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Tarsal tunnel syndrome

MedGen UID:
52646
•Concept ID:
C0039319
•
Disease or Syndrome
Synonyms: Neuropathy of the posterior tibial nerve and its branches; Posterior Tibial Nerve Neuralgia
SNOMED CT: TTS - Tarsal tunnel syndrome (47374004); Tarsal tunnel syndrome (ankle condition) (47374004); Tarsal tunnel syndrome (47374004)
 
Monarch Initiative: MONDO:0006994

Definition

A syndrome resulting from the entrapment and compression of the tibial nerve. Signs and symptoms include burning sensation, tingling, and pain in the foot sole. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTarsal tunnel syndrome

Professional guidelines

PubMed

Rearfoot disorders and conservative treatment: a narrative review.
Choo YJ, Park CH, Chang MC
Ann Palliat Med 2020 Sep;9(5):3546-3552. Epub 2020 Aug 6 doi: 10.21037/apm-20-446. PMID: 32787369
Heel Pain: Diagnosis and Management.
Tu P
Am Fam Physician 2018 Jan 15;97(2):86-93. PMID: 29365222
Peripheral nerve injuries in athletes. Treatment and prevention.
Lorei MP, Hershman EB
Sports Med 1993 Aug;16(2):130-47. doi: 10.2165/00007256-199316020-00005. PMID: 8378668

Recent clinical studies

Etiology

Tarsal Tunnel Syndrome: Outcome According to Etiology.
Lalevée M, Coillard JY, Gauthé R, Dechelotte B, Fantino O, Boublil D, Grisard JL, Viste A, Klouche S, Bouysset M
J Foot Ankle Surg 2022 May-Jun;61(3):583-589. Epub 2021 Oct 23 doi: 10.1053/j.jfas.2021.10.014. PMID: 34799273
Calcaneal osteotomy for hindfoot deformity.
Brilhault J
Orthop Traumatol Surg Res 2022 Feb;108(1S):103121. Epub 2021 Oct 20 doi: 10.1016/j.otsr.2021.103121. PMID: 34687951
Tarsal tunnel syndrome-A narrative literature review.
McSweeney SC, Cichero M
Foot (Edinb) 2015 Dec;25(4):244-50. Epub 2015 Sep 12 doi: 10.1016/j.foot.2015.08.008. PMID: 26546070
Controversial entrapment neuropathies.
Campbell WW, Landau ME
Neurosurg Clin N Am 2008 Oct;19(4):597-608, vi-vii. doi: 10.1016/j.nec.2008.07.001. PMID: 19010284
Entrapment neuropathies.
Murthy JM, Meena AK
J Assoc Physicians India 1995 Oct;43(10):673-5. PMID: 8773001

Diagnosis

Tarsal Tunnel Syndrome.
Nelson SC
Clin Podiatr Med Surg 2021 Apr;38(2):131-141. doi: 10.1016/j.cpm.2020.12.001. PMID: 33745647
Entrapment Neuropathies of the Lower Extremity.
Bowley MP, Doughty CT
Med Clin North Am 2019 Mar;103(2):371-382. Epub 2018 Dec 3 doi: 10.1016/j.mcna.2018.10.013. PMID: 30704688
Heel Pain: Diagnosis and Management.
Tu P
Am Fam Physician 2018 Jan 15;97(2):86-93. PMID: 29365222
Tarsal tunnel syndrome-A narrative literature review.
McSweeney SC, Cichero M
Foot (Edinb) 2015 Dec;25(4):244-50. Epub 2015 Sep 12 doi: 10.1016/j.foot.2015.08.008. PMID: 26546070
Diagnosis of heel pain.
Tu P, Bytomski JR
Am Fam Physician 2011 Oct 15;84(8):909-16. PMID: 22010770

Therapy

Acupotomy for patients with tarsal tunnel syndrome: A protocol for systematic review and meta analysis.
Sun X, Zhou Q, Shi C, Lan Y, Jia Y, Qiu Z, Shen Y, Li S
Medicine (Baltimore) 2020 Sep 25;99(39):e22369. doi: 10.1097/MD.0000000000022369. PMID: 32991456Free PMC Article
Peripheral Nerve Stimulation for the 21st Century: Sural, Superficial Peroneal, and Tibial Nerves.
Hanyu-Deutmeyer A, Pritzlaff SG
Pain Med 2020 Aug 1;21(Suppl 1):S64-S67. doi: 10.1093/pm/pnaa202. PMID: 32804232
Managing the patient with heel pain.
Bhatty UN, Khan SH, Zubairy AI
Br J Hosp Med (Lond) 2019 Apr 2;80(4):196-200. doi: 10.12968/hmed.2019.80.4.196. PMID: 30951414
Tarsal tunnel syndrome-A narrative literature review.
McSweeney SC, Cichero M
Foot (Edinb) 2015 Dec;25(4):244-50. Epub 2015 Sep 12 doi: 10.1016/j.foot.2015.08.008. PMID: 26546070
Considerations in footwear and orthotics.
Khan MN, Jacobs BC, Ashbaugh S
Prim Care 2013 Dec;40(4):1001-12, x. Epub 2013 Oct 15 doi: 10.1016/j.pop.2013.08.013. PMID: 24209730

Prognosis

Tarsal tunnel syndrome-A narrative literature review.
McSweeney SC, Cichero M
Foot (Edinb) 2015 Dec;25(4):244-50. Epub 2015 Sep 12 doi: 10.1016/j.foot.2015.08.008. PMID: 26546070
Tarsal tunnel syndrome: A literature review.
Ahmad M, Tsang K, Mackenney PJ, Adedapo AO
Foot Ankle Surg 2012 Sep;18(3):149-52. Epub 2011 Dec 21 doi: 10.1016/j.fas.2011.10.007. PMID: 22857954
Diagnosis of heel pain.
Tu P, Bytomski JR
Am Fam Physician 2011 Oct 15;84(8):909-16. PMID: 22010770
Peripheral nerve entrapments.
Hirose CB, McGarvey WC
Foot Ankle Clin 2004 Jun;9(2):255-69. doi: 10.1016/j.fcl.2004.02.001. PMID: 15165581
Tarsal tunnel syndrome: review of the literature.
Cimino WR
Foot Ankle 1990 Aug;11(1):47-52. doi: 10.1177/107110079001100110. PMID: 2210534

Clinical prediction guides

Patient Satisfaction with Surgery for Tarsal- and Carpal- Tunnel Syndrome - Comparative Study.
Kokubo R, Kim K, Isu T, Morimoto D, Morita A
Neurol Med Chir (Tokyo) 2023 Mar 15;63(3):116-121. Epub 2023 Jan 20 doi: 10.2176/jns-nmc.2022-0245. PMID: 36682791Free PMC Article
The prevalence of tarsal tunnel syndrome in patients with lumbosacral radiculopathy.
Zheng C, Zhu Y, Jiang J, Ma X, Lu F, Jin X, Weber R
Eur Spine J 2016 Mar;25(3):895-905. Epub 2015 Sep 25 doi: 10.1007/s00586-015-4246-x. PMID: 26407567
Neurologic involvement in scleroderma: a systematic review.
Amaral TN, Peres FA, Lapa AT, Marques-Neto JF, Appenzeller S
Semin Arthritis Rheum 2013 Dec;43(3):335-47. Epub 2013 Jul 1 doi: 10.1016/j.semarthrit.2013.05.002. PMID: 23827688
Tarsal tunnel syndrome: A literature review.
Ahmad M, Tsang K, Mackenney PJ, Adedapo AO
Foot Ankle Surg 2012 Sep;18(3):149-52. Epub 2011 Dec 21 doi: 10.1016/j.fas.2011.10.007. PMID: 22857954
Tarsal tunnel syndrome: diagnosis, surgical technique, and functional outcome.
Bailie DS, Kelikian AS
Foot Ankle Int 1998 Feb;19(2):65-72. doi: 10.1177/107110079801900203. PMID: 9498577

Recent systematic reviews

Tarsal tunnel syndrome secondary to accessory or variant muscles: a clinical and anatomical systematic review.
Yammine K, Daher JC, Tannoury EH, Assi C
Surg Radiol Anat 2022 May;44(5):645-657. Epub 2022 Mar 30 doi: 10.1007/s00276-022-02932-9. PMID: 35353216
Anatomical characteristics of the flexor digitorum accessorius longus muscle and their relevance to tarsal tunnel syndrome a systematic review.
Deleu PA, Bevernage BD, Birch I, Maldague P, Gombault V, Leemrijse T
J Am Podiatr Med Assoc 2015 Jul;105(4):344-55. doi: 10.7547/13-084.1. PMID: 26218158
Outcomes and safety of endoscopic tarsal tunnel decompression: a systematic review.
Gkotsoulias EN, Simonson DC, Roukis TS
Foot Ankle Spec 2014 Feb;7(1):57-60. Epub 2013 Dec 10 doi: 10.1177/1938640013514267. PMID: 24334368
Neurologic involvement in scleroderma: a systematic review.
Amaral TN, Peres FA, Lapa AT, Marques-Neto JF, Appenzeller S
Semin Arthritis Rheum 2013 Dec;43(3):335-47. Epub 2013 Jul 1 doi: 10.1016/j.semarthrit.2013.05.002. PMID: 23827688

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