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Sickle cell nephropathy

MedGen UID:
536792
Concept ID:
C0238305
Disease or Syndrome
Synonym: Sickle Cell Nephropathy
SNOMED CT: Sickle cell nephropathy (13886001)

Definition

Nephropathy secondary to sickle cell disease, characterized by the presence of sickled erythrocytes in the renal medullary vessels, renal ischemia and microinfarctions, renal papillary necrosis, and renal tubular abnormalities. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Hariri E, Mansour A, El Alam A, Daaboul Y, Korjian S, Aoun Bahous S
Int Urol Nephrol 2018 Jun;50(6):1075-1083. Epub 2018 Jan 30 doi: 10.1007/s11255-018-1803-3. PMID: 29383580
da Silva GB Jr, Libório AB, Daher Ede F
Ann Hematol 2011 Dec;90(12):1371-9. Epub 2011 Sep 8 doi: 10.1007/s00277-011-1327-8. PMID: 21901339
McKie KT, Hanevold CD, Hernandez C, Waller JL, Ortiz L, McKie KM
J Pediatr Hematol Oncol 2007 Mar;29(3):140-4. doi: 10.1097/MPH.0b013e3180335081. PMID: 17356390

Recent clinical studies

Etiology

Amarapurkar P, Roberts L, Navarrete J, El Rassi F
Adv Chronic Kidney Dis 2022 Mar;29(2):141-148.e1. doi: 10.1053/j.ackd.2022.03.004. PMID: 35817521
Belisário AR, da Silva AA, Silva CV, de Souza LM, Wakabayashi EA, Araújo SA, Simoes-E-Silva AC
Biomark Med 2019 Aug;13(11):967-987. Epub 2019 Aug 8 doi: 10.2217/bmm-2019-0105. PMID: 31390894
Olaniran KO, Eneanya ND, Nigwekar SU, Vela-Parada XF, Achebe MM, Sharma A, Thadhani RI
Blood Purif 2019;47(1-3):205-213. Epub 2018 Dec 5 doi: 10.1159/000494581. PMID: 30517931
Airy M, Eknoyan G
Clin Nephrol 2017 Feb;87 (2017)(2):55-68. doi: 10.5414/CN108991. PMID: 27900941
Nath KA, Hebbel RP
Nat Rev Nephrol 2015 Mar;11(3):161-71. Epub 2015 Feb 10 doi: 10.1038/nrneph.2015.8. PMID: 25668001Free PMC Article

Diagnosis

Adebayo OC, Van den Heuvel LP, Olowu WA, Levtchenko EN, Labarque V
Pediatr Nephrol 2022 Jun;37(6):1231-1243. Epub 2021 May 29 doi: 10.1007/s00467-021-05126-4. PMID: 34050806
Elliott A, Bruner E
Arch Pathol Lab Med 2019 Dec;143(12):1556-1561. Epub 2019 Mar 11 doi: 10.5858/arpa.2017-0492-RS. PMID: 30855171
Olaniran KO, Eneanya ND, Nigwekar SU, Vela-Parada XF, Achebe MM, Sharma A, Thadhani RI
Blood Purif 2019;47(1-3):205-213. Epub 2018 Dec 5 doi: 10.1159/000494581. PMID: 30517931
Hariri E, Mansour A, El Alam A, Daaboul Y, Korjian S, Aoun Bahous S
Int Urol Nephrol 2018 Jun;50(6):1075-1083. Epub 2018 Jan 30 doi: 10.1007/s11255-018-1803-3. PMID: 29383580
Gargiulo R, Pandya M, Seba A, Haddad RY, Lerma EV
Dis Mon 2014 Oct;60(10):494-9. Epub 2014 Oct 3 doi: 10.1016/j.disamonth.2014.08.004. PMID: 25282510

Therapy

Amarapurkar P, Roberts L, Navarrete J, El Rassi F
Adv Chronic Kidney Dis 2022 Mar;29(2):141-148.e1. doi: 10.1053/j.ackd.2022.03.004. PMID: 35817521
Payán-Pernía S, Ruiz Llobet A, Remacha Sevilla ÁF, Egido J, Ballarín Castán JA, Moreno JA
Nefrologia (Engl Ed) 2021 Jul-Aug;41(4):373-382. Epub 2021 Oct 27 doi: 10.1016/j.nefroe.2021.10.001. PMID: 36165106
Olaniran KO, Eneanya ND, Nigwekar SU, Vela-Parada XF, Achebe MM, Sharma A, Thadhani RI
Blood Purif 2019;47(1-3):205-213. Epub 2018 Dec 5 doi: 10.1159/000494581. PMID: 30517931
Hariri E, Mansour A, El Alam A, Daaboul Y, Korjian S, Aoun Bahous S
Int Urol Nephrol 2018 Jun;50(6):1075-1083. Epub 2018 Jan 30 doi: 10.1007/s11255-018-1803-3. PMID: 29383580
Buckalew VM Jr
Ann Intern Med 1970 Sep;73(3):488-9. doi: 10.7326/0003-4819-73-3-488. PMID: 5456001

Prognosis

Maurício L, Ribeiro S, Santos L, Miranda DB
Rev Assoc Med Bras (1992) 2021 Feb;67(2):313-317. doi: 10.1590/1806-9282.67.02.20200676. PMID: 34406259
Gargiulo R, Pandya M, Seba A, Haddad RY, Lerma EV
Dis Mon 2014 Oct;60(10):494-9. Epub 2014 Oct 3 doi: 10.1016/j.disamonth.2014.08.004. PMID: 25282510
Alhwiesh A
Saudi J Kidney Dis Transpl 2014 Mar;25(2):249-65. doi: 10.4103/1319-2442.128495. PMID: 24625990
Sharpe CC, Thein SL
Br J Haematol 2011 Nov;155(3):287-97. Epub 2011 Sep 9 doi: 10.1111/j.1365-2141.2011.08853.x. PMID: 21902687
Scheinman JI
Nat Clin Pract Nephrol 2009 Feb;5(2):78-88. Epub 2008 Dec 2 doi: 10.1038/ncpneph1008. PMID: 19048000

Clinical prediction guides

Ndour EHM, Mnika K, Tall FG, Seck M, Ly ID, Nembaware V, Mazandu GK, Sagna Bassène HAT, Dione R, Ndongo AA, Diop JPD, Barry NOK, Djité M, Ndiaye Diallo R, Guèye PM, Diop S, Diagne I, Cissé A, Wonkam A, Lopez Sall P
PLoS One 2022;17(11):e0273745. Epub 2022 Nov 21 doi: 10.1371/journal.pone.0273745. PMID: 36409722Free PMC Article
Maurício L, Ribeiro S, Santos L, Miranda DB
Rev Assoc Med Bras (1992) 2021 Feb;67(2):313-317. doi: 10.1590/1806-9282.67.02.20200676. PMID: 34406259
Belisário AR, da Silva AA, Silva CV, de Souza LM, Wakabayashi EA, Araújo SA, Simoes-E-Silva AC
Biomark Med 2019 Aug;13(11):967-987. Epub 2019 Aug 8 doi: 10.2217/bmm-2019-0105. PMID: 31390894
Elliott A, Bruner E
Arch Pathol Lab Med 2019 Dec;143(12):1556-1561. Epub 2019 Mar 11 doi: 10.5858/arpa.2017-0492-RS. PMID: 30855171
Scheinman JI
Nat Clin Pract Nephrol 2009 Feb;5(2):78-88. Epub 2008 Dec 2 doi: 10.1038/ncpneph1008. PMID: 19048000

Recent systematic reviews

Roy NB, Carpenter A, Dale-Harris I, Dorée C, Estcourt LJ
Cochrane Database Syst Rev 2023 Aug 4;8(8):CD012380. doi: 10.1002/14651858.CD012380.pub3. PMID: 37539955Free PMC Article
Maurício L, Ribeiro S, Santos L, Miranda DB
Rev Assoc Med Bras (1992) 2021 Feb;67(2):313-317. doi: 10.1590/1806-9282.67.02.20200676. PMID: 34406259
Almasri J, Tello M, Benkhadra R, Morrow AS, Hasan B, Farah W, Alvarez Villalobos N, Mohammed K, Allen JP, Prokop LJ, Wang Z, Kasiske BL, Israni AK, Murad MH
Transplantation 2019 Dec;103(12):2591-2601. doi: 10.1097/TP.0000000000002652. PMID: 30768569
Roy NB, Fortin PM, Bull KR, Doree C, Trivella M, Hopewell S, Estcourt LJ
Cochrane Database Syst Rev 2017 Jul 3;7(7):CD012380. doi: 10.1002/14651858.CD012380.pub2. PMID: 28672087Free PMC Article

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