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hypoplasia

MedGen UID:
537146
Concept ID:
C0243069
Pathologic Function
Synonyms: Hypocellularity; Hypoplasia
SNOMED CT: Hypoplasia (55199003); Hypocellularity (55199003)

Definition

Incomplete or underdevelopment of a tissue or organ. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVhypoplasia

Professional guidelines

PubMed

Marszałek-Kruk BA, Wójcicki P, Dowgierd K, Śmigiel R
Genes (Basel) 2021 Sep 9;12(9) doi: 10.3390/genes12091392. PMID: 34573374Free PMC Article
Passos IMPE, Britto RL
Taiwan J Obstet Gynecol 2020 Mar;59(2):183-188. doi: 10.1016/j.tjog.2020.01.003. PMID: 32127135
Kosiński P, Wielgoś M
Ginekol Pol 2017;88(1):24-30. doi: 10.5603/GP.a2017.0005. PMID: 28157247

Recent clinical studies

Etiology

Landsend ECS, Lagali N, Utheim TP
Surv Ophthalmol 2021 Nov-Dec;66(6):1031-1050. Epub 2021 Mar 4 doi: 10.1016/j.survophthal.2021.02.011. PMID: 33675823
Zanni G, Bertini E
Handb Clin Neurol 2018;155:175-189. doi: 10.1016/B978-0-444-64189-2.00011-1. PMID: 29891057
Bardellini E, Amadori F, Pasini S, Majorana A
J Clin Pediatr Dent 2017;41(1):5-9. doi: 10.17796/1053-4628-41.1.5. PMID: 28052204
Seow WK
Aust Dent J 2014 Jun;59 Suppl 1:143-54. Epub 2013 Oct 27 doi: 10.1111/adj.12104. PMID: 24164394
Salanitri S, Seow WK
Aust Dent J 2013 Jun;58(2):133-40; quiz 266. Epub 2013 May 5 doi: 10.1111/adj.12039. PMID: 23713631

Diagnosis

Sataite I, Cudlip S, Jayamohan J, Ganau M
Handb Clin Neurol 2021;181:51-64. doi: 10.1016/B978-0-12-820683-6.00005-1. PMID: 34238479
Accogli A, Addour-Boudrahem N, Srour M
Cerebellum 2021 Aug;20(4):631-658. Epub 2021 Feb 3 doi: 10.1007/s12311-020-01224-5. PMID: 33534089
Lerman-Sagie T, Prayer D, Stöcklein S, Malinger G
Handb Clin Neurol 2018;155:3-23. doi: 10.1016/B978-0-444-64189-2.00001-9. PMID: 29891067
Rao MH, Aluru SC, Jayam C, Bandlapalli A, Patel N
J Contemp Dent Pract 2016 Jul 1;17(7):609-13. PMID: 27595731
Seow WK
Aust Dent J 2014 Jun;59 Suppl 1:143-54. Epub 2013 Oct 27 doi: 10.1111/adj.12104. PMID: 24164394

Therapy

Uzel I, Gurlek C, Kuter B, Ertugrul F, Eden E
Biomed Res Int 2022;2022:7205692. Epub 2022 Jun 20 doi: 10.1155/2022/7205692. PMID: 35769675Free PMC Article
Ballikaya E, Ünverdi GE, Cehreli ZC
Clin Oral Investig 2022 Feb;26(2):2197-2205. Epub 2021 Nov 6 doi: 10.1007/s00784-021-04236-5. PMID: 34743243Free PMC Article
Deprest JA, Nicolaides KH, Benachi A, Gratacos E, Ryan G, Persico N, Sago H, Johnson A, Wielgoś M, Berg C, Van Calster B, Russo FM; TOTAL Trial for Severe Hypoplasia Investigators
N Engl J Med 2021 Jul 8;385(2):107-118. Epub 2021 Jun 8 doi: 10.1056/NEJMoa2027030. PMID: 34106556Free PMC Article
Deprest JA, Benachi A, Gratacos E, Nicolaides KH, Berg C, Persico N, Belfort M, Gardener GJ, Ville Y, Johnson A, Morini F, Wielgoś M, Van Calster B, DeKoninck PLJ; TOTAL Trial for Moderate Hypoplasia Investigators
N Engl J Med 2021 Jul 8;385(2):119-129. Epub 2021 Jun 8 doi: 10.1056/NEJMoa2026983. PMID: 34106555Free PMC Article
Chandrasekharan P, Lakshminrusimha S, Abman SH
Semin Fetal Neonatal Med 2021 Apr;26(2):101200. Epub 2021 Jan 22 doi: 10.1016/j.siny.2021.101200. PMID: 33509680

Prognosis

Kays DW
Semin Pediatr Surg 2017 Jun;26(3):166-170. Epub 2017 Apr 25 doi: 10.1053/j.sempedsurg.2017.04.006. PMID: 28641755
Leeuwen L, Fitzgerald DA
J Paediatr Child Health 2014 Sep;50(9):667-73. Epub 2014 Feb 17 doi: 10.1111/jpc.12508. PMID: 24528549
Steinkuller PG, Du L, Gilbert C, Foster A, Collins ML, Coats DK
J AAPOS 1999 Feb;3(1):26-32. doi: 10.1016/s1091-8531(99)70091-1. PMID: 10071898
Peipert JF, Donnenfeld AE
Obstet Gynecol Surv 1991 Jun;46(6):325-39. doi: 10.1097/00006254-199106000-00002. PMID: 2067755
Miura T
Plast Reconstr Surg 1982 Mar;69(3):470-81. doi: 10.1097/00006534-198203000-00012. PMID: 7063570

Clinical prediction guides

Ripoll T, Solla F, Oborocianu I, Bertoncelli C, Rampal V
Orthop Traumatol Surg Res 2023 May;109(3):103316. Epub 2022 May 13 doi: 10.1016/j.otsr.2022.103316. PMID: 35569755
Chatterjee D, Ing RJ, Gien J
Anesth Analg 2020 Sep;131(3):808-821. doi: 10.1213/ANE.0000000000004324. PMID: 31335403
Triebwasser JE, Treadwell MC
Semin Fetal Neonatal Med 2017 Aug;22(4):245-249. Epub 2017 Mar 18 doi: 10.1016/j.siny.2017.03.001. PMID: 28325581
Aulbert W, Kemper MJ
Pediatr Nephrol 2016 Apr;31(4):563-74. Epub 2015 Jun 17 doi: 10.1007/s00467-015-3140-4. PMID: 26081158
Vergani P
Curr Opin Obstet Gynecol 2012 Mar;24(2):89-94. doi: 10.1097/GCO.0b013e3283505a86. PMID: 22249145

Recent systematic reviews

Lopes LB, Machado V, Mascarenhas P, Mendes JJ, Botelho J
Sci Rep 2021 Nov 17;11(1):22405. doi: 10.1038/s41598-021-01541-7. PMID: 34789780Free PMC Article
Freitas DA, Souza-Santos R, Carvalho LMA, Barros WB, Neves LM, Brasil P, Wakimoto MD
PLoS One 2020;15(12):e0242367. Epub 2020 Dec 15 doi: 10.1371/journal.pone.0242367. PMID: 33320867Free PMC Article
da Cunha Coelho ASE, Mata PCM, Lino CA, Macho VMP, Areias CMFGP, Norton APMAP, Augusto APCM
J Esthet Restor Dent 2019 Jan;31(1):26-39. Epub 2018 Oct 4 doi: 10.1111/jerd.12420. PMID: 30284749
Elhennawy K, Schwendicke F
J Dent 2016 Dec;55:16-24. Epub 2016 Sep 28 doi: 10.1016/j.jdent.2016.09.012. PMID: 27693779
Silva MJ, Scurrah KJ, Craig JM, Manton DJ, Kilpatrick N
Community Dent Oral Epidemiol 2016 Aug;44(4):342-53. Epub 2016 Apr 28 doi: 10.1111/cdoe.12229. PMID: 27121068

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