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Abnormal Eustachian tube morphology

MedGen UID:
537429
•Concept ID:
C0262475
•
Congenital Abnormality; Finding
Synonyms: Abnormality of the Eustachian tube; Patent tuba eustachii
SNOMED CT: Congenital abnormality of Eustachian tube (204250005); Eustachian tube anomalies (204250005)
 
HPO: HP:0040115

Definition

A structural anomaly of the Eustachian tube (ET). The ET is a biomechanical valve between the nasopharynx and the middle ear. Physiologically, it controls the passive adaptation of the middle ear air pressure to the ambient air pressure primarily via direct muscular actions of the soft palate. In the closed state it protects the middle ear. Inadequate function of the ET causes middle ear ventilation disorders. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal Eustachian tube morphology

Professional guidelines

PubMed

Assessment and management of retraction pockets.
Alper C, Olszewska E
Otolaryngol Pol 2017 Feb 28;71(1):1-21. doi: 10.5604/01.3001.0009.5547. PMID: 28485292
Cleft Lip Repair, Nasoalveolar Molding, and Primary Cleft Rhinoplasty.
Bhuskute AA, Tollefson TT
Facial Plast Surg Clin North Am 2016 Nov;24(4):453-466. doi: 10.1016/j.fsc.2016.06.015. PMID: 27712813
Management of patulous eustachian tube with habitual sniffing.
Ikeda R, Oshima T, Oshima H, Miyazaki M, Kikuchi T, Kawase T, Kobayashi T
Otol Neurotol 2011 Jul;32(5):790-3. doi: 10.1097/MAO.0b013e3182184e23. PMID: 21659936

Recent clinical studies

Etiology

Paper patching for patulous eustachian tube.
Kim SJ, Shin SA, Lee HY, Park YH
Acta Otolaryngol 2019 Feb;139(2):122-128. Epub 2019 Feb 14 doi: 10.1080/00016489.2018.1541505. PMID: 30762451
Otologic disorders in Turner syndrome.
Bois E, Nassar M, Zenaty D, Léger J, Van Den Abbeele T, Teissier N
Eur Ann Otorhinolaryngol Head Neck Dis 2018 Feb;135(1):21-24. Epub 2017 Sep 21 doi: 10.1016/j.anorl.2017.08.006. PMID: 28941966
Otologic manifestations of Larsen syndrome.
Marques LHS, Martins DV, Juares GL, Lorenzetti FTM, Monsanto RDC
Int J Pediatr Otorhinolaryngol 2017 Oct;101:223-229. Epub 2017 Aug 22 doi: 10.1016/j.ijporl.2017.08.020. PMID: 28964299
Otitis media.
Schilder AG, Chonmaitree T, Cripps AW, Rosenfeld RM, Casselbrant ML, Haggard MP, Venekamp RP
Nat Rev Dis Primers 2016 Sep 8;2(1):16063. doi: 10.1038/nrdp.2016.63. PMID: 27604644Free PMC Article
Otitis media and eustachian tube dysfunction: connection to allergic rhinitis.
Fireman P
J Allergy Clin Immunol 1997 Feb;99(2):S787-97. doi: 10.1016/s0091-6749(97)70130-1. PMID: 9042072

Diagnosis

Eagle syndrome: toward a clinical delimitation.
González-García N, Porta-Etessam J, García-Azorín D
Neurologia (Engl Ed) 2021 Jul-Aug;36(6):412-417. Epub 2020 Feb 13 doi: 10.1016/j.nrleng.2018.03.007. PMID: 34238523
Paper patching for patulous eustachian tube.
Kim SJ, Shin SA, Lee HY, Park YH
Acta Otolaryngol 2019 Feb;139(2):122-128. Epub 2019 Feb 14 doi: 10.1080/00016489.2018.1541505. PMID: 30762451
Assessment of Eustachian tube function in patients with tympanic membrane retraction and in normal subjects.
Canali I, Petersen Schmidt Rosito L, Siliprandi B, Giugno C, Selaimen da Costa S
Braz J Otorhinolaryngol 2017 Jan-Feb;83(1):50-58. Epub 2016 Apr 25 doi: 10.1016/j.bjorl.2016.01.010. PMID: 27174771Free PMC Article
Otitis media.
Schilder AG, Chonmaitree T, Cripps AW, Rosenfeld RM, Casselbrant ML, Haggard MP, Venekamp RP
Nat Rev Dis Primers 2016 Sep 8;2(1):16063. doi: 10.1038/nrdp.2016.63. PMID: 27604644Free PMC Article
Anatomy and physiology of the velopharyngeal mechanism.
Perry JL
Semin Speech Lang 2011 May;32(2):83-92. Epub 2011 Sep 26 doi: 10.1055/s-0031-1277712. PMID: 21948636

Therapy

Relevance of cleft palatal width in short-term otologic outcomes.
Martin HL, Poehlein ER, Allori AC, Marcus JR, Cheng J, Lee H, Raynor EM
Int J Pediatr Otorhinolaryngol 2023 Aug;171:111647. Epub 2023 Jul 6 doi: 10.1016/j.ijporl.2023.111647. PMID: 37429111
Otologic manifestations of Larsen syndrome.
Marques LHS, Martins DV, Juares GL, Lorenzetti FTM, Monsanto RDC
Int J Pediatr Otorhinolaryngol 2017 Oct;101:223-229. Epub 2017 Aug 22 doi: 10.1016/j.ijporl.2017.08.020. PMID: 28964299
Otitis media.
Schilder AG, Chonmaitree T, Cripps AW, Rosenfeld RM, Casselbrant ML, Haggard MP, Venekamp RP
Nat Rev Dis Primers 2016 Sep 8;2(1):16063. doi: 10.1038/nrdp.2016.63. PMID: 27604644Free PMC Article
The immediate effect of adenotonsillectomy on Eustachian tube function in children.
Choi JH, Yoon HC, Kim TM, Choi J, Park IH, Kim TH, Lee HM, Lee SH, Lee SH
Int J Pediatr Otorhinolaryngol 2015 Sep;79(9):1444-7. Epub 2015 Jun 28 doi: 10.1016/j.ijporl.2015.06.025. PMID: 26169069
Otitis media with effusion in childhood.
Marshall SG, Bierman CW, Shapiro GG
Ann Allergy 1984 Nov;53(5):370-8, 394. PMID: 6149711

Prognosis

Relevance of cleft palatal width in short-term otologic outcomes.
Martin HL, Poehlein ER, Allori AC, Marcus JR, Cheng J, Lee H, Raynor EM
Int J Pediatr Otorhinolaryngol 2023 Aug;171:111647. Epub 2023 Jul 6 doi: 10.1016/j.ijporl.2023.111647. PMID: 37429111
Paper patching for patulous eustachian tube.
Kim SJ, Shin SA, Lee HY, Park YH
Acta Otolaryngol 2019 Feb;139(2):122-128. Epub 2019 Feb 14 doi: 10.1080/00016489.2018.1541505. PMID: 30762451
Association between symptomatic submucous cleft palate and otologic disease: A retrospective review.
Kwinter A, Dworschak-Stokan A, Paradis J, Husein M
Int J Pediatr Otorhinolaryngol 2018 Dec;115:77-81. Epub 2018 Sep 22 doi: 10.1016/j.ijporl.2018.09.022. PMID: 30368399
Should Nasal Function be Considered Prior to Tympanoplasty?
Akyıldız MY, Özmen ÖA, Demir UL, Kasapoğlu F, Coşkun HH, Basut Oİ, Sığırlı D
J Int Adv Otol 2018 Apr;14(1):53-57. Epub 2017 Nov 21 doi: 10.5152/iao.2017.3624. PMID: 29165311Free PMC Article
The submucous cleft palate: diagnosis and therapy.
Reiter R, Brosch S, Wefel H, Schlömer G, Haase S
Int J Pediatr Otorhinolaryngol 2011 Jan;75(1):85-8. Epub 2010 Nov 26 doi: 10.1016/j.ijporl.2010.10.015. PMID: 21112097

Clinical prediction guides

Association between symptomatic submucous cleft palate and otologic disease: A retrospective review.
Kwinter A, Dworschak-Stokan A, Paradis J, Husein M
Int J Pediatr Otorhinolaryngol 2018 Dec;115:77-81. Epub 2018 Sep 22 doi: 10.1016/j.ijporl.2018.09.022. PMID: 30368399
Should Nasal Function be Considered Prior to Tympanoplasty?
Akyıldız MY, Özmen ÖA, Demir UL, Kasapoğlu F, Coşkun HH, Basut Oİ, Sığırlı D
J Int Adv Otol 2018 Apr;14(1):53-57. Epub 2017 Nov 21 doi: 10.5152/iao.2017.3624. PMID: 29165311Free PMC Article
Eustachian Tube Dysfunction-Related Symptoms in Chronic Nasal Obstruction Caused by Inferior Turbinate Enlargement.
Harju T, Kivekäs I, Numminen J, Rautiainen M
Ann Otol Rhinol Laryngol 2017 Dec;126(12):798-803. Epub 2017 Oct 4 doi: 10.1177/0003489417735538. PMID: 28975810
Assessment of Eustachian tube function in patients with tympanic membrane retraction and in normal subjects.
Canali I, Petersen Schmidt Rosito L, Siliprandi B, Giugno C, Selaimen da Costa S
Braz J Otorhinolaryngol 2017 Jan-Feb;83(1):50-58. Epub 2016 Apr 25 doi: 10.1016/j.bjorl.2016.01.010. PMID: 27174771Free PMC Article
Endoscopy of the eustachian tube: use of the fiberscope and the telescope.
Conticello S, Saita V, La Mantia I, Ferlito S
Arch Otorhinolaryngol 1989;246(5):256-8. doi: 10.1007/BF00463567. PMID: 2590028

Recent systematic reviews

Otologic manifestations of Larsen syndrome.
Marques LHS, Martins DV, Juares GL, Lorenzetti FTM, Monsanto RDC
Int J Pediatr Otorhinolaryngol 2017 Oct;101:223-229. Epub 2017 Aug 22 doi: 10.1016/j.ijporl.2017.08.020. PMID: 28964299

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