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Thalamic disorder

MedGen UID:
52693
•Concept ID:
C0039726
•
Disease or Syndrome
Synonym: Thalamic disease
 
Monarch Initiative: MONDO:0003081

Definition

A disorder of the thalamus. Causes include brain neoplasms, cerebrovascular disorders, brain trauma, brain hypoxia, infections, and brain hemorrhage. Signs and symptoms include movement and sensory abnormalities, visual abnormalities, ataxia, and coma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThalamic disorder

Professional guidelines

PubMed

Post-stroke Movement Disorders: Clinical Spectrum, Pathogenesis, and Management.
Tater P, Pandey S
Neurol India 2021 Mar-Apr;69(2):272-283. doi: 10.4103/0028-3886.314574. PMID: 33904435
Neuropathic Pain: From Mechanisms to Treatment.
Finnerup NB, Kuner R, Jensen TS
Physiol Rev 2021 Jan 1;101(1):259-301. Epub 2020 Jun 25 doi: 10.1152/physrev.00045.2019. PMID: 32584191
Essential tremor: diagnosis and management.
Shanker V
BMJ 2019 Aug 5;366:l4485. doi: 10.1136/bmj.l4485. PMID: 31383632

Recent clinical studies

Etiology

A multi-contrast MRI approach to thalamus segmentation.
Corona V, Lellmann J, Nestor P, Schönlieb CB, Acosta-Cabronero J
Hum Brain Mapp 2020 Jun 1;41(8):2104-2120. Epub 2020 Jan 20 doi: 10.1002/hbm.24933. PMID: 31957926Free PMC Article
Leksell Radiosurgery for Movement Disorders.
Niranjan A, Raju SS, Lunsford LD
Prog Neurol Surg 2019;34:279-288. Epub 2019 May 16 doi: 10.1159/000493075. PMID: 31096233
Dopamine, fronto-striato-thalamic circuits and risk for psychosis.
Dandash O, Pantelis C, Fornito A
Schizophr Res 2017 Feb;180:48-57. Epub 2016 Aug 29 doi: 10.1016/j.schres.2016.08.020. PMID: 27595552
The Role of Thalamic Damage in Mild Traumatic Brain Injury.
Grossman EJ, Inglese M
J Neurotrauma 2016 Jan 15;33(2):163-7. Epub 2015 Aug 5 doi: 10.1089/neu.2015.3965. PMID: 26054745Free PMC Article
Thalamotomy for movement disorders.
Burchiel KJ
Neurosurg Clin N Am 1995 Jan;6(1):55-71. PMID: 7696875

Diagnosis

Cheiro-Oral syndrome.
Manning S, King BR, Peffer J, Lescure D
Am J Emerg Med 2021 Jan;39:151-153. Epub 2020 Oct 1 doi: 10.1016/j.ajem.2020.09.064. PMID: 33039224
Cheiro-Oral Syndrome.
Thapa L , Amatya R , Maharjan S , Gaurishankar N , Shrestha AM , Bhattarai S , Singh SN , Gongal DN , Devkota UP
Kathmandu Univ Med J (KUMJ) 2018 Apr-Jun;16(62):196-198. PMID: 30636764
Dopamine, fronto-striato-thalamic circuits and risk for psychosis.
Dandash O, Pantelis C, Fornito A
Schizophr Res 2017 Feb;180:48-57. Epub 2016 Aug 29 doi: 10.1016/j.schres.2016.08.020. PMID: 27595552
Wyburn-Mason Syndrome.
Kolomeyer AM, Laviolette R, Winter TW
Ophthalmology 2016 Jan;123(1):50. doi: 10.1016/j.ophtha.2015.10.033. PMID: 26707436
Peduncular hallucinations.
Kölmel HW
J Neurol 1991 Dec;238(8):457-9. doi: 10.1007/BF00314654. PMID: 1779254

Therapy

Comparative neural correlates of DBS and MRgFUS lesioning for tremor control in essential tremor.
Germann J, Santyr B, Boutet A, Sarica C, Chow CT, Elias GJB, Vetkas A, Yang A, Hodaie M, Fasano A, Kalia SK, Schwartz ML, Lozano AM
J Neurol Neurosurg Psychiatry 2024 Jan 11;95(2):180-183. doi: 10.1136/jnnp-2022-330795. PMID: 37722831Free PMC Article
Tremor.
Louis ED
Continuum (Minneap Minn) 2019 Aug;25(4):959-975. doi: 10.1212/CON.0000000000000748. PMID: 31356289
Clinical characteristics of autoimmune GFAP astrocytopathy.
Kimura A, Takekoshi A, Yoshikura N, Hayashi Y, Shimohata T
J Neuroimmunol 2019 Jul 15;332:91-98. Epub 2019 Apr 9 doi: 10.1016/j.jneuroim.2019.04.004. PMID: 30991306
Current understanding of thalamic structure and function in migraine.
Younis S, Hougaard A, Noseda R, Ashina M
Cephalalgia 2019 Nov;39(13):1675-1682. Epub 2018 Aug 4 doi: 10.1177/0333102418791595. PMID: 30079744Free PMC Article
Surgery for Tourette syndrome.
Ackermans L, Kuhn J, Neuner I, Temel Y, Visser-Vandewalle V
World Neurosurg 2013 Sep-Oct;80(3-4):S29.e15-22. Epub 2012 Jun 19 doi: 10.1016/j.wneu.2012.06.017. PMID: 22722039

Prognosis

Towards network-guided neuromodulation for epilepsy.
Piper RJ, Richardson RM, Worrell G, Carmichael DW, Baldeweg T, Litt B, Denison T, Tisdall MM
Brain 2022 Oct 21;145(10):3347-3362. doi: 10.1093/brain/awac234. PMID: 35771657Free PMC Article
The Mediodorsal Thalamus: An Essential Partner of the Prefrontal Cortex for Cognition.
Parnaudeau S, Bolkan SS, Kellendonk C
Biol Psychiatry 2018 Apr 15;83(8):648-656. Epub 2017 Nov 15 doi: 10.1016/j.biopsych.2017.11.008. PMID: 29275841Free PMC Article
3D fully convolutional networks for subcortical segmentation in MRI: A large-scale study.
Dolz J, Desrosiers C, Ben Ayed I
Neuroimage 2018 Apr 15;170:456-470. Epub 2017 Apr 24 doi: 10.1016/j.neuroimage.2017.04.039. PMID: 28450139
Review of thalamocortical resting-state fMRI studies in schizophrenia.
Giraldo-Chica M, Woodward ND
Schizophr Res 2017 Feb;180:58-63. Epub 2016 Aug 13 doi: 10.1016/j.schres.2016.08.005. PMID: 27531067Free PMC Article
Neural network models of tinnitus.
Husain FT
Prog Brain Res 2007;166:125-40. doi: 10.1016/S0079-6123(07)66011-7. PMID: 17956777

Clinical prediction guides

Deep posteromedial cortical rhythm in dissociation.
Vesuna S, Kauvar IV, Richman E, Gore F, Oskotsky T, Sava-Segal C, Luo L, Malenka RC, Henderson JM, Nuyujukian P, Parvizi J, Deisseroth K
Nature 2020 Oct;586(7827):87-94. Epub 2020 Sep 16 doi: 10.1038/s41586-020-2731-9. PMID: 32939091Free PMC Article
Thalamic abnormalities are a cardinal feature of alcohol-related brain dysfunction.
Pitel AL, Segobin SH, Ritz L, Eustache F, Beaunieux H
Neurosci Biobehav Rev 2015 Jul;54:38-45. Epub 2014 Aug 6 doi: 10.1016/j.neubiorev.2014.07.023. PMID: 25108034
Functional anatomy of thalamus and basal ganglia.
Herrero MT, Barcia C, Navarro JM
Childs Nerv Syst 2002 Aug;18(8):386-404. Epub 2002 Jul 26 doi: 10.1007/s00381-002-0604-1. PMID: 12192499
The role of the thalamus in functional neurosurgery.
Tasker RR, Kiss ZH
Neurosurg Clin N Am 1995 Jan;6(1):73-104. PMID: 7696876
Paramedian diencephalic syndrome.
Antonini G, Rasura M, Paolini S, Mercieri M, Pantano P, Gragnani F, Argentino C
Ital J Neurol Sci 1994 Sep;15(6):285-90. doi: 10.1007/BF02339238. PMID: 7843943

Recent systematic reviews

Neurochemical Alterations in Social Anxiety Disorder (SAD): A Systematic Review of Proton Magnetic Resonance Spectroscopic Studies.
Elsaid S, Rubin-Kahana DS, Kloiber S, Kennedy SH, Chavez S, Le Foll B
Int J Mol Sci 2022 Apr 26;23(9) doi: 10.3390/ijms23094754. PMID: 35563145Free PMC Article
Neurobiological underpinnings of bipolar disorder focusing on findings of diffusion tensor imaging: a systematic review.
Duarte JA, de Araújo E Silva JQ, Goldani AA, Massuda R, Gama CS
Braz J Psychiatry 2016 Mar 22;38(2):167-75. doi: 10.1590/1516-4446-2015-1793. PMID: 27007148Free PMC Article
Deep Brain Stimulation for Tourette-Syndrome: A Systematic Review and Meta-Analysis.
Baldermann JC, Schüller T, Huys D, Becker I, Timmermann L, Jessen F, Visser-Vandewalle V, Kuhn J
Brain Stimul 2016 Mar-Apr;9(2):296-304. Epub 2015 Dec 29 doi: 10.1016/j.brs.2015.11.005. PMID: 26827109
A systematic review of the neural bases of psychotherapy for anxiety and related disorders.
Brooks SJ, Stein DJ
Dialogues Clin Neurosci 2015 Sep;17(3):261-79. doi: 10.31887/DCNS.2015.17.3/sbrooks. PMID: 26487807Free PMC Article
A systematic review of resting-state functional-MRI studies in major depression.
Wang L, Hermens DF, Hickie IB, Lagopoulos J
J Affect Disord 2012 Dec 15;142(1-3):6-12. Epub 2012 Jul 31 doi: 10.1016/j.jad.2012.04.013. PMID: 22858266

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