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Acidemia

MedGen UID:
541142
Concept ID:
C0268030
Pathologic Function
SNOMED CT: Acidemia (70731005)
 
HPO: HP:0032368

Definition

An abnormally low blood pH (usually defined as less than 7.35). [from HPO]

Professional guidelines

PubMed

Olofsson P
Am J Obstet Gynecol 2023 May;228(5S):S1222-S1240. Epub 2023 Mar 19 doi: 10.1016/j.ajog.2022.07.001. PMID: 37164495
El-Hattab AW, Adesina AM, Jones J, Scaglia F
Mol Genet Metab 2015 Sep-Oct;116(1-2):4-12. Epub 2015 Jun 15 doi: 10.1016/j.ymgme.2015.06.004. PMID: 26095523
Baumgartner MR, Hörster F, Dionisi-Vici C, Haliloglu G, Karall D, Chapman KA, Huemer M, Hochuli M, Assoun M, Ballhausen D, Burlina A, Fowler B, Grünert SC, Grünewald S, Honzik T, Merinero B, Pérez-Cerdá C, Scholl-Bürgi S, Skovby F, Wijburg F, MacDonald A, Martinelli D, Sass JO, Valayannopoulos V, Chakrapani A
Orphanet J Rare Dis 2014 Sep 2;9:130. doi: 10.1186/s13023-014-0130-8. PMID: 25205257Free PMC Article

Recent clinical studies

Etiology

Zhang Y, Peng C, Wang L, Chen S, Wang J, Tian Z, Wang C, Chen X, Zhu S, Zhang GF, Wang Y
Orphanet J Rare Dis 2023 Sep 9;18(1):281. doi: 10.1186/s13023-023-02898-w. PMID: 37689673Free PMC Article
Baschat AA, Galan HL, Lee W, DeVore GR, Mari G, Hobbins J, Vintzileos A, Platt LD, Manning FA
Am J Obstet Gynecol 2022 Apr;226(4):475-486. doi: 10.1016/j.ajog.2022.01.020. PMID: 35369904
Yu Y, Shuai R, Liang L, Qiu W, Shen L, Wu S, Wei H, Chen Y, Yang C, Xu P, Chen X, Zou H, Feng J, Niu T, Hu H, Ye J, Zhang H, Lu D, Gong Z, Zhan X, Ji W, Gu X, Han L
Mol Genet Genomic Med 2021 Nov;9(11):e1822. Epub 2021 Oct 20 doi: 10.1002/mgg3.1822. PMID: 34668645Free PMC Article
Chand R, Swenson ER, Goldfarb DS
Curr Opin Nephrol Hypertens 2021 Mar 1;30(2):223-230. doi: 10.1097/MNH.0000000000000687. PMID: 33395037
Zayed H
Gene 2015 Jun 15;564(2):119-24. Epub 2015 Apr 9 doi: 10.1016/j.gene.2015.04.019. PMID: 25865301

Diagnosis

Achanti A, Szerlip HM
Clin J Am Soc Nephrol 2023 Jan 1;18(1):102-112. Epub 2022 Aug 23 doi: 10.2215/CJN.04500422. PMID: 35998977Free PMC Article
Forny P, Hörster F, Ballhausen D, Chakrapani A, Chapman KA, Dionisi-Vici C, Dixon M, Grünert SC, Grunewald S, Haliloglu G, Hochuli M, Honzik T, Karall D, Martinelli D, Molema F, Sass JO, Scholl-Bürgi S, Tal G, Williams M, Huemer M, Baumgartner MR
J Inherit Metab Dis 2021 May;44(3):566-592. Epub 2021 Mar 9 doi: 10.1002/jimd.12370. PMID: 33595124Free PMC Article
Mahmud S, Awais Ul Hassan Shah S, Ali S
J Coll Physicians Surg Pak 2015 Jun;25(6):462-4. PMID: 26101005
Baumgartner MR, Hörster F, Dionisi-Vici C, Haliloglu G, Karall D, Chapman KA, Huemer M, Hochuli M, Assoun M, Ballhausen D, Burlina A, Fowler B, Grünert SC, Grünewald S, Honzik T, Merinero B, Pérez-Cerdá C, Scholl-Bürgi S, Skovby F, Wijburg F, MacDonald A, Martinelli D, Sass JO, Valayannopoulos V, Chakrapani A
Orphanet J Rare Dis 2014 Sep 2;9:130. doi: 10.1186/s13023-014-0130-8. PMID: 25205257Free PMC Article
Wiener SW
Emerg Med Clin North Am 2014 Feb;32(1):149-65. doi: 10.1016/j.emc.2013.09.011. PMID: 24275173

Therapy

Gallo DM, Romero R, Bosco M, Gotsch F, Jaiman S, Jung E, Suksai M, Ramón Y Cajal CL, Yoon BH, Chaiworapongsa T
Am J Obstet Gynecol 2023 May;228(5S):S1158-S1178. Epub 2023 Apr 1 doi: 10.1016/j.ajog.2022.11.1283. PMID: 37012128Free PMC Article
Achanti A, Szerlip HM
Clin J Am Soc Nephrol 2023 Jan 1;18(1):102-112. Epub 2022 Aug 23 doi: 10.2215/CJN.04500422. PMID: 35998977Free PMC Article
Chand R, Swenson ER, Goldfarb DS
Curr Opin Nephrol Hypertens 2021 Mar 1;30(2):223-230. doi: 10.1097/MNH.0000000000000687. PMID: 33395037
Merelman AH, Perlmutter MC, Strayer RJ
West J Emerg Med 2019 May;20(3):466-471. Epub 2019 Apr 26 doi: 10.5811/westjem.2019.4.42753. PMID: 31123547Free PMC Article
Wang GS, Hoyte C
J Intensive Care Med 2019 Nov-Dec;34(11-12):863-876. Epub 2018 Aug 21 doi: 10.1177/0885066618793385. PMID: 30126348

Prognosis

Zhang Y, Peng C, Wang L, Chen S, Wang J, Tian Z, Wang C, Chen X, Zhu S, Zhang GF, Wang Y
Orphanet J Rare Dis 2023 Sep 9;18(1):281. doi: 10.1186/s13023-023-02898-w. PMID: 37689673Free PMC Article
Attarwala H, Lumley M, Liang M, Ivaturi V, Senn J
Nucleic Acid Ther 2023 Apr;33(2):141-147. Epub 2022 Dec 27 doi: 10.1089/nat.2022.0036. PMID: 36577040Free PMC Article
Baschat AA, Galan HL, Lee W, DeVore GR, Mari G, Hobbins J, Vintzileos A, Platt LD, Manning FA
Am J Obstet Gynecol 2022 Apr;226(4):475-486. doi: 10.1016/j.ajog.2022.01.020. PMID: 35369904
Gimovsky AC
Am J Obstet Gynecol MFM 2021 Nov;3(6S):100438. Epub 2021 Jul 22 doi: 10.1016/j.ajogmf.2021.100438. PMID: 34302995
Mahmud S, Awais Ul Hassan Shah S, Ali S
J Coll Physicians Surg Pak 2015 Jun;25(6):462-4. PMID: 26101005

Clinical prediction guides

Hermesch AC, Kernberg AS, Layoun VR, Caughey AB
Am J Obstet Gynecol 2024 Mar;230(3S):S729-S739. Epub 2023 Jul 16 doi: 10.1016/j.ajog.2023.06.041. PMID: 37460365
Head PE, Meier JL, Venditti CP
J Inherit Metab Dis 2023 May;46(3):436-449. doi: 10.1002/jimd.12617. PMID: 37078237Free PMC Article
Attarwala H, Lumley M, Liang M, Ivaturi V, Senn J
Nucleic Acid Ther 2023 Apr;33(2):141-147. Epub 2022 Dec 27 doi: 10.1089/nat.2022.0036. PMID: 36577040Free PMC Article
Baschat AA, Galan HL, Lee W, DeVore GR, Mari G, Hobbins J, Vintzileos A, Platt LD, Manning FA
Am J Obstet Gynecol 2022 Apr;226(4):475-486. doi: 10.1016/j.ajog.2022.01.020. PMID: 35369904
Gattinoni L, Vasques F, Camporota L, Meessen J, Romitti F, Pasticci I, Duscio E, Vassalli F, Forni LG, Payen D, Cressoni M, Zanella A, Latini R, Quintel M, Marini JJ
Am J Respir Crit Care Med 2019 Sep 1;200(5):582-589. doi: 10.1164/rccm.201812-2342OC. PMID: 30985210

Recent systematic reviews

Arhip L, Brox-Torrecilla N, Romero I, Motilla M, Serrano-Moreno C, Miguélez M, Cuerda C
Orphanet J Rare Dis 2024 Jan 20;19(1):20. doi: 10.1186/s13023-024-03021-3. PMID: 38245797Free PMC Article
Gallo DM, Romero R, Bosco M, Gotsch F, Jaiman S, Jung E, Suksai M, Ramón Y Cajal CL, Yoon BH, Chaiworapongsa T
Am J Obstet Gynecol 2023 May;228(5S):S1158-S1178. Epub 2023 Apr 1 doi: 10.1016/j.ajog.2022.11.1283. PMID: 37012128Free PMC Article
Jiang YZ, Zhou GP, Wu SS, Kong YY, Zhu ZJ, Sun LY
Transplant Rev (Orlando) 2021 Jan;35(1):100592. Epub 2020 Dec 18 doi: 10.1016/j.trre.2020.100592. PMID: 33422927
Almási T, Guey LT, Lukacs C, Csetneki K, Vokó Z, Zelei T
Orphanet J Rare Dis 2019 Feb 13;14(1):40. doi: 10.1186/s13023-018-0987-z. PMID: 30760309Free PMC Article
Sutton VR, Chapman KA, Gropman AL, MacLeod E, Stagni K, Summar ML, Ueda K, Ah Mew N, Franks J, Island E, Matern D, Peña L, Smith B, Urv T, Venditti C, Chakarapani A
Mol Genet Metab 2012 Jan;105(1):26-33. Epub 2011 Sep 10 doi: 10.1016/j.ymgme.2011.08.034. PMID: 21963082

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