U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cleft upper lip, upper jaw AND palate

MedGen UID:
539673
Concept ID:
C0266090
Congenital Abnormality
Synonyms: Cheilognathopalatoschisis; Cheilognathouranoschisis
SNOMED CT: Cheilognathopalatoschisis (337471007); Cleft upper lip, upper jaw AND palate (337471007); Cheilognathouranoschisis (338486003)

Definition

A congenital abnormality consisting of a fissure in the midline of the lip, hard and/or soft palate and upper jaw. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCleft upper lip, upper jaw AND palate

Professional guidelines

PubMed

Fariña R, Lolas J, Moreno E, Alister JP, Uribe MF, Pantoja R, Valladares S, Arrué C
J Craniofac Surg 2022 Mar-Apr 01;33(2):496-501. doi: 10.1097/SCS.0000000000007973. PMID: 34261964
Morris L
Curr Opin Otolaryngol Head Neck Surg 2019 Aug;27(4):302-309. doi: 10.1097/MOO.0000000000000558. PMID: 31219831
Bittermann GK, de Ruiter AP, Janssen NG, Bittermann AJ, van der Molen AM, van Es RJ, Rosenberg AJ, Koole R
Clin Oral Investig 2016 Mar;20(2):207-17. Epub 2015 Sep 16 doi: 10.1007/s00784-015-1589-y. PMID: 26374747Free PMC Article

Recent clinical studies

Etiology

Wlodarczyk JR, Brannon B, Munabi NCO, Wolfswinkel EM, Nagengast ES, Yao CA, Magee W 3rd
J Craniofac Surg 2021 Mar-Apr 01;32(2):647-651. doi: 10.1097/SCS.0000000000007029. PMID: 33705001
Erdur EA, Baka ZM, Fidanboy M, Erdur O
J Craniofac Surg 2019 Sep;30(6):1706-1709. doi: 10.1097/SCS.0000000000005504. PMID: 31033758
Faco R, Yatabe M, Cevidanes LHS, Timmerman H, De Clerck HJ, Garib D
Eur J Orthod 2019 Sep 21;41(5):537-543. doi: 10.1093/ejo/cjz005. PMID: 30865780Free PMC Article
Roy AA, Rtshiladze MA, Stevens K, Phillips J
Clin Plast Surg 2019 Apr;46(2):157-171. Epub 2019 Feb 6 doi: 10.1016/j.cps.2018.11.002. PMID: 30851748
Buschang PH, Porter C, Genecov E, Genecov D, Sayler KE
Angle Orthod 1994;64(2):145-50. doi: 10.1043/0003-3219(1994)064<0145:FMTOPW>2.0.CO;2. PMID: 8010523

Diagnosis

Antonarakis GS, Huanca Ghislanzoni L, Fisher DM
J Stomatol Oral Maxillofac Surg 2022 Nov;123(6):e916-e921. Epub 2022 Jun 10 doi: 10.1016/j.jormas.2022.06.008. PMID: 35697253
Trevizan M, Consolaro A
Dental Press J Orthod 2017 Mar-Apr;22(2):21-26. doi: 10.1590/2177-6709.22.2.021-026.oin. PMID: 28658352Free PMC Article
Sisti A, Freda N, Giacomina A, Gatti GL
J Craniofac Surg 2017 May;28(3):e250-e251. doi: 10.1097/SCS.0000000000003473. PMID: 28468208
Wang XQ, Zhang WF, Wang YG, Bu LL, Hou M
J Craniofac Surg 2016 Nov;27(8):e762-e763. doi: 10.1097/SCS.0000000000003115. PMID: 28005814
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938

Therapy

Shimada E, Kanetaka H, Yamauchi K, Takahashi T, Nochioka K, Igarashi K
BMJ Open 2022 Sep 1;12(9):e061831. doi: 10.1136/bmjopen-2022-061831. PMID: 36581967Free PMC Article
Liu A, Huang J
Cleft Palate Craniofac J 2022 Apr;59(4):442-452. Epub 2021 Jun 8 doi: 10.1177/10556656211018950. PMID: 34098764
Roy AA, Rtshiladze MA, Stevens K, Phillips J
Clin Plast Surg 2019 Apr;46(2):157-171. Epub 2019 Feb 6 doi: 10.1016/j.cps.2018.11.002. PMID: 30851748
Bruggink R, Baan F, Kramer GJC, Maal TJJ, Kuijpers-Jagtman AM, Bergé SJ, Bronkhorst EM, Ongkosuwito EM
Clin Oral Investig 2019 Oct;23(10):3705-3712. Epub 2019 Jan 11 doi: 10.1007/s00784-018-2791-5. PMID: 30635787
Façanha AJ, Lara TS, Garib DG, da Silva Filho OG
Dental Press J Orthod 2014 Mar-Apr;19(2):39-45. doi: 10.1590/2176-9451.19.2.039-045.oar. PMID: 24945513Free PMC Article

Prognosis

Nys M, Bempt MVD, Shaheen E, Dormaar JT, Politis C
J Stomatol Oral Maxillofac Surg 2023 Sep;124(4):101421. Epub 2023 Feb 9 doi: 10.1016/j.jormas.2023.101421. PMID: 36764580
Antonarakis GS, Huanca Ghislanzoni L, Fisher DM
J Stomatol Oral Maxillofac Surg 2022 Nov;123(6):e916-e921. Epub 2022 Jun 10 doi: 10.1016/j.jormas.2022.06.008. PMID: 35697253
Veitz-Keenan A, Liu N
Evid Based Dent 2019 Sep;20(3):72-73. doi: 10.1038/s41432-019-0049-y. PMID: 31562403
Richardson S, Selvaraj D, Khandeparker RV, Seelan NS, Richardson S
J Oral Maxillofac Surg 2016 Dec;74(12):2504.e1-2504.e14. Epub 2016 Aug 31 doi: 10.1016/j.joms.2016.08.036. PMID: 27669372
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938

Clinical prediction guides

Antonarakis GS, Huanca Ghislanzoni L, Fisher DM
J Stomatol Oral Maxillofac Surg 2022 Nov;123(6):e916-e921. Epub 2022 Jun 10 doi: 10.1016/j.jormas.2022.06.008. PMID: 35697253
Liu A, Huang J
Cleft Palate Craniofac J 2022 Apr;59(4):442-452. Epub 2021 Jun 8 doi: 10.1177/10556656211018950. PMID: 34098764
Sales PHH, Costa FWG, Cetira Filho EL, Silva PGB, Albuquerque AFM, Leão JC
Int J Oral Maxillofac Surg 2021 Jan;50(1):64-74. Epub 2020 Aug 12 doi: 10.1016/j.ijom.2020.07.030. PMID: 32798160
Gilbert F, Leclerc JE, Deschênes M, Julien AS, Grenier-Ouellette I
Cleft Palate Craniofac J 2020 Jul;57(7):819-827. Epub 2020 Feb 11 doi: 10.1177/1055665619900865. PMID: 32041415
Faco R, Yatabe M, Cevidanes LHS, Timmerman H, De Clerck HJ, Garib D
Eur J Orthod 2019 Sep 21;41(5):537-543. doi: 10.1093/ejo/cjz005. PMID: 30865780Free PMC Article

Recent systematic reviews

Le Y, Li M, Li F, Wu S, Zhu C, Wan Q
Eur J Orthod 2024 Jan 1;46(1) doi: 10.1093/ejo/cjad081. PMID: 38168816
Salgado KR, Wendt AR, Fernandes Fagundes NC, Maia LC, Normando D, Leão PB
J Craniomaxillofac Surg 2019 Nov;47(11):1690-1698. Epub 2019 Jul 3 doi: 10.1016/j.jcms.2019.06.017. PMID: 31677987
Dos Santos Alves JM, de Freitas Alves BW, de Figueiredo Costa AC, Carneiro BGDS, de Sousa LM, Gondim DV
Int J Oral Maxillofac Surg 2019 May;48(5):601-611. Epub 2018 Dec 28 doi: 10.1016/j.ijom.2018.11.012. PMID: 30598335
Reddy RR, Gosla Reddy S, Vaidhyanathan A, Bergé SJ, Kuijpers-Jagtman AM
J Craniomaxillofac Surg 2017 Jun;45(6):995-1003. Epub 2017 Mar 22 doi: 10.1016/j.jcms.2017.03.006. PMID: 28427835
Thierens L, Brusselaers N, De Roo N, De Pauw G
Oral Dis 2017 Oct;23(7):889-896. Epub 2017 Jan 24 doi: 10.1111/odi.12613. PMID: 27878905

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...