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Epithelial hyperplasia of skin

MedGen UID:
538024
•Concept ID:
C0263641
•
Disease or Syndrome
Synonym: Epidermal hyperplasia
SNOMED CT: Epithelial hyperplasia of skin (75307004)

Definition

A hyperplasia of the epidermis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpithelial hyperplasia of skin

Professional guidelines

PubMed

Oral Epithelial Dysplasia: A Review of Diagnostic Criteria for Anatomic Pathologists.
Cheung VKY, Hulme K, Schifter M, Palme C, Low TH, Clark J, Gupta R
Adv Anat Pathol 2022 Jul 1;29(4):227-240. Epub 2022 Apr 19 doi: 10.1097/PAP.0000000000000343. PMID: 35435865
Study regarding the microscopic aspects of pilo-sebaceous units after antiandrogen treatment in hirsute women.
Rotaru M, Totoianu IG, Sin AI, Gheucă Solovăstru L
Rom J Morphol Embryol 2015;56(1):63-9. PMID: 25826488
Current concepts of the pathogenesis of acne: implications for drug treatment.
Gollnick H
Drugs 2003;63(15):1579-96. doi: 10.2165/00003495-200363150-00005. PMID: 12887264

Recent clinical studies

Etiology

Oral Epithelial Dysplasia: A Review of Diagnostic Criteria for Anatomic Pathologists.
Cheung VKY, Hulme K, Schifter M, Palme C, Low TH, Clark J, Gupta R
Adv Anat Pathol 2022 Jul 1;29(4):227-240. Epub 2022 Apr 19 doi: 10.1097/PAP.0000000000000343. PMID: 35435865
Expression of Cyclooxygenase-2 in Human Epithelial Skin Lesions: A Systematic Review of Immunohistochemical Studies.
Kuźbicki Ł, Brożyna AA
Appl Immunohistochem Mol Morphol 2021 Mar 1;29(3):163-174. doi: 10.1097/PAI.0000000000000871. PMID: 32889812
HPV16 E7-Driven Epithelial Hyperplasia Promotes Impaired Antigen Presentation and Regulatory T-Cell Development.
Bashaw AA, Teoh SM, Tuong ZK, Leggatt GR, Frazer IH, Chandra J
J Invest Dermatol 2019 Dec;139(12):2467-2476.e3. Epub 2019 Jun 15 doi: 10.1016/j.jid.2019.03.1162. PMID: 31207230
Human papillomavirus and oral disease - emerging evidence: a review.
Prabhu SR, Wilson DF
Aust Dent J 2013 Mar;58(1):2-10; quiz 125. Epub 2013 Jan 31 doi: 10.1111/adj.12020. PMID: 23441786
Juvenile spongiotic gingivitis.
Darling MR, Daley TD, Wilson A, Wysocki GP
J Periodontol 2007 Jul;78(7):1235-40. doi: 10.1902/jop.2007.060502. PMID: 17608578

Diagnosis

Oral Epithelial Dysplasia: A Review of Diagnostic Criteria for Anatomic Pathologists.
Cheung VKY, Hulme K, Schifter M, Palme C, Low TH, Clark J, Gupta R
Adv Anat Pathol 2022 Jul 1;29(4):227-240. Epub 2022 Apr 19 doi: 10.1097/PAP.0000000000000343. PMID: 35435865
Kappa and lambda immunohistochemistry and in situ hybridization in the evaluation of atypical cutaneous lymphoid infiltrates.
Hristov AC, Comfere NI, Vidal CI, Sundram U
J Cutan Pathol 2020 Nov;47(11):1103-1110. Epub 2020 Sep 14 doi: 10.1111/cup.13858. PMID: 32870521
Human genetic dissection of papillomavirus-driven diseases: new insight into their pathogenesis.
Béziat V
Hum Genet 2020 Jun;139(6-7):919-939. Epub 2020 May 20 doi: 10.1007/s00439-020-02183-x. PMID: 32435828Free PMC Article
Mucocutaneous pseudoepitheliomatous hyperplasia: a review.
El-Khoury J, Kibbi AG, Abbas O
Am J Dermatopathol 2012 Apr;34(2):165-75. doi: 10.1097/DAD.0b013e31821816ab. PMID: 21993336
Juvenile spongiotic gingivitis.
Darling MR, Daley TD, Wilson A, Wysocki GP
J Periodontol 2007 Jul;78(7):1235-40. doi: 10.1902/jop.2007.060502. PMID: 17608578

Therapy

Expression of Cyclooxygenase-2 in Human Epithelial Skin Lesions: A Systematic Review of Immunohistochemical Studies.
Kuźbicki Ł, Brożyna AA
Appl Immunohistochem Mol Morphol 2021 Mar 1;29(3):163-174. doi: 10.1097/PAI.0000000000000871. PMID: 32889812
C3 Drives Inflammatory Skin Carcinogenesis Independently of C5.
Jackson WD, Gulino A, Fossati-Jimack L, Castro Seoane R, Tian K, Best K, Köhl J, Belmonte B, Strid J, Botto M
J Invest Dermatol 2021 Feb;141(2):404-414.e6. Epub 2020 Jul 16 doi: 10.1016/j.jid.2020.06.025. PMID: 32682912Free PMC Article
Photopreventive Effect and Mechanism of AZD4547 and Curcumin C3 Complex on UVB-Induced Epidermal Hyperplasia.
Khandelwal AR, Rong X, Moore-Medlin T, Ekshyyan O, Abreo F, Gu X, Nathan CA
Cancer Prev Res (Phila) 2016 Apr;9(4):296-304. Epub 2016 Feb 9 doi: 10.1158/1940-6207.CAPR-15-0366. PMID: 26862088
Current concepts of the pathogenesis of acne: implications for drug treatment.
Gollnick H
Drugs 2003;63(15):1579-96. doi: 10.2165/00003495-200363150-00005. PMID: 12887264
5alpha-reductase activity in the prostate.
Steers WD
Urology 2001 Dec;58(6 Suppl 1):17-24; discussion 24. doi: 10.1016/s0090-4295(01)01299-7. PMID: 11750244

Prognosis

Actinic cheilitis: Proposal of a clinical index.
Medeiros CK, Lopes ML, Silveira ÉJ, Lima KC, Oliveira PT
Med Oral Patol Oral Cir Bucal 2022 Jul 1;27(4):e310-e318. doi: 10.4317/medoral.25243. PMID: 35660729Free PMC Article
Oral Epithelial Dysplasia: A Review of Diagnostic Criteria for Anatomic Pathologists.
Cheung VKY, Hulme K, Schifter M, Palme C, Low TH, Clark J, Gupta R
Adv Anat Pathol 2022 Jul 1;29(4):227-240. Epub 2022 Apr 19 doi: 10.1097/PAP.0000000000000343. PMID: 35435865
Human genetic dissection of papillomavirus-driven diseases: new insight into their pathogenesis.
Béziat V
Hum Genet 2020 Jun;139(6-7):919-939. Epub 2020 May 20 doi: 10.1007/s00439-020-02183-x. PMID: 32435828Free PMC Article
Columnar Cell Lesion and Apocrine Hyperplasia of the Breast: Is There a Common Origin? The Role of Prolactin-induced Protein.
Sciarra A, Lopez G, Corti C, Runza L, Ercoli G, Bonometti A, Despini L, Blundo C, Gambini D, Fusco N
Appl Immunohistochem Mol Morphol 2019 Aug;27(7):508-514. doi: 10.1097/PAI.0000000000000604. PMID: 29084054
Skin Biopsy in Netherton Syndrome: A Histological Review of a Large Series and New Findings.
Leclerc-Mercier S, Bodemer C, Furio L, Hadj-Rabia S, de Peufeilhoux L, Weibel L, Bursztejn AC, Bourrat E, Ortonne N, Molina TJ, Hovnanian A, Fraitag S
Am J Dermatopathol 2016 Feb;38(2):83-91. doi: 10.1097/DAD.0000000000000425. PMID: 26825155

Clinical prediction guides

Actinic cheilitis: Proposal of a clinical index.
Medeiros CK, Lopes ML, Silveira ÉJ, Lima KC, Oliveira PT
Med Oral Patol Oral Cir Bucal 2022 Jul 1;27(4):e310-e318. doi: 10.4317/medoral.25243. PMID: 35660729Free PMC Article
Oral Epithelial Dysplasia: A Review of Diagnostic Criteria for Anatomic Pathologists.
Cheung VKY, Hulme K, Schifter M, Palme C, Low TH, Clark J, Gupta R
Adv Anat Pathol 2022 Jul 1;29(4):227-240. Epub 2022 Apr 19 doi: 10.1097/PAP.0000000000000343. PMID: 35435865
Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation.
Dwyer DF, Ordovas-Montanes J, Allon SJ, Buchheit KM, Vukovic M, Derakhshan T, Feng C, Lai J, Hughes TK, Nyquist SK, Giannetti MP, Berger B, Bhattacharyya N, Roditi RE, Katz HR, Nawijn MC, Berg M, van den Berge M, Laidlaw TM, Shalek AK, Barrett NA, Boyce JA
Sci Immunol 2021 Feb 26;6(56) doi: 10.1126/sciimmunol.abb7221. PMID: 33637594Free PMC Article
Expression of Cyclooxygenase-2 in Human Epithelial Skin Lesions: A Systematic Review of Immunohistochemical Studies.
Kuźbicki Ł, Brożyna AA
Appl Immunohistochem Mol Morphol 2021 Mar 1;29(3):163-174. doi: 10.1097/PAI.0000000000000871. PMID: 32889812
C3 Drives Inflammatory Skin Carcinogenesis Independently of C5.
Jackson WD, Gulino A, Fossati-Jimack L, Castro Seoane R, Tian K, Best K, Köhl J, Belmonte B, Strid J, Botto M
J Invest Dermatol 2021 Feb;141(2):404-414.e6. Epub 2020 Jul 16 doi: 10.1016/j.jid.2020.06.025. PMID: 32682912Free PMC Article

Recent systematic reviews

Expression of Cyclooxygenase-2 in Human Epithelial Skin Lesions: A Systematic Review of Immunohistochemical Studies.
Kuźbicki Ł, Brożyna AA
Appl Immunohistochem Mol Morphol 2021 Mar 1;29(3):163-174. doi: 10.1097/PAI.0000000000000871. PMID: 32889812

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