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Psychogenic syncope

MedGen UID:
536371
•Concept ID:
C0235245
•
Mental or Behavioral Dysfunction
Synonyms: psychogenic syncope; syncope, psychogenic
SNOMED CT: Psychogenic syncope (386572005)

Definition

A condition in which syncope occurs due to a conversion disorder. (ACC-AHA) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPsychogenic syncope

Professional guidelines

PubMed

Utility of serum lactate on differential diagnosis of seizure-like activity: A systematic review and meta-analysis.
Patel J, Tran QK, Martinez S, Wright H, Pourmand A
Seizure 2022 Nov;102:134-142. Epub 2022 Oct 7 doi: 10.1016/j.seizure.2022.10.007. PMID: 36242832
Diagnostic criteria to aid the differential diagnosis of patients presenting with transient loss of consciousness: A systematic review.
Wardrope A, Newberry E, Reuber M
Seizure 2018 Oct;61:139-148. Epub 2018 Aug 16 doi: 10.1016/j.seizure.2018.08.012. PMID: 30145472
Psychogenic pseudosyncope: diagnosis and management.
Raj V, Rowe AA, Fleisch SB, Paranjape SY, Arain AM, Nicolson SE
Auton Neurosci 2014 Sep;184:66-72. Epub 2014 May 16 doi: 10.1016/j.autneu.2014.05.003. PMID: 24882462

Recent clinical studies

Etiology

Near-infrared Spectroscopy to Assess Cerebral Perfusion during Head-up Tilt-table Test in Patients with Syncope.
Ayers MD, Lawrence DK
Congenit Heart Dis 2015 Jul-Aug;10(4):333-9. Epub 2014 Nov 24 doi: 10.1111/chd.12236. PMID: 25421641
Unexplained syncopes: what place is there for the liaison psychiatry? Analysis of the first year of the Interdisciplinary Centre of Unexplained Faintness and Syncopes.
Jacques D, Blommaert D, Gilain C, Zdanowicz N, Ossemann M
Psychiatr Danub 2012 Sep;24 Suppl 1:S21-4. PMID: 22945181
Predictive models of syncope causes in an outpatient clinic.
Graf D, Schlaepfer J, Gollut E, van Melle G, Mischler C, Fromer M, Kappenberger L, Pruvot E
Int J Cardiol 2008 Jan 24;123(3):249-56. Epub 2007 Mar 29 doi: 10.1016/j.ijcard.2006.12.007. PMID: 17397948
Long-term follow-up of children and adolescents with syncope; predictor of syncope recurrence.
Kouakam C, Vaksmann G, Pachy E, Lacroix D, Rey C, Kacet S
Eur Heart J 2001 Sep;22(17):1618-25. doi: 10.1053/euhj.2000.2577. PMID: 11492992
Inadequate sympathovagal balance in response to orthostatism in patients with unexplained syncope and a positive head up tilt test.
Kouakam C, Lacroix D, Zghal N, Logier R, Klug D, Le Franc P, Jarwe M, Kacet S
Heart 1999 Sep;82(3):312-8. doi: 10.1136/hrt.82.3.312. PMID: 10455081Free PMC Article

Diagnosis

Devil is in the detail.
Jacob JR, Paul A, Alex AG
BMJ Case Rep 2018 Apr 17;2018 doi: 10.1136/bcr-2017-224134. PMID: 29666096Free PMC Article
Psychogenic syncope? A cautionary note.
Kanjwal K, Kanjwal Y, Karabin B, Grubb BP
Pacing Clin Electrophysiol 2009 Jul;32(7):862-5. doi: 10.1111/j.1540-8159.2009.02400.x. PMID: 19572860
Stepwise evaluation of unexplained syncope in a large ambulatory population.
Iglesias JF, Graf D, Forclaz A, Schlaepfer J, Fromer M, Pruvot E
Pacing Clin Electrophysiol 2009 Mar;32 Suppl 1:S202-6. doi: 10.1111/j.1540-8159.2008.02291.x. PMID: 19250095
Long-term follow-up of children and adolescents with syncope; predictor of syncope recurrence.
Kouakam C, Vaksmann G, Pachy E, Lacroix D, Rey C, Kacet S
Eur Heart J 2001 Sep;22(17):1618-25. doi: 10.1053/euhj.2000.2577. PMID: 11492992
Syncope and seizures of psychogenic origin: identification with head-upright tilt table testing.
Grubb BP, Gerard G, Wolfe DA, Samoil D, Davenport CW, Homan RW, Temesy-Armos P
Clin Cardiol 1992 Nov;15(11):839-42. doi: 10.1002/clc.4960151109. PMID: 10969628

Therapy

Devil is in the detail.
Jacob JR, Paul A, Alex AG
BMJ Case Rep 2018 Apr 17;2018 doi: 10.1136/bcr-2017-224134. PMID: 29666096Free PMC Article
Hypoglycemia as a possible factor in the induction of vasovagal syncope.
Salins PC, Kuriakose M, Sharma SM, Tauro DP
Oral Surg Oral Med Oral Pathol 1992 Nov;74(5):544-9. doi: 10.1016/0030-4220(92)90340-v. PMID: 1437055

Prognosis

Near-infrared Spectroscopy to Assess Cerebral Perfusion during Head-up Tilt-table Test in Patients with Syncope.
Ayers MD, Lawrence DK
Congenit Heart Dis 2015 Jul-Aug;10(4):333-9. Epub 2014 Nov 24 doi: 10.1111/chd.12236. PMID: 25421641
Stepwise evaluation of unexplained syncope in a large ambulatory population.
Iglesias JF, Graf D, Forclaz A, Schlaepfer J, Fromer M, Pruvot E
Pacing Clin Electrophysiol 2009 Mar;32 Suppl 1:S202-6. doi: 10.1111/j.1540-8159.2008.02291.x. PMID: 19250095
Predictive models of syncope causes in an outpatient clinic.
Graf D, Schlaepfer J, Gollut E, van Melle G, Mischler C, Fromer M, Kappenberger L, Pruvot E
Int J Cardiol 2008 Jan 24;123(3):249-56. Epub 2007 Mar 29 doi: 10.1016/j.ijcard.2006.12.007. PMID: 17397948
Long-term follow-up of children and adolescents with syncope; predictor of syncope recurrence.
Kouakam C, Vaksmann G, Pachy E, Lacroix D, Rey C, Kacet S
Eur Heart J 2001 Sep;22(17):1618-25. doi: 10.1053/euhj.2000.2577. PMID: 11492992
Inadequate sympathovagal balance in response to orthostatism in patients with unexplained syncope and a positive head up tilt test.
Kouakam C, Lacroix D, Zghal N, Logier R, Klug D, Le Franc P, Jarwe M, Kacet S
Heart 1999 Sep;82(3):312-8. doi: 10.1136/hrt.82.3.312. PMID: 10455081Free PMC Article

Clinical prediction guides

Near-infrared Spectroscopy to Assess Cerebral Perfusion during Head-up Tilt-table Test in Patients with Syncope.
Ayers MD, Lawrence DK
Congenit Heart Dis 2015 Jul-Aug;10(4):333-9. Epub 2014 Nov 24 doi: 10.1111/chd.12236. PMID: 25421641
Predictive models of syncope causes in an outpatient clinic.
Graf D, Schlaepfer J, Gollut E, van Melle G, Mischler C, Fromer M, Kappenberger L, Pruvot E
Int J Cardiol 2008 Jan 24;123(3):249-56. Epub 2007 Mar 29 doi: 10.1016/j.ijcard.2006.12.007. PMID: 17397948
Long-term follow-up of children and adolescents with syncope; predictor of syncope recurrence.
Kouakam C, Vaksmann G, Pachy E, Lacroix D, Rey C, Kacet S
Eur Heart J 2001 Sep;22(17):1618-25. doi: 10.1053/euhj.2000.2577. PMID: 11492992
Inadequate sympathovagal balance in response to orthostatism in patients with unexplained syncope and a positive head up tilt test.
Kouakam C, Lacroix D, Zghal N, Logier R, Klug D, Le Franc P, Jarwe M, Kacet S
Heart 1999 Sep;82(3):312-8. doi: 10.1136/hrt.82.3.312. PMID: 10455081Free PMC Article
Psychogenic syncope diagnosed by prolonged head-up tilt testing.
Petersen ME, Williams TR, Sutton R
QJM 1995 Mar;88(3):209-13. PMID: 7767671

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