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Vaginal adenosis

MedGen UID:
541820
Concept ID:
C0269214
Disease or Syndrome
Synonym: Vaginal Adenosis
SNOMED CT: Vaginal adenosis (37956000)
 
HPO: HP:0025485

Definition

Vaginal adenosis is defined by the presence of metaplastic cervical or endometrial epithelium within the vaginal wall, thought to be derived from persistent Müllerian (synonymous with paramesonephric) epithelium islets in postembryonic life. [from HPO]

Professional guidelines

PubMed

Wong RW, Moore M, Talia KL, Ganesan R, McCluggage WG
Am J Surg Pathol 2018 Jul;42(7):958-970. doi: 10.1097/PAS.0000000000001068. PMID: 29664741
Gunning JE, Ostegard DR
Obstet Gynecol 1976 Mar;47(3):268-71. PMID: 55991
Scott JW, Seckinger D, Puente-Duany W
J Reprod Med 1974 May;12(5):187-93. PMID: 4838312

Recent clinical studies

Etiology

Han T, Jin Y, Li Y, Bi Y, Pan L
Medicine (Baltimore) 2018 Dec;97(49):e13470. doi: 10.1097/MD.0000000000013470. PMID: 30544435Free PMC Article
Kranl C, Zelger B, Kofler H, Heim K, Sepp N, Fritsch P
Br J Dermatol 1998 Jul;139(1):128-31. doi: 10.1046/j.1365-2133.1998.02329.x. PMID: 9764164
Mittendorf R
Teratology 1995 Jun;51(6):435-45. doi: 10.1002/tera.1420510609. PMID: 7502243
Vessey MP
IARC Sci Publ 1989;(96):335-48. PMID: 2680951
Herbst AL
Obstet Gynecol Annu 1981;10:267-78. PMID: 7024873

Diagnosis

Pang L, Li L, Zhu L, Lang J, Bi Y
BMC Cancer 2019 Aug 13;19(1):798. doi: 10.1186/s12885-019-6026-1. PMID: 31409310Free PMC Article
Han T, Jin Y, Li Y, Bi Y, Pan L
Medicine (Baltimore) 2018 Dec;97(49):e13470. doi: 10.1097/MD.0000000000013470. PMID: 30544435Free PMC Article
Wong RW, Moore M, Talia KL, Ganesan R, McCluggage WG
Am J Surg Pathol 2018 Jul;42(7):958-970. doi: 10.1097/PAS.0000000000001068. PMID: 29664741
Laronda MM, Unno K, Butler LM, Kurita T
Differentiation 2012 Oct;84(3):252-60. Epub 2012 Jun 6 doi: 10.1016/j.diff.2012.05.004. PMID: 22682699Free PMC Article
Herbst AL, Scully RE, Robboy SJ
Clin Obstet Gynecol 1975 Sep;18(3):185-94. doi: 10.1097/00003081-197509000-00021. PMID: 1157359

Therapy

Egger EK, Ralser DJ, Lindner K, Recker F, Marinova M, Savchenko O, Lau JF, Mustea A
Front Immunol 2021;12:686879. Epub 2021 Jul 23 doi: 10.3389/fimmu.2021.686879. PMID: 34367146Free PMC Article
Pang L, Li L, Zhu L, Lang J, Bi Y
BMC Cancer 2019 Aug 13;19(1):798. doi: 10.1186/s12885-019-6026-1. PMID: 31409310Free PMC Article
Laronda MM, Unno K, Butler LM, Kurita T
Differentiation 2012 Oct;84(3):252-60. Epub 2012 Jun 6 doi: 10.1016/j.diff.2012.05.004. PMID: 22682699Free PMC Article
Goodman A, Zukerberg LR, Nikrui N, Scully RE
Cancer 1991 Oct 1;68(7):1628-32. doi: 10.1002/1097-0142(19911001)68:7<1628::aid-cncr2820680727>3.0.co;2-r. PMID: 1893363
Herbst AL, Scully RE, Robboy SJ
Clin Obstet Gynecol 1975 Sep;18(3):185-94. doi: 10.1097/00003081-197509000-00021. PMID: 1157359

Prognosis

Egger EK, Ralser DJ, Lindner K, Recker F, Marinova M, Savchenko O, Lau JF, Mustea A
Front Immunol 2021;12:686879. Epub 2021 Jul 23 doi: 10.3389/fimmu.2021.686879. PMID: 34367146Free PMC Article
Han T, Jin Y, Li Y, Bi Y, Pan L
Medicine (Baltimore) 2018 Dec;97(49):e13470. doi: 10.1097/MD.0000000000013470. PMID: 30544435Free PMC Article
Wong RW, Moore M, Talia KL, Ganesan R, McCluggage WG
Am J Surg Pathol 2018 Jul;42(7):958-970. doi: 10.1097/PAS.0000000000001068. PMID: 29664741
Paczos TA, Ackers S, Odunsi K, Lele S, Mhawech-Fauceglia P
Int J Gynecol Pathol 2010 Mar;29(2):193-6. doi: 10.1097/PGP.0b013e3181b6a7d7. PMID: 20173507Free PMC Article
Emens M
Br J Hosp Med 1984 Jan;31(1):42-8. PMID: 6697040

Clinical prediction guides

Egger EK, Ralser DJ, Lindner K, Recker F, Marinova M, Savchenko O, Lau JF, Mustea A
Front Immunol 2021;12:686879. Epub 2021 Jul 23 doi: 10.3389/fimmu.2021.686879. PMID: 34367146Free PMC Article
Wong RW, Moore M, Talia KL, Ganesan R, McCluggage WG
Am J Surg Pathol 2018 Jul;42(7):958-970. doi: 10.1097/PAS.0000000000001068. PMID: 29664741
Val-Bernal JF, Mayorga M
Pathol Res Pract 2016 Jun;212(6):568-72. Epub 2016 Feb 26 doi: 10.1016/j.prp.2016.02.023. PMID: 26970930
Herbst AL
Obstet Gynecol Annu 1981;10:267-78. PMID: 7024873
Stafl A, Mattingly RF, Foley DV, Fetherston WC
Obstet Gynecol 1974 Jan;43(1):118-28. PMID: 4808952

Recent systematic reviews

Reich O, Fritsch H
J Low Genit Tract Dis 2014 Oct;18(4):358-60. doi: 10.1097/LGT.0000000000000023. PMID: 24977630

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