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Telogen effluvium

MedGen UID:
537938
•Concept ID:
C0263518
•
Disease or Syndrome
Synonyms: Telogen Effluvium; telogen effluvium
SNOMED CT: Telogen effluvium (39479004)
 
HPO: HP:0025470
Monarch Initiative: MONDO:0002153

Definition

A type of hair loss characterized by an abnormal increase in dormant, telogen stage hair follicles. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTelogen effluvium

Professional guidelines

PubMed

Oral minoxidil treatment for hair loss: A review of efficacy and safety.
Randolph M, Tosti A
J Am Acad Dermatol 2021 Mar;84(3):737-746. Epub 2020 Jul 2 doi: 10.1016/j.jaad.2020.06.1009. PMID: 32622136
Hair Loss: Common Causes and Treatment.
Phillips TG, Slomiany WP, Allison R
Am Fam Physician 2017 Sep 15;96(6):371-378. PMID: 28925637
The diagnosis and treatment of iron deficiency and its potential relationship to hair loss.
Trost LB, Bergfeld WF, Calogeras E
J Am Acad Dermatol 2006 May;54(5):824-44. doi: 10.1016/j.jaad.2005.11.1104. PMID: 16635664

Recent clinical studies

Etiology

Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study.
Milani M, Colombo F; GFM-O-Trial Investigators Group: Chiara Baraldo (Padova), Mauro Barbareschi (Milano), Paolo Chieco (Ruvo di Puglia), Laura Colonna (Roma), Mandel Victor Desmond (Modena), Maria Cristina Fiorucci (Genova)
Skin Res Technol 2023 Jun;29(6):e13381. doi: 10.1111/srt.13381. PMID: 37357646Free PMC Article
Oral minoxidil use in androgenetic alopecia and telogen effluvium.
Feaster B, Onamusi T, Cooley JE, McMichael AJ
Arch Dermatol Res 2023 Mar;315(2):201-205. Epub 2022 Mar 4 doi: 10.1007/s00403-022-02331-5. PMID: 35244759
A proprietary herbal extract against hair loss in androgenetic alopecia and telogen effluvium: a placebo-controlled, single-blind, clinical-instrumental study.
Pekmezci E, Dündar C, Türkoğlu M
Acta Dermatovenerol Alp Pannonica Adriat 2018 Jun;27(2):51-57. PMID: 29945259
Psoriatic alopecia.
George SM, Taylor MR, Farrant PB
Clin Exp Dermatol 2015 Oct;40(7):717-21. Epub 2015 Jul 23 doi: 10.1111/ced.12715. PMID: 26202646
The diagnosis and treatment of iron deficiency and its potential relationship to hair loss.
Trost LB, Bergfeld WF, Calogeras E
J Am Acad Dermatol 2006 May;54(5):824-44. doi: 10.1016/j.jaad.2005.11.1104. PMID: 16635664

Diagnosis

Common causes of hair loss - clinical manifestations, trichoscopy and therapy.
Alessandrini A, Bruni F, Piraccini BM, Starace M
J Eur Acad Dermatol Venereol 2021 Mar;35(3):629-640. Epub 2021 Jan 8 doi: 10.1111/jdv.17079. PMID: 33290611
Hair Loss: Common Causes and Treatment.
Phillips TG, Slomiany WP, Allison R
Am Fam Physician 2017 Sep 15;96(6):371-378. PMID: 28925637
Evaluation and diagnosis of the hair loss patient: part I. History and clinical examination.
Mubki T, Rudnicka L, Olszewska M, Shapiro J
J Am Acad Dermatol 2014 Sep;71(3):415.e1-415.e15. doi: 10.1016/j.jaad.2014.04.070. PMID: 25128118
Histopathology of alopecia: a clinicopathological approach to diagnosis.
Stefanato CM
Histopathology 2010 Jan;56(1):24-38. doi: 10.1111/j.1365-2559.2009.03439.x. PMID: 20055903
Diagnosing and treating hair loss.
Mounsey AL, Reed SW
Am Fam Physician 2009 Aug 15;80(4):356-62. PMID: 19678603

Therapy

Role of nutritional supplements in selected dermatological disorders: A review.
Sardana K, Sachdeva S
J Cosmet Dermatol 2022 Jan;21(1):85-98. Epub 2021 Sep 26 doi: 10.1111/jocd.14436. PMID: 34564936
Minoxidil: a comprehensive review.
Gupta AK, Talukder M, Venkataraman M, Bamimore MA
J Dermatolog Treat 2022 Jun;33(4):1896-1906. Epub 2021 Jul 20 doi: 10.1080/09546634.2021.1945527. PMID: 34159872
Role of vitamin D in hair loss: A short review.
Saini K, Mysore V
J Cosmet Dermatol 2021 Nov;20(11):3407-3414. Epub 2021 Sep 22 doi: 10.1111/jocd.14421. PMID: 34553483
Oral minoxidil treatment for hair loss: A review of efficacy and safety.
Randolph M, Tosti A
J Am Acad Dermatol 2021 Mar;84(3):737-746. Epub 2020 Jul 2 doi: 10.1016/j.jaad.2020.06.1009. PMID: 32622136
Diagnosing and treating hair loss.
Mounsey AL, Reed SW
Am Fam Physician 2009 Aug 15;80(4):356-62. PMID: 19678603

Prognosis

Post-COVID Telogen Effluvium.
Tešanović Perković D, Vukojević M, Bukvić Mokos Z
Acta Dermatovenerol Croat 2022 Dec;30(4):220-226. PMID: 36919388
Update on trichoscopy: Integration of the terminology by systematic approach and a proposal of a diagnostic flowchart.
Kinoshita-Ise M, Sachdeva M
J Dermatol 2022 Jan;49(1):4-18. Epub 2021 Nov 22 doi: 10.1111/1346-8138.16233. PMID: 34806223
Common causes of hair loss - clinical manifestations, trichoscopy and therapy.
Alessandrini A, Bruni F, Piraccini BM, Starace M
J Eur Acad Dermatol Venereol 2021 Mar;35(3):629-640. Epub 2021 Jan 8 doi: 10.1111/jdv.17079. PMID: 33290611
Evaluation and diagnosis of the hair loss patient: part I. History and clinical examination.
Mubki T, Rudnicka L, Olszewska M, Shapiro J
J Am Acad Dermatol 2014 Sep;71(3):415.e1-415.e15. doi: 10.1016/j.jaad.2014.04.070. PMID: 25128118
Telogen effluvium revisited.
Rebora A
G Ital Dermatol Venereol 2014 Feb;149(1):47-54. PMID: 24566565

Clinical prediction guides

Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study.
Milani M, Colombo F; GFM-O-Trial Investigators Group: Chiara Baraldo (Padova), Mauro Barbareschi (Milano), Paolo Chieco (Ruvo di Puglia), Laura Colonna (Roma), Mandel Victor Desmond (Modena), Maria Cristina Fiorucci (Genova)
Skin Res Technol 2023 Jun;29(6):e13381. doi: 10.1111/srt.13381. PMID: 37357646Free PMC Article
Update on trichoscopy: Integration of the terminology by systematic approach and a proposal of a diagnostic flowchart.
Kinoshita-Ise M, Sachdeva M
J Dermatol 2022 Jan;49(1):4-18. Epub 2021 Nov 22 doi: 10.1111/1346-8138.16233. PMID: 34806223
Telogen effluvium revisited.
Rebora A
G Ital Dermatol Venereol 2014 Feb;149(1):47-54. PMID: 24566565
Drug-induced hair disorders.
Piraccini BM, Iorizzo M, Rech G, Tosti A
Curr Drug Saf 2006 Aug;1(3):301-5. doi: 10.2174/157488606777934477. PMID: 18690941
Telogen effluvium.
Harrison S, Sinclair R
Clin Exp Dermatol 2002 Jul;27(5):389-5. doi: 10.1046/j.1365-2230.2002.01080.x. PMID: 12190639

Recent systematic reviews

Chronic Telogen Effluvium: Is it a Distinct Condition? A Systematic Review.
Daunton A, Harries M, Sinclair R, Paus R, Tosti A, Messenger A
Am J Clin Dermatol 2023 Jul;24(4):513-520. Epub 2023 Apr 13 doi: 10.1007/s40257-023-00760-0. PMID: 37052778
Characteristics of hair loss after COVID-19: A systematic scoping review.
Czech T, Sugihara S, Nishimura Y
J Cosmet Dermatol 2022 Sep;21(9):3655-3662. Epub 2022 Jul 19 doi: 10.1111/jocd.15218. PMID: 35801366Free PMC Article
A systematic review of acute telogen effluvium, a harrowing post-COVID-19 manifestation.
Hussain N, Agarwala P, Iqbal K, Omar HMS, Jangid G, Patel V, Rathore SS, Kumari C, Velasquez-Botero F, López GAB, Vishwakarma Y, Nipu AP, Ahmed NK
J Med Virol 2022 Apr;94(4):1391-1401. Epub 2021 Dec 28 doi: 10.1002/jmv.27534. PMID: 34931698
Update on trichoscopy: Integration of the terminology by systematic approach and a proposal of a diagnostic flowchart.
Kinoshita-Ise M, Sachdeva M
J Dermatol 2022 Jan;49(1):4-18. Epub 2021 Nov 22 doi: 10.1111/1346-8138.16233. PMID: 34806223
Low-dose oral minoxidil as treatment for non-scarring alopecia: a systematic review.
Sharma AN, Michelle L, Juhasz M, Muller Ramos P, Atanaskova Mesinkovska N
Int J Dermatol 2020 Aug;59(8):1013-1019. Epub 2020 Jun 9 doi: 10.1111/ijd.14933. PMID: 32516434

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