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Psychogenic syncope

MedGen UID:
536371
•Concept ID:
C0235245
•
Mental or Behavioral Dysfunction
Synonym: Psychogenic Syncope
SNOMED CT: Psychogenic syncope (386572005)

Definition

A condition in which syncope occurs due to a conversion disorder. (ACC-AHA) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPsychogenic syncope

Professional guidelines

PubMed

Utility of serum lactate on differential diagnosis of seizure-like activity: A systematic review and meta-analysis.
Patel J, Tran QK, Martinez S, Wright H, Pourmand A
Seizure 2022 Nov;102:134-142. Epub 2022 Oct 7 doi: 10.1016/j.seizure.2022.10.007. PMID: 36242832
Diagnostic criteria to aid the differential diagnosis of patients presenting with transient loss of consciousness: A systematic review.
Wardrope A, Newberry E, Reuber M
Seizure 2018 Oct;61:139-148. Epub 2018 Aug 16 doi: 10.1016/j.seizure.2018.08.012. PMID: 30145472
Psychogenic pseudosyncope: diagnosis and management.
Raj V, Rowe AA, Fleisch SB, Paranjape SY, Arain AM, Nicolson SE
Auton Neurosci 2014 Sep;184:66-72. Epub 2014 May 16 doi: 10.1016/j.autneu.2014.05.003. PMID: 24882462

Recent clinical studies

Etiology

Near-infrared Spectroscopy to Assess Cerebral Perfusion during Head-up Tilt-table Test in Patients with Syncope.
Ayers MD, Lawrence DK
Congenit Heart Dis 2015 Jul-Aug;10(4):333-9. Epub 2014 Nov 24 doi: 10.1111/chd.12236. PMID: 25421641
Predictive models of syncope causes in an outpatient clinic.
Graf D, Schlaepfer J, Gollut E, van Melle G, Mischler C, Fromer M, Kappenberger L, Pruvot E
Int J Cardiol 2008 Jan 24;123(3):249-56. Epub 2007 Mar 29 doi: 10.1016/j.ijcard.2006.12.007. PMID: 17397948
Long-term follow-up of children and adolescents with syncope; predictor of syncope recurrence.
Kouakam C, Vaksmann G, Pachy E, Lacroix D, Rey C, Kacet S
Eur Heart J 2001 Sep;22(17):1618-25. doi: 10.1053/euhj.2000.2577. PMID: 11492992
Inadequate sympathovagal balance in response to orthostatism in patients with unexplained syncope and a positive head up tilt test.
Kouakam C, Lacroix D, Zghal N, Logier R, Klug D, Le Franc P, Jarwe M, Kacet S
Heart 1999 Sep;82(3):312-8. doi: 10.1136/hrt.82.3.312. PMID: 10455081Free PMC Article
Evaluation of prognostic classifications for patients with syncope.
Eagle KA, Black HR, Cook EF, Goldman L
Am J Med 1985 Oct;79(4):455-60. doi: 10.1016/0002-9343(85)90032-4. PMID: 4050832

Diagnosis

Devil is in the detail.
Jacob JR, Paul A, Alex AG
BMJ Case Rep 2018 Apr 17;2018 doi: 10.1136/bcr-2017-224134. PMID: 29666096Free PMC Article
Stepwise evaluation of unexplained syncope in a large ambulatory population.
Iglesias JF, Graf D, Forclaz A, Schlaepfer J, Fromer M, Pruvot E
Pacing Clin Electrophysiol 2009 Mar;32 Suppl 1:S202-6. doi: 10.1111/j.1540-8159.2008.02291.x. PMID: 19250095
Predictive models of syncope causes in an outpatient clinic.
Graf D, Schlaepfer J, Gollut E, van Melle G, Mischler C, Fromer M, Kappenberger L, Pruvot E
Int J Cardiol 2008 Jan 24;123(3):249-56. Epub 2007 Mar 29 doi: 10.1016/j.ijcard.2006.12.007. PMID: 17397948
Long-term follow-up of children and adolescents with syncope; predictor of syncope recurrence.
Kouakam C, Vaksmann G, Pachy E, Lacroix D, Rey C, Kacet S
Eur Heart J 2001 Sep;22(17):1618-25. doi: 10.1053/euhj.2000.2577. PMID: 11492992
Syncope and seizures of psychogenic origin: identification with head-upright tilt table testing.
Grubb BP, Gerard G, Wolfe DA, Samoil D, Davenport CW, Homan RW, Temesy-Armos P
Clin Cardiol 1992 Nov;15(11):839-42. doi: 10.1002/clc.4960151109. PMID: 10969628

Therapy

Devil is in the detail.
Jacob JR, Paul A, Alex AG
BMJ Case Rep 2018 Apr 17;2018 doi: 10.1136/bcr-2017-224134. PMID: 29666096Free PMC Article
Hypoglycemia as a possible factor in the induction of vasovagal syncope.
Salins PC, Kuriakose M, Sharma SM, Tauro DP
Oral Surg Oral Med Oral Pathol 1992 Nov;74(5):544-9. doi: 10.1016/0030-4220(92)90340-v. PMID: 1437055

Prognosis

Near-infrared Spectroscopy to Assess Cerebral Perfusion during Head-up Tilt-table Test in Patients with Syncope.
Ayers MD, Lawrence DK
Congenit Heart Dis 2015 Jul-Aug;10(4):333-9. Epub 2014 Nov 24 doi: 10.1111/chd.12236. PMID: 25421641
Stepwise evaluation of unexplained syncope in a large ambulatory population.
Iglesias JF, Graf D, Forclaz A, Schlaepfer J, Fromer M, Pruvot E
Pacing Clin Electrophysiol 2009 Mar;32 Suppl 1:S202-6. doi: 10.1111/j.1540-8159.2008.02291.x. PMID: 19250095
Predictive models of syncope causes in an outpatient clinic.
Graf D, Schlaepfer J, Gollut E, van Melle G, Mischler C, Fromer M, Kappenberger L, Pruvot E
Int J Cardiol 2008 Jan 24;123(3):249-56. Epub 2007 Mar 29 doi: 10.1016/j.ijcard.2006.12.007. PMID: 17397948
Long-term follow-up of children and adolescents with syncope; predictor of syncope recurrence.
Kouakam C, Vaksmann G, Pachy E, Lacroix D, Rey C, Kacet S
Eur Heart J 2001 Sep;22(17):1618-25. doi: 10.1053/euhj.2000.2577. PMID: 11492992
Inadequate sympathovagal balance in response to orthostatism in patients with unexplained syncope and a positive head up tilt test.
Kouakam C, Lacroix D, Zghal N, Logier R, Klug D, Le Franc P, Jarwe M, Kacet S
Heart 1999 Sep;82(3):312-8. doi: 10.1136/hrt.82.3.312. PMID: 10455081Free PMC Article

Clinical prediction guides

Near-infrared Spectroscopy to Assess Cerebral Perfusion during Head-up Tilt-table Test in Patients with Syncope.
Ayers MD, Lawrence DK
Congenit Heart Dis 2015 Jul-Aug;10(4):333-9. Epub 2014 Nov 24 doi: 10.1111/chd.12236. PMID: 25421641
Predictive models of syncope causes in an outpatient clinic.
Graf D, Schlaepfer J, Gollut E, van Melle G, Mischler C, Fromer M, Kappenberger L, Pruvot E
Int J Cardiol 2008 Jan 24;123(3):249-56. Epub 2007 Mar 29 doi: 10.1016/j.ijcard.2006.12.007. PMID: 17397948
Long-term follow-up of children and adolescents with syncope; predictor of syncope recurrence.
Kouakam C, Vaksmann G, Pachy E, Lacroix D, Rey C, Kacet S
Eur Heart J 2001 Sep;22(17):1618-25. doi: 10.1053/euhj.2000.2577. PMID: 11492992
Inadequate sympathovagal balance in response to orthostatism in patients with unexplained syncope and a positive head up tilt test.
Kouakam C, Lacroix D, Zghal N, Logier R, Klug D, Le Franc P, Jarwe M, Kacet S
Heart 1999 Sep;82(3):312-8. doi: 10.1136/hrt.82.3.312. PMID: 10455081Free PMC Article
Psychogenic syncope diagnosed by prolonged head-up tilt testing.
Petersen ME, Williams TR, Sutton R
QJM 1995 Mar;88(3):209-13. PMID: 7767671

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