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Gastrointestinal tuberculosis

MedGen UID:
52885
•Concept ID:
C0041312
•
Disease or Syndrome
Synonyms: Gastrointestinal Tuberculosis; Tuberculosis, Gastrointestinal
SNOMED CT: Tuberculosis of gastrointestinal tract (240376003)
 
Monarch Initiative: MONDO:0005768

Definition

Tuberculosis that involves any region of the gastrointestinal tract, mostly in the distal ileum and the cecum. In most cases, mycobacterium tuberculosis is the pathogen. Clinical features include abdominal pain; fever; and palpable mass in the ileocecal area. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGastrointestinal tuberculosis

Professional guidelines

PubMed

Evidence-based approach to diagnosis and management of abdominal tuberculosis.
Jha DK, Pathiyil MM, Sharma V
Indian J Gastroenterol 2023 Feb;42(1):17-31. Epub 2023 Mar 11 doi: 10.1007/s12664-023-01343-x. PMID: 36899289Free PMC Article
Gastrointestinal tuberculosis: A systematic review of epidemiology, presentation, diagnosis and treatment.
Al-Zanbagi AB, Shariff MK
Saudi J Gastroenterol 2021 Sep-Oct;27(5):261-274. doi: 10.4103/sjg.sjg_148_21. PMID: 34213424Free PMC Article
Intestinal tuberculosis and Crohn's disease: challenging differential diagnosis.
Ma JY, Tong JL, Ran ZH
J Dig Dis 2016 Mar;17(3):155-61. doi: 10.1111/1751-2980.12324. PMID: 26854750

Recent clinical studies

Etiology

Gastrointestinal tuberculosis: A systematic review of epidemiology, presentation, diagnosis and treatment.
Al-Zanbagi AB, Shariff MK
Saudi J Gastroenterol 2021 Sep-Oct;27(5):261-274. doi: 10.4103/sjg.sjg_148_21. PMID: 34213424Free PMC Article
Small bowel strictures.
Durmush D, Kaffes AJ
Curr Opin Gastroenterol 2019 May;35(3):235-242. doi: 10.1097/MOG.0000000000000531. PMID: 30865041
Intestinal tuberculosis.
Donoghue HD, Holton J
Curr Opin Infect Dis 2009 Oct;22(5):490-6. doi: 10.1097/QCO.0b013e3283306712. PMID: 19623062
Extrapulmonary tuberculosis: an overview.
Golden MP, Vikram HR
Am Fam Physician 2005 Nov 1;72(9):1761-8. PMID: 16300038
Gastrointestinal tuberculosis.
Sheer TA, Coyle WJ
Curr Gastroenterol Rep 2003 Aug;5(4):273-8. doi: 10.1007/s11894-003-0063-1. PMID: 12864956

Diagnosis

Evidence-based approach to diagnosis and management of abdominal tuberculosis.
Jha DK, Pathiyil MM, Sharma V
Indian J Gastroenterol 2023 Feb;42(1):17-31. Epub 2023 Mar 11 doi: 10.1007/s12664-023-01343-x. PMID: 36899289Free PMC Article
Gastrointestinal tuberculosis: A systematic review of epidemiology, presentation, diagnosis and treatment.
Al-Zanbagi AB, Shariff MK
Saudi J Gastroenterol 2021 Sep-Oct;27(5):261-274. doi: 10.4103/sjg.sjg_148_21. PMID: 34213424Free PMC Article
Gastrointestinal and Abdominal Tuberculosis.
Eraksoy H
Gastroenterol Clin North Am 2021 Jun;50(2):341-360. doi: 10.1016/j.gtc.2021.02.004. PMID: 34024445
Gastrointestinal Tuberculosis.
Choi EH, Coyle WJ
Microbiol Spectr 2016 Dec;4(6) doi: 10.1128/microbiolspec.TNMI7-0014-2016. PMID: 28084201
Gastrointestinal tuberculosis.
Sheer TA, Coyle WJ
Curr Gastroenterol Rep 2003 Aug;5(4):273-8. doi: 10.1007/s11894-003-0063-1. PMID: 12864956

Therapy

Gastric tuberculosis.
Chaudhary P, Khan AQ, Lal R, Bhadana U
Indian J Tuberc 2019 Jul;66(3):411-417. Epub 2018 Nov 10 doi: 10.1016/j.ijtb.2018.10.004. PMID: 31439189
Differentiating Crohn's disease from intestinal tuberculosis.
Kedia S, Das P, Madhusudhan KS, Dattagupta S, Sharma R, Sahni P, Makharia G, Ahuja V
World J Gastroenterol 2019 Jan 28;25(4):418-432. doi: 10.3748/wjg.v25.i4.418. PMID: 30700939Free PMC Article
Gastrointestinal Tuberculosis.
Choi EH, Coyle WJ
Microbiol Spectr 2016 Dec;4(6) doi: 10.1128/microbiolspec.TNMI7-0014-2016. PMID: 28084201
Abdominal Tuberculosis.
Rathi P, Gambhire P
J Assoc Physicians India 2016 Feb;64(2):38-47. PMID: 27730779
Gastrointestinal tuberculosis.
Sheer TA, Coyle WJ
Curr Gastroenterol Rep 2003 Aug;5(4):273-8. doi: 10.1007/s11894-003-0063-1. PMID: 12864956

Prognosis

Differentiating gastrointestinal tuberculosis and Crohn's disease- a comprehensive review.
Choudhury A, Dhillon J, Sekar A, Gupta P, Singh H, Sharma V
BMC Gastroenterol 2023 Jul 19;23(1):246. doi: 10.1186/s12876-023-02887-0. PMID: 37468869Free PMC Article
Applying logistic LASSO regression for the diagnosis of atypical Crohn's disease.
Li Y, Lu F, Yin Y
Sci Rep 2022 Jul 5;12(1):11340. doi: 10.1038/s41598-022-15609-5. PMID: 35790774Free PMC Article
Differentiating Crohn's disease from intestinal tuberculosis.
Kedia S, Das P, Madhusudhan KS, Dattagupta S, Sharma R, Sahni P, Makharia G, Ahuja V
World J Gastroenterol 2019 Jan 28;25(4):418-432. doi: 10.3748/wjg.v25.i4.418. PMID: 30700939Free PMC Article
Extrapulmonary tuberculosis: an overview.
Golden MP, Vikram HR
Am Fam Physician 2005 Nov 1;72(9):1761-8. PMID: 16300038
Abdominal tuberculosis.
Kapoor VK
Postgrad Med J 1998 Aug;74(874):459-67. doi: 10.1136/pgmj.74.874.459. PMID: 9926119Free PMC Article

Clinical prediction guides

Differentiating gastrointestinal tuberculosis and Crohn's disease- a comprehensive review.
Choudhury A, Dhillon J, Sekar A, Gupta P, Singh H, Sharma V
BMC Gastroenterol 2023 Jul 19;23(1):246. doi: 10.1186/s12876-023-02887-0. PMID: 37468869Free PMC Article
Applying logistic LASSO regression for the diagnosis of atypical Crohn's disease.
Li Y, Lu F, Yin Y
Sci Rep 2022 Jul 5;12(1):11340. doi: 10.1038/s41598-022-15609-5. PMID: 35790774Free PMC Article
Differentiating Crohn's disease from intestinal tuberculosis.
Kedia S, Das P, Madhusudhan KS, Dattagupta S, Sharma R, Sahni P, Makharia G, Ahuja V
World J Gastroenterol 2019 Jan 28;25(4):418-432. doi: 10.3748/wjg.v25.i4.418. PMID: 30700939Free PMC Article
Gastrointestinal Tuberculosis.
Choi EH, Coyle WJ
Microbiol Spectr 2016 Dec;4(6) doi: 10.1128/microbiolspec.TNMI7-0014-2016. PMID: 28084201
Abdominal Tuberculosis.
Rathi P, Gambhire P
J Assoc Physicians India 2016 Feb;64(2):38-47. PMID: 27730779

Recent systematic reviews

Artificial intelligence for discrimination of Crohn's disease and gastrointestinal tuberculosis: A systematic review.
Sachan A, Kakadiya R, Mishra S, Kumar-M P, Jena A, Gupta P, Sebastian S, Deepak P, Sharma V
J Gastroenterol Hepatol 2024 Mar;39(3):422-430. Epub 2023 Dec 6 doi: 10.1111/jgh.16430. PMID: 38058246
Frequency, outcomes, and need for intervention in stricturing gastrointestinal tuberculosis: a systematic review and meta-analysis.
Jena A, Mohindra R, Rana K, Neelam PB, Thakur DC, Singh H, Gupta P, Suri V, Sharma V
BMC Gastroenterol 2023 Feb 23;23(1):46. doi: 10.1186/s12876-023-02682-x. PMID: 36814249Free PMC Article
Oesophageal Tuberculosis: A Systematic Review Focusing on Clinical Management.
Birda CL, Kumar A, Gupta P, Singh H, Sharma V
Dysphagia 2022 Aug;37(4):973-987. Epub 2021 Sep 4 doi: 10.1007/s00455-021-10360-x. PMID: 34482490
Gastrointestinal tuberculosis: A systematic review of epidemiology, presentation, diagnosis and treatment.
Al-Zanbagi AB, Shariff MK
Saudi J Gastroenterol 2021 Sep-Oct;27(5):261-274. doi: 10.4103/sjg.sjg_148_21. PMID: 34213424Free PMC Article
Tubercular Abdominal Cocoon: Systematic Review of an Uncommon Form of Tuberculosis.
Sharma V, Singh H, Mandavdhare HS
Surg Infect (Larchmt) 2017 Aug/Sep;18(6):736-741. Epub 2017 Jul 31 doi: 10.1089/sur.2017.110. PMID: 28759335

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