis

Sattler SS, Magro CM, Shapiro L, Merves JF, Levy R, Veenstra J, Patel P
Orphanet J Rare Dis 2022 Apr 20;17(1):172. doi: 10.1186/s13023-022-02322-9. PMID: 35443671Free PMC Article
Beg MY, Bains L, Lal P, Maranna H, Kumar N P
Ann R Coll Surg Engl 2020 Oct;102(8):571-576. Epub 2020 Jun 15 doi: 10.1308/rcsann.2020.0122. PMID: 32538120Free PMC Article
Colombel JF, Shin A, Gibson PR
Clin Gastroenterol Hepatol 2019 Feb;17(3):380-390.e1. Epub 2018 Aug 9 doi: 10.1016/j.cgh.2018.08.001. PMID: 30099108Free PMC Article
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Khalayleh H, Koplewitz BZ, Kapuller V, Armon Y, Abu-Leil S, Arbell D
J Pediatr Surg 2016 Nov;51(11):1782-1785. Epub 2016 Jul 5 doi: 10.1016/j.jpedsurg.2016.06.017. PMID: 27444245

Therapy

Gullaksen S, Vernstrøm L, Sørensen SS, Ringgaard S, Laustsen C, Funck KL, Poulsen PL, Laugesen E
Diabetologia 2023 May;66(5):813-825. Epub 2023 Feb 6 doi: 10.1007/s00125-023-05876-w. PMID: 36746803
Reis M, Gomes AM, Santos C, Lopes D, Fernandes JC
J Bras Nefrol 2022 Oct-Dec;44(4):587-591. doi: 10.1590/2175-8239-JBN-2021-0001. PMID: 33891672Free PMC Article
Barreiros AP, Galle PR, Otto G
Dig Dis 2013;31(1):170-4. Epub 2013 Jun 17 doi: 10.1159/000347214. PMID: 23797140
Rekand T, Hagen EM, Grønning M
Tidsskr Nor Laegeforen 2012 Apr 30;132(8):970-3. doi: 10.4045/tidsskr.10.0872. PMID: 22562332
de Vrese M, Schrezenmeir J
Adv Biochem Eng Biotechnol 2008;111:1-66. doi: 10.1007/10_2008_097. PMID: 18461293

Prognosis

Lai SH, Vogel JD
Dis Colon Rectum 2021 Apr 1;64(4):375-378. doi: 10.1097/DCR.0000000000001947. PMID: 33496483
Khalayleh H, Koplewitz BZ, Kapuller V, Armon Y, Abu-Leil S, Arbell D
J Pediatr Surg 2016 Nov;51(11):1782-1785. Epub 2016 Jul 5 doi: 10.1016/j.jpedsurg.2016.06.017. PMID: 27444245
Stillman M, Tailor M
N Engl J Med 2013 Nov 14;369(20):1880-1. Epub 2013 Oct 23 doi: 10.1056/NEJMp1312793. PMID: 24152232
Milla PJ
Baillieres Clin Gastroenterol 1998 Dec;12(4):775-97. doi: 10.1016/s0950-3528(98)90007-0. PMID: 10079906
Rintala R, Rapola J, Louhimo I
Prog Pediatr Surg 1989;24:186-92. doi: 10.1007/978-3-642-74493-8_20. PMID: 2513603

Clinical prediction guides

Algotsson C, Rosso A, Elmståhl S, Siennicki-Lantz A
Parkinsonism Relat Disord 2023 Jun;111:105416. Epub 2023 Apr 25 doi: 10.1016/j.parkreldis.2023.105416. PMID: 37130449
Abdalla TSA, Zimmermann M, Weisheit L, Thomaschewski M, Deichmann S, Nolde J, Keck T, Benecke C
Int J Colorectal Dis 2023 Jan 16;38(1):14. doi: 10.1007/s00384-023-04311-1. PMID: 36645511Free PMC Article
Stritter W, Rutert B, Eggert A, Längler A, Holmberg C, Seifert G
Integr Cancer Ther 2020 Jan-Dec;19:1534735420928393. doi: 10.1177/1534735420928393. PMID: 32646250Free PMC Article
Neville JJ, Gallagher J, Mitra A, Sheth H
World J Surg 2020 Jun;44(6):1771-1778. doi: 10.1007/s00268-020-05403-7. PMID: 32030442
Wolf H
Scand J Rheumatol Suppl 2000;113:37-45. doi: 10.1080/030097400446625. PMID: 11028830

Recent systematic reviews

Augustin G, Bruketa T, Kunjko K, Romić I, Mikuš M, Vrbanić A, Tropea A
Updates Surg 2023 Aug;75(5):1071-1082. Epub 2023 May 20 doi: 10.1007/s13304-023-01537-0. PMID: 37209317
Neville JJ, Gallagher J, Mitra A, Sheth H
World J Surg 2020 Jun;44(6):1771-1778. doi: 10.1007/s00268-020-05403-7. PMID: 32030442
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845

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